TW201016253A - Modular, reduced-pressure, wound-closure systems and methods - Google Patents

Modular, reduced-pressure, wound-closure systems and methods Download PDF

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TW201016253A
TW201016253A TW098116475A TW98116475A TW201016253A TW 201016253 A TW201016253 A TW 201016253A TW 098116475 A TW098116475 A TW 098116475A TW 98116475 A TW98116475 A TW 98116475A TW 201016253 A TW201016253 A TW 201016253A
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TW098116475A
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Keith Patrick Heaton
Ian James Hardman
Christopher Guy Coward
Colin John Hall
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Kci Licensing Inc
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Publication of TW201016253A publication Critical patent/TW201016253A/zh

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/96—Suction control thereof
    • A61M1/964—Suction control thereof having venting means on or near the dressing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/00987—Apparatus or processes for manufacturing non-adhesive dressings or bandages
    • A61F13/01025—
    • A61F13/01034—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive plasters or dressings
    • A61F13/05—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/91—Suction aspects of the dressing
    • A61M1/912—Connectors between dressing and drainage tube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/91—Suction aspects of the dressing
    • A61M1/915—Constructional details of the pressure distribution manifold
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/91—Suction aspects of the dressing
    • A61M1/916—Suction aspects of the dressing specially adapted for deep wounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00—Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00575—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect for closure at remote site, e.g. closing atrial septum defects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00646—Type of implements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/0057—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect
    • A61B2017/00676—Implements for plugging an opening in the wall of a hollow or tubular organ, e.g. for sealing a vessel puncture or closing a cardiac septal defect promotion of self-sealing of the puncture
    • A61F13/01029—
    • A61F13/01038—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/90—Negative pressure wound therapy devices, i.e. devices for applying suction to a wound to promote healing, e.g. including a vacuum dressing
    • A61M1/98—Containers specifically adapted for negative pressure wound therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00—Anatomical parts of the body
    • A61M2210/10—Trunk
    • A61M2210/1021—Abdominal cavity
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor
    • Y10T156/1052—Methods of surface bonding and/or assembly therefor with cutting, punching, tearing or severing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor
    • Y10T156/1052—Methods of surface bonding and/or assembly therefor with cutting, punching, tearing or severing
    • Y10T156/1056—Perforating lamina
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor
    • Y10T156/1052—Methods of surface bonding and/or assembly therefor with cutting, punching, tearing or severing
    • Y10T156/1056—Perforating lamina
    • Y10T156/1057—Subsequent to assembly of laminae
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/10—Methods of surface bonding and/or assembly therefor
    • Y10T156/1052—Methods of surface bonding and/or assembly therefor with cutting, punching, tearing or severing
    • Y10T156/1062—Prior to assembly
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T156/00—Adhesive bonding and miscellaneous chemical manufacture
    • Y10T156/12—Surface bonding means and/or assembly means with cutting, punching, piercing, severing or tearing
    • Y10T156/1304—Means making hole or aperture in part to be laminated
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T29/00—Metal working
    • Y10T29/49—Method of mechanical manufacture
    • Y10T29/49826—Assembling or joining

Description

201016253 六、發明說明： 【發明所屬之技術領域】 本發明整體而言係關於醫療治療系統，且更特定而言係 關於減壓、傷口閉合及治療系統與方法。 本發明根據美國專利法35 U.S.C. § 119(e)規定主張2008 年 10 月 29 日申請之名稱為「1^(11106£1-?犷6581^6,\\/〇1111(1-Closure System and Method」之美國臨時專利申請案第 61/109,410號；2008年10月29日申請之名稱為「Reduced-Pressure, Abdominal Treatment System and Method」之美 國臨時專利申請案第61/109,486號；名稱為「Open-Cavity, Reduced-Pressure Wound Dressing and System」之美國臨 時專利申請案第61/109,390號；及2008年10月29日申請之 名稱為「Reduced-Pressure, Deep-Tissue Closure System and Method」之美國臨時專利申請案第61/109,448號之權 益。所有該等臨時申請案皆出於所有目的以引用方式併入 本文中。 【先前技術】 不論一傷口或組織受損區域之病原為外傷、外科手術或 其他原因，適當的照護該傷口對最後結果係很重要的。當 該傷口牽涉到諸如腹膜腔且更一般而言係腹腔之需要再進 入之位置時，便存在特別的挑戰。很多時候，當外科手術 或外傷牽涉到腹腔時，建立一有助於再進入之傷口管理系 統係可使照護更完善且更容易，並且有助於改善諸如腹膜 炎、腹室併發症（ACS)以及可能會妨礙到傷口及内部器官 140509.doc 201016253 最好可從該腔 最終疾癒之感染等情況。在提供此照護時 移除不當的流體，有助於接近筋膜及其他組織，或者最後 有助於在傷口本身上面於表皮層處提供閉合力。除非另有 指明’否則在本文中所用之「或」字並不一定表示互斥 性。 目前’在表皮上之一腹部開口可利用縫合線、u形釘、 夾具及其他機械裝置來使得皮膚可被固定及拉開。此等裝
置通常會造成刺破性傷口或造成其他傷口。再者，若發生 嚴重浮腫’則在該閉合裝置上會形成巨大的壓力且該壓力 可能會造成傷害。例如，若該壓力由於浮腫而上升，則可 能造成縫合線斷裂。 統，已有發展出許多 中且然後利用諸如上 針對可允許再進入至腹腔之整體系 技術。一種手段係將毛巾置入至該腔 血鉗之夾具來將皮膚密合於該等毛巾上。雖然簡單且快 速’但其結果係被視為非完美的。另一手段係所謂的 「Bogota袋」。就此手段而言，一袋係被縫合至定位以覆 蓋敞開的腹部來提供一屏障。有時被稱之為 vac pack j 之另-手段係將毛巾塞人傷口且㈣將—引流管置入復部 中並以一敷巾覆蓋該腹部。最後，已有採用一減壓手段。 此一手段係揭示在H u n t等人讓渡給美國德州聖安東尼奥内 之KCI Licensing公司之美國專利第7,381，859號中。該美國 專利第7,381，859號出於所有目的以引用方式併入本文中。 【發明内容】 既有之傷口閉合裝置及減壓治療系統所存在的問題係可 140509.doc 201016253 二文中所述之說明性實施例的系統、設備及方法來 依照—說明性實施例，-模組式減麼、傷口閉 個連接二構件、複數個附接基部構件及複數 複數個連接構件〆以开^ 部構件係可移動地轉接至該 收縮構件係可摔作二界定一内部空間之圓周壁部。該 依照另-==:置在該:部空… 表面傷口上產生=種製造—用於在-患者之- ❹ 方法係包括形成二::::式::、傷口閉合系統之 件且形成複數個連接構=、：成複數個附_ 及該複數複數個附接基部構件 定-㈣空::::::操……接來形成-界
依月?、另 說明j 生眚# /s I 者之—表面傷口 二Γ以提供一閉合力於一患 Φ 供複數個附接基部構件之步:括收縮構件及提 基部及-第-壁部，該第一壁部::::=件具有-端部。該第-壁部之第-端部包括一第：：及第-該第二端部包括—第二可動連接構件第:可=構件且 係用於可釋放地附接至一患者的表皮之讀基部構件 至該密封收縮構件。該用以產生 。刀且用於輕接 括提供複數個連接構件。該複數個二 件包括一第二壁部，該第連接構 端部。該第二壁部之該第1部丄二=及-第二 一壁部之該第二端部具有-第上::::構： 140509.doc 201016253
接構件係用於可移動地麵接至該複數個附接基部構件 中之兩個。該用以產生一閉合力之方法係進一步包括提供 減麼至該密封收縮構件。該提供-閉合力之方法進—步包 括可移動_接該複數個附接基部構件及該複數個連接構 件以开v成界疋一内部空間之圓周壁部。該提供一閉合力 之方法係進-步包括將該密封收縮構件安置在該内部空間 中且供應減壓至該收縮構件，藉此產生一力量來將該等附 接基部構件向内拉攏以在該表面傷口上產生一閉合力。 依照另一說明性實施例，一種用以提供一閉合力於—患 者之表面知口上且用以輸送減壓至一組織部位之減壓、 傷口閉合及治療系統係包括一傷口閉纟子系統及一減壓治 療子系統。 參照圖式及以下實施方式之說明，將可對該等說明性實 施例之其他目的、特徵及優點有更深入之瞭解。 【實施方式】 在說明性實施例之以下實施方式中，參照形成其一部分 之附圖。為使得熟習此項技術者能夠實踐本發明而足夠詳 細地描述此等實施例，且應理解，可利用其他實施例且可 作出邏輯結構性、機械性、電氣及化學改變，而不背離本 發明之精神或範疇。為避免為使得熟習此項技術者能夠實 踐本文中所述實施例所不需要之細節，本描述可省略熟習 此項技術者已知之某一資sfl。因此，不應將以下實施方式 視為具有限制意義，立該等說明性實施例之範_僅由隨附 申請專利範圍界定。 140509.doc 201016253 請參考圖1-2,且首先參考圖丨，其中顯示一減壓、傷口 閉合及治療系統100之一說明性實施例。該減壓、傷口閉 合及治療系統1 00可包括一減壓治療子系統丨〇2及一傷口閉 合子系統104。該減壓治療子系統1〇2可用於以減壓來治療 一組織部位106。該組織部位1〇6可以係任何人類、動物或 其他生物之身體組織，包括骨骼組織、脂肪組織、肌肉組 織、真皮組織、血管組織、結締組織、軟骨、肌腱、韌帶 或任何其他組織。該組織部位1〇6可位在一體腔中，諸如 腹腔110，且可包括各種不同組織層，包括在表皮1〇8中 之一傷口。藉由減壓治療子系統102之治療可包括移除流 體，諸如腹水或分泌物、輸送減壓或提供一保護性屏障。 在該說明性實施例中，該減壓、傷口閉合及治療系統 100係以該腹腔110及一具有傷口邊緣112之表面傷口 U1的 内容來呈現。其他的皮下組織i 14亦可被打開，諸如脂肪 組織 '肌肉、筋膜等等。該腹腔11〇如圖所示係具有腹部 内容物116’其形成一表面或支撐件。 該減Μ、傷口閉合及治療系統100之減壓治療子系統1 〇2 有助於將減壓輸送至該組織部位106及該腹腔11〇 ^該減壓 治療子系統102包括一被安置在該腹腔丨丨〇中之歧管1丨8以 分佈該腹腔110内之減壓且接收流體。該歧管u 8可包括— 歧管構件120或與該歧管構件相聯結，或者在一非黏性封 套122中之第二歧管。該非黏性封套122具有位在一第—側 上之孔隙124及位在一第二、面向内（面向組織）側上之孔隙 126 °該等孔隙124及ι26有助於使流體如箭頭128所示般流 140509.doc •10· 201016253 動。該等孔隙124及126可採用任何形狀，諸如長方形開 口、圓形開口、多邊形、狭縫（長形凹槽）等等。該非黏性 封套122可由可撓性薄膜所形成，諸如一聚胺基▼酸輯薄 膜、一敷巾材料或任何非黏性材料。 . 減壓可藉由該減壓治療子系統1〇2而供應至該腹腔11〇及 、 該組織部位106以有助於促進分泌物、腹水或其他液體、 細菌、纖維蛋白、壞死組織、毒素、殘留血液等等之移 Φ 除。減壓亦可在特定情況中來使用以刺激額外組織之生 長。在該組織部位106處具有一傷口的情況下，粒狀組織 之生長及分泌物與細菌之移除係有助於促進傷口之痊癒。 在一非傷口性或非缺陷性組織的情況中，減壓可用以促進 可被收成且移植至其他組織部位之組織的生長。在其他情 況中’流體移除可能係施加減壓之最主要理由。 在本文中所用之「減壓」泛指小於在該組織部位丨06處 之周圍壓力的壓力。在大部分情況中，該減壓係小於患者 Φ 所在位置處之大氣壓力。或者，該減壓可小於該組織部位 106之流體靜力壓力。除非另有指明，否則在本文中所陳 述之壓力值係計示壓力。 該歧管118與歧管構件120被安置在腹腔110中且可被安 置在或靠近於該組織部位106。典型而言，容納該歧管構 件120之該非黏性封套122係被安置成抵靠該組織部位 106 ’且詳言之，係靠近該腹部内容物116。該歧管118被 安置成相鄰於該非黏性封套122。該歧管118及該歧管構件 120可知用許多形式。在本文中所用之術語「歧管」係指 140509.doc 201016253 一被提供用以輔助施加減壓至、輸送流體至一組織部位 (諸如該組織部位1 06)或自該組織部位移除流體之物質或結 構。該歧管11 8及該歧管構件120 —般包括複數個流動通道 或通路’其等係互連以增進被提供至靠近該歧管U8及歧 管構件120處之區域或欲自該區域移除之流體的分佈。該 歧管118及歧管構件120可由一生物相容性材料來形成，該 材料係可被放置成與組織相接觸且可分佈減壓。歧管之實 例可包括（但不限於）具有經配置以形成流動通道之結構性 元件的裝置、諸如開放氣室發泡體之多孔性發泡體、多孔 性組織集合’以及包括或固化以包括流動通道之液體、凝 膠及發泡體。 該歧管118及該歧管構件120可以係多孔性且可由發泡 體、薄紗、氈製墊或適於一特定生物應用之任何其他材 料。在一實施例中’該歧管118及歧管構件120係由一多孔 性發泡體所製成，其包括複數個用以作為流動通道之互連 氣室或細孔。該多孔性發泡體可以係一聚胺基甲酸酯、開 放氣室、網狀發泡體，諸如由美國德州聖安東尼奥市之
Kinetic Concepts公司所製造之GranuFoam®材料。其他實 施例可包括在特定位置處「封閉氣室」以有助於導引流 動。在某些情況中，該歧管118、歧管構件12〇及非黏性封 套122可用以分佈流體（諸如藥物、抗菌劑、生長因子及其 他溶液）至該組織部位1〇6。其他層體可被包括作為該歧管 118或歧管構件12〇之部分，諸如吸收性材料、毛細作用材 料、疏水性材料及親水性材料。 140509.doc •12- 201016253 一密封構件132可放置在表皮1〇8中之表面傷口上，且詳 言之，其係經製造用以覆蓋該傷口邊緣112以提供一氣動 式密封。因此，該密封構件132在歧管118及非黏性封套 122上提供—密封。該密封構件132可以係一罩蓋，其用以 . 將歧管U8與非黏性封套122牢固於該組織部位1〇6。雖然 該密封構件132可以係不滲透性或半滲透性，然而該密封 構件132可在將密封構件132安裝在該歧管118上之後於該 φ 組織部位106處維持一減壓。該密封構件132可以係一可撓 性上覆式敷巾或薄膜，其係由聚矽氧基化合物、丙稀酸、 水凝膠或水凝膠構成材料或者係包括不滲透性或針對特定 組織部位所需要之滲透性特性之任何其他生物相容性材料 所製成。 該密封構件132可進一步包括一用以將該密封構件Η〗牢 固至該患者的表皮108之附接裝置136。該附接裝置136可 採用任何形式；例如，可使用一密封帶或一黏膠Η#可沿 • 該密封構件13 2之一周邊或該密封構件13 2之任何部分而定 位以提供一氣動式密封。該黏膠134亦可預先施加且覆蓋 一在施加後可被移除之可釋放構件（未圖示）。 一第一減壓界面138或治療減壓界面（諸如一埠口 14〇或 連接益）可用以將減壓從一第一減壓輸送導管142輸送至該 歧笞118且至a亥第—減壓界面138。該歧管亦可將任何 分泌物、腹水或其他流體從該第一減壓輸送導管142輸送 至該歧官118。在該箭頭144中之減壓將該流體沿第一減壓 輸送導管142所示之方向拉引至該第一減壓界面138。讓歧 140509.doc •13· 201016253 管118允許流體從該第一減壓輸送導管142通往組織部位 106。例如，利用該歧管11 8所收集來自於該歧管構件j 2 〇 之流體係可經由該第一減壓界面138而進入第一減壓輸送 導管142。在另一實施例中’該減壓治療子系統1 〇2可排除 該第一減壓界面138,且該第一減壓輸送導管142可直接插 入至該密封構件132及該歧管118中。該第一減壓輸送導管 142可以係一醫療導管、多内腔式構件、管件或用以輸送 一減壓之任何其他構件。 一減壓子系統14 8可用以供應被輸送至該第一減壓輸送 導管142之減壓。該減壓子系統148可包括一第一減壓單元 或源150，其輸送減壓至一導管152，該供應導管則係輸送 減壓至一三通閥154。該減壓之一部分可經由一第二減壓 輸送導官1 56而離開該三通閥丨54。該減壓之另一部分則可 經由一減壓導管158而離開該三通閥154。許多裝置（諸如 一減壓反饋單元160)被定位在該減壓導管158上，其可例 如給予該三通閥154有關於在該減壓導管158中之該減壓之 調節有關的反饋。該減壓導管158輸送該減壓至一罐子 162，該罐子係可操作以容置從該組織部位1〇6被輸送至該 罐子162之任何流體。離開該罐子162之減壓被輸送至該第 減壓輸送導官142。該第一減壓輸送導管142可被指稱為 輸送一第二減壓或治療減壓，因為其中之該減壓已藉由該 減壓子系統148而處在用於在該組織部位1〇6處之減壓治療 時使用之適备壓力及之條件下。被輸送至該第一減壓輸送 導管142之減壓通常係經選擇而在該組織部位處為_5〇 140509.doc 201016253
Hg至-500 mm Hg的範圍内 及-300 mm Hg之間。 且更典型地為-100 mm Hg 許多個不同的裝置，例如 — 幻如代表性裝置166，可被增添至 該第一減壓輸送導管. α 之一中間部分164。該代表性裝置 166可以係一壓力反饋奘 、 謂裒置 '一體積偵測系統、一血液偵 測系統、一感染偵測系統、_、ά /;IL動jul視系統、一溫度監視 系統等等。〇!縣置之某些可與其他部分—體成形；例
如，該罐子162可包括_或多個過濾$，例如—用以防止 液體離開之疏水性過濾器。 已有許多方法來形成可使用於該減壓、傷π閉合及治療 系統100之減壓。在如圖所示之說明性實施例中，該第一 ㈣單元15G係可兼用於傷口閉合及㈣治療之應用。在 -替代形式之實施例中，其適當地使用該第一減壓單元 150作為用於該第二減麼輪送導管156之源且具有一第二減 壓皁元1 5 1 (以虛線表示）以輪送減壓至該減壓導管丨5 8。 作為該減壓、傷口閉合及治療系統刚之一態樣，其最 好有助於提供一閉合力至該表面傷口m，且更具體而 言，係施加-閉合力於該等傷口邊緣112之間。如圖"斤 不’該傷口閉合子系統104可用於此一目的。該傷口閉合 子系統104形成-由箭頭m所表示之閉合力。該閉合力: 傳達至該表皮1G8且使該等傷口邊緣112朝向彼此趨合。該 傷口閉合子系統104可以係一用於閉合任何表面傷口（獨 立系統或可用以作為—較大系統（例如該減壓、傷口閉人 及治療系統100)之一部分。 ° 140509.doc -15- 201016253 該傷口閉合子系統1G4可包括複數個附接基部構件，例 如-第一附接基部構件172及一第二附接基部構細。該 等附接基部構件之每—者可移動地㈣—連接構件（類似 於以下圖3中之第—連接構件326)以形成_具有—内部空 間（類似於以下圖5A中之内部空間381)之圓周壁部（類似: 以下圖5A中之圓周壁部38〇)。一密封收縮構件⑽被安置 在内部空間中且輕接至該等附接基部構件之至少兩個，例 如第：附接基部構件172及第二附接基部構件184。該圓周 參 壁部係可操作以隨著該密封收縮構件188收縮而撓曲或移 動0 該第一附接基部構件〗72具有一第一基部174及一第一壁 部176。該第-基部m具有一第一側m及一第二、面= 内側180。該第一基部m及第一壁部176可由多種材料所 製成’但最好係可提供可撓性之材料；例如，形成有該第 一基部174及該第一壁部176之該第—附接基部構件】可 以由聚丙烯或一硬質聚矽氧等等所製成。—第一黏膠Μ) 可被施加至第一基部174之第二、面向内側18〇，以使得該 · 第一基部174係可釋放地直接附接至該患者的表皮ι〇8之一 部分或者若-聚胺基f酸醋薄膜或另—密封構件132純 置放在該表皮108上則便間接地附接。除了第一黏膠M2以 外，U形釘或縫合線，或者其他侵入性手段在某些情況中 可用以將該第一基部174附接至完好的表皮組織。該第一 附接基部構件172可直接施加在表皮1〇8之頂部或密封構件 132之頂部，使得被施加在該第一附接基部構件上之閉 I40509.doc •16- 201016253 口力都可被直接或間接地傳送至該表皮丨〇8。所謂施加該 第一附接基部構件丨7 2至表皮丨〇 8應視為包括施加在該密封 構件132上。該第一附接基部構件174可包括一可動連接構 件175，其經定大小且經構形以與另一可動連接構件（例如 在圖3中之第三可動連接構件334)相配接，及一第二減壓 界面177(或閉合減壓界面），其有助於減壓輸送至該密封收 縮構件188。 φ 該第二附接基部構件184係類似於第一附接基部構件 !72’除了該第二附接基部構件184並未包括該第二減壓界 面177。该第二附接基部構件184具有一基部及一壁部 1 87。雖然該傷口閉合子系統1〇4在圖中僅顯示兩個附接基 4構件1 72、1 84，但其他的附接構件能以在其間具有連接 構件之間隔方式散佈於表面傷口 i i i周圍，以圍繞該表面 傷口 111形成該圓周壁部。該附接基部構件(例如附接基部 構件172、184)結合該密封收縮構件188係允許由箭頭 籲戶斤表不之。亥閉合力可橫越該表面傷口⑴之不同形狀來產 生。 該等附接基部構件之—或多個（例如，附接基部構件 m)具有用以接收來自於該第二減壓輸送導管⑼之減壓 的第二減壓界面177。經由第二減壓界面177所輸送之減壓 係用以產生邊閉合力。在該第二減壓輸送導管中之該 減壓（或閉口減壓）可經選擇而落在-⑽腿取至丄剛mm Hg的範圍中。 該傷口閉合子系統1 04 6 k m τ包括用以產生該閉合力之密封收 140509.doc 201016253 縮構件188。該密封收縮構件1 88可由一收縮歧管材料或構 件所形成，其可以與該歧管11 8為相同類型的材料。或 者’其可適當地使用一收縮歧管材料，其具有比用於歧管 118之材料還要少的孔隙或細孔。此外，可適當地具有一 材料，其在垂直方向（針對圖1所示之定向）具有較少的收縮 性且在水平或橫向平面（針對圖1所示之定向）具有較多的收 縮性，亦即’ 一異向性材料。該密封收縮構件1 88具有_ 第一側190及一第二、面内（面向組織）側192。 該密封收縮構件1 8 8亦具有一周緣邊緣丨94。該密封收縮 霉 構件1 88可藉由使一第一密封構件j96施加至該密封收縮構 件188之該第一側190且使一第二密封構件198施加至該第 一、面内（面向組織）側1 92而被密封。該密封收縮構件〗88 之周緣邊緣194可藉由一周緣密封構件2〇〇予以密封。替代 地或額外地，該第一壁部構件176亦可用以作為該周緣密 封構件以密封周緣邊緣i 94或者可使用其他的密封材料 件。同樣地，該第二、面内（面向組織）侧192亦可藉由置靠 於密封構件U2或患者的表皮1〇8上而被予密封。該密封收 _ 縮構件188亦可藉由塗覆一不透氣材料而被密封。該密封 收縮構件188可藉由第一及第二密封構件196、198予以密 . 封’該等密封構件係由一聚胺基甲酸酯薄膜或聚矽氧所形 成。該第-及第二密封構件196、携可在其兩端部予以肖 · 音波熔接或RF熔接以覆蓋該周緣邊緣194。當減麼被供應 至該密封收縮構件188時，該密封收縮構件188會收縮以產 生-由箭頭170所表示之閉合力。該密封收縮構件188在該 140509.doc •】8- 201016253 密封收縮構件188之一部分上可形成有一開口 2〇1，以接收 該第減壓界面138之一延伸部分202。該延伸部分202可 延伸通過該密封收縮構件188且進入至該歧管Π8中。 在操作時，該減壓傷口閉合及治療系統1〇〇可藉由首先 • 施加一歧管材料在該腹部内容物U6上而使用在一禮腔 中，例如腹腔110。例如，具有非黏性封套122之歧管搆件 120可放置在該腹部内容物116上且該歧管118被安置成靠 Φ 近該非黏性封套122。該表面傷口 111之傷口邊緣112係儘 可旎的的程度攏合在一起，且然後該密封構件132被放置 在表皮108上以在表面傷口 lu上提供一氣動式密封。該第 一附接構件172可利用第一黏膠182而施加至患者的表皮 108上或在密封構件132上。然後，連接構件及附接構件可 被安置於該表面傷口 111之周圍。該附接構件（例如，第一 及第二附接基部構件172、184)係耦接至該患者的表皮 1〇8(或密封構件）且該密封收縮構件188被耦接至該附接構 φ 件（例如，第一及第二附接基部構件172、184)。在附接構 件（例如’第一及第二附接基部構件172、184)與該密纣收 縮構件188之間的此一耦接係能以多種不同方式來達成， 諸如藉由使用黏膠189及191。 可以作為該減壓埠口 140之第一減壓界面138可被應用而 使得一延伸部分202伸入至該歧管118中。該第一減壓輪送 導管142可被耦接至該第一減壓界面138以提供與該第—減 壓單元150(或一可選擇的第二減壓單元151)之一流體式輛 接。該第二減壓輸送導管156可流體式地耦接至該第二減 140509.doc -19· 201016253 壓界面177。 該減壓、傷口閉合系統1 〇〇被啟動而使得第一減壓單元 150輸送減壓通過該三通閥154，該三通閥準備好欲被輪送 至該第一減壓輸送導管142之治療減壓，以及欲被輸送至 該第二減壓輸送導管156之一閉合減壓.治療減壓係經由 該第一減壓輸送導管142而被輸送且在該歧管U8處被實 現，該歧管係拉引由箭頭144及128所標示之流體且分佈減 壓於該腹腔110中。在此同時，經由第二減壓輸送導管156 所輸送之該閉合減壓係經由密封收縮構件1 88所實現，其 造成密封收縮構件188收縮而產生由箭頭17〇所表示之該閉 合力。該閉合力將第一及第二附接基部構件172、184朝向 彼此拉擺在一起且藉此拉攏該等傷口邊緣112。在某些應 用中，該減壓、傷口閉合治療系統1〇〇可單獨使用以閉合 一傷口。 現請參考圖2至5B，其中顯示一模組式減壓、傷口閉合 系統300之一部分。該模組式減壓、傷口閉合系統3〇〇係使 用許多模組式組件，其等被可移動地耦接在一起以配合各 種不同傷口之大小及形狀且用以提供一指向該傷口之一中 心之閉合力’亦即將該等傷口邊緣推靠在一起之閉合力。 使用模組式組件允許適用於多種表面傷口之大小及形狀而 不需要大量不同大小及形狀之傷口敷料或裝置的庫存。 首先請參考圖2，可使用複數個附接基部構件，諸如第 一附接基部構件302。每一附接基部構件302具有一基部 3〇4，其具有一第一側306及一第二、面内（面向組織）側 140509.doc -20- 201016253 308。該基部304之第〉面内（面向組織）側3〇8可具有一點 膠（未詳細顯示）以將第一附接基部構件3〇2附接至一击者的 表皮（或附接至患者的表皮上之-密封構件）。在代來 式之實施例中，機械裝置（例如，縫合線）亦可用以將第二 ' 附接基部構件3〇2牢固至患者的表皮。在第二、面向内側 . 则上之黏膠-開始可被覆蓋_可撕除之襯㈣料，在施 用至患者的表皮之前可移除該概背材料。該第一附接 籲構件302亦包括-被輕接（例如，附接或與該基部綱一體 成形）至該基部304之壁部31〇。壁部3ι〇具有一第一端邙 312及—第二端部314。該第—端部3U可形成有—第一; 動連接構件316，該第-可動連接構件係經形成為該壁部 31〇之-整體部分或附接至該壁部。該第二端部314可形成 广第二可動連接構件318 ’該第二可動連接構件係經形 成為該壁部310之一整體部分或附接至該壁部。—釣狀構 件32〇(如以下將進一步說明)可用以刺穿、抓持或固持一密 参㈣縮構件322。該鉤狀構件32〇可經形成為壁部3ι〇或基 部304之一整體部分或附接至該壁部或該基部。 現請參考® 3，複數個連接構件（諸如第—連接構件叫 可用以作為該模組式減壓、傷口閉合系統3〇〇之部件。每 一連接構件326具有-第二壁部328，該第二壁部具有一第 一端部330及第二端部332。該第二壁部似可經塑形以呈 有-梹形構形或者可為平直狀。該第一端部33〇可形成= 或餘接至該第-端部謂之—第三可動連接構件州。同 樣地’該第二端部332可形成有或被麵接至該第二端部332 140509.doc •21 - 201016253 之一第四可動連接構件336。該等可動連接構件334及33ό 經定大小且經構形而以一協調方式與該等可動連接構件 316及318協同作用，其允許在每一附接基部構件3〇2與每 一相鄰的耦接連接構件326之間相對移動，諸如樞轉移 動。在此一說明性實施例中，該等可動連接構件334及33 6 係被圖示為針狀構件，其等經定大小且經構形以滑入至第 一及第二可動連接構件316及318中，該等連接構件係插 口，其經定大小且經構形以接收可動連接構件334及336之 針狀形狀。當然，該等針狀構件及插口亦可配置成彼此相 _ 反或混合且相匹配。 雖然一 敉湮导官（諸如圖丨中之第二減壓輸送導管156)可 直接被施加通過該壁部31〇，然而可在第—附接基部構件 302之壁部310上使用一減壓界面342。例如，該第一附接 基部構件302可經修改以形成一如圖續示之減壓界面構件 340。除了已增添該減廢界面⑷外，該減麼界面構件… 參 係類似於第一附接基部構件3〇2。該減壓界面342可以係一 延伸穿過-壁部346之琿口 344。或者，一減壓界面可形成 有一被安置成穿過該連接構件326之埠口（例如， 344)。 平 先前所述之模組式組件，亦即，該第一附接基部構件 3〇2、該第—連接構件326及該減壓界面構件340係可經組 合以形成各種不同形狀且藉此可配合不同大小及形狀之傷 口。在圖5Α及㈣顯示—實例。該等經组合之構件 -表面傷口 3〇1上形成該模組式減屋、傷口閉合系統 140509.doc •22· 201016253 請特別參考圖5A，圖示之模組式減壓、傷口閉合系統3〇〇 係具有複數個附接基部構件：該第一附接基部構件3〇2、 一第二附接基部構件35〇及一第三附接基部構件352。圖中 亦顯示一第四附接基部構件，但經修改以形成具有該減壓 • 界面342之減壓界面構件340。一減壓導管354可流體式地 耗接至該減壓界面3 4 2。 複數個連接構件係用以連接該等複數個附接基部構件 • 302、35〇、352、340(界面）之每一者。因此，在此一說明 性實施例中，該第一附接基部構件3〇2係以該第一端部3 12 被耦接至該第一連接構件326，其該耦接係在該第一連接 構件326之第二端部332處。同樣地，該第二附接基部構件 350被耦接至一第二連接構件356。該第二連接構件亦 被耦接至第二附接基部構件352。該第三附接基部構件352 被耦接至一第三連接構件358，而該第三連接構件亦被耦 接至該減壓界面構件34〇。該減壓界面構件34〇被耦接至一 • 第四連接構件360。以此方式，該複數個附接基部構件及 複數個連接構件形成一界定一内部空間381之圓周壁部 3 80 ’且一密封收縮構件322係被安置於該内部空間中。該 密封收縮構件383可藉由鉤部（例如，位在該第一附接基部 構件302上之鉤部32〇)或者藉由黏膠、結合、熔接或其他 附接裝置而被固持靠近該附接基部構件。該密封收縮構件 322亦可附接至該圓周壁部38〇之全部或一部分。 應瞭解，該複數個附接基部構件與複數個連接構件之該 等父替構件係針對可以移動之連接部而提供。當該模組式 140509.doc •23· 201016253 減壓、傷口閉合系統300從圖5A之非收縮位置變成圖沾所 不之收縮位置時，此移動係有幫助的。亦應瞭解，雖然在 此5兒明中僅顯示四個連接構件及四個附接基部構件，然 而可以使用位意數量的這些組件以形成較大或較小的系 統例如，在圖6中之一模組式減壓傷口閉合系統4〇〇係顯 示一較大的系統構形。 在此一說明性實施例中之模組式減壓、傷口閉合系統 4〇〇係包括複數個附接基部構件，其具有七個附接基部構 件402且另一個則經修改以形成一減壓界面4〇4。該模組式 減壓、傷口閉合系統400亦包括複數個連接構件，在此一 說明性實施例中係包括八個連接構件4〇6。該複數個附接 基部構件402及複數個連接構件4〇6係可移動地耦接以形成 一界定一内部空間410之圓周壁部4〇8。—密封收縮構件 412係被放置在該内冑空間彻中且被耦接至少該複數個附 接基部構件402。該密封收縮構件412能以一類似於圖2之 鉤部320或其他附接裝置之方式利用該複數個附接基部構 件402上之鉤部來予以耦接。當減壓經由一減壓界面414被 供應在該減壓界面構件404上時，該減壓造成該密封收縮 構件412收縮且將複數個附接基部構件4〇2之每一者向内拉 攏且因此提供一閉合力。 雖然已在某些說明性、非限制性實施例之背景中揭示了 本發明及其優點，但應瞭解，仍可實施各種改變、替代、 變換及變更，而不背離由隨附申請專利範圍界定之本發明 之範疇。 140509.doc -24 - 201016253 【圖式簡單說明】 圖1係一減壓、傷口閉合及治療系統之一說明性實施例 之一概要橫截面視圖，其中一部分係以一方塊示意圖顯 示； 圖2係一附接基部構件之一說明性實施例的概要立體視 圖’ 3亥附接基部構件係用則乍& _減壓、傷口閉合系統之 一說明性實施例的部分；
圖3係一連接構件之一說明性實施例的概要立體視圖， 該連接構件係'用以作為—減壓ϋ合系統之-說明性 實施例的部分； 圖4係減壓界面構件之一說明性實施例的概要立體視 圖，該減壓界面構件係』以作為_減壓、#口閉合系統之 一說明性實施例的部分； 圖5Α及⑽一減壓、傷口閉合系統處在一非收縮位置 (圖5Α)與一收縮位置(圖5Β)之一說明性實施例的概要、平 面視圖；及 圖6係一減壓、傷σ閉人备&七 鸯閉σ糸統之一說明性實施例的概 要、立體視圖。 【主要元件符號說明】 100 減壓、傷口閉合 102 減壓治療子系統 104 傷口閉合子系統 106 組織部位 108 表皮 140509.doc -25- 201016253 110 腹腔 111 表面傷口 112 傷口邊緣 114 皮下組織 116 腹部内容物 118 歧管 120 歧管構件 122 非黏性封套 124 孔隙 126 孔隙 128 箭頭 132 密封構件 134 黏膠 136 附接裝置 138 第一減壓界面 140 減壓埠口 142 第一減壓輸送導管 144 箭頭 148 減壓子系統 150 第一減壓單元 151 第二減壓單元 152 導管 154 三通閥 156 第二減壓輸送導管 140509.doc -26- 201016253 ❿ ❿ 158 減壓導管 160 減壓反饋單元 162 罐子 164 中間部分 166 代表性裝置 170 箭頭 172 第一附接基部構件 174 第一基部 175 可動連接構件 176 第一壁部 177 第二減壓界面 178 第一側 180 第二、面向内側 182 第一黏膠 184 第二附接基部構件 185 基部 187 壁部 188 密封收縮構件 190 第一側 191 黏膠 192 第二、面内（面向組織）側 194 周緣邊緣 196 第一密封構件 198 第二密封構件 140509.doc •27· 201016253 200 周緣密封構件 201 開口 202 延伸部分 300 模組式減壓、傷口閉合系統 301 表面傷口 302 第一附接基部構件 304 基部 306 第一側 308 第二、面向内側 310 壁部 312 第一端部 314 第二端部 316 第一可動連接構件 318 第二可動連接構件 320 鉤部 322 密封收縮構件 326 第一連接構件 328 第二壁部 330 第一端部 332 第二端部 334 第三可動連接構件 336 第四可動連接構件 340 減壓界面構件 342 減壓界面 140509.doc -28- 201016253 344 埠口 346 壁部 350 第二附接基部構件 352 第三附接基部構件 • 354 減壓導管 356 第二連接構件 358 第三連接構件 Φ 360 第四連接構件 380 圓周壁部 381 内部空間 383 密封收縮構件 400 模組式減壓、傷口閉合系統 402 附接基部構件 404 減壓界面 406 連接構件 408 圓周壁部 410 内部空間 412 密封收縮構件 * 414 減壓界面 140509.doc •29-

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  1. 201016253 七、申請專利範園： 1. 一種用於在一串、去夕 你心者之-表面傷口上產生 式朗、傷口閉合系統，該系統包含·· 力之模組 密t收縮構件’ _封收縮構件 減壓作用時會收縮； J锞作以當處在 複數個附接基部構件 B一黎 每—附接基部構件具有一篡邱 邱壁部’該第—壁部具有-第-端部及-第二二 ° ’ 5亥第-壁部之該第—端部具有-第-可動連接構: f該第-壁部之該第二端部具有一第二可動 母一附接基部構件得用％ ^ ^ 1構件係用於可釋放地附接至-患者的表皮 之一。卩分且用於耦接至該密封收縮構件. 複數個連接構件，每—連接構 第二壁部具有一第一端部 第土部，该 丨及帛一端部’該第二壁部之 端部具有一第三可動連接構件且該第二壁部之該 一端部具有一第四可動連接構件，每用 於可移動地減至該複數個附接基部構件之一者；牛係用 -第-減壓界面，其係流體式地輕接至該密封收縮構 ，该第-減Μ界面係可操作以至 構件；且 m 。其令《數個附接基部才冓件及該複數個連接構件係可 :喿作以可移動地耦接來形成一界定—内部空間之圓周壁 部且其中該密封收縮構件係可操作以被安置且被耦捿在 該内部空間尹。 I如請求^之模組式減慶、傷口閉合系，统，其中該複數 M0509.doc 201016253 =連接者之該第-可動連接構件及該第 件之每=:;=構件且其中該複數個連接構 件係包一動連接構 數^附接基部構件之該等针狀構件相配接與該複 3.如凊求項1之模組式 個附接基部構件係藉由—第一= = 其中該複數 縮構件且該複數個連接構件係藉由二 至該密封收縮構件。 第-黏膠而被耦接 參 4.模組式減麼、傷，系統，其中 界面包含-形成在該圓周壁部上之蟑口。 二I:::之模組式減壓、傷口閉合系統，其中該複數 料。Η構件及該複數個連接構件係包含一可挽性材 妾之至模組式減壓、傷口閉合系統，其進一步包 _ 分的釣狀構件基部構件之至少一者之—部 收縮構件係可操作以牢固該密封 入二求項1之模組式減壓、傷口閉合系統，其進一步包 ::被耦接至該複數個附接基部構件之至少一者之—部 、句狀構件且其巾該鉤狀構件係可操作以牢固該密封 收縮構件之至少—部分；且其中： 1複數個附接基部構件之每一者之該第—可動連接構 該第二可動連接構件係包含-針狀構件； 140509.doc -2. 201016253 該複數個連接構件之每一者之該第三可動連接構件及 該第四可動連接構件係包含插口，該等插口係經定大小 且經構形以與該複數個附接基部構件之該等針狀構件相 配接；且 該複數個附接基部構件及該複數個連接構件係包含一 可撓性材料。 3 8. -種製造-用於在一患者之一表面傷口上產生_閉合力 之模組式減壓、傷口閉合系統之方法，該方法包含 之步驟： 形成-密封收縮構件’該密封收縮構件係可操作以當 受到減壓作用時會收縮； 田 形成複數個附接基部構件，每一附接基部構件具有一 基部及-第一壁部，該第一壁部具有—第一端部：一第 二端部，該第一壁部之該第一端部具有一第—可動連接 構件且該第-壁部之該第二端部具有—第二可動連接構 件，每一附接基部構件係用於可释放地附接至一患者的 表皮之一部分且用於耦接至該密封收縮構件； 形成複數個連接構件，每一連接構件具有一第二壁 部，該第二壁部具有一第一端部及—第二端部，該第二 壁部之該第一端部具有一第三可動連接構件且該第二壁 部之該第二端部具有—第四可動連接構件，每—連接構 件係用於可移動地麵接至該複數個附接基部構件之至少 兩個；且 其中該複數個附接基部構件及該複數個連接構件係可 140509.doc 201016253 操作以可移動_接來形成-界定-内部”之圓周壁 部。 v王 月长項8之模組式減壓、傷口閉合系統的製造方 形成複數個附接基部構件之該步驟係包 該等複數個附接基部構件之攻 件U楚^ 者具有經形成為針狀構 :亥第—可動連接構件及該第二可動連接構件；且其 馨 ::複數個連接構件之該步驟係包含形成該複數個連 件ST 一者具有經形成為插口之該第三可動連接構 ^ :第四可動連接構件，該等插口係㈣大小且經構 2 =該複數個附接基部構件之該等針狀構件相配接。 壓1 口閉合系統的製造方 收㈣Γ步包含麵接該複數個附接基部構件至該密封 收縮構件及耦接該複數個連接 該等步驟。 t以讀收縮構件之 u:請:ΓΓ模組式減壓、傷口閉合系統的製造方 ❿ 構件之至少一者之一部分的該步t複數個附接基部 12·如請求項8之一模組 法，其進一步包含以下之步驟·傷閉合系統的製造方 的麵=鉤狀構件至該複數個附接基部構件之至少—者 其中形成複數個附接基部構件之該 數個附接基部構件之每一者具：广形成該複 第一可動ϋ八百左形成為針狀構件之該 動連接構件及該第二可動連接構件；且 140509.doc -4- 201016253 vi双调迓祓構件之該步驟 個連接構件之每-者具有經形成為插口之：：成該複數 :妾構件及該第四可動連接構件，該等 ' ㈣ :構形以與該複數個附接基部構件之該等針狀:::: 13· -種用於在—患者之—表面“ 法’該方法包含以下之步驟·· 閉合力之方 提供一密封收縮構件； 提供複數個附接基部構件，每— 基部及-第-壁部，該第一壁部1有：；T具有一 二端部，該第—壁部端部及一第 構件且該第二端部具右唆 有第一可動連接 其^“第二可動連接構件，每-府接 U構件係用於可釋放地附接至接 分； 〜、者的表皮之一部 提^數個連接構件，每—連接構件具有_第二辟 壁部具有—第—端部及—第二端部，該第二 2邛之該第一端部具有_ —° 部之該第二端邻呈古可動連接構件且該第二壁 件係用…：第四可動連接構件，每-連接構 可移動地―地輕接至該複數個附接基部構件； 構件以形成_界=複1^附接基部構件及該複數個連接 界疋一内部空間之圓周壁部； 將該密封收縮構件安置在該内部空間中. 麵接該密封收縮構件至該圓周壁少 供應減壓至該密封收 "4刀，及 縮構件’藉此產生—力量來將該 140509.doc 201016253 等附接基部構件拉向該表面傷口之—内部以在 口上產生一閉合力。 劳 14·如請求項13之用於在-患者之-表面傷口上產生-閉合 力的方法，其中提供複數個附接基部構件之該步驟係包 :提：複數個附接基部構件，其中該複數個附接基部構 ::每-者的該第一可動連接構件及該第二 件係包含針狀構件，·且其中提供複數個 ： 驟係包含提供複數個連接構件，其中該複數個連接= 馨 之該第三可動連接構件及該第四可動連接構件 广 ’該等插口係經定大小且經構形以與該複數 個附接基部構件之該等針狀構件相配接。 請求们3之料在—患者之—表面傷口上產生_閉合 、法其中耦接s亥岔封收縮構件至該圓周壁部之至 部分的該步驟係包含純該複數個附接基部 該密封收縮構件。 至 謇 16.1^項13之用於在—患者之—表面傷口上產生—閉合 、法，其進一步包含在該圓周壁部之一部分上 整界面之步驟且其中供應減壓至該密封收縮 V驟係包含供應減壓至該減壓界面。 17.種用於提供-閉合力至一患者之一表 送減壓至一知诚* 且用於輸 系統包含織雜的減壓、傷1合及、冶療系統，該 一傷口閉合子系統，包含： 一密封收縮構件，該密封收縮構件係可操作以當處 140509.doc -6- 201016253 在減壓作用下會收縮， 複數個附接基部構件，主 再1千每—附接基部構件且右一其 部及一第-壁部，該第1 構件具有基 二端部’該第-壁部之嗲笛* L第 β第一端部具有— 接構件且該第一壁部之嗲 可動連 接槿株备 &之4第二端部具有一第二可動連 接構件，每一附接基部構 千係用於可釋放地附接至- 思者的表皮之一部分且用 、fe I 用於耦接至該密封收縮構件，
    複數個連接構件，每— 午 4直既立 母連接構件具有一第二壁部， 該第二壁部具有一第—端 鲕部及一第二端部，該第二壁 口 P之該第一端部具有—篦_ ^第二可動連接構件且該第二壁 技該第二端部具有-第四可動連接構件，每一連接 構件係用於可移動地麵接至該複數個附接基部構件， 閉口減壓界面，其係流體式地相接至該密封收縮 構件該第4壓界面係可操作以輸送減壓至該密封 收縮構件， -中《亥複數個附接基部構件及該複數個連接構件係 可操作以可移動地耦接來形成一界定一内部空間之圓 周壁部且其中該密封收縮構件係可操作以被安置且被 耦接在該内部空間中，及 一減Μ治療子系統，包含： 一歧管，其用於安置在靠近該組織部位處，該歧管 係可操作以分佈減壓且用以接收流體， 一密封構件，其用於放置在該患者的表皮上且可操 作以在該歧管上形成一氣動式密封，及 140509.doc 201016253 一治療減壓界面，其係流體式地耦接至該歧管，該 治療減壓界面係可操作以輸送一第二減壓至該歧管。 18. 19. 20. 21. 22. 如請求項17之用於提供一閉合力至一患者之一表面傷口 且用於輸送減壓至一組織部位之減壓、傷口閉合及治療 系統，其中該複數個附接基部構件之每一者之該第—可 動連接構件及該第二可動連接構件係包含針狀構件且其 中省複數個連接構件之每一者之該第三可動連接構件及 該第四可動連接構件係包含插口，該等插口係經定大小 且經構形以與該複數個附接基部構件之該等針狀構件 配接。 如請求項17之用於提供一閉合力至一患者之一表面傷口 且用於輸送減壓至一組織部位之減壓、傷口閉合及治療 系統，其中該複數個附接基部構件係藉由—黏膠而= 接至該密封收縮構件。 如請求項17之用於提供一閉合力至一患者之一表面傷口 且用於輸送減壓至一組織部位之減壓、傷口閉合及:: 系統，其中該複數個附接基部構件及該複數 ：： 係包含一可撓性材料。 如請求項17之用於提供-閉合力至—患者之—表面傷口 且用於輸送減壓至一組織部位之減壓、傷口閉合及治 系統’其進-步包含一被耦接至該複數個附接基部：： 之至少-者之-部分的鉤狀構件且其中該鉤狀構件係 操作以牢固該密封收縮構件之至少一部分。 ’、可 如請求項17之用於提供一閉合力至一串、 一表面傷口 140509.doc 201016253 且用於輸送減壓至-組織部位之減壓、傷口閉合及治療 系統，其進-步包含一被耦接至該複數個附接基部構件 u少n部分的釣狀構件且其中該鉤狀構件係可 操作以牢固該密封收縮構件之至少一部分；且其中. 該複數個附接基部構件之每一者之該第一可動連接構 件及該第：可動連接構件係包含針狀構件； 該複數個連接構件之每一者之該第三可動連接 • 該第四可動連接構件係包含插口，該等插口係經定大小 ::構:以與該複數個附接基部構件之該等針狀構件相 =複數個附接基部構件及該複數個連接構件係 可撓性材料。 3 140509.doc
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