ATE208210T1 - Kombination von proteintyrosin-kinaseinhibitoren und chemischer kastration zur behandlung von prostatakrebs - Google Patents
Kombination von proteintyrosin-kinaseinhibitoren und chemischer kastration zur behandlung von prostatakrebsInfo
- Publication number
- ATE208210T1 ATE208210T1 AT98942057T AT98942057T ATE208210T1 AT E208210 T1 ATE208210 T1 AT E208210T1 AT 98942057 T AT98942057 T AT 98942057T AT 98942057 T AT98942057 T AT 98942057T AT E208210 T1 ATE208210 T1 AT E208210T1
- Authority
- AT
- Austria
- Prior art keywords
- tyrosine kinase
- prostate cancer
- treatment
- combination
- chemical castration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5589197P | 1997-08-15 | 1997-08-15 | |
PCT/US1998/016849 WO1999008668A2 (en) | 1997-08-15 | 1998-08-13 | Combination of tyrosine kinase inhibitor and chemical castration to treat prostate cancer |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE208210T1 true ATE208210T1 (de) | 2001-11-15 |
Family
ID=22000842
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98942057T ATE208210T1 (de) | 1997-08-15 | 1998-08-13 | Kombination von proteintyrosin-kinaseinhibitoren und chemischer kastration zur behandlung von prostatakrebs |
Country Status (23)
Country | Link |
---|---|
US (1) | US5985877A (de) |
EP (1) | EP1011648B2 (de) |
JP (1) | JP2001515032A (de) |
KR (1) | KR100612161B1 (de) |
CN (1) | CN1147317C (de) |
AT (1) | ATE208210T1 (de) |
AU (1) | AU737092B2 (de) |
BR (1) | BR9812122A (de) |
CA (1) | CA2299471C (de) |
CZ (1) | CZ297198B6 (de) |
DE (1) | DE69802422T3 (de) |
DK (1) | DK1011648T4 (de) |
EA (1) | EA002525B1 (de) |
ES (1) | ES2163293T5 (de) |
HK (1) | HK1028565A1 (de) |
HU (1) | HUP0003194A3 (de) |
NO (1) | NO325526B1 (de) |
NZ (2) | NZ517497A (de) |
PL (1) | PL193375B1 (de) |
PT (1) | PT1011648E (de) |
TR (1) | TR200000415T2 (de) |
UA (1) | UA61970C2 (de) |
WO (1) | WO1999008668A2 (de) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1322139A (zh) * | 1998-10-08 | 2001-11-14 | 武田药品工业株式会社 | 阻滞激素依赖性癌症向激素非依赖性癌症转化的药物 |
GB0007371D0 (en) * | 2000-03-28 | 2000-05-17 | Astrazeneca Uk Ltd | Chemical compounds |
GB0008368D0 (en) * | 2000-04-06 | 2000-05-24 | Astrazeneca Ab | Combination product |
US20020169154A1 (en) * | 2001-04-04 | 2002-11-14 | Cephalon, Inc. | Novel methods and compositions involving trk tyrosine kinase inhibitors and antineoplastic agents |
CA2449166A1 (en) * | 2001-05-08 | 2002-11-14 | Merck Patent Gesellschaft Mit Beschraenkter Haftung | Combination therapy using anti-egfr antibodies and anti-hormonal agents |
SE0101697D0 (sv) * | 2001-05-14 | 2001-05-14 | Astrazeneca Ab | Pharmaceutical combination |
IL144583A0 (en) | 2001-07-26 | 2002-05-23 | Peptor Ltd | Chimeric protein kinase inhibitors |
WO2003015820A1 (fr) * | 2001-08-10 | 2003-02-27 | Takeda Chemical Industries, Ltd. | Medicaments combines d'agoniste de la gnrh |
WO2003018611A2 (en) * | 2001-08-24 | 2003-03-06 | University Of Victoria Innovation And Development Corporation | Proaerolysin containing protease activation sequences and methods of use for treatment of prostate cancer |
US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
US7425618B2 (en) | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
US8034831B2 (en) | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
US7563810B2 (en) | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
KR101224235B1 (ko) | 2003-04-11 | 2013-01-25 | 메디뮨 엘엘씨 | 재조합 il9 항체 및 그의 용도 |
US20040224000A1 (en) * | 2003-05-05 | 2004-11-11 | Romano Deghenghi | Implants for non-radioactive brachytherapy of hormonal-insensitive cancers |
IL156429A0 (en) * | 2003-06-12 | 2004-01-04 | Peptor Ltd | Cell permeable conjugates of peptides for inhibition of protein kinases |
EP2272566A3 (de) | 2003-08-18 | 2013-01-02 | MedImmune, LLC | Humanisierung von antikörpern |
CA2585717A1 (en) | 2004-10-27 | 2006-05-04 | Medimmune Inc. | Modulation of antibody specificity by tailoring the affinity to cognate antigens |
JP5153613B2 (ja) | 2005-03-18 | 2013-02-27 | メディミューン,エルエルシー | 抗体のフレームワーク・シャッフル |
AU2006257664B2 (en) | 2005-06-14 | 2013-01-10 | Protox Therapeutics Incorporated | Method of treating or preventing benign prostatic hyperplasia using modified pore-forming proteins |
KR20080025174A (ko) | 2005-06-23 | 2008-03-19 | 메디뮨 인코포레이티드 | 응집 및 단편화 프로파일이 최적화된 항체 제제 |
CA2641310C (en) * | 2006-02-03 | 2013-08-20 | Imclone Systems Incorporated | Igf-ir antagonists as adjuvants for treatment of prostate cancer |
US20080021013A1 (en) * | 2006-07-21 | 2008-01-24 | Cephalon, Inc. | JAK inhibitors for treatment of myeloproliferative disorders |
EP2064243A2 (de) | 2006-08-28 | 2009-06-03 | Kyowa Hakko Kirin Co., Ltd. | Antagonistische lichtspezifische menschliche monoklonale antikörper |
JP5456658B2 (ja) | 2007-03-30 | 2014-04-02 | メディミューン,エルエルシー | 抗体製剤 |
US20090130195A1 (en) * | 2007-10-17 | 2009-05-21 | Mildred Acevedo-Duncan | Prostate carcinogenesis predictor |
EP2668210B1 (de) | 2011-01-26 | 2020-06-17 | Celldex Therapeutics, Inc. | Anti-kit-antikörper und ihre verwendungen |
US9334332B2 (en) | 2012-07-25 | 2016-05-10 | Kolltan Pharmaceuticals, Inc. | Anti-kit antibodies |
WO2014059028A1 (en) | 2012-10-09 | 2014-04-17 | Igenica, Inc. | Anti-c16orf54 antibodies and methods of use thereof |
SG11201509982UA (de) | 2013-06-06 | 2016-04-28 | Igenica Biotherapeutics Inc | |
RU2699289C2 (ru) | 2013-08-26 | 2019-09-04 | Байонтек Рисерч Энд Дивелопмент, Инк. | НУКЛЕИНОВЫЕ КИСЛОТЫ, КОДИРУЮЩИЕ АНТИТЕЛА ПРОТИВ СИАЛИРОВАННОГО АНТИГЕНА ЛЬЮИСАа ЧЕЛОВЕКА |
GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
PT3154583T (pt) | 2014-06-04 | 2021-03-24 | Biontech Res And Development Inc | Anticorpos monoclonais humanos para o gangliósido gd2 |
EP3229838B1 (de) | 2014-12-11 | 2020-09-09 | Pierre Fabre Medicament | Anti-c10orf54-antikörper und verwendungen davon |
WO2016139482A1 (en) | 2015-03-03 | 2016-09-09 | Kymab Limited | Antibodies, uses & methods |
EP3302568B1 (de) | 2015-05-29 | 2023-12-06 | Memorial Sloan Kettering Cancer Center | Verfahren zur behandlung mithilfe von ultrakleinen nanopartikeln zur induktion des zelltods von nährstoffentzogenen krebszellen über ferroptose |
AU2016365318B2 (en) | 2015-12-02 | 2024-04-18 | Board Of Regents, The University Of Texas System | Antibodies and molecules that immunospecifically bind to BTN1A1 and the therapeutic uses thereof |
KR20180100122A (ko) | 2015-12-02 | 2018-09-07 | 주식회사 에스티사이언스 | 당화된 btla(b- 및 t-림프구 약화인자)에 특이적인 항체 |
US11779604B2 (en) | 2016-11-03 | 2023-10-10 | Kymab Limited | Antibodies, combinations comprising antibodies, biomarkers, uses and methods |
AU2018271781A1 (en) | 2017-05-25 | 2019-12-12 | Cornell University | Ultrasmall nanoparticles labeled with Zirconium-89 and methods thereof |
EP3630834A1 (de) | 2017-05-31 | 2020-04-08 | STCube & Co., Inc. | Verfahren zur behandlung von krebs mit antikörpern und molekülen, die immunspezifisch an btn1a1 binden |
EP3630835A1 (de) | 2017-05-31 | 2020-04-08 | STCube & Co., Inc. | Antikörper und moleküle, die immunspezifisch an btn1a1 binden, und therapeutische verwendungen davon |
CN110997724A (zh) | 2017-06-06 | 2020-04-10 | 斯特库伯株式会社 | 使用结合btn1a1或btn1a1-配体的抗体和分子治疗癌症的方法 |
RU2667906C1 (ru) * | 2017-09-11 | 2018-09-25 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ онкологии им. Н.Н. Блохина" Минздрава России) | Производное класса N-гликозидов индоло[2,3-а]пирроло[3,4-с]карбазол-5,7-дионов - N-{ 12-(β-D-ксилопиранозил)-5,7-диоксо-индоло[2,3-а]пирроло[3,4-с] карбазол-6-ил} пиридин-2-карбоксамид, обладающее цитотоксической и противоопухолевой активностью |
US11707522B2 (en) | 2017-10-13 | 2023-07-25 | Boehringer Ingelheim International Gmbh | Human antibodies to Tn antigen |
BR112021000934A2 (pt) | 2018-07-20 | 2021-04-27 | Pierre Fabre Medicament | receptor para vista |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4659695A (en) * | 1985-02-08 | 1987-04-21 | Fernand Labrie | Method of treatment of prostate cancer |
EP0303697B1 (de) * | 1987-03-09 | 1997-10-01 | Kyowa Hakko Kogyo Co., Ltd. | Derivate des physiologisch aktiven mittels k-252 |
AU661533B2 (en) * | 1992-01-20 | 1995-07-27 | Astrazeneca Ab | Quinazoline derivatives |
US5461146A (en) † | 1992-07-24 | 1995-10-24 | Cephalon, Inc. | Selected protein kinase inhibitors for the treatment of neurological disorders |
CA2163904C (en) * | 1993-05-28 | 2000-01-25 | Craig A. Dionne | Use of indolocarbazole derivatives to treat a pathological condition of the prostate |
WO1995024190A2 (en) * | 1994-03-07 | 1995-09-14 | Sugen, Inc. | Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof |
SE506019C2 (sv) * | 1994-05-17 | 1997-11-03 | Forskarpatent I Linkoeping Ab | Ljuskälla av konjugerade polymerer med spänningsstyrd färg samt metod för tillverkning av ljuskällan |
US5475110A (en) * | 1994-10-14 | 1995-12-12 | Cephalon, Inc. | Fused Pyrrolocarbazoles |
US5705511A (en) * | 1994-10-14 | 1998-01-06 | Cephalon, Inc. | Fused pyrrolocarbazoles |
US5594009A (en) * | 1994-10-14 | 1997-01-14 | Cephalon, Inc. | Fused pyrrolocarbazoles |
US5591855A (en) * | 1994-10-14 | 1997-01-07 | Cephalon, Inc. | Fused pyrrolocarbazoles |
US5650407A (en) * | 1995-04-05 | 1997-07-22 | Cephalon, Inc. | Selected soluble esters of hydroxyl-containing indolocarbazoles |
GB9508538D0 (en) † | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
US5659407A (en) * | 1995-06-06 | 1997-08-19 | Apple Computer, Inc. | Method and system for rendering achromatic image data for image output devices |
CN1077107C (zh) † | 1996-07-19 | 2002-01-02 | 武田药品工业株式会社 | 杂环化合物、其制备和用途 |
-
1998
- 1998-08-13 HU HU0003194A patent/HUP0003194A3/hu unknown
- 1998-08-13 CZ CZ20000469A patent/CZ297198B6/cs not_active IP Right Cessation
- 1998-08-13 JP JP2000509408A patent/JP2001515032A/ja active Pending
- 1998-08-13 TR TR2000/00415T patent/TR200000415T2/xx unknown
- 1998-08-13 US US09/133,567 patent/US5985877A/en not_active Expired - Fee Related
- 1998-08-13 EP EP98942057A patent/EP1011648B2/de not_active Expired - Lifetime
- 1998-08-13 NZ NZ517497A patent/NZ517497A/en unknown
- 1998-08-13 PL PL98338885A patent/PL193375B1/pl not_active IP Right Cessation
- 1998-08-13 AT AT98942057T patent/ATE208210T1/de not_active IP Right Cessation
- 1998-08-13 AU AU90192/98A patent/AU737092B2/en not_active Ceased
- 1998-08-13 UA UA2000031438A patent/UA61970C2/uk unknown
- 1998-08-13 BR BR9812122-7A patent/BR9812122A/pt not_active IP Right Cessation
- 1998-08-13 DE DE69802422T patent/DE69802422T3/de not_active Expired - Lifetime
- 1998-08-13 WO PCT/US1998/016849 patent/WO1999008668A2/en active IP Right Grant
- 1998-08-13 ES ES98942057T patent/ES2163293T5/es not_active Expired - Lifetime
- 1998-08-13 NZ NZ502646A patent/NZ502646A/en unknown
- 1998-08-13 CA CA002299471A patent/CA2299471C/en not_active Expired - Fee Related
- 1998-08-13 PT PT98942057T patent/PT1011648E/pt unknown
- 1998-08-13 KR KR1020007001481A patent/KR100612161B1/ko not_active IP Right Cessation
- 1998-08-13 EA EA200000220A patent/EA002525B1/ru not_active IP Right Cessation
- 1998-08-13 DK DK98942057T patent/DK1011648T4/da active
- 1998-08-13 CN CNB988081741A patent/CN1147317C/zh not_active Expired - Fee Related
-
2000
- 2000-02-14 NO NO20000732A patent/NO325526B1/no not_active IP Right Cessation
- 2000-12-13 HK HK00108007A patent/HK1028565A1/xx not_active IP Right Cessation
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