TR200000415T2 - Prostat kanserinin tedavi edilmesi için birleşimler. - Google Patents
Prostat kanserinin tedavi edilmesi için birleşimler.Info
- Publication number
- TR200000415T2 TR200000415T2 TR2000/00415T TR200000415T TR200000415T2 TR 200000415 T2 TR200000415 T2 TR 200000415T2 TR 2000/00415 T TR2000/00415 T TR 2000/00415T TR 200000415 T TR200000415 T TR 200000415T TR 200000415 T2 TR200000415 T2 TR 200000415T2
- Authority
- TR
- Turkey
- Prior art keywords
- prostate cancer
- combinations
- treat prostate
- tyrosine kinase
- kinase inhibitor
- Prior art date
Links
- 206010060862 Prostate cancer Diseases 0.000 title abstract 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 title abstract 2
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- 229940121358 tyrosine kinase inhibitor Drugs 0.000 abstract 2
- 239000005483 tyrosine kinase inhibitor Substances 0.000 abstract 2
- 150000004917 tyrosine kinase inhibitor derivatives Chemical class 0.000 abstract 2
- 238000011260 co-administration Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- VVVPGLRKXQSQSZ-UHFFFAOYSA-N indolo[3,2-c]carbazole Chemical compound C1=CC=CC2=NC3=C4C5=CC=CC=C5N=C4C=CC3=C21 VVVPGLRKXQSQSZ-UHFFFAOYSA-N 0.000 abstract 1
- 229960005544 indolocarbazole Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Prostat kanserinin, bir indolokarbazol olarak bir tirosin kinaz önleyiciyle ve bir kimyasal hadim etme madesinin birlikte uygulanmasiyla tedavi edilmesi için bir yöntem anlatilir. Bir tirosin kinaz önleyici ve bir kimyasal hadim etme maddesi içeren bir bilesik de ayrica anlatilir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5589197P | 1997-08-15 | 1997-08-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200000415T2 true TR200000415T2 (tr) | 2000-08-21 |
Family
ID=22000842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/00415T TR200000415T2 (tr) | 1997-08-15 | 1998-08-13 | Prostat kanserinin tedavi edilmesi için birleşimler. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US5985877A (tr) |
| EP (1) | EP1011648B2 (tr) |
| JP (1) | JP2001515032A (tr) |
| KR (1) | KR100612161B1 (tr) |
| CN (1) | CN1147317C (tr) |
| AT (1) | ATE208210T1 (tr) |
| AU (1) | AU737092B2 (tr) |
| BR (1) | BR9812122A (tr) |
| CA (1) | CA2299471C (tr) |
| CZ (1) | CZ297198B6 (tr) |
| DE (1) | DE69802422T3 (tr) |
| DK (1) | DK1011648T4 (tr) |
| EA (1) | EA002525B1 (tr) |
| ES (1) | ES2163293T5 (tr) |
| HU (1) | HUP0003194A3 (tr) |
| NO (1) | NO325526B1 (tr) |
| NZ (2) | NZ502646A (tr) |
| PL (1) | PL193375B1 (tr) |
| PT (1) | PT1011648E (tr) |
| TR (1) | TR200000415T2 (tr) |
| UA (1) | UA61970C2 (tr) |
| WO (1) | WO1999008668A2 (tr) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000020034A1 (en) * | 1998-10-08 | 2000-04-13 | Takeda Chemical Industries, Ltd. | Agents for retarding change of hormone-dependent cancer into hormone-independent cancer |
| GB0007371D0 (en) * | 2000-03-28 | 2000-05-17 | Astrazeneca Uk Ltd | Chemical compounds |
| GB0008368D0 (en) * | 2000-04-06 | 2000-05-24 | Astrazeneca Ab | Combination product |
| US20020169154A1 (en) * | 2001-04-04 | 2002-11-14 | Cephalon, Inc. | Novel methods and compositions involving trk tyrosine kinase inhibitors and antineoplastic agents |
| SK14632003A3 (sk) * | 2001-05-08 | 2004-03-02 | Merck Patent Gmbh | Kombinovaná terapia pri použití anti-EGFR protilátok a antihormonálnych činidiel |
| SE0101697D0 (sv) * | 2001-05-14 | 2001-05-14 | Astrazeneca Ab | Pharmaceutical combination |
| IL144583A0 (en) | 2001-07-26 | 2002-05-23 | Peptor Ltd | Chimeric protein kinase inhibitors |
| EP1424080B1 (en) * | 2001-08-10 | 2011-02-16 | Takeda Pharmaceutical Company Limited | Gnrh agonist combination drugs |
| CN100488981C (zh) * | 2001-08-24 | 2009-05-20 | 维多利亚大学创新和发展公司 | 含有蛋白酶激活序列的气单胞菌溶素原及其应用 |
| US7425618B2 (en) | 2002-06-14 | 2008-09-16 | Medimmune, Inc. | Stabilized anti-respiratory syncytial virus (RSV) antibody formulations |
| US7132100B2 (en) | 2002-06-14 | 2006-11-07 | Medimmune, Inc. | Stabilized liquid anti-RSV antibody formulations |
| US7563810B2 (en) | 2002-11-06 | 2009-07-21 | Celgene Corporation | Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases |
| US8034831B2 (en) | 2002-11-06 | 2011-10-11 | Celgene Corporation | Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies |
| WO2004091510A2 (en) | 2003-04-11 | 2004-10-28 | Medimmune, Inc. | Recombinant il-9 antibodies and uses thereof |
| US20040224000A1 (en) * | 2003-05-05 | 2004-11-11 | Romano Deghenghi | Implants for non-radioactive brachytherapy of hormonal-insensitive cancers |
| IL156429A0 (en) * | 2003-06-12 | 2004-01-04 | Peptor Ltd | Cell permeable conjugates of peptides for inhibition of protein kinases |
| CA2536238C (en) | 2003-08-18 | 2015-04-07 | Medimmune, Inc. | Humanization of antibodies |
| CA2585717A1 (en) | 2004-10-27 | 2006-05-04 | Medimmune Inc. | Modulation of antibody specificity by tailoring the affinity to cognate antigens |
| EP1869192B1 (en) | 2005-03-18 | 2016-01-20 | MedImmune, LLC | Framework-shuffling of antibodies |
| CA2611839C (en) | 2005-06-14 | 2016-02-02 | Protox Therapeutics Incorporated | Method of treating or preventing benign prostatic hyperplasia using modified pore-forming proteins |
| KR20080025174A (ko) | 2005-06-23 | 2008-03-19 | 메디뮨 인코포레이티드 | 응집 및 단편화 프로파일이 최적화된 항체 제제 |
| WO2007092453A2 (en) * | 2006-02-03 | 2007-08-16 | Imclone Systems Incorporated | Igf-ir antagonists as adjuvants for treatment of prostate cancer |
| US20080021013A1 (en) * | 2006-07-21 | 2008-01-24 | Cephalon, Inc. | JAK inhibitors for treatment of myeloproliferative disorders |
| KR101314362B1 (ko) | 2006-08-28 | 2013-10-10 | 라 졸라 인스티튜트 포 앨러지 앤드 이뮤놀로지 | 길항성 인간 light-특이적 인간 모노클로날 항체 |
| US20100209434A1 (en) | 2007-03-30 | 2010-08-19 | Medimmune, Llc | Antibody formulation |
| US20090130195A1 (en) * | 2007-10-17 | 2009-05-21 | Mildred Acevedo-Duncan | Prostate carcinogenesis predictor |
| US12161734B2 (en) | 2009-07-02 | 2024-12-10 | Sloan-Kettering Institute For Cancer Research | Multimodal silica-based nanoparticles |
| US9540443B2 (en) | 2011-01-26 | 2017-01-10 | Kolltan Pharmaceuticals, Inc. | Anti-kit antibodies |
| NZ731881A (en) | 2012-07-25 | 2022-07-29 | Celldex Therapeutics Inc | Anti-kit antibodies and uses thereof |
| CA2887129A1 (en) | 2012-10-09 | 2014-04-17 | Igenica, Inc. | Anti-c16orf54 antibodies and methods of use thereof |
| JP6824735B2 (ja) | 2013-06-06 | 2021-02-03 | ピエール、ファーブル、メディカマン | 抗C10orf54抗体およびその使用方法 |
| AU2014332442B2 (en) | 2013-08-26 | 2019-12-19 | Biontech Research And Development, Inc. | Nucleic acids encoding human antibodies to Sialyl-Lewis |
| GB201403775D0 (en) | 2014-03-04 | 2014-04-16 | Kymab Ltd | Antibodies, uses & methods |
| KR102614642B1 (ko) | 2014-06-04 | 2023-12-19 | 바이오엔테크 리서치 앤드 디벨롭먼트 인코포레이티드 | 강글리오사이드 gd2에 대한 사람 단클론 항체 |
| SI3333191T1 (sl) | 2014-12-11 | 2021-03-31 | Pierre Fabre Medicament | Proti C10ORF54 protitelesa in uporaba le-teh |
| CN114504652A (zh) | 2015-03-03 | 2022-05-17 | 科马布有限公司 | 抗体、用途和方法 |
| US10736972B2 (en) * | 2015-05-29 | 2020-08-11 | Memorial Sloan Kettering Cancer Center | Methods of treatment using ultrasmall nanoparticles to induce cell death of nutrient-deprived cancer cells via ferroptosis |
| EP3383908A1 (en) | 2015-12-02 | 2018-10-10 | Stsciences, Inc. | Antibodies specific to glycosylated btla (b- and t- lymphocyte attenuator) |
| KR102803158B1 (ko) | 2015-12-02 | 2025-05-08 | 주식회사 에스티큐브앤컴퍼니 | Btn1a1에 면역특이적으로 결합하는 항체와 분자 및 그의 치료 용도 |
| US11779604B2 (en) | 2016-11-03 | 2023-10-10 | Kymab Limited | Antibodies, combinations comprising antibodies, biomarkers, uses and methods |
| BR112019024717A2 (pt) | 2017-05-25 | 2020-06-09 | Univ Cornell | nanopartículas ultrapequenas marcadas com zircônio-89 e métodos das mesmas |
| JP7369038B2 (ja) | 2017-05-31 | 2023-10-25 | ストキューブ アンド シーオー., インコーポレイテッド | Btn1a1に免疫特異的に結合する抗体及び分子並びにその治療的使用 |
| JP7768666B2 (ja) | 2017-05-31 | 2025-11-12 | ストキューブ アンド シーオー., インコーポレイテッド | Btn1a1に免疫特異的に結合する抗体及び分子を用いて癌を治療する方法 |
| CN121248782A (zh) | 2017-06-06 | 2026-01-02 | 斯特库伯株式会社 | 使用结合btn1a1或btn1a1-配体的抗体和分子治疗癌症的方法 |
| RU2667906C1 (ru) * | 2017-09-11 | 2018-09-25 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр онкологии имени Н.Н. Блохина" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ онкологии им. Н.Н. Блохина" Минздрава России) | Производное класса N-гликозидов индоло[2,3-а]пирроло[3,4-с]карбазол-5,7-дионов - N-{ 12-(β-D-ксилопиранозил)-5,7-диоксо-индоло[2,3-а]пирроло[3,4-с] карбазол-6-ил} пиридин-2-карбоксамид, обладающее цитотоксической и противоопухолевой активностью |
| CN111630069B (zh) | 2017-10-13 | 2024-05-31 | 勃林格殷格翰国际有限公司 | 针对Thomsen-nouvelle(Tn)抗原的人抗体 |
| IL280199B2 (en) | 2018-07-20 | 2025-08-01 | Pf Medicament | Receptor for vista |
| US12441707B2 (en) | 2019-12-30 | 2025-10-14 | Tyra Biosciences, Inc. | Indazole compounds |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4659695A (en) † | 1985-02-08 | 1987-04-21 | Fernand Labrie | Method of treatment of prostate cancer |
| US4923986A (en) † | 1987-03-09 | 1990-05-08 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of physiologically active substance K-252 |
| GB9300059D0 (en) * | 1992-01-20 | 1993-03-03 | Zeneca Ltd | Quinazoline derivatives |
| US5461146A (en) † | 1992-07-24 | 1995-10-24 | Cephalon, Inc. | Selected protein kinase inhibitors for the treatment of neurological disorders |
| DE69409641T2 (de) * | 1993-05-28 | 1998-11-26 | Cephalon, Inc., West Chester, Pa. | Anwendung von indolocarbazol-derivaten zur behandlung von prostataerkrankungen |
| WO1995024190A2 (en) * | 1994-03-07 | 1995-09-14 | Sugen, Inc. | Receptor tyrosine kinase inhibitors for inhibiting cell proliferative disorders and compositions thereof |
| SE506019C2 (sv) * | 1994-05-17 | 1997-11-03 | Forskarpatent I Linkoeping Ab | Ljuskälla av konjugerade polymerer med spänningsstyrd färg samt metod för tillverkning av ljuskällan |
| US5591855A (en) * | 1994-10-14 | 1997-01-07 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| US5705511A (en) * | 1994-10-14 | 1998-01-06 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| US5594009A (en) * | 1994-10-14 | 1997-01-14 | Cephalon, Inc. | Fused pyrrolocarbazoles |
| US5475110A (en) * | 1994-10-14 | 1995-12-12 | Cephalon, Inc. | Fused Pyrrolocarbazoles |
| US5650407A (en) * | 1995-04-05 | 1997-07-22 | Cephalon, Inc. | Selected soluble esters of hydroxyl-containing indolocarbazoles |
| GB9508538D0 (en) † | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
| US5659407A (en) * | 1995-06-06 | 1997-08-19 | Apple Computer, Inc. | Method and system for rendering achromatic image data for image output devices |
| KR20000065227A (ko) † | 1996-07-19 | 2000-11-06 | 다께다 구니오 | 복소환 화합물, 그의 제조방법 및 용도 |
-
1998
- 1998-08-13 AT AT98942057T patent/ATE208210T1/de not_active IP Right Cessation
- 1998-08-13 JP JP2000509408A patent/JP2001515032A/ja active Pending
- 1998-08-13 PT PT98942057T patent/PT1011648E/pt unknown
- 1998-08-13 NZ NZ502646A patent/NZ502646A/en unknown
- 1998-08-13 EA EA200000220A patent/EA002525B1/ru not_active IP Right Cessation
- 1998-08-13 TR TR2000/00415T patent/TR200000415T2/tr unknown
- 1998-08-13 AU AU90192/98A patent/AU737092B2/en not_active Ceased
- 1998-08-13 BR BR9812122-7A patent/BR9812122A/pt not_active IP Right Cessation
- 1998-08-13 US US09/133,567 patent/US5985877A/en not_active Expired - Fee Related
- 1998-08-13 CZ CZ20000469A patent/CZ297198B6/cs not_active IP Right Cessation
- 1998-08-13 CN CNB988081741A patent/CN1147317C/zh not_active Expired - Fee Related
- 1998-08-13 DK DK98942057T patent/DK1011648T4/da active
- 1998-08-13 WO PCT/US1998/016849 patent/WO1999008668A2/en not_active Ceased
- 1998-08-13 UA UA2000031438A patent/UA61970C2/uk unknown
- 1998-08-13 HU HU0003194A patent/HUP0003194A3/hu unknown
- 1998-08-13 DE DE69802422T patent/DE69802422T3/de not_active Expired - Lifetime
- 1998-08-13 EP EP98942057A patent/EP1011648B2/en not_active Expired - Lifetime
- 1998-08-13 NZ NZ517497A patent/NZ517497A/en unknown
- 1998-08-13 CA CA002299471A patent/CA2299471C/en not_active Expired - Fee Related
- 1998-08-13 PL PL98338885A patent/PL193375B1/pl not_active IP Right Cessation
- 1998-08-13 KR KR1020007001481A patent/KR100612161B1/ko not_active Expired - Fee Related
- 1998-08-13 ES ES98942057T patent/ES2163293T5/es not_active Expired - Lifetime
-
2000
- 2000-02-14 NO NO20000732A patent/NO325526B1/no not_active IP Right Cessation
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