TW319698B - - Google Patents

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Publication number
TW319698B
TW319698B TW082110824A TW82110824A TW319698B TW 319698 B TW319698 B TW 319698B TW 082110824 A TW082110824 A TW 082110824A TW 82110824 A TW82110824 A TW 82110824A TW 319698 B TW319698 B TW 319698B
Authority
TW
Taiwan
Prior art keywords
lower alkyl
group
inhibitor
alkoxy
scope
Prior art date
Application number
TW082110824A
Other languages
English (en)
Chinese (zh)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of TW319698B publication Critical patent/TW319698B/zh

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
TW082110824A 1992-12-23 1993-12-21 TW319698B (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US99548892A 1992-12-23 1992-12-23

Publications (1)

Publication Number Publication Date
TW319698B true TW319698B (enExample) 1997-11-11

Family

ID=25541876

Family Applications (1)

Application Number Title Priority Date Filing Date
TW082110824A TW319698B (enExample) 1992-12-23 1993-12-21

Country Status (32)

Country Link
US (1) US5661145A (enExample)
EP (1) EP0675714B1 (enExample)
JP (1) JP3992728B2 (enExample)
KR (1) KR100306936B1 (enExample)
CN (1) CN1090479C (enExample)
AT (1) ATE175872T1 (enExample)
AU (1) AU680864B2 (enExample)
CA (1) CA2152351C (enExample)
CZ (1) CZ287125B6 (enExample)
DE (1) DE69323213T2 (enExample)
DK (1) DK0675714T3 (enExample)
EE (1) EE03383B1 (enExample)
ES (1) ES2128552T3 (enExample)
FI (1) FI952916A7 (enExample)
GR (1) GR3029405T3 (enExample)
HR (1) HRP931515B1 (enExample)
HU (1) HU221724B1 (enExample)
IL (1) IL108112A (enExample)
LT (1) LT3300B (enExample)
LV (1) LV10919B (enExample)
MX (1) MX9308053A (enExample)
MY (1) MY109538A (enExample)
NO (1) NO311325B1 (enExample)
NZ (1) NZ259790A (enExample)
PL (1) PL174128B1 (enExample)
SG (1) SG45147A1 (enExample)
SI (1) SI9300677A (enExample)
SK (1) SK281173B6 (enExample)
TW (1) TW319698B (enExample)
WO (1) WO1994014433A1 (enExample)
YU (1) YU49060B (enExample)
ZA (1) ZA939552B (enExample)

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US6593078B1 (en) 1999-04-16 2003-07-15 Schering Corporation Use of azetidinone compounds
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US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
CN101297969B (zh) * 2001-01-26 2011-03-09 先灵公司 过氧化物酶体增殖物激活受体(ppar)活化剂和甾醇吸收抑制剂的组合药
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US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
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US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
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CA2504878A1 (en) 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorption inhibitors for the treatment of demyelination
US7459442B2 (en) 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
CN1756755A (zh) 2003-03-07 2006-04-05 先灵公司 取代的2－吖丁啶酮化合物、其制剂及其治疗高胆甾醇血症的用途
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WO2004081002A1 (en) * 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
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JP2005015434A (ja) * 2003-06-27 2005-01-20 Kotobuki Seiyaku Kk 血清コレステロール低下剤或はアテローム性硬化症の予防又は治療剤
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PT2807099T (pt) 2012-01-26 2017-02-08 Intralot Sa Integrated Lottery Systems & Services Métodos e sistemas para dispensa e tiragem

Also Published As

Publication number Publication date
SG45147A1 (en) 1998-01-16
HRP931515B1 (en) 2000-02-29
CN1090479C (zh) 2002-09-11
EE03383B1 (et) 2001-04-16
CZ164395A3 (en) 1996-03-13
CN1095591A (zh) 1994-11-30
CA2152351A1 (en) 1994-07-07
NO311325B1 (no) 2001-11-19
PL174128B1 (pl) 1998-06-30
SK281173B6 (sk) 2000-12-11
PL309636A1 (en) 1995-10-30
ZA939552B (en) 1994-10-12
DK0675714T3 (da) 1999-09-13
DE69323213T2 (de) 1999-07-08
WO1994014433A1 (en) 1994-07-07
JP3992728B2 (ja) 2007-10-17
DE69323213D1 (de) 1999-03-04
FI952916L (fi) 1995-06-14
LT3300B (en) 1995-06-26
SI9300677A (en) 1994-09-30
SK78395A3 (en) 1996-05-08
YU49060B (sh) 2003-08-29
EP0675714B1 (en) 1999-01-20
JPH08505141A (ja) 1996-06-04
HUT72081A (en) 1996-03-28
FI952916A0 (fi) 1995-06-14
ATE175872T1 (de) 1999-02-15
CZ287125B6 (en) 2000-09-13
MX9308053A (es) 1994-06-30
AU5872094A (en) 1994-07-19
HU9501854D0 (en) 1995-08-28
EP0675714A1 (en) 1995-10-11
AU680864B2 (en) 1997-08-14
LV10919B (en) 1996-04-20
LTIP1514A (en) 1994-10-25
US5661145A (en) 1997-08-26
GR3029405T3 (en) 1999-05-28
LV10919A (lv) 1995-12-20
YU80293A (sh) 1997-12-05
KR100306936B1 (ko) 2001-11-30
MY109538A (en) 1997-02-28
CA2152351C (en) 2009-09-22
IL108112A (en) 1999-11-30
NO952529D0 (no) 1995-06-23
NO952529L (no) 1995-06-23
EE9400341A (et) 1996-04-15
FI952916A7 (fi) 1995-06-14
ES2128552T3 (es) 1999-05-16
NZ259790A (en) 1997-02-24
HU221724B1 (hu) 2002-12-28
IL108112A0 (en) 1994-04-12
HRP931515A2 (en) 1996-12-31

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