PE20000552A1 - Pestivirus atenuados - Google Patents
Pestivirus atenuadosInfo
- Publication number
- PE20000552A1 PE20000552A1 PE1999000472A PE00047299A PE20000552A1 PE 20000552 A1 PE20000552 A1 PE 20000552A1 PE 1999000472 A PE1999000472 A PE 1999000472A PE 00047299 A PE00047299 A PE 00047299A PE 20000552 A1 PE20000552 A1 PE 20000552A1
- Authority
- PE
- Peru
- Prior art keywords
- pestivirus
- virus
- amino acids
- vfpc
- rns
- Prior art date
Links
- 230000002238 attenuated effect Effects 0.000 title 1
- 238000000034 method Methods 0.000 abstract 6
- 241000710778 Pestivirus Species 0.000 abstract 5
- 150000001413 amino acids Chemical class 0.000 abstract 5
- 241000700605 Viruses Species 0.000 abstract 4
- 101000807236 Human cytomegalovirus (strain AD169) Membrane glycoprotein US3 Proteins 0.000 abstract 3
- 102000006382 Ribonucleases Human genes 0.000 abstract 3
- 108010083644 Ribonucleases Proteins 0.000 abstract 3
- 241000283690 Bos taurus Species 0.000 abstract 2
- 206010012735 Diarrhoea Diseases 0.000 abstract 2
- 230000037430 deletion Effects 0.000 abstract 2
- 238000012217 deletion Methods 0.000 abstract 2
- 230000035772 mutation Effects 0.000 abstract 2
- 229960005486 vaccine Drugs 0.000 abstract 2
- 208000001726 Classical Swine Fever Diseases 0.000 abstract 1
- 241000710777 Classical swine fever virus Species 0.000 abstract 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 1
- 239000004472 Lysine Substances 0.000 abstract 1
- 229940031567 attenuated vaccine Drugs 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 abstract 1
- 230000000415 inactivating effect Effects 0.000 abstract 1
- 230000002779 inactivation Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/22—Ribonucleases RNAses, DNAses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
- C12N2770/24361—Methods of inactivation or attenuation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE REFIERE A UNA VACUNA VIVA QUE CONTIENE UN PESTIVIRUS ATENUADO O MARCADO DE FORMA DETECTABLE MEDIANTE LA INACTIVACION DE LA ACTIVIDAD DE LA RIBONUCLEASA (RNASA) QUE SE ENCUENTRA EN LA GLICOPROTEINA E(RNS). LA INACTIVACION DE LA RNASA ES POR MUTACIONES O DELECIONES EN LOS AMINOACIDOS DE LAS POSICIONES 295 A 307 Y/O EN LOS AMINOACIDOS DE LAS POSICIONES 338 A 357 DE LA CEPA ALFORT DEL VIRUS DE LA FIEBRE PORCINA CLASICA (VFPC) DE 495 AMINOACIDOS, DE PREFERENCIA POR DELECION DE HISTIDINA EN LA POSICION 346 DEL VFPC O DEL VIRUS DE LA DIARREA VIRAL BOVINA (VDVB) DE LA GLICOPROTEINA E(RNS); LA MUTACION O DELECION DE AL MENOS UN AMINOACIDO CON LA CONDICION DE QUE LOS AMINOACIDOS EN LAS POSICIONES 297 Y 346 DE LA CEPA ALFORT DE VFPC NO SEAN LISINA. TAMBIEN SE REFIERE A UN ACIDO NUCLEICO QUE CODIFICA LA GLICOPROTEINA E(RNS), UN METODO PARA ATENUAR PESTIVIRUS, PROCEDIMIENTO PARA PRODUCIR UNA VACUNA ATENUADA, METODO PARA MARCAR DE FORMA DETECTABLE EL PESTIVIRUS, PROCEDIMIENTO PARA LA PREPARACION DE PESTIVIRUS ESPECIFICAMENTE MARCADOS O ATENUADOS. LA VACUNA PUEDE SER UTIL PARA LA PROFILAXIS Y EL TRATAMIENTO DE INFECCIONES POR VIRUS DE LA DIARREA VIRAL BOVINA, VIRUS DE LA FIEBRE PORCINA CLASICA, VIRUS DE LA ENFERMEDAD DE BORDER
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP98110356A EP0965639A1 (en) | 1998-06-05 | 1998-06-05 | Attenuated pestiviruses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20000552A1 true PE20000552A1 (es) | 2000-07-14 |
Family
ID=8232074
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1999000472A PE20000552A1 (es) | 1998-06-05 | 1999-06-03 | Pestivirus atenuados |
Country Status (23)
| Country | Link |
|---|---|
| EP (5) | EP0965639A1 (es) |
| JP (3) | JP4632540B2 (es) |
| KR (1) | KR100637940B1 (es) |
| CN (2) | CN101085346A (es) |
| AR (3) | AR020084A1 (es) |
| AT (3) | ATE311193T1 (es) |
| AU (1) | AU769823C (es) |
| BR (2) | BRPI9917787B1 (es) |
| CA (1) | CA2330241C (es) |
| CO (1) | CO5050392A1 (es) |
| CZ (3) | CZ301494B6 (es) |
| DE (3) | DE69928700T2 (es) |
| DK (3) | DK1084251T3 (es) |
| ES (3) | ES2253457T3 (es) |
| HU (3) | HU228469B1 (es) |
| NZ (1) | NZ509228A (es) |
| PE (1) | PE20000552A1 (es) |
| PL (2) | PL202161B1 (es) |
| PT (2) | PT1084251E (es) |
| SI (3) | SI1084251T1 (es) |
| SK (3) | SK287014B6 (es) |
| TR (3) | TR200103666T2 (es) |
| WO (1) | WO1999064604A2 (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7179473B2 (en) | 1998-06-05 | 2007-02-20 | Boehringer Ingelheim Vetmedica Gmbh | Attenuated pestiviruses |
| EP1104676A1 (en) | 1999-11-30 | 2001-06-06 | Boehringer Ingelheim Vetmedica Gmbh | Safe attenuated bovine viral diarrhea viruses for use in pregnant cows |
| PT1149901E (pt) | 2000-04-21 | 2006-08-31 | Akzo Nobel Nv | Mutantes de pestivirus e vacinas contendo os mesmos |
| US7135561B2 (en) | 2001-09-06 | 2006-11-14 | Boehringer Ingelheim Vetmedica Gmbh | Infectious bovine viral diarrhea virus clone |
| UY29915A1 (es) * | 2005-11-15 | 2007-06-29 | Boehringer Ingelheim Vetmed | Vacuna combinada que comprende un virus atenuado de la diarrea viral bovina |
| UY31437A1 (es) | 2007-10-29 | 2009-05-29 | Vacuna de mycoplasma bovis y métodos de uso de la misma | |
| UY31930A (es) | 2008-06-25 | 2010-01-29 | Boheringer Ingelheim Pharma Kg | Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante |
| US8815255B2 (en) | 2008-10-31 | 2014-08-26 | Boehringer Ingelheim Vetmedica, Inc. | Use of Mycoplasma bovis antigen |
| US8846054B2 (en) | 2009-01-09 | 2014-09-30 | Boehringer Ingelheim Vetmedica, Inc. | Method of treating pregnant cows and/or heifers |
| UY32570A (es) | 2009-04-24 | 2010-11-30 | Boehringer Ingelheim Vetmed | Vacuna viva modificada de mycoplasma bovis mejorada |
| CN101915837B (zh) * | 2010-07-28 | 2013-07-03 | 中国兽医药品监察所 | 一种猪瘟兔化弱毒活疫苗效力检验方法 |
| EP2618841B1 (en) | 2010-09-21 | 2016-10-19 | Intervet International B.V. | Bvdv vaccine |
| CN103882051B (zh) * | 2014-03-20 | 2016-04-06 | 北京市农林科学院 | 一种检测猪瘟病毒抗体的elisa方法及检测试剂盒 |
| EP3956439A4 (en) * | 2019-04-18 | 2023-05-03 | Boehringer Ingelheim Vetmedica (China) Co., Ltd. | RECOMBINANT CLASSICAL SWINE FEVER VIRUS |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE342996T1 (de) * | 1986-01-27 | 2006-11-15 | Schering Plough Ltd | Attenuierte herpesviren, herpesviren die eine aminosäuresequenz kodierende fremde dna enthalten,und diese enthaltende impfstoffe |
-
1998
- 1998-06-05 EP EP98110356A patent/EP0965639A1/en not_active Withdrawn
-
1999
- 1999-05-26 BR BRPI9917787A patent/BRPI9917787B1/pt active IP Right Grant
- 1999-05-26 AT AT02003407T patent/ATE311193T1/de active
- 1999-05-26 TR TR2001/03666T patent/TR200103666T2/xx unknown
- 1999-05-26 ES ES02003407T patent/ES2253457T3/es not_active Expired - Lifetime
- 1999-05-26 PT PT99926430T patent/PT1084251E/pt unknown
- 1999-05-26 DK DK99926430T patent/DK1084251T3/da active
- 1999-05-26 DE DE69928700T patent/DE69928700T2/de not_active Expired - Lifetime
- 1999-05-26 AT AT99926430T patent/ATE286131T1/de active
- 1999-05-26 HU HU1200536A patent/HU228469B1/hu unknown
- 1999-05-26 SI SI9930746T patent/SI1084251T1/xx unknown
- 1999-05-26 EP EP99926430A patent/EP1084251B1/en not_active Expired - Lifetime
- 1999-05-26 ES ES02003408T patent/ES2257476T3/es not_active Expired - Lifetime
- 1999-05-26 WO PCT/EP1999/003642 patent/WO1999064604A2/en active Application Filing
- 1999-05-26 SK SK1823-2000A patent/SK287014B6/sk not_active IP Right Cessation
- 1999-05-26 DE DE69922953T patent/DE69922953T2/de not_active Expired - Lifetime
- 1999-05-26 BR BRPI9911619-7B1A patent/BR9911619B1/pt active IP Right Grant
- 1999-05-26 EP EP02003408A patent/EP1203813B1/en not_active Expired - Lifetime
- 1999-05-26 PT PT02003408T patent/PT1203813E/pt unknown
- 1999-05-26 AT AT02003408T patent/ATE316380T1/de active
- 1999-05-26 DK DK02003408T patent/DK1203813T3/da active
- 1999-05-26 JP JP2000553594A patent/JP4632540B2/ja not_active Expired - Lifetime
- 1999-05-26 DE DE69929544T patent/DE69929544T2/de not_active Expired - Lifetime
- 1999-05-26 DK DK02003407T patent/DK1203812T3/da active
- 1999-05-26 TR TR2000/03622T patent/TR200003622T2/xx unknown
- 1999-05-26 CZ CZ20004533A patent/CZ301494B6/cs not_active IP Right Cessation
- 1999-05-26 CN CNA2007101042355A patent/CN101085346A/zh active Pending
- 1999-05-26 SI SI9930882T patent/SI1203813T1/sl unknown
- 1999-05-26 HU HU1200537A patent/HU228471B1/hu unknown
- 1999-05-26 CZ CZ20090293A patent/CZ301570B6/cs not_active IP Right Cessation
- 1999-05-26 TR TR2001/03664T patent/TR200103664T2/xx unknown
- 1999-05-26 AU AU43692/99A patent/AU769823C/en not_active Expired
- 1999-05-26 CZ CZ20090294A patent/CZ301569B6/cs not_active IP Right Cessation
- 1999-05-26 SK SK50019-2009A patent/SK287626B6/sk not_active IP Right Cessation
- 1999-05-26 CA CA2330241A patent/CA2330241C/en not_active Expired - Lifetime
- 1999-05-26 PL PL384046A patent/PL202161B1/pl unknown
- 1999-05-26 CN CNB998070521A patent/CN100374563C/zh not_active Expired - Lifetime
- 1999-05-26 ES ES99926430T patent/ES2235488T3/es not_active Expired - Lifetime
- 1999-05-26 SI SI9930860T patent/SI1203812T1/sl unknown
- 1999-05-26 KR KR1020007013757A patent/KR100637940B1/ko not_active IP Right Cessation
- 1999-05-26 HU HU0102707A patent/HU228468B1/hu unknown
- 1999-05-26 PL PL348019A patent/PL202509B1/pl unknown
- 1999-05-26 SK SK50018-2009A patent/SK287625B6/sk not_active IP Right Cessation
- 1999-05-26 EP EP02003407A patent/EP1203812B1/en not_active Expired - Lifetime
- 1999-05-26 NZ NZ509228A patent/NZ509228A/en not_active IP Right Cessation
- 1999-05-26 EP EP05017098A patent/EP1614423A3/en not_active Withdrawn
- 1999-06-01 CO CO99034189A patent/CO5050392A1/es unknown
- 1999-06-03 PE PE1999000472A patent/PE20000552A1/es not_active Application Discontinuation
- 1999-06-04 AR ARP990102650A patent/AR020084A1/es active Pending
-
2009
- 2009-05-22 AR ARP090101843A patent/AR071881A2/es active Pending
- 2009-05-22 AR ARP090101842A patent/AR071880A2/es not_active Suspension/Interruption
-
2010
- 2010-07-26 JP JP2010167518A patent/JP5247770B2/ja not_active Expired - Lifetime
-
2013
- 2013-02-04 JP JP2013019815A patent/JP5755265B2/ja not_active Expired - Lifetime
Also Published As
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