SG10201803888UA - Novel d-lactic acid-producing strain and use thereof - Google Patents

Novel d-lactic acid-producing strain and use thereof

Info

Publication number
SG10201803888UA
SG10201803888UA SG10201803888UA SG10201803888UA SG10201803888UA SG 10201803888U A SG10201803888U A SG 10201803888UA SG 10201803888U A SG10201803888U A SG 10201803888UA SG 10201803888U A SG10201803888U A SG 10201803888UA SG 10201803888U A SG10201803888U A SG 10201803888UA
Authority
SG
Singapore
Prior art keywords
lactic acid
producing strain
novel
producing
strain
Prior art date
Application number
SG10201803888UA
Inventor
Eun Bin Yang
Tae Hee Lee
Seon Hye Kim
Young Lyeol Yang
Hong Xian Li
Original Assignee
Cj Cheiljedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corp filed Critical Cj Cheiljedang Corp
Publication of SG10201803888UA publication Critical patent/SG10201803888UA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01027—L-Lactate dehydrogenase (1.1.1.27)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01028—D-Lactate dehydrogenase (1.1.1.28)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

OF THE DISCLOSURE The present invention relates to a method for preparing a D-lactic acid-producing strain modified to inhibit L- lactate dehydrogenase (L-LDH) activity and to introduce D- lactate dehydrogenase (D-LDH) activity in an L-lactic acid- producing strain, a mutated D-lactic acid-producing strain prepared by the above method, and a method for producing D- lactic acid including the steps of culturing the strain and recovering D-lactic acid from the culture media. Figure 44
SG10201803888UA 2012-04-24 2013-04-24 Novel d-lactic acid-producing strain and use thereof SG10201803888UA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR20120042894A KR101438882B1 (en) 2012-04-24 2012-04-24 Novel microorganism for producing D-type lactic acid

Publications (1)

Publication Number Publication Date
SG10201803888UA true SG10201803888UA (en) 2018-06-28

Family

ID=49483496

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201803888UA SG10201803888UA (en) 2012-04-24 2013-04-24 Novel d-lactic acid-producing strain and use thereof
SG11201406876VA SG11201406876VA (en) 2012-04-24 2013-04-24 Novel d-lactic acid-producing strain and use thereof

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201406876VA SG11201406876VA (en) 2012-04-24 2013-04-24 Novel d-lactic acid-producing strain and use thereof

Country Status (13)

Country Link
US (1) US10138500B2 (en)
EP (1) EP2843039B1 (en)
JP (2) JP6085023B2 (en)
KR (1) KR101438882B1 (en)
CN (1) CN104395456A (en)
AU (1) AU2013253153B2 (en)
BR (1) BR112014026720B1 (en)
MY (1) MY182333A (en)
PL (1) PL2843039T3 (en)
RU (1) RU2639507C2 (en)
SG (2) SG10201803888UA (en)
UA (1) UA116444C2 (en)
WO (1) WO2013162274A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101438882B1 (en) 2012-04-24 2014-09-05 씨제이제일제당 (주) Novel microorganism for producing D-type lactic acid
KR102144997B1 (en) * 2014-02-14 2020-08-14 삼성전자주식회사 Lactate dehydrogenase mutant, polynucleotide coding the mutant, yeast cell having the polynucleotide, method of the mutant, and method of producing the lactate using the same
KR102214835B1 (en) * 2014-09-19 2021-02-10 삼성전자주식회사 Lactate dehydrogenase mutant, polynucleotide coding the mutant, yeast cell having the polynucleotide, and method for producing the lactate using the same
KR101577134B1 (en) * 2014-05-09 2015-12-14 씨제이제일제당 (주) A microorganism having enhanced productivity of lactic acid and a process for producing lactic acid using the same
PL3194592T3 (en) * 2014-07-23 2021-02-08 Purac Biochem Bv Genetically modified (r)-lactic acid producing thermophilic bacteria
KR101719035B1 (en) * 2014-09-19 2017-03-23 포항공과대학교 산학협력단 Preparation of d-lactic acid using new enzymes
KR102581464B1 (en) * 2015-05-28 2023-09-21 삼성전자주식회사 Method for screeninig a lactate dehydrogenase mutant, lactate dehydrogenase mutant, polynucleotide, vector, microorganism including the mutant, and method for preparing a lactate using the microorganism
CN107922917A (en) * 2015-06-12 2018-04-17 Cj第制糖株式会社 The microorganism and produce the method for lactic acid using it that production of lactic acid rate improves
MY182357A (en) * 2015-10-16 2021-01-20 Iner Aec Executive Yuan Highly optically pure l-lactic acid-producing strain with tolerance to lignocellulosic hydrolysate
CN107267476B (en) * 2016-04-08 2019-08-30 中国科学院微生物研究所 It a kind of lactic dehydrogenase and its is applied in preparing lactic acid
CN109385389A (en) * 2017-08-08 2019-02-26 光明乳业股份有限公司 A kind of lactobacillus plantarum ST-III and preparation method thereof lacking ldhA gene
KR101915463B1 (en) 2018-05-02 2018-11-06 (주)잇츠한불 Novel lactobacillus pentosus, and probiotics and composition containing the same
CN109504630B (en) * 2018-12-17 2022-03-11 吉林中粮生化有限公司 Lactobacillus plantarum strain produced by recombinant D-lactic acid and method for producing D-lactic acid by using strain
JP2021007309A (en) * 2019-06-28 2021-01-28 裕希 土肥 Transformant and method for producing d-lactic acid using the same
CN111500517B (en) * 2020-05-27 2020-12-11 吉林中粮生化有限公司 Recombinant strain for producing L-lactic acid, construction method thereof, method for producing L-lactic acid by fermentation and application thereof
CN111378698B (en) * 2020-06-01 2020-12-25 中粮营养健康研究院有限公司 Method for preparing D-lactic acid by fermentation
CN111849852A (en) * 2020-06-01 2020-10-30 华东理工大学 Construction method of high-optical-purity L-lactic acid engineering bacteria

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2931939B2 (en) 1992-07-10 1999-08-09 明治乳業株式会社 Lactobacillus delbrueckii Method for Gene Integration into Species Chromosome and Gene Integrant
PH31093A (en) * 1993-08-06 1998-02-05 Nestec Ltd Lactobacillus bulgaricus having decreased acid production and/or improved aroma and flavor production and food composition comprising said lactobacillus.
DK0875579T3 (en) * 1997-05-03 2007-10-22 Nestle Sa Preparation of L (+) lactate
ATE367436T1 (en) 2002-05-30 2007-08-15 Natureworks Llc METHOD AND MATERIALS FOR PRODUCING D-LACTIC ACID IN YEAST
CN1245515C (en) * 2004-03-03 2006-03-15 南开大学 Gene of L-lactate dehydrogenase, recombined carrier containing said gene and host-cell thereof
US20060025190A1 (en) 2004-07-28 2006-02-02 Kraft David W System and method of gaming involving continued distribution of components until certain criteria are met
DE102007047206B4 (en) * 2007-10-02 2016-08-11 Insilico Biotechnology Ag Biotechnological fixation of carbon dioxide
CN101993850B (en) * 2010-08-08 2012-11-14 天津大学 Genetic engineering bacteria for producing D-lactic acid and constructon method and application thereof
KR101438882B1 (en) 2012-04-24 2014-09-05 씨제이제일제당 (주) Novel microorganism for producing D-type lactic acid

Also Published As

Publication number Publication date
US10138500B2 (en) 2018-11-27
RU2639507C2 (en) 2017-12-21
JP6085023B2 (en) 2017-02-22
RU2014144647A (en) 2016-06-10
MY182333A (en) 2021-01-19
WO2013162274A1 (en) 2013-10-31
JP2015514434A (en) 2015-05-21
EP2843039B1 (en) 2020-11-04
AU2013253153B2 (en) 2017-06-08
BR112014026720A2 (en) 2017-06-27
CN104395456A (en) 2015-03-04
KR20130126809A (en) 2013-11-21
PL2843039T3 (en) 2021-07-05
SG11201406876VA (en) 2015-01-29
EP2843039A4 (en) 2016-01-06
AU2013253153A1 (en) 2014-11-20
KR101438882B1 (en) 2014-09-05
UA116444C2 (en) 2018-03-26
JP2017070288A (en) 2017-04-13
BR112014026720B1 (en) 2023-02-23
EP2843039A1 (en) 2015-03-04
US20150118724A1 (en) 2015-04-30

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