TW208019B - - Google Patents

Info

Publication number
TW208019B
TW208019B TW079110518A TW79110518A TW208019B TW 208019 B TW208019 B TW 208019B TW 079110518 A TW079110518 A TW 079110518A TW 79110518 A TW79110518 A TW 79110518A TW 208019 B TW208019 B TW 208019B
Authority
TW
Taiwan
Prior art keywords
ch2c6h5
doxorubicin
chem
branched
linear
Prior art date
Application number
TW079110518A
Other languages
English (en)
Chinese (zh)
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898928654A external-priority patent/GB8928654D0/en
Priority claimed from GB909007513A external-priority patent/GB9007513D0/en
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Application granted granted Critical
Publication of TW208019B publication Critical patent/TW208019B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/30—Compounds having groups
    • C07C43/313—Compounds having groups containing halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
TW079110518A 1989-12-19 1990-12-14 TW208019B (show.php)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898928654A GB8928654D0 (en) 1989-12-19 1989-12-19 Preparation of 2-methoxy-4-morpholinyl anthracyclines
GB909007513A GB9007513D0 (en) 1990-04-03 1990-04-03 Morpholinyl derivatives of doxorubicin and process for their preparation

Publications (1)

Publication Number Publication Date
TW208019B true TW208019B (show.php) 1993-06-21

Family

ID=26296395

Family Applications (1)

Application Number Title Priority Date Filing Date
TW079110518A TW208019B (show.php) 1989-12-19 1990-12-14

Country Status (28)

Country Link
EP (1) EP0434960B1 (show.php)
JP (1) JP3300342B2 (show.php)
KR (1) KR0183033B1 (show.php)
CN (2) CN1024922C (show.php)
AT (1) ATE143023T1 (show.php)
AU (1) AU636429B2 (show.php)
CA (1) CA2046857C (show.php)
CZ (1) CZ281949B6 (show.php)
DE (1) DE69028610T2 (show.php)
DK (1) DK0434960T3 (show.php)
ES (1) ES2094136T3 (show.php)
FI (1) FI97389C (show.php)
GR (1) GR3021557T3 (show.php)
HR (1) HRP921226B1 (show.php)
HU (2) HU209433B (show.php)
IE (1) IE81174B1 (show.php)
IL (3) IL111527A (show.php)
MY (1) MY119192A (show.php)
NO (2) NO175533C (show.php)
NZ (1) NZ243695A (show.php)
PT (1) PT96226B (show.php)
RU (1) RU2100366C1 (show.php)
SI (1) SI9012379B (show.php)
SK (1) SK278994B6 (show.php)
TW (1) TW208019B (show.php)
UA (1) UA27108A1 (show.php)
WO (1) WO1991009046A1 (show.php)
YU (1) YU48136B (show.php)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843903A (en) * 1995-11-27 1998-12-01 The Administrators Of The Tulane Educational Fund Targeted cytotoxic anthracycline analogs
AU767394C (en) * 1999-12-29 2005-04-21 Immunogen, Inc. Cytotoxic agents comprising modified doxorubicins and daunorubicins and their therapeutic use
CN101134119A (zh) 2002-05-24 2008-03-05 血管技术国际股份公司 用于涂覆医用植入物的组合物和方法
AU2003275263A1 (en) 2002-09-26 2004-04-19 Angiotech International Ag Perivascular wraps
WO2004060346A2 (en) 2002-12-30 2004-07-22 Angiotech International Ag Drug delivery from rapid gelling polymer composition
MXPA05009849A (es) * 2003-03-18 2005-12-06 Pharmacia Italia Spa Terapia combinada que comprende nemorubicina y un inhibidor de la ciclooxigenasa-2.
CA2658146A1 (en) * 2006-07-12 2008-01-17 Nerviano Medical Sciences S.R.L. Crystalline nemorubicin hydrochloride
EP2277884B1 (en) * 2008-04-11 2017-08-23 Tianjin Hemay Oncology Pharmaceutical Co., Ltd Anthracycline antibiotic derivatives with high activity, preparation methods and uses thereof
CN101353361B (zh) * 2008-08-08 2011-06-01 中国人民解放军第四军医大学 一种阿霉素前体药物的制备方法及其应用
EP2646456B1 (en) * 2010-12-02 2015-01-21 Nerviano Medical Sciences S.r.l. Process for the preparation of morpholinyl anthracycline derivatives
CN105164138B (zh) 2013-04-29 2017-11-07 内尔维阿诺医学科学有限公司 新吗啉基蒽环类抗生素衍生物
WO2015089268A1 (en) 2013-12-11 2015-06-18 University Of Massachusetts Compositions and methods for treating disease using salmonella t3ss effector protein (sipa)
RU2715902C2 (ru) 2014-11-05 2020-03-04 НЕРВИАНО МЕДИКАЛ САЙЕНСИЗ С.р.л. Функционализированные производные морфолинилантрациклина
CN115043895A (zh) * 2022-07-15 2022-09-13 戊言医药科技（上海）有限公司 一种pnu-159682及其中间体的制备方法
EP4572798A1 (en) * 2022-08-15 2025-06-25 Synaffix B.V. Anthracyclins and conjugates thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2883443A (en) * 1956-07-13 1959-04-21 Ruetschi Karl Lead-acid storage battery
US4423123A (en) * 1980-04-17 1983-12-27 Shin-Kobe Electric Machinery Co., Ltd. Electric storage battery and a method of making the same
JPS57163393A (en) * 1981-03-27 1982-10-07 Microbial Chem Res Found Novel anthracyclin derivative and its preparation
US4363857A (en) * 1981-10-16 1982-12-14 General Motors Corporation Laminated metal-plastic battery grid
US4710564A (en) * 1985-01-18 1987-12-01 Microbial Chemistry Research Foundation Anthracycline compounds
GB2172594B (en) * 1985-03-22 1988-06-08 Erba Farmitalia New morpholino derivatives of daunorubicin and doxorubicin
JPS6215323A (ja) * 1986-02-14 1987-01-23 Dainippon Ink & Chem Inc 微多孔中空繊維の製造法
US4861836A (en) * 1986-12-23 1989-08-29 Daikin Industries Ltd. Novel, iodine-containing compound, preparation thereof and block copolymer comprising the same

Also Published As

Publication number Publication date
CA2046857A1 (en) 1991-06-20
SI9012379B (sl) 2000-02-29
FI913887A0 (fi) 1991-08-16
CZ281949B6 (cs) 1997-04-16
HUT60232A (en) 1992-08-28
UA27108A1 (uk) 2000-02-28
SI9012379A (en) 1997-12-31
NO913176D0 (no) 1991-08-14
NZ243695A (en) 1993-06-25
NO940831L (no) 1991-08-14
IL111527A (en) 1998-02-22
CA2046857C (en) 2001-06-12
NO175533C (no) 1994-10-26
ATE143023T1 (de) 1996-10-15
HUT59693A (en) 1992-06-29
AU636429B2 (en) 1993-04-29
NO175533B (no) 1994-07-18
IL111527A0 (en) 1995-01-24
DE69028610D1 (de) 1996-10-24
WO1991009046A1 (en) 1991-06-27
HRP921226B1 (en) 1998-10-31
YU48136B (sh) 1997-05-28
CZ621990A3 (en) 1997-01-15
HU208148B (en) 1993-08-30
KR920701228A (ko) 1992-08-11
CN1053238A (zh) 1991-07-24
EP0434960A1 (en) 1991-07-03
SK621990A3 (en) 1998-05-06
PT96226B (pt) 1998-06-30
HRP921226A2 (en) 1995-12-31
PT96226A (pt) 1991-09-30
CN1039708C (zh) 1998-09-09
NO913176L (no) 1991-08-14
NO176911C (no) 1995-06-21
HU9200656D0 (en) 1992-05-28
CN1024922C (zh) 1994-06-08
IL96643A (en) 1995-01-24
AU6919491A (en) 1991-07-18
GR3021557T3 (en) 1997-02-28
IL96643A0 (en) 1991-09-16
NO176911B (no) 1995-03-13
CN1079215A (zh) 1993-12-08
RU2100366C1 (ru) 1997-12-27
HU209433B (en) 1994-06-28
MY119192A (en) 2005-04-30
DE69028610T2 (de) 1997-02-06
DK0434960T3 (da) 1996-10-14
YU237990A (sh) 1993-05-28
NO940831D0 (no) 1994-03-09
EP0434960B1 (en) 1996-09-18
JPH04503679A (ja) 1992-07-02
IE81174B1 (en) 2000-06-14
FI97389B (fi) 1996-08-30
HU912994D0 (en) 1992-01-28
IE904543A1 (en) 1991-06-19
JP3300342B2 (ja) 2002-07-08
KR0183033B1 (ko) 1999-04-01
FI97389C (fi) 1996-12-10
SK278994B6 (sk) 1998-05-06
ES2094136T3 (es) 1997-01-16

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