TW319698B - - Google Patents

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Publication number
TW319698B
TW319698B TW082110824A TW82110824A TW319698B TW 319698 B TW319698 B TW 319698B TW 082110824 A TW082110824 A TW 082110824A TW 82110824 A TW82110824 A TW 82110824A TW 319698 B TW319698 B TW 319698B
Authority
TW
Taiwan
Prior art keywords
lower alkyl
group
inhibitor
alkoxy
scope
Prior art date
Application number
TW082110824A
Other languages
English (en)
Chinese (zh)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of TW319698B publication Critical patent/TW319698B/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TW082110824A 1992-12-23 1993-12-21 TW319698B (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US99548892A 1992-12-23 1992-12-23

Publications (1)

Publication Number Publication Date
TW319698B true TW319698B (enExample) 1997-11-11

Family

ID=25541876

Family Applications (1)

Application Number Title Priority Date Filing Date
TW082110824A TW319698B (enExample) 1992-12-23 1993-12-21

Country Status (32)

Country Link
US (1) US5661145A (enExample)
EP (1) EP0675714B1 (enExample)
JP (1) JP3992728B2 (enExample)
KR (1) KR100306936B1 (enExample)
CN (1) CN1090479C (enExample)
AT (1) ATE175872T1 (enExample)
AU (1) AU680864B2 (enExample)
CA (1) CA2152351C (enExample)
CZ (1) CZ287125B6 (enExample)
DE (1) DE69323213T2 (enExample)
DK (1) DK0675714T3 (enExample)
EE (1) EE03383B1 (enExample)
ES (1) ES2128552T3 (enExample)
FI (1) FI952916L (enExample)
GR (1) GR3029405T3 (enExample)
HR (1) HRP931515B1 (enExample)
HU (1) HU221724B1 (enExample)
IL (1) IL108112A (enExample)
LT (1) LT3300B (enExample)
LV (1) LV10919B (enExample)
MX (1) MX9308053A (enExample)
MY (1) MY109538A (enExample)
NO (1) NO311325B1 (enExample)
NZ (1) NZ259790A (enExample)
PL (1) PL174128B1 (enExample)
SG (1) SG45147A1 (enExample)
SI (1) SI9300677A (enExample)
SK (1) SK281173B6 (enExample)
TW (1) TW319698B (enExample)
WO (1) WO1994014433A1 (enExample)
YU (1) YU49060B (enExample)
ZA (1) ZA939552B (enExample)

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SI20109A (sl) * 1998-12-16 2000-06-30 LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. Stabilna farmacevtska formulacija
WO2000063703A1 (en) 1999-04-16 2000-10-26 Schering Corporation Use of azetidinone compounds
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US6979462B1 (en) * 2000-10-03 2005-12-27 Mutual Pharmaceutical Co., Inc. Stabilization of solid drug formulations
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US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
RS20100015A (sr) 2001-01-26 2010-12-31 Schering Corporation Kombinacija aktivatora receptora aktiviranog peroksizom- proliferatorom (ppar) fenofibrata sa inhibitorom apsorpcije sterola ezetimibom za vaskularne indikacije
HU230435B1 (hu) 2001-01-26 2016-06-28 Merck Sharp & Dohme Corp Szubsztituált azetidinon vegyületek alkalmazása szitoszterinémia kezelésére
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US6627757B2 (en) 2001-03-28 2003-09-30 Schering Corporation Enantioselective synthesis of azetidinone intermediate compounds
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US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US7056906B2 (en) 2001-09-21 2006-06-06 Schering Corporation Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
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AR040588A1 (es) 2002-07-26 2005-04-13 Schering Corp Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
JP4654035B2 (ja) 2002-11-05 2011-03-16 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 抗菌剤
MXPA05004811A (es) 2002-11-06 2005-07-22 Schering Corp Inhibidores de absorcion de colesterol para el tratamiento de trastornos autoinmunes.
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MXPA05009501A (es) * 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
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JP2024522718A (ja) 2021-06-16 2024-06-21 セルジーン コーポレーション 神経変性疾患の治療のための、カルボン酸基を含むアゼチジニル化合物

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Also Published As

Publication number Publication date
FI952916A0 (fi) 1995-06-14
US5661145A (en) 1997-08-26
FI952916A7 (fi) 1995-06-14
EE9400341A (et) 1996-04-15
EP0675714A1 (en) 1995-10-11
MY109538A (en) 1997-02-28
DE69323213D1 (de) 1999-03-04
KR100306936B1 (ko) 2001-11-30
LV10919A (lv) 1995-12-20
YU49060B (sh) 2003-08-29
LTIP1514A (en) 1994-10-25
EE03383B1 (et) 2001-04-16
SK78395A3 (en) 1996-05-08
LV10919B (en) 1996-04-20
SK281173B6 (sk) 2000-12-11
ZA939552B (en) 1994-10-12
FI952916L (fi) 1995-06-14
CA2152351C (en) 2009-09-22
IL108112A0 (en) 1994-04-12
HUT72081A (en) 1996-03-28
HU9501854D0 (en) 1995-08-28
CZ287125B6 (en) 2000-09-13
YU80293A (sh) 1997-12-05
EP0675714B1 (en) 1999-01-20
CZ164395A3 (en) 1996-03-13
AU5872094A (en) 1994-07-19
JP3992728B2 (ja) 2007-10-17
WO1994014433A1 (en) 1994-07-07
NO311325B1 (no) 2001-11-19
PL174128B1 (pl) 1998-06-30
AU680864B2 (en) 1997-08-14
NZ259790A (en) 1997-02-24
CN1095591A (zh) 1994-11-30
NO952529L (no) 1995-06-23
MX9308053A (es) 1994-06-30
DK0675714T3 (da) 1999-09-13
HRP931515B1 (en) 2000-02-29
HRP931515A2 (en) 1996-12-31
ES2128552T3 (es) 1999-05-16
SG45147A1 (en) 1998-01-16
HU221724B1 (hu) 2002-12-28
JPH08505141A (ja) 1996-06-04
PL309636A1 (en) 1995-10-30
NO952529D0 (no) 1995-06-23
ATE175872T1 (de) 1999-02-15
DE69323213T2 (de) 1999-07-08
SI9300677A (en) 1994-09-30
IL108112A (en) 1999-11-30
LT3300B (en) 1995-06-26
CA2152351A1 (en) 1994-07-07
CN1090479C (zh) 2002-09-11
GR3029405T3 (en) 1999-05-28

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