DE60334289D1 - Dithiolopyrrolon-derivate zur behandlung von proliferativen störungen - Google Patents

Dithiolopyrrolon-derivate zur behandlung von proliferativen störungen

Info

Publication number
DE60334289D1
DE60334289D1 DE60334289T DE60334289T DE60334289D1 DE 60334289 D1 DE60334289 D1 DE 60334289D1 DE 60334289 T DE60334289 T DE 60334289T DE 60334289 T DE60334289 T DE 60334289T DE 60334289 D1 DE60334289 D1 DE 60334289D1
Authority
DE
Germany
Prior art keywords
treatment
proliferative disorder
dithiolopyrrolone
dithiolopyrrolone derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60334289T
Other languages
English (en)
Inventor
Genhui Chen
Bin Li
Jianxiong Li
John Webster
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welichem Biotech Inc
Original Assignee
Welichem Biotech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welichem Biotech Inc filed Critical Welichem Biotech Inc
Application granted granted Critical
Publication of DE60334289D1 publication Critical patent/DE60334289D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DE60334289T 2002-03-26 2003-03-18 Dithiolopyrrolon-derivate zur behandlung von proliferativen störungen Expired - Lifetime DE60334289D1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36726502P 2002-03-26 2002-03-26
US41869802P 2002-10-17 2002-10-17
PCT/CA2003/000380 WO2003080624A2 (en) 2002-03-26 2003-03-18 Dithiolopyrrolone derivatives useful in the treatment of proliferative diseases

Publications (1)

Publication Number Publication Date
DE60334289D1 true DE60334289D1 (de) 2010-11-04

Family

ID=28457151

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60334289T Expired - Lifetime DE60334289D1 (de) 2002-03-26 2003-03-18 Dithiolopyrrolon-derivate zur behandlung von proliferativen störungen

Country Status (10)

Country Link
US (1) US9051330B2 (de)
EP (1) EP1490374B1 (de)
JP (1) JP4530667B2 (de)
KR (1) KR100839214B1 (de)
CN (1) CN100347176C (de)
AT (1) ATE482217T1 (de)
CA (1) CA2479341C (de)
DE (1) DE60334289D1 (de)
HK (1) HK1074840A1 (de)
WO (1) WO2003080624A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2401077T3 (es) 2001-01-18 2013-04-16 Glaxo Group Limited Nuevos derivados 1,2-difenileteno para el tratamiento de enfermedades inmunológicas
CN101522688B (zh) * 2006-09-29 2011-09-14 北京文丰天济医药科技有限公司 二硫杂环戊烯并吡咯酮类新化合物及其治疗性应用
CN101381371B (zh) 2007-09-05 2011-05-18 上海医药工业研究院 二硫杂环戊烯并吡咯酮类化合物及其制备方法和应用
CN102219724B (zh) * 2010-05-17 2014-10-01 上海现代制药股份有限公司 吡咯酮类化合物及其制备方法和应用
CN102432624B (zh) * 2011-08-26 2013-12-18 魏爽 一种二硫杂环戊烯并吡咯酮类化合物结晶的制备工艺

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2752359A (en) * 1952-10-06 1956-06-26 Pfizer & Co C Antimicrobial agents
US2798811A (en) * 1953-07-23 1957-07-09 Schaefer Brewing Co Inhibiting micro-biological growth in beer
US2776967A (en) * 1955-09-08 1957-01-08 Upjohn Co Diketopregnanespirothiazolidine
US3038819A (en) * 1958-08-25 1962-06-12 Sidney H Ross Antibiotics as preservatives for industrial materials
US3057779A (en) * 1960-03-14 1962-10-09 American Cyanamid Co Antibiotic and production thereof
GB2173499A (en) * 1985-02-04 1986-10-15 Ici Plc Fungicidal dithiolopyrrolones
GB2170498A (en) 1985-02-04 1986-08-06 Ici Plc Processes for making fungicidal dithiolopyrrolones
JPS63112586A (ja) * 1986-10-29 1988-05-17 Nippon Kayaku Co Ltd ３−アシルアミノ−４−オキソ−４，５−ジヒドロ−１，２−ジチオロ〔４，３−ｂ〕ピロ−ル誘導体の製法
GB9310485D0 (en) * 1993-05-21 1993-07-07 Smithkline Beecham Plc Novel compounds
EP0712405A1 (de) 1993-08-13 1996-05-22 Smithkline Beecham Plc Derivate der monsäuren a und c mit antibakterieller, antimycloplasmatischer, fungizider und herbizider aktivität
US6583171B1 (en) * 1996-04-04 2003-06-24 Welichem Biotech Inc. Antineoplastic agents
US5827872A (en) * 1996-08-23 1998-10-27 Webster; John M. Xenomins novel heterocyclic compounds with antimicrobial and antneoplastic properties
US6020360A (en) * 1996-09-18 2000-02-01 Webster; John M. Anticancer property of dithiolopyrrolones
CA2212237A1 (en) 1997-09-05 1999-03-05 John M. Webster Novel antineoplastic agents
JP4960548B2 (ja) * 2000-01-07 2012-06-27 セケラ インコーポレイテッド 新規抗細菌化合物の用途
CN101522688B (zh) * 2006-09-29 2011-09-14 北京文丰天济医药科技有限公司 二硫杂环戊烯并吡咯酮类新化合物及其治疗性应用

Also Published As

Publication number Publication date
CN1642959A (zh) 2005-07-20
WO2003080624A2 (en) 2003-10-02
CN100347176C (zh) 2007-11-07
CA2479341C (en) 2012-07-10
HK1074840A1 (en) 2005-11-25
AU2003209899B2 (en) 2009-07-09
WO2003080624A3 (en) 2004-03-25
AU2003209899A1 (en) 2003-10-08
US20060074125A1 (en) 2006-04-06
JP4530667B2 (ja) 2010-08-25
JP2005526803A (ja) 2005-09-08
CA2479341A1 (en) 2003-10-02
ATE482217T1 (de) 2010-10-15
EP1490374B1 (de) 2010-09-22
US9051330B2 (en) 2015-06-09
KR100839214B1 (ko) 2008-06-17
EP1490374A2 (de) 2004-12-29
KR20050008666A (ko) 2005-01-21

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