DE69929544D1 - Attenuierte Pestiviren - Google Patents

Attenuierte Pestiviren

Info

Publication number
DE69929544D1
DE69929544D1 DE69929544T DE69929544T DE69929544D1 DE 69929544 D1 DE69929544 D1 DE 69929544D1 DE 69929544 T DE69929544 T DE 69929544T DE 69929544 T DE69929544 T DE 69929544T DE 69929544 D1 DE69929544 D1 DE 69929544D1
Authority
DE
Germany
Prior art keywords
attenuated pestiviruses
pestiviruses
attenuated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69929544T
Other languages
English (en)
Other versions
DE69929544T2 (de
Inventor
Gregor Meyers
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Vetmedica GmbH
Boehringer Ingelheim Animal Health USA Inc
Original Assignee
Boehringer Ingelheim Vetmedica GmbH
Boehringer Ingelheim Vetmedica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica GmbH, Boehringer Ingelheim Vetmedica Inc filed Critical Boehringer Ingelheim Vetmedica GmbH
Application granted granted Critical
Publication of DE69929544D1 publication Critical patent/DE69929544D1/de
Publication of DE69929544T2 publication Critical patent/DE69929544T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/22—Ribonucleases RNAses, DNAses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/13—Tumour cells, irrespective of tissue of origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24311—Pestivirus, e.g. bovine viral diarrhea virus
    • C12N2770/24361—Methods of inactivation or attenuation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69929544T 1998-06-05 1999-05-26 Attenuierte Pestiviren Expired - Lifetime DE69929544T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98110356A EP0965639A1 (de) 1998-06-05 1998-06-05 Attenuierte Pestiviren
EP98110356 1998-06-05

Publications (2)

Publication Number Publication Date
DE69929544D1 true DE69929544D1 (de) 2006-04-13
DE69929544T2 DE69929544T2 (de) 2006-07-20

Family

ID=8232074

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69922953T Expired - Lifetime DE69922953T2 (de) 1998-06-05 1999-05-26 Attenuierte pestiviren
DE69929544T Expired - Lifetime DE69929544T2 (de) 1998-06-05 1999-05-26 Attenuierte Pestiviren
DE69928700T Expired - Lifetime DE69928700T2 (de) 1998-06-05 1999-05-26 Attenuierte Pestiviren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69922953T Expired - Lifetime DE69922953T2 (de) 1998-06-05 1999-05-26 Attenuierte pestiviren

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69928700T Expired - Lifetime DE69928700T2 (de) 1998-06-05 1999-05-26 Attenuierte Pestiviren

Country Status (23)

Country Link
EP (5) EP0965639A1 (de)
JP (3) JP4632540B2 (de)
KR (1) KR100637940B1 (de)
CN (2) CN101085346A (de)
AR (3) AR020084A1 (de)
AT (3) ATE286131T1 (de)
AU (1) AU769823C (de)
BR (2) BRPI9917787B1 (de)
CA (1) CA2330241C (de)
CO (1) CO5050392A1 (de)
CZ (3) CZ301494B6 (de)
DE (3) DE69922953T2 (de)
DK (3) DK1203813T3 (de)
ES (3) ES2257476T3 (de)
HU (3) HU228471B1 (de)
NZ (1) NZ509228A (de)
PE (1) PE20000552A1 (de)
PL (2) PL202509B1 (de)
PT (2) PT1203813E (de)
SI (3) SI1084251T1 (de)
SK (3) SK287626B6 (de)
TR (3) TR200103664T2 (de)
WO (1) WO1999064604A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7179473B2 (en) 1998-06-05 2007-02-20 Boehringer Ingelheim Vetmedica Gmbh Attenuated pestiviruses
EP1104676A1 (de) * 1999-11-30 2001-06-06 Boehringer Ingelheim Vetmedica Gmbh Sichere abgeschwächte Rinderdiarrhöeviren zur Verwendung in trächtigen Kühen
DK1149901T3 (da) * 2000-04-21 2006-07-31 Akzo Nobel Nv Mutanter af pestivirus og vacciner indeholdende disse
US7135561B2 (en) 2001-09-06 2006-11-14 Boehringer Ingelheim Vetmedica Gmbh Infectious bovine viral diarrhea virus clone
UY29915A1 (es) * 2005-11-15 2007-06-29 Boehringer Ingelheim Vetmed Vacuna combinada que comprende un virus atenuado de la diarrea viral bovina
AR069087A1 (es) 2007-10-29 2009-12-30 Boehringer Ingelheim Vetmed Cepa bacteriana de m. bovis atenuada avirulenta obtenida por pases, vacuna de micoplasma boris y metodos de uso de la misma
UY31930A (es) 2008-06-25 2010-01-29 Boheringer Ingelheim Pharma Kg Pestivirus atenuados recombinantes, en particular a csfv, bvdv o bdv atenuado recombinante
AU2009309041B2 (en) 2008-10-31 2016-02-04 Boehringer Ingelheim Animal Health USA Inc. Use of various antigens including antigens from mycoplasma bovis in multivalent vaccine composition
US8846054B2 (en) 2009-01-09 2014-09-30 Boehringer Ingelheim Vetmedica, Inc. Method of treating pregnant cows and/or heifers
UY32570A (es) 2009-04-24 2010-11-30 Boehringer Ingelheim Vetmed Vacuna viva modificada de mycoplasma bovis mejorada
CN101915837B (zh) * 2010-07-28 2013-07-03 中国兽医药品监察所 一种猪瘟兔化弱毒活疫苗效力检验方法
WO2012038454A1 (en) 2010-09-21 2012-03-29 Intervet International B.V. Bvdv vaccine
CN103882051B (zh) * 2014-03-20 2016-04-06 北京市农林科学院 一种检测猪瘟病毒抗体的elisa方法及检测试剂盒
KR20220009960A (ko) * 2019-04-18 2022-01-25 베링거 잉겔하임 베트메디카 (차이나) 코포레이션 리미티드 재조합 고전적 돼지 열병 바이러스

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE164885T1 (de) * 1986-01-27 1998-04-15 Syntro Corp Abgeschwächte herpesviren, herpesviren, die eine für aminosäuresequenzen kodierende fremd-dns enthalten, sowie impfstoffe, die diese enthalten

Also Published As

Publication number Publication date
SI1203812T1 (sl) 2006-04-30
JP5755265B2 (ja) 2015-07-29
ES2253457T3 (es) 2006-06-01
AU769823C (en) 2004-11-25
DE69928700T2 (de) 2006-06-22
DK1203813T3 (da) 2006-05-22
AR020084A1 (es) 2002-04-10
ATE286131T1 (de) 2005-01-15
NZ509228A (en) 2003-12-19
EP1614423A2 (de) 2006-01-11
BR9911619B1 (pt) 2013-11-12
CZ301494B6 (cs) 2010-03-24
EP1084251A2 (de) 2001-03-21
KR20010071406A (ko) 2001-07-28
ES2235488T3 (es) 2005-07-01
SK18232000A3 (sk) 2001-05-10
BR9911619A (pt) 2001-10-02
AR071880A2 (es) 2010-07-21
AU4369299A (en) 1999-12-30
DE69929544T2 (de) 2006-07-20
WO1999064604A3 (en) 2000-01-27
KR100637940B1 (ko) 2006-10-23
EP0965639A1 (de) 1999-12-22
CZ301569B6 (cs) 2010-04-21
EP1203812A3 (de) 2004-02-04
HU228469B1 (en) 2013-03-28
BRPI9917787B1 (pt) 2016-09-06
TR200103666T2 (tr) 2002-03-21
DK1084251T3 (da) 2005-04-11
JP2002517250A (ja) 2002-06-18
EP1203813B1 (de) 2006-01-25
CA2330241C (en) 2010-09-21
WO1999064604A2 (en) 1999-12-16
EP1203813A2 (de) 2002-05-08
EP1203813A3 (de) 2004-02-04
PT1084251E (pt) 2005-03-31
SK287014B6 (sk) 2009-09-07
CN100374563C (zh) 2008-03-12
EP1614423A3 (de) 2008-01-30
CN101085346A (zh) 2007-12-12
CO5050392A1 (es) 2001-06-27
EP1084251B1 (de) 2004-12-29
PE20000552A1 (es) 2000-07-14
PT1203813E (pt) 2006-06-30
JP2013099357A (ja) 2013-05-23
HUP0102707A2 (hu) 2001-11-28
CN1304452A (zh) 2001-07-18
SI1203813T1 (sl) 2006-06-30
EP1203812A2 (de) 2002-05-08
HU228471B1 (en) 2013-03-28
CZ301570B6 (cs) 2010-04-21
CA2330241A1 (en) 1999-12-16
SI1084251T1 (de) 2005-08-31
JP5247770B2 (ja) 2013-07-24
JP4632540B2 (ja) 2011-02-16
PL202161B1 (pl) 2009-06-30
DK1203812T3 (da) 2006-04-10
AR071881A2 (es) 2010-07-21
ATE316380T1 (de) 2006-02-15
DE69922953D1 (de) 2005-02-03
TR200103664T2 (tr) 2002-06-21
CZ20004533A3 (cs) 2001-07-11
HUP0102707A3 (en) 2008-04-28
AU769823B2 (en) 2004-02-05
JP2010259445A (ja) 2010-11-18
ATE311193T1 (de) 2005-12-15
PL348019A1 (en) 2002-05-06
HU228468B1 (en) 2013-03-28
TR200003622T2 (tr) 2001-06-21
SK287625B6 (sk) 2011-04-05
ES2257476T3 (es) 2006-08-01
EP1203812B1 (de) 2005-11-30
DE69928700D1 (de) 2006-01-05
SK287626B6 (sk) 2011-04-05
DE69922953T2 (de) 2005-05-19
PL202509B1 (pl) 2009-06-30

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Legal Events

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