ATE203162T1 - Verfahren zur behandlung von chronischer prostatitis mit 17-beta-n-tertbutylcarbamoyl-4- aza-5 alpha-androst-1-en-3-one - Google Patents

Verfahren zur behandlung von chronischer prostatitis mit 17-beta-n-tertbutylcarbamoyl-4- aza-5 alpha-androst-1-en-3-one

Info

Publication number
ATE203162T1
ATE203162T1 AT94901556T AT94901556T ATE203162T1 AT E203162 T1 ATE203162 T1 AT E203162T1 AT 94901556 T AT94901556 T AT 94901556T AT 94901556 T AT94901556 T AT 94901556T AT E203162 T1 ATE203162 T1 AT E203162T1
Authority
AT
Austria
Prior art keywords
alpha
androst
aza
beta
pct
Prior art date
Application number
AT94901556T
Other languages
English (en)
Inventor
Glenn J Gormley
Elizabeth Stoner
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE203162T1 publication Critical patent/ATE203162T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
AT94901556T 1992-12-18 1993-11-18 Verfahren zur behandlung von chronischer prostatitis mit 17-beta-n-tertbutylcarbamoyl-4- aza-5 alpha-androst-1-en-3-one ATE203162T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99298592A 1992-12-18 1992-12-18
PCT/US1993/011155 WO1994014452A1 (en) 1992-12-18 1993-11-18 METHOD OF TREATMENT OF CHRONIC PROSTATITIS WITH 17β-N-MONOSUBSTITUTED-CARBAMOYL-4-AZA-5α-ANDROST-1-EN-3-ONES

Publications (1)

Publication Number Publication Date
ATE203162T1 true ATE203162T1 (de) 2001-08-15

Family

ID=25538974

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94901556T ATE203162T1 (de) 1992-12-18 1993-11-18 Verfahren zur behandlung von chronischer prostatitis mit 17-beta-n-tertbutylcarbamoyl-4- aza-5 alpha-androst-1-en-3-one

Country Status (17)

Country Link
US (1) US5629318A (de)
EP (1) EP0674521B1 (de)
JP (1) JPH08504813A (de)
AT (1) ATE203162T1 (de)
AU (1) AU691164B2 (de)
CA (1) CA2151239A1 (de)
CZ (1) CZ285379B6 (de)
DE (1) DE69330465T2 (de)
DK (1) DK0674521T3 (de)
ES (1) ES2158887T3 (de)
FI (1) FI953002A0 (de)
GR (1) GR3036241T3 (de)
HU (1) HU220064B (de)
NO (1) NO308829B1 (de)
NZ (1) NZ258435A (de)
PT (1) PT674521E (de)
WO (1) WO1994014452A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999059583A1 (en) * 1998-05-18 1999-11-25 Merck & Co., Inc. Method for treating or preventing chronic nonbacterial prostatitis and prostatodynia
US6645974B2 (en) 2001-07-31 2003-11-11 Merck & Co., Inc. Androgen receptor modulators and methods for use thereof
US7101847B2 (en) * 2002-10-11 2006-09-05 Milkhaus Laboratory, Inc. Method of treating chronic pelvic pain syndrome by administration of chorionic gonadotropin
WO2005025572A1 (en) * 2003-09-10 2005-03-24 Merck & Co., Inc. 17-heterocyclic-4-azasteroid derivatives as androgen receptor modulators
CA2543956A1 (en) * 2003-10-31 2005-05-19 Merck & Co., Inc. 21-heterocyclic-4-azasteroid derivatives as androgen receptor modulators
US20080268463A1 (en) * 2007-03-07 2008-10-30 Children's Medical Center Corporation Methods for Prognosis and Diagnosis of Chronic Prostatitis/Pelvic Pain Syndrome and Interstitial Cystitis
RU2525182C1 (ru) * 2013-02-28 2014-08-10 Государственное бюджетное образовательное учреждение высшего профессионального образования Первый Московский государственный медицинский университет им. И.М. Сеченова Министерства здравоохранения Российской Федерации (ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздрава России) Способ лечения больных хроническим простатитом с парциальным андрогенодефицитом
CN104161739B (zh) * 2014-08-15 2017-09-19 武汉人福药业有限责任公司 非那雄胺胶囊及其制备方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2227876A (en) * 1937-10-16 1941-01-07 Firm Of N V Organon Steroid derivatives with nuclear substituted nitrogen
US3285918A (en) * 1962-04-18 1966-11-15 Norman J Doorenbos 1', 4', 5', 6'-tetrahydropyrimidino[a-4, 3]-4-aza-5-cholestene
US3239417A (en) * 1962-12-07 1966-03-08 Smith Kline French Lab Methods and compositions for inhibiting sterol biosynthesis
US3264301A (en) * 1963-08-22 1966-08-02 Norman J Doorenbos Substituted-4-azasteroids
FR1465544A (fr) * 1965-11-29 1967-01-13 Roussel Uclaf Dérivés stéroïdes aromatiques substitués par un atome d'azote endocyclique et procédé de préparation
US4377584A (en) * 1978-04-13 1983-03-22 Merck & Co., Inc. 4-Aza-17β-substituted-5α-androstan-3-one-reductase inhibitors
US4220775A (en) * 1979-03-15 1980-09-02 Merck & Co., Inc. Preparation of 4-aza-17-substituted-5α-androstan-3-ones useful as 5α-reductase inhibitors
US4859681A (en) * 1984-02-27 1989-08-22 Merck & Co., Inc. 17 α-Acyl-4-aza-5a-androst-1-en-3-ones as 5 alpha-reductase inhibitors
US4760071A (en) * 1984-02-27 1988-07-26 Merck & Co., Inc. 17β-N-monosubstituted carbamoyl-4-aza-5α-androst-1-en-3-ones which are active as testosterone 5α-reductase inhibitors
US5049562A (en) * 1984-02-27 1991-09-17 Merck & Co., Inc. 17β-acyl-4-aza-5α-androst-1-ene-3-ones as 5α-reductase inhibitors
US4845104A (en) * 1986-11-20 1989-07-04 Merck & Co., Inc. Oxidized analogs of 17β-N-monosubstituted-carbamoyl-4-aza-5-α-androstan-3-ones
DE3888378T2 (de) * 1987-04-03 1994-09-29 Merck & Co Inc Behandlung von Prostatacarcinoma mit 17-beta-n-monosubstituierten-Carbamoyl-4-aza-5-alpha-Androst-1-en-3-onen.
US4946688A (en) * 1988-07-05 1990-08-07 Fahim Mostafa S Intraprostatic injection of zinc ions for treatment of inflammatory conditions and benign and malignant tumors of the prostate
DK627289D0 (da) * 1989-12-12 1989-12-12 Per C Oden Anvendelse af bicyclononanderivater
US5175155A (en) * 1991-10-07 1992-12-29 Sterling Winthrop Inc. Win 49596-finasteride method of use and compositions
WO1993023420A1 (en) * 1992-05-20 1993-11-25 Merck & Co., Inc. NEW 7β-SUBSTITUTED-4-AZA-5α-ANDROSTAN-3-ONES AS 5α-REDUCTASE INHIBITORS
AU4251993A (en) * 1992-05-20 1993-12-13 Merck & Co., Inc. Substituted 4-aza-5A-androstan-ones as 5A-reductase inhibitors
GB9216284D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives
WO1994007861A1 (en) * 1992-10-06 1994-04-14 Merck & Co., Inc. 17β-CARBOXANILIDES OF 4-AZA-5α-ANDROSTAN-3-ONES AS 5α-REDUCTASE INHIBITORS

Also Published As

Publication number Publication date
PT674521E (pt) 2001-10-31
GR3036241T3 (en) 2001-10-31
NO952427D0 (no) 1995-06-16
CA2151239A1 (en) 1994-07-07
DK0674521T3 (da) 2001-09-24
ES2158887T3 (es) 2001-09-16
DE69330465D1 (de) 2001-08-23
EP0674521A1 (de) 1995-10-04
FI953002A (fi) 1995-06-16
AU691164B2 (en) 1998-05-14
FI953002A0 (fi) 1995-06-16
HU9501777D0 (en) 1995-08-28
EP0674521B1 (de) 2001-07-18
CZ157795A3 (en) 1995-11-15
US5629318A (en) 1997-05-13
JPH08504813A (ja) 1996-05-28
AU5610594A (en) 1994-07-19
HU220064B (hu) 2001-10-28
NZ258435A (en) 1997-05-26
DE69330465T2 (de) 2002-04-25
NO308829B1 (no) 2000-11-06
CZ285379B6 (cs) 1999-07-14
HUT73231A (en) 1996-07-29
WO1994014452A1 (en) 1994-07-07
NO952427L (no) 1995-06-16
EP0674521A4 (de) 1998-02-04

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee