DE69317578D1 - Verwendung von riluzole zur behandlung von traumatischen neurologischen-schädigungen - Google Patents

Verwendung von riluzole zur behandlung von traumatischen neurologischen-schädigungen

Info

Publication number
DE69317578D1
DE69317578D1 DE69317578T DE69317578T DE69317578D1 DE 69317578 D1 DE69317578 D1 DE 69317578D1 DE 69317578 T DE69317578 T DE 69317578T DE 69317578 T DE69317578 T DE 69317578T DE 69317578 D1 DE69317578 D1 DE 69317578D1
Authority
DE
Germany
Prior art keywords
riluzole
pct
treating traumatic
date
traumatic neurological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69317578T
Other languages
English (en)
Other versions
DE69317578T2 (de
Inventor
Adam Doble
Erik Louvel
Jeremy Pratt
Jean-Marie Stutzmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Application granted granted Critical
Publication of DE69317578D1 publication Critical patent/DE69317578D1/de
Publication of DE69317578T2 publication Critical patent/DE69317578T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
DE69317578T 1992-12-16 1993-12-10 Verwendung von riluzole zur behandlung von traumatischen neurologischen-schädigungen Expired - Lifetime DE69317578T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9215148A FR2699077B1 (fr) 1992-12-16 1992-12-16 Application d'anticonvulsivants dans le traitement de lésions neurologiques liées à des traumatismes.
PCT/FR1993/001229 WO1994013288A1 (fr) 1992-12-16 1993-12-10 Application du riluzole dans le traitement de lesions neurologiques liees a des traumatismes

Publications (2)

Publication Number Publication Date
DE69317578D1 true DE69317578D1 (de) 1998-04-23
DE69317578T2 DE69317578T2 (de) 1998-07-23

Family

ID=9436652

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69317578T Expired - Lifetime DE69317578T2 (de) 1992-12-16 1993-12-10 Verwendung von riluzole zur behandlung von traumatischen neurologischen-schädigungen

Country Status (23)

Country Link
US (1) US5830907A (de)
EP (3) EP0674518A1 (de)
JP (3) JPH08504429A (de)
KR (3) KR950703965A (de)
AT (1) ATE164067T1 (de)
AU (3) AU5653994A (de)
CA (3) CA2151604C (de)
CZ (3) CZ284420B6 (de)
DE (1) DE69317578T2 (de)
DK (1) DK0674512T3 (de)
ES (1) ES2113635T3 (de)
FR (1) FR2699077B1 (de)
GR (1) GR3026403T3 (de)
HU (3) HU217133B (de)
IL (3) IL108051A (de)
MX (3) MX9307884A (de)
NO (3) NO952228L (de)
PL (3) PL309348A1 (de)
RU (1) RU2142800C1 (de)
SK (3) SK78595A3 (de)
UA (1) UA41906C2 (de)
WO (3) WO1994013288A1 (de)
ZA (3) ZA939401B (de)

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US9765020B2 (en) 2012-05-23 2017-09-19 Cellix Bio Private Limited Dichlorophenyl-imino compounds and compositions, and methods for the treatment of mucositis
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US9187427B2 (en) 2012-08-03 2015-11-17 Cellix Bio Private Limited N-substituted nicotinamide compounds and compositions for the treatment migraine and neurologic diseases
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US9321716B1 (en) 2014-11-05 2016-04-26 Cellix Bio Private Limited Compositions and methods for the treatment of metabolic syndrome
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EP3242869B1 (de) 2015-01-06 2021-10-27 Cellixbio Private Limited Zusammensetzungen und verfahren zur behandlung von entzündungen und schmerzen
EP3353145B1 (de) 2015-09-23 2022-09-28 XWPharma Ltd. Prodrugs von gamma-hydroxybuttersäure, zusammensetzungen und verwendungen davon
CA3058216C (en) 2017-03-30 2023-08-15 Xw Laboratories Inc. Bicyclic heteroaryl derivatives and preparation and uses thereof
US10322114B2 (en) 2017-07-31 2019-06-18 Above And Beyond Nb, Llc Formulation of a riluzole solution with beta-cyclodextrins
US20200289476A1 (en) * 2017-11-28 2020-09-17 University Of Houston System Liquid formulations of riluzole for oral and intravenous use
JP6996029B2 (ja) 2018-09-30 2022-01-17 エックスダブリューファルマ リミテッド ニューロンヒスタミン受容体-3アンタゴニストとしての化合物およびその使用
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Also Published As

Publication number Publication date
CA2151604A1 (fr) 1994-06-23
SK78795A3 (en) 1996-05-08
EP0674518A1 (de) 1995-10-04
NO952229L (no) 1995-06-06
CA2151604C (fr) 2005-09-20
RU2142800C1 (ru) 1999-12-20
HUT71812A (en) 1996-02-28
HU9501753D0 (en) 1995-08-28
CZ154795A3 (en) 1995-11-15
AU5654094A (en) 1994-07-04
CA2151601A1 (fr) 1994-06-23
JP3712239B2 (ja) 2005-11-02
KR950703965A (ko) 1995-11-17
SK78595A3 (en) 1996-05-08
UA41906C2 (uk) 2001-10-15
ZA939399B (en) 1994-08-22
SK279759B6 (sk) 1999-03-12
JPH08504428A (ja) 1996-05-14
PL309348A1 (en) 1995-10-02
NO952228D0 (no) 1995-06-06
JPH08504430A (ja) 1996-05-14
US5830907A (en) 1998-11-03
FR2699077A1 (fr) 1994-06-17
KR100298808B1 (ko) 2001-11-22
SK78695A3 (en) 1996-05-08
EP0674512A1 (de) 1995-10-04
NO307027B1 (no) 2000-01-31
AU678795B2 (en) 1997-06-12
WO1994013288A1 (fr) 1994-06-23
DE69317578T2 (de) 1998-07-23
CZ284420B6 (cs) 1998-11-11
GR3026403T3 (en) 1998-06-30
MX9307883A (es) 1994-06-30
IL108051A (en) 1999-05-09
IL108052A0 (en) 1994-04-12
PL309346A1 (en) 1995-10-02
HU217133B (hu) 1999-11-29
FR2699077B1 (fr) 1995-01-13
EP0674512B1 (de) 1998-03-18
NO952228L (no) 1995-06-06
IL108053A0 (en) 1994-04-12
WO1994013296A1 (fr) 1994-06-23
ATE164067T1 (de) 1998-04-15
ZA939400B (en) 1994-08-19
NO952230L (no) 1995-06-06
ES2113635T3 (es) 1998-05-01
MX9307882A (es) 1994-06-30
HUT71814A (en) 1996-02-28
KR950703954A (ko) 1995-11-17
ZA939401B (en) 1994-08-19
HUT71839A (en) 1996-02-28
PL309347A1 (en) 1995-10-02
IL108051A0 (en) 1994-04-12
CZ154695A3 (en) 1995-11-15
NO952229D0 (no) 1995-06-06
AU5702094A (en) 1994-07-04
MX9307884A (es) 1994-06-30
EP0674520A1 (de) 1995-10-04
CA2151603A1 (fr) 1994-06-23
HU9501752D0 (en) 1995-08-28
DK0674512T3 (da) 1998-05-25
AU5653994A (en) 1994-07-04
WO1994013298A1 (fr) 1994-06-23
KR950703968A (ko) 1995-11-17
CZ154595A3 (en) 1995-11-15
JPH08504429A (ja) 1996-05-14
HU9501751D0 (en) 1995-08-28
NO952230D0 (no) 1995-06-06

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Legal Events

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8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS PHARMA S.A., ANTONY, FR

8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC