ATE424208T1 - Proteinkinaseinhibitoren - Google Patents
ProteinkinaseinhibitorenInfo
- Publication number
- ATE424208T1 ATE424208T1 AT05744735T AT05744735T ATE424208T1 AT E424208 T1 ATE424208 T1 AT E424208T1 AT 05744735 T AT05744735 T AT 05744735T AT 05744735 T AT05744735 T AT 05744735T AT E424208 T1 ATE424208 T1 AT E424208T1
- Authority
- AT
- Austria
- Prior art keywords
- angiogenesis
- mammal
- relates
- compounds
- protein kinase
- Prior art date
Links
- 229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 title 1
- 239000003909 protein kinase inhibitor Substances 0.000 title 1
- 230000033115 angiogenesis Effects 0.000 abstract 5
- 241000124008 Mammalia Species 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 206010047050 Vascular anomaly Diseases 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 102000050554 Eph Family Receptors Human genes 0.000 abstract 1
- 108091008815 Eph receptors Proteins 0.000 abstract 1
- 102000001253 Protein Kinase Human genes 0.000 abstract 1
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
- 229940127361 Receptor Tyrosine Kinase Inhibitors Drugs 0.000 abstract 1
- 229940121369 angiogenesis inhibitor Drugs 0.000 abstract 1
- 239000004037 angiogenesis inhibitor Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 108060006633 protein kinase Proteins 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04013572 | 2004-06-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE424208T1 true ATE424208T1 (de) | 2009-03-15 |
Family
ID=34968638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05744735T ATE424208T1 (de) | 2004-06-09 | 2005-06-09 | Proteinkinaseinhibitoren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20070149535A1 (de) |
| EP (1) | EP1765351B9 (de) |
| AT (1) | ATE424208T1 (de) |
| AU (1) | AU2005251408A1 (de) |
| CA (1) | CA2570073A1 (de) |
| DE (1) | DE602005013085D1 (de) |
| ES (1) | ES2321315T3 (de) |
| WO (1) | WO2005120513A1 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7566716B2 (en) | 2005-05-20 | 2009-07-28 | Array Biopharma Inc. | Imidazopyrazines as Raf inhibitor compounds |
| US7893058B2 (en) | 2006-05-15 | 2011-02-22 | Janssen Pharmaceutica Nv | Imidazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
| HRP20100378T1 (hr) | 2006-05-31 | 2010-08-31 | Galapagos N.V. | Spojevi triazolopirazina učinkoviti za tretman degenerativnih i upalnih bolesti |
| JP2009539840A (ja) * | 2006-06-06 | 2009-11-19 | シェーリング コーポレイション | プロテインキナーゼ阻害剤としてのイミダゾピラジン |
| US8148369B2 (en) | 2007-05-10 | 2012-04-03 | Janssen Pharmaceutica Nv | Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
| WO2008141239A1 (en) * | 2007-05-10 | 2008-11-20 | Acadia Pharmaceuticals Inc. | Imidazol [1,2-a] pyridines and related compounds with activity at cannabinoid cb2 receptors |
| WO2010083617A1 (en) * | 2009-01-21 | 2010-07-29 | Oncalis Ag | Pyrazolopyrimidines as protein kinase inhibitors |
| PH12012500778A1 (en) | 2009-10-30 | 2012-11-26 | Janssen Pharmaceutica Nv | IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVES AND THEIR USE AS PDE10 INHIBITORS |
| AR080754A1 (es) | 2010-03-09 | 2012-05-09 | Janssen Pharmaceutica Nv | Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10 |
| JP6115962B2 (ja) | 2011-06-27 | 2017-04-19 | ヤンセン ファーマシューティカ エヌ．ベー． | １−アリール−４−メチル−［１，２，４］トリアゾロ［４，３−ａ］キノキサリン誘導体 |
| WO2014001314A1 (en) | 2012-06-26 | 2014-01-03 | Janssen Pharmaceutica Nv | Combinations comprising pde 2 inhibitors such as 1-aryl-4-methyl- [1,2,4] triazolo [4,3-a] quinoxaline compounds and pde 10 inhibitors for use in the treatment of neurological or metabolic disorders |
| AU2013289284B2 (en) | 2012-07-09 | 2017-03-30 | Janssen Pharmaceutica Nv | Inhibitors of phosphodiesterase 10 enzyme |
| US11718622B2 (en) | 2020-03-16 | 2023-08-08 | Exelixis Inc. | Heterocyclic adenosine receptor antagonists |
| EP4284798A1 (de) * | 2021-01-26 | 2023-12-06 | The USA, as represented by The Secretary, Department of Health and Human Services | Auf imidazo[1,2-a!pyrazin- und imidazo[1,2-a!pyridin basierende tyrosyl-dna phosphodiesterase i (tdp1) inhibitoren |
| US11970499B1 (en) | 2023-12-22 | 2024-04-30 | King Faisal University | Pyrazolo[1,5-c]pyrimidine compounds as CK2 inhibitors |
| US12129257B1 (en) | 2023-12-28 | 2024-10-29 | King Faisal University | Imidazo[1,2-a]pyrazine compounds as CK2 inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100756592B1 (ko) * | 1999-10-08 | 2007-09-10 | 그뤼넨탈 게엠베하 | 비사이클릭 이미다조-3-일-아민 유도체, 이의 제조방법 및 이를 포함하는 진통제 |
| GB0018473D0 (en) * | 2000-07-27 | 2000-09-13 | Merck Sharp & Dohme | Therapeutic agents |
| DE10050663A1 (de) * | 2000-10-13 | 2002-04-18 | Gruenenthal Gmbh | Verwendung von substituierten Imidazo[1,2-a]pyridin-, -pyrimidin- und pyrazin-3-yl-amin-Derivaten zur Herstellung von Medikamenten zur NOS-Inhibierung |
| DE10141212A1 (de) * | 2001-08-22 | 2003-03-06 | Bayer Ag | Neue 4-Aminofuropyrimidine und ihre Verwendung |
| US20030199525A1 (en) * | 2002-03-21 | 2003-10-23 | Hirst Gavin C. | Kinase inhibitors |
| BR0309398A (pt) * | 2002-04-19 | 2005-02-01 | Cellular Genomics Inc | Composto ou um seu sal, hidrato, solvato, forma cristalina, diastereÈmero, prodroga farmaceuticamente aceitável, ou misturas deles, composição farmacêutica, e, métodos para tratar uma condição envolvida com a cinase em um mamìfero, para tratar câncer, e para identificar uma cinase |
-
2005
- 2005-06-09 WO PCT/CH2005/000321 patent/WO2005120513A1/en not_active Ceased
- 2005-06-09 EP EP05744735A patent/EP1765351B9/de not_active Expired - Lifetime
- 2005-06-09 AT AT05744735T patent/ATE424208T1/de not_active IP Right Cessation
- 2005-06-09 AU AU2005251408A patent/AU2005251408A1/en not_active Abandoned
- 2005-06-09 ES ES05744735T patent/ES2321315T3/es not_active Expired - Lifetime
- 2005-06-09 DE DE602005013085T patent/DE602005013085D1/de not_active Expired - Lifetime
- 2005-06-09 CA CA002570073A patent/CA2570073A1/en not_active Abandoned
-
2006
- 2006-12-08 US US11/635,908 patent/US20070149535A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1765351B9 (de) | 2010-03-24 |
| ES2321315T3 (es) | 2009-06-04 |
| DE602005013085D1 (de) | 2009-04-16 |
| EP1765351B1 (de) | 2009-03-04 |
| US20070149535A1 (en) | 2007-06-28 |
| EP1765351A1 (de) | 2007-03-28 |
| AU2005251408A1 (en) | 2005-12-22 |
| WO2005120513A1 (en) | 2005-12-22 |
| CA2570073A1 (en) | 2005-12-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1765351 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |