TR200103666T2 - Zayìflatìlmìç pestivirsler - Google Patents

Zayìflatìlmìç pestivirsler

Info

Publication number
TR200103666T2
TR200103666T2 TR2001/03666T TR200103666T TR200103666T2 TR 200103666 T2 TR200103666 T2 TR 200103666T2 TR 2001/03666 T TR2001/03666 T TR 2001/03666T TR 200103666 T TR200103666 T TR 200103666T TR 200103666 T2 TR200103666 T2 TR 200103666T2
Authority
TR
Turkey
Prior art keywords
pestivir
weakened
pestiviruses
weak
stopped
Prior art date
Application number
TR2001/03666T
Other languages
English (en)
Inventor
Meyers Gregor
Original Assignee
Boehringer Ingelheim Kg.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg. filed Critical Boehringer Ingelheim Kg.
Publication of TR200103666T2 publication Critical patent/TR200103666T2/tr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13—Tumour cells, irrespective of tissue of origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24361—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Buluç, karakteristik özelliGi,ERNS glikoproteini içinde yer alan enzim etkinliklerinin durdurulmuç olmas olan, zay flat lm ç pestivirüslere, bunlar haz rlama yöntemlerine ve yine bunlar n kullan lmalar na ve saptanmalar na iliçkindir.
TR2001/03666T 1998-06-05 1999-05-26 Zayìflatìlmìç pestivirsler TR200103666T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP98110356A EP0965639A1 (en) 1998-06-05 1998-06-05 Attenuated pestiviruses

Publications (1)

Publication Number Publication Date
TR200103666T2 true TR200103666T2 (tr) 2002-03-21

Family

ID=8232074

Family Applications (3)

Application Number Title Priority Date Filing Date
TR2001/03666T TR200103666T2 (tr) 1998-06-05 1999-05-26 Zayìflatìlmìç pestivirsler
TR2001/03664T TR200103664T2 (tr) 1998-06-05 1999-05-26 Zayıflatılımış pestivirüsler
TR2000/03622T TR200003622T2 (tr) 1998-06-05 1999-05-26 Zayıflatılımış Pestivirüsler.

Family Applications After (2)

Application Number Title Priority Date Filing Date
TR2001/03664T TR200103664T2 (tr) 1998-06-05 1999-05-26 Zayıflatılımış pestivirüsler
TR2000/03622T TR200003622T2 (tr) 1998-06-05 1999-05-26 Zayıflatılımış Pestivirüsler.

Country Status (23)

Country Link
EP (5) EP0965639A1 (tr)
JP (3) JP4632540B2 (tr)
KR (1) KR100637940B1 (tr)
CN (2) CN100374563C (tr)
AR (3) AR020084A1 (tr)
AT (3) ATE311193T1 (tr)
AU (1) AU769823C (tr)
BR (2) BR9911619B1 (tr)
CA (1) CA2330241C (tr)
CO (1) CO5050392A1 (tr)
CZ (3) CZ301494B6 (tr)
DE (3) DE69922953T2 (tr)
DK (3) DK1203812T3 (tr)
ES (3) ES2253457T3 (tr)
HU (3) HU228469B1 (tr)
NZ (1) NZ509228A (tr)
PE (1) PE20000552A1 (tr)
PL (2) PL202509B1 (tr)
PT (2) PT1203813E (tr)
SI (3) SI1084251T1 (tr)
SK (3) SK287014B6 (tr)
TR (3) TR200103666T2 (tr)
WO (1) WO1999064604A2 (tr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179473B2 (en) 1998-06-05 2007-02-20 Boehringer Ingelheim Vetmedica Gmbh Attenuated pestiviruses
EP1104676A1 (en) 1999-11-30 2001-06-06 Boehringer Ingelheim Vetmedica Gmbh Safe attenuated bovine viral diarrhea viruses for use in pregnant cows
DE60118456T2 (de) * 2000-04-21 2006-08-24 Akzo Nobel N.V. Pestvirus Mutanten und diese enthaltende Impfstoffe
US7135561B2 (en) 2001-09-06 2006-11-14 Boehringer Ingelheim Vetmedica Gmbh Infectious bovine viral diarrhea virus clone
UY29915A1 (es) * 2005-11-15 2007-06-29 Boehringer Ingelheim Vetmed Vacuna combinada que comprende un virus atenuado de la diarrea viral bovina
AR069087A1 (es) 2007-10-29 2009-12-30 Boehringer Ingelheim Vetmed Cepa bacteriana de m. bovis atenuada avirulenta obtenida por pases, vacuna de micoplasma boris y metodos de uso de la misma
UY31930A (es) 2008-06-25 2010-01-29 Boheringer Ingelheim Pharma Kg Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante
CN102202685A (zh) 2008-10-31 2011-09-28 贝林格尔.英格海姆维特梅迪卡有限公司 包含来自牛枝原体的抗原的多种抗原在多价疫苗组合物中的用途
US8846054B2 (en) 2009-01-09 2014-09-30 Boehringer Ingelheim Vetmedica, Inc. Method of treating pregnant cows and/or heifers
UY32570A (es) 2009-04-24 2010-11-30 Boehringer Ingelheim Vetmed Vacuna viva modificada de mycoplasma bovis mejorada
CN101915837B (zh) * 2010-07-28 2013-07-03 中国兽医药品监察所 一种猪瘟兔化弱毒活疫苗效力检验方法
WO2012038454A1 (en) 2010-09-21 2012-03-29 Intervet International B.V. Bvdv vaccine
CN103882051B (zh) * 2014-03-20 2016-04-06 北京市农林科学院 一种检测猪瘟病毒抗体的elisa方法及检测试剂盒
US20230181710A1 (en) * 2019-04-18 2023-06-15 Boehringer Ingelheim Vetmedica (China) Co. Ltd. Recombinant classical swine fever virus

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE164885T1 (de) * 1986-01-27 1998-04-15 Syntro Corp Abgeschwächte herpesviren, herpesviren, die eine für aminosäuresequenzen kodierende fremd-dns enthalten, sowie impfstoffe, die diese enthalten

Also Published As

Publication number Publication date
SK287625B6 (sk) 2011-04-05
DE69929544D1 (de) 2006-04-13
SI1203812T1 (sl) 2006-04-30
AU769823C (en) 2004-11-25
SI1084251T1 (tr) 2005-08-31
SI1203813T1 (sl) 2006-06-30
AU769823B2 (en) 2004-02-05
EP1203813B1 (en) 2006-01-25
CZ20004533A3 (cs) 2001-07-11
WO1999064604A3 (en) 2000-01-27
EP0965639A1 (en) 1999-12-22
DE69922953T2 (de) 2005-05-19
HU228469B1 (en) 2013-03-28
DE69928700T2 (de) 2006-06-22
BRPI9917787B1 (pt) 2016-09-06
HUP0102707A3 (en) 2008-04-28
EP1614423A3 (en) 2008-01-30
ES2235488T3 (es) 2005-07-01
WO1999064604A2 (en) 1999-12-16
AU4369299A (en) 1999-12-30
ES2257476T3 (es) 2006-08-01
BR9911619A (pt) 2001-10-02
SK18232000A3 (sk) 2001-05-10
JP2010259445A (ja) 2010-11-18
AR071880A2 (es) 2010-07-21
ATE286131T1 (de) 2005-01-15
CZ301569B6 (cs) 2010-04-21
AR020084A1 (es) 2002-04-10
AR071881A2 (es) 2010-07-21
CO5050392A1 (es) 2001-06-27
EP1203812B1 (en) 2005-11-30
DE69929544T2 (de) 2006-07-20
CN1304452A (zh) 2001-07-18
CN101085346A (zh) 2007-12-12
ATE311193T1 (de) 2005-12-15
JP5247770B2 (ja) 2013-07-24
EP1203813A3 (en) 2004-02-04
DK1203813T3 (da) 2006-05-22
CZ301570B6 (cs) 2010-04-21
DE69928700D1 (de) 2006-01-05
DE69922953D1 (de) 2005-02-03
DK1084251T3 (da) 2005-04-11
ES2253457T3 (es) 2006-06-01
HU228471B1 (en) 2013-03-28
EP1614423A2 (en) 2006-01-11
CZ301494B6 (cs) 2010-03-24
TR200003622T2 (tr) 2001-06-21
EP1203813A2 (en) 2002-05-08
EP1084251A2 (en) 2001-03-21
EP1203812A3 (en) 2004-02-04
JP2013099357A (ja) 2013-05-23
HUP0102707A2 (hu) 2001-11-28
KR20010071406A (ko) 2001-07-28
KR100637940B1 (ko) 2006-10-23
EP1203812A2 (en) 2002-05-08
PL348019A1 (en) 2002-05-06
HU228468B1 (en) 2013-03-28
EP1084251B1 (en) 2004-12-29
SK287014B6 (sk) 2009-09-07
PL202509B1 (pl) 2009-06-30
SK287626B6 (sk) 2011-04-05
CA2330241C (en) 2010-09-21
PT1084251E (pt) 2005-03-31
PL202161B1 (pl) 2009-06-30
PE20000552A1 (es) 2000-07-14
NZ509228A (en) 2003-12-19
JP5755265B2 (ja) 2015-07-29
PT1203813E (pt) 2006-06-30
CA2330241A1 (en) 1999-12-16
ATE316380T1 (de) 2006-02-15
JP2002517250A (ja) 2002-06-18
TR200103664T2 (tr) 2002-06-21
DK1203812T3 (da) 2006-04-10
JP4632540B2 (ja) 2011-02-16
CN100374563C (zh) 2008-03-12
BR9911619B1 (pt) 2013-11-12

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