UA116444C2 - Штам, який походить зі штаму lactobacillus sp. та продукує d-молочну кислоту, спосіб його одержання та спосіб продукування d-молочної кислоти - Google Patents

Штам, який походить зі штаму lactobacillus sp. та продукує d-молочну кислоту, спосіб його одержання та спосіб продукування d-молочної кислоти

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UA116444C2
UA116444C2 UAA201411896A UAA201411896A UA116444C2 UA 116444 C2 UA116444 C2 UA 116444C2 UA A201411896 A UAA201411896 A UA A201411896A UA A201411896 A UAA201411896 A UA A201411896A UA 116444 C2 UA116444 C2 UA 116444C2
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lactic acid
producing
strain
producibility
strain producing
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UAA201411896A
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English (en)
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Ин Пін Ян
Те Хі Лі
Сеон Хе Кім
Юн Льол Ян
Хун Сянь Лі
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Чх-Ч Чхейлчетан Корпорейшн
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Publication of UA116444C2 publication Critical patent/UA116444C2/uk

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    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01027—L-Lactate dehydrogenase (1.1.1.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01028—D-Lactate dehydrogenase (1.1.1.28)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
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  • Microbiology (AREA)
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  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Винахід стосується штаму, який продукує D-молочну кислоту, що походить зі штаму Lactobacillus sp., модифікований для інактивації активності L-лактатдегідрогенази (L-LDH) та посилення активності D-лактатдегідрогенази (D-LDH) у Lactobacillus sp. штамі, що продукує більше L-молочної кислоти, ніж D-молочної кислоти, і в якому вказаний штам Lactobacillus sp. вибрано з групи, що складається з Lactobacillus casei, Lactobacillus paracasei та Lactobacillus rhamnosus. Також винахід стосується способу одержання штаму, який продукує D-молочну кислоту, та способу продукування D-молочної кислоти, який включає стадії культивування штаму та виділення D-молочної кислоти з культурального середовища.
UAA201411896A 2012-04-24 2013-04-24 Штам, який походить зі штаму lactobacillus sp. та продукує d-молочну кислоту, спосіб його одержання та спосіб продукування d-молочної кислоти UA116444C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20120042894A KR101438882B1 (ko) 2012-04-24 2012-04-24 신규한 ｄ형 젖산 생산균주
PCT/KR2013/003501 WO2013162274A1 (ko) 2012-04-24 2013-04-24 신규한 ｄ형 젖산 생산균주 및 그의 용도

Publications (1)

Publication Number Publication Date
UA116444C2 true UA116444C2 (uk) 2018-03-26

Family

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UAA201411896A UA116444C2 (uk) 2012-04-24 2013-04-24 Штам, який походить зі штаму lactobacillus sp. та продукує d-молочну кислоту, спосіб його одержання та спосіб продукування d-молочної кислоти

Country Status (13)

Country Link
US (1) US10138500B2 (uk)
EP (1) EP2843039B1 (uk)
JP (2) JP6085023B2 (uk)
KR (1) KR101438882B1 (uk)
CN (1) CN104395456A (uk)
AU (1) AU2013253153B2 (uk)
BR (1) BR112014026720B1 (uk)
MY (1) MY182333A (uk)
PL (1) PL2843039T3 (uk)
RU (1) RU2639507C2 (uk)
SG (2) SG11201406876VA (uk)
UA (1) UA116444C2 (uk)
WO (1) WO2013162274A1 (uk)

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KR101438882B1 (ko) * 2012-04-24 2014-09-05 씨제이제일제당 (주) 신규한 ｄ형 젖산 생산균주
KR102214835B1 (ko) * 2014-09-19 2021-02-10 삼성전자주식회사 락테이트 데히드로게나제 변이체, 상기 변이체를 코딩하는 폴리뉴클레오티드, 상기 폴리뉴클레오티드를 포함하는 효모 세포, 및 이를 이용한 락테이트의 생산 방법
KR102144997B1 (ko) * 2014-02-14 2020-08-14 삼성전자주식회사 락테이트 데히드로게나제 변이체, 상기 변이체를 코딩하는 폴리뉴클레오티드, 상기 폴리뉴클레오티드를 포함하는 효모 세포, 상기 변이체의 제조 방법 및 이를 이용한 락테이트의 생산 방법
KR101577134B1 (ko) * 2014-05-09 2015-12-14 씨제이제일제당 (주) 젖산 생산이 향상된 미생물 및 이를 이용하여 젖산을 생산하는 방법
CA2955717C (en) * 2014-07-23 2020-09-22 Purac Biochem Bv Genetically modified (r)-lactic acid producing thermophilic bacteria
KR101719035B1 (ko) * 2014-09-19 2017-03-23 포항공과대학교 산학협력단 신규 효소를 사용한 d형 젖산의 제조
KR102581464B1 (ko) * 2015-05-28 2023-09-21 삼성전자주식회사 락테이트 데히드로게나제 변이체를 스크리닝하는 방법, 락테이트 데히드로게나제 변이체, 상기 변이체를 포함하는 폴리뉴클레오티드, 벡터, 미생물, 및 상기 미생물을 이용하여 락테이트를 생산하는 방법
CN107922917A (zh) * 2015-06-12 2018-04-17 Cj第制糖株式会社 乳酸生产率提高的微生物和使用其生产乳酸的方法
MY182357A (en) * 2015-10-16 2021-01-20 Iner Aec Executive Yuan Highly optically pure l-lactic acid-producing strain with tolerance to lignocellulosic hydrolysate
CN107267476B (zh) * 2016-04-08 2019-08-30 中国科学院微生物研究所 一种乳酸脱氢酶及其在制备乳酸中应用
CN109385389A (zh) * 2017-08-08 2019-02-26 光明乳业股份有限公司 一种缺失ldhA基因的植物乳杆菌ST-Ⅲ及其制备方法
KR101915463B1 (ko) 2018-05-02 2018-11-06 (주)잇츠한불 신규한 락토바실러스 펜토서스 균주 및 이를 포함하는 프로바이오틱스 제제 또는 조성물
CN109504630B (zh) * 2018-12-17 2022-03-11 吉林中粮生化有限公司 一种重组d-乳酸生产植物乳杆菌菌株及利用该菌株生产d-乳酸的方法
JP2021007309A (ja) * 2019-06-28 2021-01-28 裕希 土肥 形質転換体およびそれを用いたｄ−乳酸の生産方法
CN111500517B (zh) * 2020-05-27 2020-12-11 吉林中粮生化有限公司 产l-乳酸的重组菌株及其构建方法和发酵产l-乳酸的方法及应用
CN111378698B (zh) * 2020-06-01 2020-12-25 中粮营养健康研究院有限公司 发酵制备d-乳酸的方法
CN111849852A (zh) * 2020-06-01 2020-10-30 华东理工大学 一种高光学纯l-乳酸工程菌的构建方法

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Publication number Publication date
EP2843039A1 (en) 2015-03-04
MY182333A (en) 2021-01-19
SG11201406876VA (en) 2015-01-29
KR101438882B1 (ko) 2014-09-05
AU2013253153B2 (en) 2017-06-08
CN104395456A (zh) 2015-03-04
BR112014026720B1 (pt) 2023-02-23
RU2014144647A (ru) 2016-06-10
SG10201803888UA (en) 2018-06-28
AU2013253153A1 (en) 2014-11-20
JP6085023B2 (ja) 2017-02-22
WO2013162274A1 (ko) 2013-10-31
US20150118724A1 (en) 2015-04-30
RU2639507C2 (ru) 2017-12-21
US10138500B2 (en) 2018-11-27
BR112014026720A2 (pt) 2017-06-27
EP2843039B1 (en) 2020-11-04
KR20130126809A (ko) 2013-11-21
PL2843039T3 (pl) 2021-07-05
JP2015514434A (ja) 2015-05-21
JP2017070288A (ja) 2017-04-13
EP2843039A4 (en) 2016-01-06

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