TW200404541A - Pyridine derivatives - Google Patents

Pyridine derivatives Download PDF

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Publication number
TW200404541A
TW200404541A TW092125337A TW92125337A TW200404541A TW 200404541 A TW200404541 A TW 200404541A TW 092125337 A TW092125337 A TW 092125337A TW 92125337 A TW92125337 A TW 92125337A TW 200404541 A TW200404541 A TW 200404541A
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Taiwan
Prior art keywords
alkyl
methyl
group
phenyl
substituted
Prior art date
Application number
TW092125337A
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English (en)
Chinese (zh)
Inventor
Neil Pegg
Paul Beswick
Martin Swarbrick
John Skidmore
Sandeep Modi
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Glaxo Group Ltd
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Publication of TW200404541A publication Critical patent/TW200404541A/zh

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    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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TW092125337A 2002-09-16 2003-09-15 Pyridine derivatives TW200404541A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0221443.5A GB0221443D0 (en) 2002-09-16 2002-09-16 Pyridine derivates

Publications (1)

Publication Number Publication Date
TW200404541A true TW200404541A (en) 2004-04-01

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ID=9944138

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Application Number Title Priority Date Filing Date
TW092125337A TW200404541A (en) 2002-09-16 2003-09-15 Pyridine derivatives

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US (1) US7446117B2 (enExample)
EP (1) EP1546107B1 (enExample)
JP (1) JP4630063B2 (enExample)
KR (1) KR20050046782A (enExample)
CN (1) CN1681788A (enExample)
AR (1) AR041246A1 (enExample)
AT (1) ATE462694T1 (enExample)
AU (1) AU2003276063A1 (enExample)
BR (1) BR0313718A (enExample)
CA (1) CA2493497A1 (enExample)
DE (1) DE60331931D1 (enExample)
ES (1) ES2343316T3 (enExample)
GB (1) GB0221443D0 (enExample)
IL (1) IL166460A0 (enExample)
IS (1) IS7659A (enExample)
MA (1) MA27436A1 (enExample)
MX (1) MXPA05002886A (enExample)
NO (1) NO20050662L (enExample)
NZ (1) NZ538201A (enExample)
PL (1) PL376023A1 (enExample)
RU (1) RU2005103618A (enExample)
TW (1) TW200404541A (enExample)
WO (1) WO2004024691A1 (enExample)
ZA (1) ZA200501174B (enExample)

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WO2005007627A1 (ja) * 2003-07-18 2005-01-27 Nihon Nohyaku Co., Ltd. フェニルピリジン誘導体、その中間体及びこれを有効成分とする除草剤
EP2774925B1 (en) 2005-11-08 2016-12-28 Vertex Pharmaceuticals Incorporated Heterocyclic modulators of ATP-binding cassette transporters
WO2008141119A2 (en) 2007-05-09 2008-11-20 Vertex Pharmaceuticals Incorporated Modulators of cftr
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PL2231606T3 (pl) * 2007-12-07 2013-07-31 Vertex Pharma Sposoby wytwarzania kwasów cykloalkilokarboksyamidopirydynobenzoesowych
HUE031913T2 (en) 2007-12-07 2017-08-28 Vertex Pharma Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid
JP5523352B2 (ja) 2008-02-28 2014-06-18 バーテックス ファーマシューティカルズ インコーポレイテッド Ｃｆｔｒ修飾因子としてのへテロアリール誘導体
US8012976B2 (en) 2008-08-06 2011-09-06 Biomarin Pharmaceutical Inc. Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP)
WO2010046780A2 (en) * 2008-10-22 2010-04-29 Institut Pasteur Korea Anti viral compounds
US8541403B2 (en) 2010-02-03 2013-09-24 Biomarin Pharmaceutical Inc. Dihydropyridophthalazinone inhibitors of poly(ADP-ribose)polymerase (PARP) for use in treatment of diseases associated with a PTEN deficiency
DK2533640T3 (en) 2010-02-08 2017-01-23 Medivation Technologies Inc METHODS OF SYNTHESIS OF DIHYDROPYRIDOPHTHALAZINE DERIVATIVES
RS62767B1 (sr) 2010-04-07 2022-01-31 Vertex Pharma Farmaceutski sastavi 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5-il) ciklopropankarboksamido)-3-metilpiriodin-2-il)benzojeve kiseline i njihova primena
PL2630146T3 (pl) 2010-10-21 2020-11-02 Medivation Technologies Llc Krystaliczna sól tosylanowa (8S,9R)-5-fluoro-8-(4-fluorofenylo)-9-(1-metylo-1H-1,2,4-triazol-5-ilo)-8,9-dihydro-2H-pirydo[4,3,2-de]ftalazyno-3(7H)-onu
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EP1546107B1 (en) 2010-03-31
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