TR201902402T4 - İmmünojenik kompozisyonları stabilize eden ve bunların çökelmesini inhibe eden formülasyonlar. - Google Patents
İmmünojenik kompozisyonları stabilize eden ve bunların çökelmesini inhibe eden formülasyonlar. Download PDFInfo
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- TR201902402T4 TR201902402T4 TR2019/02402T TR201902402T TR201902402T4 TR 201902402 T4 TR201902402 T4 TR 201902402T4 TR 2019/02402 T TR2019/02402 T TR 2019/02402T TR 201902402 T TR201902402 T TR 201902402T TR 201902402 T4 TR201902402 T4 TR 201902402T4
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- Prior art keywords
- immunogenic compositions
- precipitation
- inhibit
- formulations
- stabilize
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- 239000000203 mixture Substances 0.000 title abstract 7
- 230000002163 immunogen Effects 0.000 title abstract 4
- 238000009472 formulation Methods 0.000 title abstract 3
- 238000001556 precipitation Methods 0.000 title abstract 3
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000011521 glass Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
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- A61K39/085—Staphylococcus
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- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
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- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
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- A—HUMAN NECESSITIES
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Inorganic Chemistry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Mevcut buluş, polisakarit-protein konjügatları ve protein immünojenleri gibi immünojenik kompozisyonların stabilitesini geliştirmeye yönelik bu konuda devam eden ihtiyaca hitap eder. Buluş geniş olarak immünojenik kompozisyonları stabilize eden ve bunların çökelmesini inhibe eden yeni formülasyonlar ile ilgilidir. Daha belirgin olarak aşağıda tarif edilen buluş, fermentörler, biyo-reaktörler, şişeler, cam kaplar, poşetler, şırıngalar, kauçuk stoperler, tüpler ve benzeri gibi kap vasıtaları içinde işlenen, geliştirilen, formüle edilen, üretilen ve/veya saklanan immünojenik kompozisyonları stabilize eden ve bunların partikülat oluşumunu (örn. agregasyonunu, çökelmesini) inhibe eden formülasyonlara yönelik bu konudaki ihtiyacı ele alır.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79526106P | 2006-04-26 | 2006-04-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
TR201902402T4 true TR201902402T4 (tr) | 2019-03-21 |
Family
ID=38441477
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
TR2019/02402T TR201902402T4 (tr) | 2006-04-26 | 2007-04-19 | İmmünojenik kompozisyonları stabilize eden ve bunların çökelmesini inhibe eden formülasyonlar. |
Country Status (30)
Country | Link |
---|---|
US (3) | US7935787B2 (tr) |
EP (5) | EP2679245B1 (tr) |
JP (7) | JP5612305B2 (tr) |
KR (9) | KR20140132779A (tr) |
CN (4) | CN103768615B (tr) |
AR (2) | AR060665A1 (tr) |
AU (1) | AU2007243019B2 (tr) |
BR (2) | BR122020000285B1 (tr) |
CA (3) | CA2803111C (tr) |
CL (1) | CL2007001185A1 (tr) |
CR (1) | CR10405A (tr) |
CY (2) | CY1116966T1 (tr) |
DK (4) | DK2010219T3 (tr) |
EA (2) | EA023470B1 (tr) |
ES (4) | ES2712956T3 (tr) |
FR (1) | FR22C1027I1 (tr) |
HK (3) | HK1196546A1 (tr) |
HR (3) | HRP20151203T1 (tr) |
HU (5) | HUE042923T2 (tr) |
IL (3) | IL194753A (tr) |
LT (2) | LT2676679T (tr) |
MX (3) | MX2008013572A (tr) |
PL (4) | PL2679244T3 (tr) |
PT (4) | PT2679245T (tr) |
RU (1) | RU2482878C2 (tr) |
SI (4) | SI2679244T1 (tr) |
TR (1) | TR201902402T4 (tr) |
TW (1) | TW200806315A (tr) |
WO (1) | WO2007127665A2 (tr) |
ZA (1) | ZA200809167B (tr) |
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