UA103332C2 - Фармацевтическая композиция, которая содержит непептидный активный агент с первичной или вторичной аминогруппой - Google Patents

Фармацевтическая композиция, которая содержит непептидный активный агент с первичной или вторичной аминогруппой

Info

Publication number
UA103332C2
UA103332C2 UAA201102390A UAA201102390A UA103332C2 UA 103332 C2 UA103332 C2 UA 103332C2 UA A201102390 A UAA201102390 A UA A201102390A UA A201102390 A UAA201102390 A UA A201102390A UA 103332 C2 UA103332 C2 UA 103332C2
Authority
UA
Ukraine
Prior art keywords
pharmaceutical composition
primary
nonpeptidic
amino group
secondary amino
Prior art date
Application number
UAA201102390A
Other languages
English (en)
Ukrainian (uk)
Inventor
Ясухиро Хираиши
Мунео Нономура
Original Assignee
Такеда Фармасьютикал Компани Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41327301&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA103332(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Такеда Фармасьютикал Компани Лимитед filed Critical Такеда Фармасьютикал Компани Лимитед
Publication of UA103332C2 publication Critical patent/UA103332C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Данное изобретение касается фармацевтической композиции или твердой лекарственной формы, которая содержит стабилизированный непептидный фармацевтически активный ингредиент с первичной или вторичной аминогруппой, наполнитель и кислоту как стабилизатор, и способа ее стабилизации.
UAA201102390A 2008-07-28 2009-07-27 Фармацевтическая композиция, которая содержит непептидный активный агент с первичной или вторичной аминогруппой UA103332C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008194219 2008-07-28
PCT/JP2009/063708 WO2010013823A2 (en) 2008-07-28 2009-07-27 Pharmaceutical composition

Publications (1)

Publication Number Publication Date
UA103332C2 true UA103332C2 (ru) 2013-10-10

Family

ID=41327301

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201102390A UA103332C2 (ru) 2008-07-28 2009-07-27 Фармацевтическая композиция, которая содержит непептидный активный агент с первичной или вторичной аминогруппой

Country Status (29)

Country Link
US (2) US9186411B2 (ru)
EP (2) EP2564833B1 (ru)
JP (2) JP5295356B2 (ru)
KR (1) KR20110042334A (ru)
CN (3) CN102164581A (ru)
AR (1) AR072842A1 (ru)
AU (1) AU2009277443A1 (ru)
BR (1) BRPI0916689A2 (ru)
CA (2) CA2732243C (ru)
CL (1) CL2011000170A1 (ru)
CO (1) CO6290638A2 (ru)
CR (1) CR20110110A (ru)
DO (2) DOP2011000033A (ru)
EA (2) EA201170272A1 (ru)
EC (1) ECSP11010855A (ru)
ES (2) ES2669592T3 (ru)
GE (2) GEP20146166B (ru)
IL (2) IL210735A0 (ru)
MA (1) MA32556B1 (ru)
MX (1) MX2011000757A (ru)
MY (2) MY169461A (ru)
NZ (2) NZ602592A (ru)
PE (3) PE20110591A1 (ru)
SG (1) SG186685A1 (ru)
TW (2) TW201431552A (ru)
UA (1) UA103332C2 (ru)
UY (1) UY32008A (ru)
WO (1) WO2010013823A2 (ru)
ZA (1) ZA201101198B (ru)

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Also Published As

Publication number Publication date
MY156305A (en) 2016-01-29
BRPI0916689A2 (pt) 2015-11-17
CA2732243A1 (en) 2010-02-04
MX2011000757A (es) 2011-02-24
ECSP11010855A (es) 2011-03-31
NZ602592A (en) 2014-01-31
EP2309985A2 (en) 2011-04-20
JP2013047239A (ja) 2013-03-07
UY32008A (es) 2010-02-26
IL228817A0 (en) 2013-12-31
TW201431552A (zh) 2014-08-16
JP5593363B2 (ja) 2014-09-24
ZA201101198B (en) 2012-05-30
EA201201451A1 (ru) 2013-07-30
PE20110591A1 (es) 2011-09-15
CA2732243C (en) 2016-11-29
EP2564833A1 (en) 2013-03-06
CN102164581A (zh) 2011-08-24
MA32556B1 (fr) 2011-08-01
US20130261156A1 (en) 2013-10-03
CO6290638A2 (es) 2011-06-20
PE20140977A1 (es) 2014-08-20
CA2936400C (en) 2018-03-27
CR20110110A (es) 2011-04-28
KR20110042334A (ko) 2011-04-26
IL210735A0 (en) 2011-03-31
EP2564833B1 (en) 2017-12-20
PE20141585A1 (es) 2014-11-13
US20110124687A1 (en) 2011-05-26
GEP20146166B (en) 2014-09-25
US9186411B2 (en) 2015-11-17
MY169461A (en) 2019-04-11
WO2010013823A3 (en) 2010-04-15
ES2669592T3 (es) 2018-05-28
ES2660962T3 (es) 2018-03-26
CN104784180A (zh) 2015-07-22
JP2011529445A (ja) 2011-12-08
GEP20146122B (en) 2014-07-25
AU2009277443A1 (en) 2010-02-04
EP2309985B1 (en) 2018-03-14
JP5295356B2 (ja) 2013-09-18
SG186685A1 (en) 2013-01-30
CN102743330B (zh) 2016-03-23
DOP2013000172A (es) 2013-11-15
CA2936400A1 (en) 2010-02-04
CN102743330A (zh) 2012-10-24
EA201170272A1 (ru) 2011-10-31
WO2010013823A2 (en) 2010-02-04
DOP2011000033A (es) 2011-04-15
AR072842A1 (es) 2010-09-22
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