TW287110B - - Google Patents

Info

Publication number
TW287110B
TW287110B TW084111233A TW84111233A TW287110B TW 287110 B TW287110 B TW 287110B TW 084111233 A TW084111233 A TW 084111233A TW 84111233 A TW84111233 A TW 84111233A TW 287110 B TW287110 B TW 287110B
Authority
TW
Taiwan
Application number
TW084111233A
Other languages
Chinese (zh)
Inventor
M Platz Robert
Original Assignee
Inhale Therapeutic Syst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inhale Therapeutic Syst filed Critical Inhale Therapeutic Syst
Application granted granted Critical
Publication of TW287110B publication Critical patent/TW287110B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0035Piercing means
    • A61M15/0036Piercing means hollow piercing means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/004Details of the piercing or cutting means with fixed piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033Details of the piercing or cutting means
    • A61M15/0041Details of the piercing or cutting means with movable piercing or cutting means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0028Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0053Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal
    • A61M15/0055Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type or way of disposal the used dosages being coiled
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0233Conductive materials, e.g. antistatic coatings for spark prevention
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/07General characteristics of the apparatus having air pumping means
    • A61M2205/071General characteristics of the apparatus having air pumping means hand operated
    • A61M2205/073Syringe, piston type
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/60General characteristics of the apparatus with identification means
    • A61M2205/6045General characteristics of the apparatus with identification means having complementary physical shapes for indexing or registration purposes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Catching Or Destruction (AREA)
  • Nozzles (AREA)
TW084111233A 1994-09-21 1995-10-24 TW287110B (oth)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/309,691 US5785049A (en) 1994-09-21 1994-09-21 Method and apparatus for dispersion of dry powder medicaments
US08/487,184 US5740794A (en) 1994-09-21 1995-06-07 Apparatus and methods for dispersing dry powder medicaments

Publications (1)

Publication Number Publication Date
TW287110B true TW287110B (oth) 1996-10-01

Family

ID=23199254

Family Applications (1)

Application Number Title Priority Date Filing Date
TW084111233A TW287110B (oth) 1994-09-21 1995-10-24

Country Status (8)

Country Link
US (2) US5785049A (oth)
EP (1) EP1917992A3 (oth)
KR (3) KR100399844B1 (oth)
AR (1) AR042921A2 (oth)
DE (1) DE69535725T2 (oth)
MY (1) MY113727A (oth)
TW (1) TW287110B (oth)
ZA (1) ZA957933B (oth)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115666284A (zh) * 2020-05-27 2023-01-31 约瑟夫公司 用于吸入物质的装置

Families Citing this family (342)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9004781D0 (en) * 1990-03-02 1990-04-25 Glaxo Group Ltd Device
HU213221B (en) 1990-03-02 1997-03-28 Glaxo Group Ltd Inhalation device and medicine packet for device
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
UA26230A (uk) * 1990-03-02 1999-07-19 Глексо Груп Лімітед Іhгалятор для спільhого використаhhя з лікувальhим блоком і лікувальhий блок
ES2284226T3 (es) * 1991-07-02 2007-11-01 Nektar Therapeutics Dispositivo para proporcionar medicamentos en aerosol.
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
CA2200727C (en) * 1994-09-21 2006-11-28 Adrian E. Smith Apparatus and methods for dispersing dry powder medicaments
JP4484247B2 (ja) * 1995-02-24 2010-06-16 エラン ファーマ インターナショナル,リミティド ナノ粒子分散体を含有するエアロゾル
ATE287703T1 (de) * 1995-04-14 2005-02-15 Nektar Therapeutics Pulverförmige pharmazeutische formulierungen mit verbesserter dispergierbarkeit
US6428771B1 (en) * 1995-05-15 2002-08-06 Pharmaceutical Discovery Corporation Method for drug delivery to the pulmonary system
US20040237961A1 (en) * 1995-06-08 2004-12-02 Snow John Medlin Inhalation actuated device for use with metered dose inhalers (MDIs)
US6672304B1 (en) 1995-06-08 2004-01-06 Innovative Devices, Llc Inhalation actuated device for use with metered dose inhalers (MDIs)
US6209538B1 (en) 1995-08-02 2001-04-03 Robert A. Casper Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
FR2738152B1 (fr) * 1995-09-04 1998-01-23 Tebro Dispositif de pre-dosage de produit pulverulent pour un distributeur de produit
NZ331361A (en) * 1996-02-21 2000-01-28 Schering Corp Powder inhaler including swirl means for changing the flow direction of the powder and chimney means for reversing the flow direction
ES2183168T3 (es) * 1996-04-25 2003-03-16 Astrazeneca Ab Inhalador.
US6187214B1 (en) 1996-05-13 2001-02-13 Universidad De Seville Method and device for production of components for microfabrication
US6405936B1 (en) 1996-05-13 2002-06-18 Universidad De Sevilla Stabilized capillary microjet and devices and methods for producing same
US6189803B1 (en) 1996-05-13 2001-02-20 University Of Seville Fuel injection nozzle and method of use
US6792940B2 (en) * 1996-05-13 2004-09-21 Universidad De Sevilla Device and method for creating aerosols for drug delivery
US6386463B1 (en) 1996-05-13 2002-05-14 Universidad De Sevilla Fuel injection nozzle and method of use
US6595202B2 (en) 1996-05-13 2003-07-22 Universidad De Sevilla Device and method for creating aerosols for drug delivery
US6196525B1 (en) 1996-05-13 2001-03-06 Universidad De Sevilla Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber
ES2140998B1 (es) * 1996-05-13 2000-10-16 Univ Sevilla Procedimiento de atomizacion de liquidos.
US6116516A (en) 1996-05-13 2000-09-12 Universidad De Sevilla Stabilized capillary microjet and devices and methods for producing same
US6299145B1 (en) 1996-05-13 2001-10-09 Universidad De Sevilla Device and method for fluid aeration via gas forced through a liquid within an orifice of a pressure chamber
US6458574B1 (en) 1996-09-12 2002-10-01 Transkaryotic Therapies, Inc. Treatment of a α-galactosidase a deficiency
GB2318737B (en) * 1996-10-30 2000-06-14 Bespak Plc Improved inhalers
US20030203036A1 (en) 2000-03-17 2003-10-30 Gordon Marc S. Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
SE9700424D0 (sv) * 1997-02-07 1997-02-07 Astra Ab Powder inhaler
DE19704849B4 (de) * 1997-02-08 2011-02-17 Ing. Erich Pfeiffer Gmbh Austragvorrichtung für Medien
CA2212430A1 (en) 1997-08-07 1999-02-07 George Volgyesi Inhalation device
US20060165606A1 (en) * 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
PE56799A1 (es) * 1997-10-10 1999-06-10 Inhale Therapeutic Syst Metodo y aparato para transportar polvo
DE69814918T2 (de) 1997-12-17 2004-03-11 Universidad De Sevilla Vorrichtung und verfahren zur erzeugung von aerosolen für arzneimittelverabreichung
GEP20043260B (en) * 1998-03-16 2004-06-25 Nectar Therapeutics Aerosolized Active Agent Delivery and Device for Realization Thereof
SE9801114D0 (sv) * 1998-03-30 1998-03-30 Astra Ab Inhalation device
US6257233B1 (en) * 1998-06-04 2001-07-10 Inhale Therapeutic Systems Dry powder dispersing apparatus and methods for their use
SI1082155T1 (sl) * 1998-06-04 2007-02-28 Nektar Therapeutics Aparat za razsirjanje suhega prahu in postopek za uporabo
US6722363B1 (en) * 1998-06-22 2004-04-20 Astrazeneca Ab Device for emptying cavities containing powder by means of suction
US6593133B1 (en) 1998-07-06 2003-07-15 Nsgene A/S Neurotrophic factors
DE19831525A1 (de) * 1998-07-14 2000-01-20 Pfeiffer Erich Gmbh & Co Kg Spender für Medien
UA73722C2 (en) 1998-08-18 2005-09-15 Treatment of mucus hypersecretion in lungs by administration of epidermal growth factor receptor (egf-r) antagonist and pharmaceutical formulation
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
US20040141925A1 (en) * 1998-11-12 2004-07-22 Elan Pharma International Ltd. Novel triamcinolone compositions
US7521068B2 (en) * 1998-11-12 2009-04-21 Elan Pharma International Ltd. Dry powder aerosols of nanoparticulate drugs
US6450189B1 (en) 1998-11-13 2002-09-17 Universidad De Sevilla Method and device for production of components for microfabrication
HK1042825A1 (zh) 1998-12-22 2002-08-30 The University Of North Carolina At Chapel Hill 治疗气道疾病的化合物和方法以及气道药物的给药方法
TWI277425B (en) 1999-04-13 2007-04-01 Lilly Co Eli Pulmonary administration of dry powder formulations for treating infertility
PL352615A1 (en) 1999-06-05 2003-08-25 Innovata Biomed Ltd Delivery system
GB2353222B (en) * 1999-06-23 2001-09-19 Cambridge Consultants Inhalers
US9006175B2 (en) * 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
DK2280020T3 (en) * 1999-06-29 2016-05-02 Mannkind Corp Pharmaceutical formulations comprising a peptide complexed with a diketopiperazine
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7464706B2 (en) * 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
ATE271400T1 (de) * 1999-10-12 2004-08-15 Shl Medical Ab Inhalateur
AU775565B2 (en) * 1999-10-29 2004-08-05 Novartis Ag Dry powder compositions having improved dispersivity
US7304750B2 (en) 1999-12-17 2007-12-04 Nektar Therapeutics Systems and methods for non-destructive mass sensing
US20010029947A1 (en) 1999-12-17 2001-10-18 Steve Paboojian Receptacles to facilitate the extraction of powders
US20010035184A1 (en) 1999-12-17 2001-11-01 Carlos Schuler Systems and methods for treating packaged powders
AR027509A1 (es) 2000-01-10 2003-04-02 Maxygen Aps Conjugados g-csf
WO2001078817A1 (en) * 2000-02-25 2001-10-25 Dura Pharmaceuticals, Inc. Dosing system for a dry powder inhaler
US7089934B2 (en) 2000-02-28 2006-08-15 Vectura Limited Delivery of oral drugs
US6748944B1 (en) 2000-05-03 2004-06-15 Dellavecchia Michael Anthony Ultrasonic dosage device and method
US20030003057A1 (en) * 2000-07-07 2003-01-02 Jeffry Weers Methods for administering leuprolide by inhalation
US6948494B1 (en) * 2000-05-10 2005-09-27 Innovative Devices, Llc. Medicament container with same side airflow inlet and outlet and method of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
DK1280520T4 (en) 2000-05-10 2018-06-25 Novartis Ag Phospholipid based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US7326691B2 (en) * 2004-06-21 2008-02-05 Nektar Therapeutics Compositions comprising amphotericin B, methods, and systems
WO2001087378A2 (en) * 2000-05-12 2001-11-22 Dura Pharmaceuticals, Inc. Compressed gas dry powder inhaler
US6668827B2 (en) 2000-05-16 2003-12-30 Nektar Therapeutics Systems devices and methods for opening receptacles having a powder to be fluidized
US20020000225A1 (en) 2000-06-02 2002-01-03 Carlos Schuler Lockout mechanism for aerosol drug delivery devices
GB2364919A (en) * 2000-07-21 2002-02-13 Cambridge Consultants Inhalers
WO2002013897A2 (en) * 2000-08-14 2002-02-21 Advanced Inhalation Research, Inc. Inhalation device and method
SE517227C2 (sv) * 2000-09-25 2002-05-14 Microdrug Ag Inhalator för torrt pulver med folieskärare
GB0023654D0 (en) * 2000-09-27 2000-11-08 Cambridge Consultants Device for administering doses of particulate material
US6443152B1 (en) * 2001-01-12 2002-09-03 Becton Dickinson And Company Medicament respiratory delivery device
US6722364B2 (en) * 2001-01-12 2004-04-20 Becton, Dickinson And Company Medicament inhalation delivery devices and methods for using the same
WO2002056948A1 (en) * 2001-01-17 2002-07-25 Vectura Limited An inhaler device
US7442370B2 (en) 2001-02-01 2008-10-28 Biogen Idec Ma Inc. Polymer conjugates of mutated neublastin
DE60221640T2 (de) * 2001-02-06 2008-05-21 Innovata Biomed Ltd., St. Albans Bimodale trockenpulverzusammensetzung zur inhalation
IL156059A0 (en) 2001-02-27 2003-12-23 Maxygen Aps NEW INTERFERON beta-LIKE MOLECULES
US7276580B2 (en) * 2001-03-12 2007-10-02 Biogen Idec Ma Inc. Neurotrophic factors
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
US6766799B2 (en) * 2001-04-16 2004-07-27 Advanced Inhalation Research, Inc. Inhalation device
US7025058B2 (en) * 2001-04-26 2006-04-11 New England Pharmaceuticals, Inc. Metered dose delivery device for liquid and powder agents
US7905230B2 (en) * 2001-05-09 2011-03-15 Novartis Ag Metered dose inhaler with lockout
KR20040023597A (ko) * 2001-05-10 2004-03-18 벡투라 딜리버리 디바이시스 리미티드 흡입기들
GB0112888D0 (en) * 2001-05-26 2001-07-18 Innovata Biomed Ltd Device
EG24184A (en) * 2001-06-15 2008-10-08 Otsuka Pharma Co Ltd Dry powder inhalation system for transpulmonary
ES2431634T3 (es) 2001-06-20 2013-11-27 Novartis Ag Dispositivo de administración de aerosol
TW553752B (en) * 2001-06-20 2003-09-21 Inhale Therapeutic Syst Powder aerosolization apparatus and method
EP1270012A1 (en) * 2001-06-21 2003-01-02 Pfizer Products Inc. Use of pulmonary administration of insulin for treatment of diabetes
US7231919B2 (en) * 2001-09-28 2007-06-19 Kurve Technology, Inc. Particle dispersion device for nasal delivery
US6779520B2 (en) * 2001-10-30 2004-08-24 Iep Pharmaceutical Devices Inc. Breath actuated dry powder inhaler
GB0128148D0 (en) * 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
US20030099601A1 (en) * 2001-11-27 2003-05-29 Gordon Marc S. Inhalation lung surfactant therapy
SI1458360T1 (sl) 2001-12-19 2011-08-31 Novartis Ag Pulmonalno dajanje aminoglikozidov
JP2005514273A (ja) * 2001-12-21 2005-05-19 ネクター セラピューティクス 包装における医薬製剤の密封
WO2003057593A1 (en) * 2001-12-21 2003-07-17 Nektar Therapeutics Capsule package with moisture barrier
US20030129242A1 (en) * 2002-01-04 2003-07-10 Bosch H. William Sterile filtered nanoparticulate formulations of budesonide and beclomethasone having tyloxapol as a surface stabilizer
PT1494732E (pt) 2002-03-20 2008-03-20 Mannkind Corp Aparelho de inalação
GR1004350B (el) * 2002-03-29 2003-09-26 Συσκευη εισπνοων ξηρης σκονης
US20030235538A1 (en) * 2002-04-09 2003-12-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Method for the administration of an anticholinergic by inhalation
EP1503788B1 (en) 2002-04-25 2011-06-29 Shire Human Genetic Therapies, Inc. Treatment of alpha-galactosidase a deficiency
AU2003249623A1 (en) * 2002-05-09 2003-12-12 Kurve Technology, Inc. Particle dispersion chamber for nasal nebulizer
US6889690B2 (en) 2002-05-10 2005-05-10 Oriel Therapeutics, Inc. Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages
US7185651B2 (en) * 2002-06-18 2007-03-06 Nektar Therapeutics Flow regulator for aerosol drug delivery and methods
US6799571B1 (en) * 2002-06-19 2004-10-05 Molecular Rotation, Llc Medicinal powder delivery system
US6941980B2 (en) * 2002-06-27 2005-09-13 Nektar Therapeutics Apparatus and method for filling a receptacle with powder
JP4571776B2 (ja) * 2002-11-05 2010-10-27 Jx日鉱日石エネルギー株式会社 潤滑油組成物
WO2005000195A2 (en) * 2002-11-13 2005-01-06 Rosenberg Yvonne J A pretreatment or post exposure treatment for exposure to a toxic substance by pulmonary delivery (inhaler) of a bioscavenger
US7516741B2 (en) * 2002-12-06 2009-04-14 Novartis Ag Aerosolization apparatus with feedback mechanism
UA84412C2 (ru) * 2002-12-13 2008-10-27 Оцука Фармасьютікал Ко., Лтд. Ингаляционное устройство для транспульмонального введения (варианты)
AU2003303036A1 (en) * 2002-12-13 2004-07-09 Pfizer Products Inc. Method of decreasing hepatic glucose output in diabetic patients
WO2004056287A1 (en) * 2002-12-19 2004-07-08 Koninklijke Philips Electronics N.V. Discrete-amount fluid-dispensing system for a personal care device
US20040206350A1 (en) * 2002-12-19 2004-10-21 Nektar Therapeutics Aerosolization apparatus with non-circular aerosolization chamber
US20050236296A1 (en) * 2002-12-30 2005-10-27 Nektar Therapeutics (Formerly Inhale Therapeutic Systems, Inc.) Carry case for aerosolization apparatus
CA2508870C (en) 2002-12-30 2012-10-16 Nektar Therapeutics Prefilming atomizer
KR20050088242A (ko) * 2002-12-31 2005-09-02 넥타르 테라퓨틱스 진균 감염 요법을 위한 에어로졸화가능한 약제학적 제형물
US7669596B2 (en) * 2002-12-31 2010-03-02 Novartis Pharma Ag Aerosolization apparatus with rotating capsule
PL378270A1 (pl) * 2002-12-31 2006-03-20 Nektar Therapeutics Preparat farmaceutyczny zawierający nierozpuszczalny środek czynny
US20040187866A1 (en) * 2003-03-31 2004-09-30 Nathaniel Hughes Liquid medicament delivery system
KR101066788B1 (ko) * 2003-04-09 2011-09-21 노바르티스 아게 공기 입구 차폐 부재를 갖춘 에어로졸화 장치
WO2004091707A2 (en) 2003-04-09 2004-10-28 Nektar Therapeutics Aerosolization apparatus with capsule puncture alignment guide
US8869794B1 (en) 2003-04-09 2014-10-28 Novartis Pharma Ag Aerosolization apparatus with capsule puncturing member
DK1897552T3 (da) 2003-04-18 2009-10-05 Biogen Idec Inc Polymer-konjugeret glycosyleret neublastin
US7064129B2 (en) 2003-08-18 2006-06-20 Parion Sciences, Inc. Capped pyrazinoylguanidine sodium channel blockers
US8001963B2 (en) * 2003-09-05 2011-08-23 Kurve Technology, Inc. Integrated nebulizer and particle dispersion chamber for nasal delivery of medicament to deep nasal cavity and paranasal sinuses
US20070131230A1 (en) * 2003-09-05 2007-06-14 Kurve Technology, Inc. Nasal adapter for the base of the nose
GB2405798A (en) 2003-09-15 2005-03-16 Vectura Ltd Dry powder inhaler with primary and secondary piercing elements and a medicament pack for use with an inhalation device.
GB0322544D0 (en) * 2003-09-26 2003-10-29 Innovata Biomed Ltd Apparatus
US7338171B2 (en) * 2003-10-27 2008-03-04 Jen-Chuen Hsieh Method and apparatus for visual drive control
US7451761B2 (en) * 2003-10-27 2008-11-18 Oriel Therapeutics, Inc. Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances
US7377277B2 (en) * 2003-10-27 2008-05-27 Oriel Therapeutics, Inc. Blister packages with frames and associated methods of fabricating dry powder drug containment systems
US20050214224A1 (en) * 2003-11-04 2005-09-29 Nektar Therapeutics Lipid formulations for spontaneous drug encapsulation
SE0303270L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Metod för administration av tiotropium
SE0303569L (sv) * 2003-12-03 2005-06-04 Microdrug Ag DPI för avlämning av fuktkänsliga medikament
CA2547782A1 (en) * 2003-12-03 2005-06-16 Microdrug Ag Medical product containing tiotropium
SE0303570L (sv) * 2003-12-03 2005-06-04 Microdrug Ag Fukt-känslig medicinsk produkt
US7159507B2 (en) 2003-12-23 2007-01-09 Philip Morris Usa Inc. Piston pump useful for aerosol generation
EP1701714A2 (en) * 2004-01-07 2006-09-20 Nektar Therapeutics Improved sustained release compositions for pulmonary administration of insulin
JP2007517892A (ja) * 2004-01-12 2007-07-05 マンカインド コーポレイション 2型糖尿病における血清プロインスリンレベルを低下させる方法
US7624733B2 (en) 2004-02-09 2009-12-01 Oriel Therapeutics, Inc. Inhalers with extendable/retractable forward member and associated methods of dispensing inhalant substances
EP1713441A2 (en) * 2004-02-12 2006-10-25 Nektar Therapeutics Interleukin-13 antagonist powders, spray-dried particles, and methods
CN1922836A (zh) * 2004-02-26 2007-02-28 诺和诺德公司 一种用于对无线通信设备进行安全配对的方法和系统
ES2328048T3 (es) * 2004-03-12 2009-11-06 Biodel, Inc. Composiciones de insulina con absorcion mejorada.
US20080090753A1 (en) * 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
JP2007529928A (ja) * 2004-03-19 2007-10-25 ノボ・ノルデイスク・エー/エス 医療用デバイスのデータ伝送に使用されるパケットヘッダのフォーマットサイズの削減
EP1735729A2 (en) * 2004-03-26 2006-12-27 Novo Nordisk A/S Device for displaying data relevant for a diabetic patient
GB0407627D0 (en) * 2004-04-02 2004-05-05 Vectura Ltd Corkscrew pump
JP2007533387A (ja) * 2004-04-21 2007-11-22 イノベータ バイオメド リミテッド 吸入器
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
US7727962B2 (en) * 2004-05-10 2010-06-01 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder comprising new compositions of oligosaccharides and methods for their preparation
US7611709B2 (en) * 2004-05-10 2009-11-03 Boehringer Ingelheim Pharma Gmbh And Co. Kg 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives
US7723306B2 (en) * 2004-05-10 2010-05-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Spray-dried powder comprising at least one 1,4 O-linked saccharose-derivative and methods for their preparation
SE530006C2 (sv) * 2004-06-18 2008-02-05 Mederio Ag Inhalator som använder balja
BE1015883A3 (fr) * 2004-06-08 2005-10-04 Occhio Procede et dispositif de dispersion de poudres seches.
KR20120131245A (ko) 2004-06-18 2012-12-04 노파르티스 아게 기관지 감염의 치료 방법
US8513204B2 (en) * 2004-06-21 2013-08-20 Novartis Ag Compositions comprising amphotericin B, mehods and systems
CN101027318B (zh) 2004-07-19 2016-05-25 比奥孔有限公司 胰岛素-低聚物共轭物,制剂及其用途
EP2238983B1 (en) * 2004-08-19 2014-07-23 Biogen Idec MA Inc. Neublastin variants
AU2005277227B2 (en) * 2004-08-19 2011-10-06 Biogen Ma Inc. Refolding transforming growth factor beta family proteins
MX2007001903A (es) 2004-08-20 2007-08-02 Mannkind Corp Catalisis de sintesis de dicetopiperazina.
KR20130066695A (ko) 2004-08-23 2013-06-20 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
US20080270186A1 (en) * 2004-08-24 2008-10-30 Soren Mikkelsen Giving a Service to a Patient
EA200700743A1 (ru) * 2004-10-06 2007-10-26 Бёрингер Ингельхайм Интернациональ Гмбх Устройство для распыления порошка, устройство для хранения порошка и способ распыления порошка
GB0426780D0 (en) * 2004-12-07 2005-01-12 3M Innovative Properties Co Pressurized inhalation devices
GB0427853D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
GB0427858D0 (en) * 2004-12-20 2005-01-19 Glaxo Group Ltd Manifold for use in medicament dispenser
GB0428169D0 (en) * 2004-12-23 2005-01-26 3M Innovative Properties Co Pressurized inhalation devices
FR2881111B1 (fr) * 2005-01-25 2010-07-30 Valois Sas Dispositif de distribution de produit fluide.
US8206360B2 (en) 2005-02-01 2012-06-26 Intelliject, Inc. Devices, systems and methods for medicament delivery
US9022980B2 (en) 2005-02-01 2015-05-05 Kaleo, Inc. Medical injector simulation device
US8361026B2 (en) 2005-02-01 2013-01-29 Intelliject, Inc. Apparatus and methods for self-administration of vaccines and other medicaments
US8231573B2 (en) 2005-02-01 2012-07-31 Intelliject, Inc. Medicament delivery device having an electronic circuit system
DK2058020T3 (da) * 2005-02-01 2013-01-07 Intelliject Inc Indretning til indgivelse af lægemiddel
WO2006088894A2 (en) * 2005-02-15 2006-08-24 Elan Pharma International Limited Aerosol and injectable formulations of nanoparticulate benzodiazepine
CN101175480A (zh) * 2005-03-16 2008-05-07 伊兰制药国际有限公司 纳米微粒白三烯受体拮抗剂/皮质类固醇制剂
US8003127B2 (en) * 2005-03-23 2011-08-23 Elan Pharma International Limited Nanoparticulate corticosteroid and antihistamine formulations methods of making, and methods of administering thereof
GB0507711D0 (en) 2005-04-15 2005-05-25 Vectura Group Plc Improved blister piercing
UA95446C2 (ru) 2005-05-04 2011-08-10 Іллюміджен Байосайєнсіз, Інк. Мутаци в генах oas1
EP1901749B1 (en) 2005-05-18 2016-08-03 Raptor Pharmaceuticals Inc. Aerosolized fluoroquinolones and uses thereof
KR101348594B1 (ko) 2005-05-18 2014-01-07 노바르티스 아게 기관지 치료를 위한 밸브, 장치 및 방법
US8546423B2 (en) 2005-05-18 2013-10-01 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
TWI274641B (en) * 2005-08-30 2007-03-01 Rexon Ind Corp Ltd Cutting machine
CA2621083C (en) 2005-08-30 2017-04-11 University Of Miami Immunomodulating tumor necrosis factor receptor 25 (tnfr25) agonists, antagonists and immunotoxins
KR101486397B1 (ko) 2005-09-14 2015-01-28 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
US8084420B2 (en) * 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
WO2007041090A2 (en) * 2005-09-29 2007-04-12 Nektar Therapeutics Receptacles and kits, such as for dry powder packaging
WO2007041481A1 (en) * 2005-09-29 2007-04-12 Biodel, Inc. Rapid acting and prolonged acting insulin preparations
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
AR058290A1 (es) * 2005-12-12 2008-01-30 Glaxo Group Ltd Dispensador de medicamento
AR058289A1 (es) 2005-12-12 2008-01-30 Glaxo Group Ltd Colector para ser usado en dispensador de medicamento
WO2007075534A2 (en) 2005-12-16 2007-07-05 Nektar Therapeutics Al, Corporation Polymer conjugates of glp-1
BRPI0707991B8 (pt) 2006-02-22 2021-05-25 Mannkind Corp métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco
TWI501774B (zh) 2006-02-27 2015-10-01 Biogen Idec Inc 神經性病症之治療
US20100056440A1 (en) * 2006-03-01 2010-03-04 Biogen Idec Ma Inc. Compositions and methods for administering gdnf ligand family proteins
AU2011218649B8 (en) * 2006-03-29 2015-11-19 Kaleo, Inc. Devices, systems and methods for medicament delivery
DE102006016901A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Mundstück für einen Inhalator
DE102006016904A1 (de) * 2006-04-11 2007-10-25 Boehringer Ingelheim Pharma Gmbh & Co. Kg Inhalator
JP2009533471A (ja) * 2006-04-12 2009-09-17 バイオデル, インコーポレイテッド 即効型および長時間作用型組合せインスリン製剤
EP2106268B1 (en) 2006-08-30 2018-12-12 Kurve Technology, Inc. Aerosol generating and delivery device
EP2077882A2 (en) * 2006-10-25 2009-07-15 Nektar Therapeutics Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices
US8702836B2 (en) 2006-11-22 2014-04-22 Covaris, Inc. Methods and apparatus for treating samples with acoustic energy to form particles and particulates
WO2008091838A2 (en) 2007-01-22 2008-07-31 Intelliject, Inc. Medical injector with compliance tracking and monitoring
WO2008091355A2 (en) * 2007-01-24 2008-07-31 Breathe Pharmaceuticals, Inc. Drug transfer device
WO2008124522A2 (en) * 2007-04-04 2008-10-16 Biodel, Inc. Amylin formulations
ES2476253T3 (es) 2007-05-01 2014-07-14 Biogen Idec Ma Inc. P�ptidos de neublastina para su uso en el aumento de la vascularizaci�n en tejido con flujo sanguíneo deteriorado
ES2562806T3 (es) * 2007-06-05 2016-03-08 Paka Pulmonary Pharmaceuticals, Inc. Composiciones para administrar medicamentos en los pulmones, y usos de las mismas
WO2008156586A2 (en) * 2007-06-12 2008-12-24 Alkermes, Inc. Inhalation device for powdered substances
US20090110679A1 (en) * 2007-07-13 2009-04-30 Luk-Chiu Li Methods and compositions for pulmonary administration of a TNFa inhibitor
EP2020249A1 (de) * 2007-08-01 2009-02-04 Boehringer Ingelheim Pharma GmbH & Co. KG Inhalator
US20110135648A1 (en) * 2007-08-08 2011-06-09 Biogen Idec Ma Inc. Anti-neublastin antibodies and uses thereof
US8273561B2 (en) * 2007-10-05 2012-09-25 Nuron Biotech, Inc. High pressure treatment of aggregated interferons
US8785396B2 (en) 2007-10-24 2014-07-22 Mannkind Corporation Method and composition for treating migraines
RU2517140C2 (ru) * 2007-10-25 2014-05-27 Новартис Аг Способ обработки упаковки с однократной дозой лекартвенного препарата
JP5352596B2 (ja) * 2008-01-04 2013-11-27 バイオデル, インコーポレイテッド 組織グルコースレベルの関数としてのインスリン放出のためのインスリン製剤
MX344703B (es) 2008-02-26 2017-01-03 Parion Sciences Inc Bloqueadores de canal de sodio poliaromaticos.
KR101541209B1 (ko) * 2008-03-27 2015-07-31 맨카인드 코포레이션 건조 분말 흡입 시스템
US8021344B2 (en) 2008-07-28 2011-09-20 Intelliject, Inc. Medicament delivery device configured to produce an audible output
USD994111S1 (en) 2008-05-12 2023-08-01 Kaleo, Inc. Medicament delivery device cover
CA2724009C (en) * 2008-05-15 2016-10-11 Novartis Ag Pulmonary delivery of a fluoroquinolone
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
US9358352B2 (en) 2008-06-13 2016-06-07 Mannkind Corporation Dry powder drug delivery system and methods
RU2608439C2 (ru) 2008-06-13 2017-01-18 Маннкайнд Корпорейшн Ингалятор для сухого порошка и система для доставки лекарственных средств
EP2609954B1 (en) 2008-06-20 2021-12-29 MannKind Corporation An interactive apparatus for real-time profiling of inhalation efforts
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US20110171312A1 (en) * 2008-09-19 2011-07-14 Nektar Therapeutics Modified therapeutic peptides, methods of their preparation and use
WO2010033240A2 (en) * 2008-09-19 2010-03-25 Nektar Therapeutics Carbohydrate-based drug delivery polymers and conjugates thereof
CN102202649A (zh) 2008-10-07 2011-09-28 Mpex医药有限公司 用于改进的药物动力学的氟喹诺酮气雾剂制剂
PL2346509T3 (pl) 2008-10-07 2021-03-08 Horizon Orphan Llc Lewofloksacyna w postaci aerozolu dla zmniejszania stanu zapalnego płuc
GB0818476D0 (en) * 2008-10-09 2008-11-12 Vectura Delivery Device Ltd Inhaler
WO2010052479A1 (en) * 2008-11-06 2010-05-14 Medispray Laboratories Pvt. Ltd Inhaler device
WO2010068754A2 (en) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
GB0901520D0 (en) * 2009-01-30 2009-03-11 Vectura Delivery Devices Ltd Inhaler
US9060927B2 (en) * 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
EP2676695A3 (en) 2009-03-11 2017-03-01 MannKind Corporation Apparatus, system and method for measuring resistance of an inhaler
WO2010107964A1 (en) 2009-03-18 2010-09-23 Pleiades Cardio-Therapeutics, Inc. Unit doses, aerosols, kits, and methods for treating heart conditions by pulmonary administration
CN108434126B (zh) 2009-03-26 2021-11-19 普马特里克斯营业公司 治疗肺病的干粉配方与方法
AU2010232591A1 (en) 2009-04-01 2011-11-03 Promedior, Inc. Pulmonary and nasal delivery of serum amyloid P
CA2764759A1 (en) 2009-06-09 2010-12-16 Defyrus, Inc. Administration of interferon for prophylaxis against or treatment of pathogenic infection
CN102647979B (zh) 2009-06-12 2015-03-04 曼金德公司 具有确定比表面积的二酮哌嗪颗粒
ES2593428T3 (es) * 2009-06-25 2016-12-09 Boehringer Ingelheim Vetmedica Gmbh Inhalador
JP5656996B2 (ja) 2009-07-13 2015-01-21 ザ ユニバーシティ オブ ノース キャロライナ アット チャペル ヒル 工学的に作製されたエアロゾル粒子、およびそれに関連した方法
KR20120100904A (ko) 2009-09-04 2012-09-12 엠펙스 파마슈티컬즈, 인코포레이티드 낭포성 섬유증을 치료하기 위한 에어로졸화된 레보플록사신의 용도
WO2011035140A1 (en) 2009-09-18 2011-03-24 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of contrast moieties to the lungs
JP5718338B2 (ja) 2009-09-21 2015-05-13 ノボ・ノルデイスク・エー/エス キャップ機能を有する薬剤送達システムおよび装置
EP2496295A1 (en) 2009-11-03 2012-09-12 MannKind Corporation An apparatus and method for simulating inhalation efforts
US9227030B2 (en) * 2009-12-23 2016-01-05 Map Pharmaceuticals, Inc. Enhanced eductor design
HRP20160431T1 (hr) 2010-06-24 2016-05-20 Gilead Sciences, Inc. Pirazolo[1,5-a]pirimidini i triazini kao antivirusni agensi
EA025252B1 (ru) 2010-07-22 2016-12-30 Гайлид Сайэнсиз, Инк. Способы и соединения для лечения вирусных инфекций paramyxoviridae
WO2012030645A1 (en) 2010-08-30 2012-03-08 Pulmatrix, Inc. Respirably dry powder comprising calcium lactate, sodium chloride and leucine
AU2011296343B2 (en) 2010-08-30 2015-12-10 Pulmatrix Operating Company, Inc. Dry powder formulations and methods for treating pulmonary diseases
TW201305185A (zh) 2010-09-13 2013-02-01 Gilead Sciences Inc 用於抗病毒治療之2’-氟取代之碳-核苷類似物
ES2710537T3 (es) 2010-09-29 2019-04-25 Pulmatrix Operating Co Inc Polvos secos catiónicos
IL286573B (en) 2010-09-29 2022-08-01 Pulmatrix Operating Co Inc Monovalent metal cation dry powders for inhalation
US8459121B2 (en) * 2010-10-28 2013-06-11 Covaris, Inc. Method and system for acoustically treating material
WO2012094381A2 (en) 2011-01-05 2012-07-12 Hospira, Inc. Spray drying vancomycin
CA2824432C (en) 2011-01-31 2021-10-19 Genoa Pharmaceuticals, Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
BR122021002471B8 (pt) 2011-03-03 2022-10-25 Impel Neuropharma Inc Dispositivo de distribuição de droga nasal
EP2694402B1 (en) 2011-04-01 2017-03-22 MannKind Corporation Blister package for pharmaceutical cartridges
CA2754237A1 (en) 2011-05-27 2012-11-27 The Regents Of The University Of California Cyanoquinoline compounds having activity in correcting mutant-cftr processing and increasing ion transport and uses thereof
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
BR112013032771B1 (pt) 2011-06-27 2021-01-12 Parion Sciences, Inc. dipeptídio quimicamente e metabolicamente estável possuindo potente atividade bloqueadora de canais de sódio
US9004063B1 (en) * 2011-08-17 2015-04-14 Shane M. Guldbransen Portable oxygen inhaler device
LT5943B (lt) 2011-10-20 2013-06-25 Vilniaus Universitetas Plono elektrai laidaus permatomo grafeno sluoksnio gamybos būdas
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
US9744318B2 (en) 2011-12-16 2017-08-29 Novartis Ag Aerosolization apparatus for inhalation profile-independent drug delivery
WO2013114373A1 (en) 2012-02-01 2013-08-08 Protalix Ltd. Inhalable liquid formulations of dnase i
NZ629722A (en) 2012-02-29 2017-03-31 Pulmatrix Operating Co Inc Inhalable dry powders
DK3421042T3 (da) 2012-03-07 2024-07-22 Beyond Air Ltd Indånding af nitrogenoxid til behandling af luftvejssygdomme
CN106749272B (zh) 2012-03-13 2019-08-30 吉利德科学公司 用于抗病毒治疗的2’-取代的卡巴-核苷类似物
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
WO2014106056A2 (en) 2012-12-27 2014-07-03 Kaleo, Inc. Devices, systems and methods for locating and interacting with medicament delivery systems
GB201301192D0 (en) 2013-01-23 2013-03-06 Vectura Delivery Devices Ltd A blister piercing element for a dry powder inhaler
EP2964199B1 (en) 2013-03-04 2020-04-22 Besins Healthcare Luxembourg SARL Dry pharmaceutical compositions comprising active agent nanoparticles bound to carrier particles
CN104043104B (zh) 2013-03-15 2018-07-10 浙江创新生物有限公司 含盐酸万古霉素的喷雾干粉及其工业化制备方法
EP3587404B1 (en) 2013-03-15 2022-07-13 MannKind Corporation Microcrystalline diketopiperazine compositions, methods for preparation and use thereof
CA2907566C (en) 2013-04-01 2023-08-22 Pulmatrix, Inc. Tiotropium dry powders
CA2918369C (en) 2013-07-18 2021-06-29 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
WO2015012758A1 (en) * 2013-07-22 2015-01-29 Inhalation Sciences Sweden Ab Apparatus and method for generating an aerosol
CA3172586C (en) 2013-07-31 2025-10-14 Avalyn Pharma Inc. IMATINIB AEROSOL COMPOUNDS AND RELATED USES
EP3030294B1 (en) 2013-08-05 2020-10-07 MannKind Corporation Insufflation apparatus
KR102502328B1 (ko) 2013-08-20 2023-02-23 베링거잉겔하임베트메디카게엠베하 흡입기
ES2774735T3 (es) 2013-08-20 2020-07-22 Boehringer Ingelheim Vetmedica Gmbh Inhalador
AR097394A1 (es) 2013-08-20 2016-03-09 Boehringer Ingelheim Vetmedica Gmbh Inhalador
US12491325B2 (en) 2013-08-22 2025-12-09 Aptargroup, Inc. Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization for treatment of binge-eating disorders and/or obesity
DE202013105715U1 (de) * 2013-08-22 2014-02-19 Sipnose Ltd. Vorrichtung zur Abgabe einer vorbestimmten Menge einer Substanz an eine natürliche Öffnung des Körpers
US12329902B2 (en) 2013-08-22 2025-06-17 Sipnose Ltd. Drug delivery devices and methods for administering substances to a body cavity by heterogenous aerosolization
US11278682B2 (en) 2014-11-09 2022-03-22 Sipnose Ltd. Device and method for aerosolized delivery of substance to a natural orifice of the body
US11471618B2 (en) 2014-11-09 2022-10-18 Sipnose Ltd. Adjustable dosing delivery and multi sectioned drug compartment
US11116914B2 (en) 2014-11-09 2021-09-14 Sipnose Ltd. Device and method for aerosolized delivering of substance to a natural orifice of the body
US11992604B2 (en) 2014-11-09 2024-05-28 Sipnose Ltd. Devices and methods for delivering a substance to a body cavity
UA119050C2 (uk) 2013-11-11 2019-04-25 Ґілеад Саєнсиз, Інк. ПІРОЛО[1.2-f][1.2.4]ТРИАЗИНИ, ЯКІ ВИКОРИСТОВУЮТЬСЯ ДЛЯ ЛІКУВАННЯ РЕСПІРАТОРНО-СИНЦИТІАЛЬНИХ ВІРУСНИХ ІНФЕКЦІЙ
NZ722927A (en) 2014-01-10 2022-07-29 Avalyn Pharma Inc Aerosol pirfenidone and pyridone analog compounds and uses thereof
NO2709641T3 (oth) * 2014-03-10 2018-05-12
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
TWI678369B (zh) 2014-07-28 2019-12-01 美商基利科學股份有限公司 用於治療呼吸道合胞病毒感染之噻吩並[3,2-d]嘧啶、呋喃並[3,2-d]嘧啶及吡咯並[3,2-d]嘧啶化合物類
TWI673283B (zh) 2014-08-21 2019-10-01 美商基利科學股份有限公司 2’-氯胺基嘧啶酮及嘧啶二酮核苷類
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
US20170304459A1 (en) 2014-10-10 2017-10-26 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
WO2016115520A1 (en) 2015-01-16 2016-07-21 The J. David Gladstone Institutes Methods for treating tauopathy
CN107735135B (zh) 2015-04-02 2020-06-26 希尔-罗姆服务私人有限公司 用于呼吸装置的歧管
KR101722667B1 (ko) * 2015-06-02 2017-04-04 주식회사 포에버 흑채 자동분사기
AU2016311387B2 (en) 2015-08-25 2023-02-23 Babita Agrawal Immunomodulatory compositions and methods of use thereof
AU2017208857B2 (en) * 2016-01-19 2019-11-14 Novartis Ag Multidose inhaler
AU2017215189A1 (en) 2016-02-01 2018-08-02 Incarda Therapeutics, Inc. Combining electronic monitoring with inhaled pharmacological therapy to manage cardiac arrhythmias including atrial fibrillation
NL2017294B1 (en) 2016-08-05 2018-02-14 Univ Erasmus Med Ct Rotterdam Natural cryptic exon removal by pairs of antisense oligonucleotides.
WO2018116300A1 (en) * 2016-12-22 2018-06-28 Kamada Ltd. Dry powder formulations of alpha-1 antitrypsin
JP2020507841A (ja) 2017-01-17 2020-03-12 カレオ,インコーポレイテッド 無線接続及び事象検出を伴う薬剤送達デバイス
KR20200003199A (ko) 2017-05-10 2020-01-08 인카다 테라퓨틱스, 인크. 폐 투여에 의해 심장 병태를 치료하기 위한 단위 용량, 에어로졸, 키트 및 방법
NZ758839A (en) 2017-05-22 2025-08-29 Insmed Inc Glycopeptide derivative compounds and uses thereof
WO2019003216A1 (en) * 2017-06-29 2019-01-03 Sipnose Ltd. ADJUSTABLE DOSE ADMINISTRATION AND MULTI-SECTION MEDICINE COMPARTMENT
US10744087B2 (en) 2018-03-22 2020-08-18 Incarda Therapeutics, Inc. Method to slow ventricular rate
WO2020018433A1 (en) 2018-07-16 2020-01-23 Kaleo, Inc. Medicament delivery devices with wireless connectivity and compliance detection
BR112021021775A2 (pt) 2019-04-29 2022-01-04 Insmed Inc Composições de pó seco de pró-fármacos de treprostinil e métodos de uso destas
US11007185B2 (en) 2019-08-01 2021-05-18 Incarda Therapeutics, Inc. Antiarrhythmic formulation
PL4081305T3 (pl) 2019-12-24 2025-02-10 Carna Biosciences, Inc. Związki modulujące kinazę diacyloglicerolową
TWI775313B (zh) 2020-02-18 2022-08-21 美商基利科學股份有限公司 抗病毒化合物
TWI884403B (zh) 2020-02-18 2025-05-21 美商基利科學股份有限公司 抗病毒化合物
TWI794742B (zh) 2020-02-18 2023-03-01 美商基利科學股份有限公司 抗病毒化合物
JP7429799B2 (ja) 2020-02-18 2024-02-08 ギリアード サイエンシーズ, インコーポレイテッド 抗ウイルス化合物
CA3181922A1 (en) 2020-05-01 2021-11-04 Gilead Sciences, Inc. Cd73 inhibiting 2,4-dioxopyrimidine compounds
RS63995B1 (sr) * 2020-05-27 2023-03-31 Joozef Uređaj za inhaliranje supstance
EP4304582A1 (en) 2021-03-12 2024-01-17 Alvarius Pharmaceuticals Ltd. Compositions and methods for treating addictions comprising 5-meo-dmt
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
CN117396478A (zh) 2021-06-23 2024-01-12 吉利德科学公司 二酰基甘油激酶调节化合物
WO2022271684A1 (en) 2021-06-23 2022-12-29 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
JP7686086B2 (ja) 2021-06-23 2025-05-30 ギリアード サイエンシーズ, インコーポレイテッド ジアシルグリエルコール(diacylglyercol)キナーゼ調節化合物
EP4359411A1 (en) 2021-06-23 2024-05-01 Gilead Sciences, Inc. Diacylglyercol kinase modulating compounds
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof
MX2024005066A (es) 2021-10-29 2024-05-24 Gilead Sciences Inc Compuestos de cd73.
WO2023150747A1 (en) 2022-02-07 2023-08-10 Insmed Incorporated Dry powder compositions of bedaquiline and salts and methods of use thereof
KR102768557B1 (ko) * 2022-07-01 2025-02-17 주식회사 케이티앤지 인헤일러

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US478744A (en) * 1892-07-12 William james evans
US513189A (en) * 1894-01-23 Powder-blower
US2603216A (en) * 1952-07-15 Powder inhaler
US2307986A (en) * 1940-02-15 1943-01-12 Bolte Insufflator
US2533065A (en) * 1947-03-08 1950-12-05 George V Taplin Micropulverized therapeutic agents
US2570774A (en) * 1947-10-21 1951-10-09 Frank P C Davis Insufflator
US2549303A (en) * 1949-04-20 1951-04-17 Bristol Lab Inc Inhaler for crystalline pencilllin or the like
US3425600A (en) * 1966-08-11 1969-02-04 Abplanalp Robert H Pressurized powder dispensing device
US4069819A (en) * 1973-04-13 1978-01-24 Societa Farmaceutici S.P.A. Inhalation device
GB1479283A (en) * 1973-07-23 1977-07-13 Bespak Industries Ltd Inhaler for powdered medicament
IT1016489B (it) * 1974-03-18 1977-05-30 Isf Spa Inalatore
US3967761A (en) * 1974-04-08 1976-07-06 Southwest Research Institute System for injecting particulate material into the combustion chamber of a repetitive combustion coating apparatus
SU628930A1 (ru) * 1974-11-26 1978-10-25 Московский научно-исследовательский институт туберкулеза Устройство дл введени порошкообразного лекарственного вещества
GB1521000A (en) * 1975-06-13 1978-08-09 Syntex Puerto Rico Inc Inhalation device
US3994421A (en) * 1975-09-29 1976-11-30 American Cyanamid Company Unitary therapeutic aerosol dispenser
SE408265B (sv) * 1975-12-12 1979-06-05 Draco Ab Anordning for koldioxiddriven endosaerosol, avsedd for inhalering
NL7712041A (en) * 1977-11-01 1979-05-03 Handelmaatschappij Voorheen Be Suction equipment for powdery material - incorporates ejector type suction pump and cyclone type separator
DE2960616D1 (en) * 1978-05-03 1981-11-12 Fisons Plc Inhalation device
SU1003926A1 (ru) * 1979-01-24 1983-03-15 Всесоюзный Научно-Исследовательский И Конструкторский Институт Автогенного Машиностроения Порошковый питатель
IT1116047B (it) * 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma
WO1981001243A1 (en) * 1979-10-30 1981-05-14 Riker Laboratories Inc Breath actuated devices for administering powdered medicaments
IE56059B1 (en) * 1982-10-08 1991-04-10 Glaxo Group Ltd Devices for administering medicaments to patients
GB8314308D0 (en) * 1983-05-24 1983-06-29 Matburn Holdings Ltd Medical administration devices
DE3345722A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Inhalator
FR2575678B1 (fr) * 1985-01-04 1988-06-03 Saint Gobain Vitrage Ejecteur pneumatique de poudre
US4719263A (en) 1985-05-10 1988-01-12 The B. F. Goodrich Company Antistatic plastic materials containing epihalohydrin polymers
BE905189A (fr) * 1985-07-30 1987-01-29 Glaxo Group Ltd Dispositif pour administrer des medicaments a des patients.
IT1222509B (it) * 1987-08-17 1990-09-05 Miat Spa Insufflatore per la somministrazione di farmaci sotto forma di polvere predosata in opercoli
IT1217890B (it) * 1988-06-22 1990-03-30 Chiesi Farma Spa Dispositivo per l'inalazione di aerosol dosati
US4984158A (en) * 1988-10-14 1991-01-08 Hillsman Dean Metered dose inhaler biofeedback training and evaluation system
DK479189D0 (da) * 1989-01-06 1989-09-28 Hans Gernot Schenk Inhalator
IT1228459B (it) * 1989-02-23 1991-06-19 Phidea S R L Inalatore con svuotamento regolare e completo della capsula.
IT1230313B (it) * 1989-07-07 1991-10-18 Somova Spa Inalatore per medicamenti in capsule.
DE3927170A1 (de) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
ES2073736T3 (es) 1990-01-05 1995-08-16 Goodrich Co B F Polioxiranos de escaso peso molecular de cadenas prolongadas, destinados para aplicaciones electrostaticas.
US5201308A (en) * 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
IT1243344B (it) * 1990-07-16 1994-06-10 Promo Pack Sa Inalatore plurimonodose per medicamenti in polvere
US5037912A (en) * 1990-07-26 1991-08-06 The Goodyear Tire & Rubber Company Polymerization of 1,3-butadiene to trans-1,4-polybutadiene with organolithium and alkali metal alkoxide
GB9016789D0 (en) 1990-07-31 1990-09-12 Lilly Industries Ltd Medicament administering devices
US5217004A (en) * 1990-12-13 1993-06-08 Tenax Corporation Inhalation actuated dispensing apparatus
ES2284226T3 (es) 1991-07-02 2007-11-01 Nektar Therapeutics Dispositivo para proporcionar medicamentos en aerosol.
US5337740A (en) * 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
US5287850A (en) * 1991-08-20 1994-02-22 Habley Medical Technology Corporation Timing and velocity controlled powered pharmaceutical inhaler
GB9123953D0 (en) * 1991-11-12 1992-01-02 Minnesota Mining & Mfg Inhalation device
US5186166A (en) * 1992-03-04 1993-02-16 Riggs John H Powder nebulizer apparatus and method of nebulization
US5355872B1 (en) * 1992-03-04 1998-10-20 John H Riggs Low flow rate nebulizer apparatus and method of nebulization
WO1994008552A2 (en) * 1992-10-19 1994-04-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5290278A (en) 1992-10-20 1994-03-01 Proclosure Inc. Method and apparatus for applying thermal energy to luminal tissue
US5348995A (en) 1993-03-29 1994-09-20 Ppg Industries, Inc. Amine-free internal antistatic agent
US5533502A (en) * 1993-05-28 1996-07-09 Vortran Medical Technology, Inc. Powder inhaler with aerosolization occurring within each individual powder receptacle
US5349947A (en) * 1993-07-15 1994-09-27 Newhouse Michael T Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5505194A (en) * 1994-03-23 1996-04-09 Abbott Laboratories Aerosol inhalation device having slideably and rotatably connected elliptical cylinder portions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115666284A (zh) * 2020-05-27 2023-01-31 约瑟夫公司 用于吸入物质的装置

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US5740794A (en) 1998-04-21
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