DE69323213D1 - Kombination eines Hemmers der Cholesterin-Biosynthese und eines beta-laktamischem Hemmers der Cholesterinabsorption - Google Patents

Kombination eines Hemmers der Cholesterin-Biosynthese und eines beta-laktamischem Hemmers der Cholesterinabsorption

Info

Publication number
DE69323213D1
DE69323213D1 DE69323213T DE69323213T DE69323213D1 DE 69323213 D1 DE69323213 D1 DE 69323213D1 DE 69323213 T DE69323213 T DE 69323213T DE 69323213 T DE69323213 T DE 69323213T DE 69323213 D1 DE69323213 D1 DE 69323213D1
Authority
DE
Germany
Prior art keywords
inhibitor
cholesterol
pct
beta
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69323213T
Other languages
English (en)
Other versions
DE69323213T2 (de
Inventor
Harry Davis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of DE69323213D1 publication Critical patent/DE69323213D1/de
Application granted granted Critical
Publication of DE69323213T2 publication Critical patent/DE69323213T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
DE69323213T 1992-12-23 1993-12-21 Kombination eines Hemmers der Cholesterin-Biosynthese und eines beta-laktamischem Hemmers der Cholesterinabsorption Expired - Lifetime DE69323213T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99548892A 1992-12-23 1992-12-23
PCT/US1993/012291 WO1994014433A1 (en) 1992-12-23 1993-12-21 COMBINATION OF A CHOLESTEROL BIOSYNTHESIS INHIBITOR AND A β-LACTAM CHOLESTEROL ABSORPTION INHIBITOR

Publications (2)

Publication Number Publication Date
DE69323213D1 true DE69323213D1 (de) 1999-03-04
DE69323213T2 DE69323213T2 (de) 1999-07-08

Family

ID=25541876

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69323213T Expired - Lifetime DE69323213T2 (de) 1992-12-23 1993-12-21 Kombination eines Hemmers der Cholesterin-Biosynthese und eines beta-laktamischem Hemmers der Cholesterinabsorption

Country Status (32)

Country Link
US (1) US5661145A (de)
EP (1) EP0675714B1 (de)
JP (1) JP3992728B2 (de)
KR (1) KR100306936B1 (de)
CN (1) CN1090479C (de)
AT (1) ATE175872T1 (de)
AU (1) AU680864B2 (de)
CA (1) CA2152351C (de)
CZ (1) CZ287125B6 (de)
DE (1) DE69323213T2 (de)
DK (1) DK0675714T3 (de)
EE (1) EE03383B1 (de)
ES (1) ES2128552T3 (de)
FI (1) FI952916A0 (de)
GR (1) GR3029405T3 (de)
HR (1) HRP931515B1 (de)
HU (1) HU221724B1 (de)
IL (1) IL108112A (de)
LT (1) LT3300B (de)
LV (1) LV10919B (de)
MX (1) MX9308053A (de)
MY (1) MY109538A (de)
NO (1) NO311325B1 (de)
NZ (1) NZ259790A (de)
PL (1) PL174128B1 (de)
SG (1) SG45147A1 (de)
SI (1) SI9300677A (de)
SK (1) SK281173B6 (de)
TW (1) TW319698B (de)
WO (1) WO1994014433A1 (de)
YU (1) YU49060B (de)
ZA (1) ZA939552B (de)

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US4680391A (en) * 1983-12-01 1987-07-14 Merck & Co., Inc. Substituted azetidinones as anti-inflammatory and antidegenerative agents
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US9205972B2 (en) 2012-01-26 2015-12-08 Intralot S.A.—Integrated Lottery Systems and Services Methods and systems for dispensing

Also Published As

Publication number Publication date
AU680864B2 (en) 1997-08-14
EP0675714B1 (de) 1999-01-20
NO952529L (no) 1995-06-23
FI952916A (fi) 1995-06-14
IL108112A0 (en) 1994-04-12
LV10919B (en) 1996-04-20
AU5872094A (en) 1994-07-19
HRP931515A2 (en) 1996-12-31
YU80293A (sh) 1997-12-05
FI952916A0 (fi) 1995-06-14
CZ164395A3 (en) 1996-03-13
ES2128552T3 (es) 1999-05-16
LTIP1514A (en) 1994-10-25
IL108112A (en) 1999-11-30
HRP931515B1 (en) 2000-02-29
LV10919A (lv) 1995-12-20
US5661145A (en) 1997-08-26
GR3029405T3 (en) 1999-05-28
TW319698B (de) 1997-11-11
EE03383B1 (et) 2001-04-16
JPH08505141A (ja) 1996-06-04
NO952529D0 (no) 1995-06-23
CA2152351A1 (en) 1994-07-07
YU49060B (sh) 2003-08-29
MY109538A (en) 1997-02-28
HU221724B1 (hu) 2002-12-28
KR100306936B1 (ko) 2001-11-30
LT3300B (en) 1995-06-26
CN1090479C (zh) 2002-09-11
CN1095591A (zh) 1994-11-30
SK78395A3 (en) 1996-05-08
HUT72081A (en) 1996-03-28
MX9308053A (es) 1994-06-30
SG45147A1 (en) 1998-01-16
HU9501854D0 (en) 1995-08-28
ZA939552B (en) 1994-10-12
SI9300677A (en) 1994-09-30
ATE175872T1 (de) 1999-02-15
SK281173B6 (sk) 2000-12-11
EP0675714A1 (de) 1995-10-11
CA2152351C (en) 2009-09-22
EE9400341A (et) 1996-04-15
CZ287125B6 (en) 2000-09-13
NZ259790A (en) 1997-02-24
PL309636A1 (en) 1995-10-30
DK0675714T3 (da) 1999-09-13
WO1994014433A1 (en) 1994-07-07
DE69323213T2 (de) 1999-07-08
JP3992728B2 (ja) 2007-10-17
NO311325B1 (no) 2001-11-19
PL174128B1 (pl) 1998-06-30

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