ATE286131T1 - Attenuierte pestiviren - Google Patents

Attenuierte pestiviren

Info

Publication number
ATE286131T1
ATE286131T1 AT99926430T AT99926430T ATE286131T1 AT E286131 T1 ATE286131 T1 AT E286131T1 AT 99926430 T AT99926430 T AT 99926430T AT 99926430 T AT99926430 T AT 99926430T AT E286131 T1 ATE286131 T1 AT E286131T1
Authority
AT
Austria
Prior art keywords
pestiviruses
attenuate
attenuate pestiviruses
Prior art date
Application number
AT99926430T
Other languages
English (en)
Inventor
Gregor Meyers
Original Assignee
Boehringer Ingelheim Vetmed
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmed filed Critical Boehringer Ingelheim Vetmed
Application granted granted Critical
Publication of ATE286131T1 publication Critical patent/ATE286131T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13—Tumour cells, irrespective of tissue of origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24361—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT99926430T 1998-06-05 1999-05-26 Attenuierte pestiviren ATE286131T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98110356A EP0965639A1 (de) 1998-06-05 1998-06-05 Attenuierte Pestiviren
PCT/EP1999/003642 WO1999064604A2 (en) 1998-06-05 1999-05-26 Attenuated pestiviruses

Publications (1)

Publication Number Publication Date
ATE286131T1 true ATE286131T1 (de) 2005-01-15

Family

ID=8232074

Family Applications (3)

Application Number Title Priority Date Filing Date
AT99926430T ATE286131T1 (de) 1998-06-05 1999-05-26 Attenuierte pestiviren
AT02003407T ATE311193T1 (de) 1998-06-05 1999-05-26 Attenuierte pestiviren
AT02003408T ATE316380T1 (de) 1998-06-05 1999-05-26 Attenuierte pestiviren

Family Applications After (2)

Application Number Title Priority Date Filing Date
AT02003407T ATE311193T1 (de) 1998-06-05 1999-05-26 Attenuierte pestiviren
AT02003408T ATE316380T1 (de) 1998-06-05 1999-05-26 Attenuierte pestiviren

Country Status (23)

Country Link
EP (5) EP0965639A1 (de)
JP (3) JP4632540B2 (de)
KR (1) KR100637940B1 (de)
CN (2) CN101085346A (de)
AR (3) AR020084A1 (de)
AT (3) ATE286131T1 (de)
AU (1) AU769823C (de)
BR (2) BR9911619B1 (de)
CA (1) CA2330241C (de)
CO (1) CO5050392A1 (de)
CZ (3) CZ301569B6 (de)
DE (3) DE69928700T2 (de)
DK (3) DK1084251T3 (de)
ES (3) ES2235488T3 (de)
HU (3) HU228468B1 (de)
NZ (1) NZ509228A (de)
PE (1) PE20000552A1 (de)
PL (2) PL202509B1 (de)
PT (2) PT1084251E (de)
SI (3) SI1203813T1 (de)
SK (3) SK287014B6 (de)
TR (3) TR200103666T2 (de)
WO (1) WO1999064604A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179473B2 (en) 1998-06-05 2007-02-20 Boehringer Ingelheim Vetmedica Gmbh Attenuated pestiviruses
EP1104676A1 (de) * 1999-11-30 2001-06-06 Boehringer Ingelheim Vetmedica Gmbh Sichere abgeschwächte Rinderdiarrhöeviren zur Verwendung in trächtigen Kühen
DE60118456T2 (de) * 2000-04-21 2006-08-24 Akzo Nobel N.V. Pestvirus Mutanten und diese enthaltende Impfstoffe
US7135561B2 (en) 2001-09-06 2006-11-14 Boehringer Ingelheim Vetmedica Gmbh Infectious bovine viral diarrhea virus clone
UY29915A1 (es) 2005-11-15 2007-06-29 Boehringer Ingelheim Vetmed Vacuna combinada que comprende un virus atenuado de la diarrea viral bovina
CL2008003202A1 (es) 2007-10-29 2009-11-27 Boehringer Ingelheim Vetmedica Inc Composicion inmunogenica que comprende bacterias vivas de mycoplasma bovis atenuada avirulenta.
UY31930A (es) 2008-06-25 2010-01-29 Boheringer Ingelheim Pharma Kg Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante
NZ591950A (en) 2008-10-31 2012-12-21 Boehringer Ingelheim Vetmed Use of various antigens including antigens from mycoplasma bovis in multivalent vaccine composition
US8846054B2 (en) 2009-01-09 2014-09-30 Boehringer Ingelheim Vetmedica, Inc. Method of treating pregnant cows and/or heifers
UY32570A (es) 2009-04-24 2010-11-30 Boehringer Ingelheim Vetmed Vacuna viva modificada de mycoplasma bovis mejorada
CN101915837B (zh) * 2010-07-28 2013-07-03 中国兽医药品监察所 一种猪瘟兔化弱毒活疫苗效力检验方法
WO2012038454A1 (en) 2010-09-21 2012-03-29 Intervet International B.V. Bvdv vaccine
CN103882051B (zh) * 2014-03-20 2016-04-06 北京市农林科学院 一种检测猪瘟病毒抗体的elisa方法及检测试剂盒
KR20220009960A (ko) * 2019-04-18 2022-01-25 베링거 잉겔하임 베트메디카 (차이나) 코포레이션 리미티드 재조합 고전적 돼지 열병 바이러스

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE342996T1 (de) * 1986-01-27 2006-11-15 Schering Plough Ltd Attenuierte herpesviren, herpesviren die eine aminosäuresequenz kodierende fremde dna enthalten,und diese enthaltende impfstoffe

Also Published As

Publication number Publication date
CN1304452A (zh) 2001-07-18
HUP0102707A2 (hu) 2001-11-28
SK287014B6 (sk) 2009-09-07
EP1203812A2 (de) 2002-05-08
ES2257476T3 (es) 2006-08-01
JP5755265B2 (ja) 2015-07-29
AU769823B2 (en) 2004-02-05
HUP0102707A3 (en) 2008-04-28
EP0965639A1 (de) 1999-12-22
ES2235488T3 (es) 2005-07-01
DE69928700D1 (de) 2006-01-05
SK287626B6 (sk) 2011-04-05
AU4369299A (en) 1999-12-30
WO1999064604A2 (en) 1999-12-16
CA2330241C (en) 2010-09-21
EP1084251B1 (de) 2004-12-29
ATE316380T1 (de) 2006-02-15
CZ20004533A3 (cs) 2001-07-11
DE69922953T2 (de) 2005-05-19
DK1203813T3 (da) 2006-05-22
CA2330241A1 (en) 1999-12-16
SI1203812T1 (sl) 2006-04-30
AR020084A1 (es) 2002-04-10
JP5247770B2 (ja) 2013-07-24
EP1203813A3 (de) 2004-02-04
ES2253457T3 (es) 2006-06-01
DE69928700T2 (de) 2006-06-22
KR100637940B1 (ko) 2006-10-23
EP1084251A2 (de) 2001-03-21
WO1999064604A3 (en) 2000-01-27
EP1203813B1 (de) 2006-01-25
EP1614423A3 (de) 2008-01-30
AR071881A2 (es) 2010-07-21
DE69922953D1 (de) 2005-02-03
DE69929544T2 (de) 2006-07-20
EP1203812A3 (de) 2004-02-04
AR071880A2 (es) 2010-07-21
BRPI9917787B1 (pt) 2016-09-06
TR200103664T2 (tr) 2002-06-21
PT1203813E (pt) 2006-06-30
SI1084251T1 (de) 2005-08-31
EP1614423A2 (de) 2006-01-11
NZ509228A (en) 2003-12-19
SK287625B6 (sk) 2011-04-05
JP2013099357A (ja) 2013-05-23
CN101085346A (zh) 2007-12-12
CO5050392A1 (es) 2001-06-27
DE69929544D1 (de) 2006-04-13
JP2010259445A (ja) 2010-11-18
HU228469B1 (en) 2013-03-28
BR9911619A (pt) 2001-10-02
EP1203812B1 (de) 2005-11-30
SK18232000A3 (sk) 2001-05-10
DK1203812T3 (da) 2006-04-10
CZ301494B6 (cs) 2010-03-24
HU228471B1 (en) 2013-03-28
TR200103666T2 (tr) 2002-03-21
AU769823C (en) 2004-11-25
DK1084251T3 (da) 2005-04-11
EP1203813A2 (de) 2002-05-08
TR200003622T2 (tr) 2001-06-21
KR20010071406A (ko) 2001-07-28
JP4632540B2 (ja) 2011-02-16
CN100374563C (zh) 2008-03-12
CZ301570B6 (cs) 2010-04-21
JP2002517250A (ja) 2002-06-18
CZ301569B6 (cs) 2010-04-21
BR9911619B1 (pt) 2013-11-12
PE20000552A1 (es) 2000-07-14
PL348019A1 (en) 2002-05-06
ATE311193T1 (de) 2005-12-15
PL202161B1 (pl) 2009-06-30
SI1203813T1 (sl) 2006-06-30
HU228468B1 (en) 2013-03-28
PT1084251E (pt) 2005-03-31
PL202509B1 (pl) 2009-06-30

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