TR199801179T2 - Yeni taksoitler, bunlar�n haz�rlanmalar� ve ila� bile�imleri. - Google Patents

Yeni taksoitler, bunlar�n haz�rlanmalar� ve ila� bile�imleri.

Info

Publication number
TR199801179T2
TR199801179T2 TR1998/01179T TR9801179T TR199801179T2 TR 199801179 T2 TR199801179 T2 TR 199801179T2 TR 1998/01179 T TR1998/01179 T TR 1998/01179T TR 9801179 T TR9801179 T TR 9801179T TR 199801179 T2 TR199801179 T2 TR 199801179T2
Authority
TR
Turkey
Prior art keywords
preparations
drug compositions
new taxoids
taxoids
new
Prior art date
Application number
TR1998/01179T
Other languages
English (en)
Turkish (tr)
Inventor
Bouchard Herve
Commer�on Alain
Original Assignee
Rhone-Poulenc Rorer S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone-Poulenc Rorer S.A. filed Critical Rhone-Poulenc Rorer S.A.
Publication of TR199801179T2 publication Critical patent/TR199801179T2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
TR1998/01179T 1995-12-22 1996-12-19 Yeni taksoitler, bunlar�n haz�rlanmalar� ve ila� bile�imleri. TR199801179T2 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9515379A FR2742751B1 (fr) 1995-12-22 1995-12-22 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
TR199801179T2 true TR199801179T2 (xx) 1998-10-21

Family

ID=9485871

Family Applications (1)

Application Number Title Priority Date Filing Date
TR1998/01179T TR199801179T2 (xx) 1995-12-22 1996-12-19 Yeni taksoitler, bunlar�n haz�rlanmalar� ve ila� bile�imleri.

Country Status (40)

Country Link
US (1) US5728849A (forum.php)
EP (1) EP0876362B1 (forum.php)
JP (1) JP3953106B2 (forum.php)
KR (1) KR100500351B1 (forum.php)
CN (1) CN1103766C (forum.php)
AR (1) AR005197A1 (forum.php)
AT (1) ATE250593T1 (forum.php)
AU (1) AU712597B2 (forum.php)
BG (1) BG63204B1 (forum.php)
BR (1) BR9612135A (forum.php)
CA (1) CA2238884C (forum.php)
CO (1) CO4520184A1 (forum.php)
CZ (1) CZ294972B6 (forum.php)
DE (1) DE69630145T2 (forum.php)
DK (1) DK0876362T3 (forum.php)
DZ (1) DZ2149A1 (forum.php)
EA (1) EA001533B1 (forum.php)
ES (1) ES2202490T3 (forum.php)
FR (1) FR2742751B1 (forum.php)
HU (1) HU225032B1 (forum.php)
IL (1) IL124994A (forum.php)
IN (4) IN186768B (forum.php)
MA (1) MA26412A1 (forum.php)
MX (1) MX9804688A (forum.php)
MY (1) MY113934A (forum.php)
NO (1) NO317358B1 (forum.php)
NZ (1) NZ324337A (forum.php)
OA (1) OA10700A (forum.php)
PE (1) PE25198A1 (forum.php)
PL (1) PL189311B1 (forum.php)
PT (1) PT876362E (forum.php)
RO (1) RO116194B1 (forum.php)
SK (1) SK282835B6 (forum.php)
TN (1) TNSN96169A1 (forum.php)
TR (1) TR199801179T2 (forum.php)
TW (1) TW371659B (forum.php)
UA (1) UA48205C2 (forum.php)
UY (1) UY24386A1 (forum.php)
WO (1) WO1997023473A1 (forum.php)
ZA (1) ZA9610737B (forum.php)

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GEP20043239B (en) 2000-02-02 2004-05-25 Florida State Univ Research Foundation Us C10 Carbonate Substituted Taxanes as Antitumor Agents
CA2435730C (en) * 2001-02-24 2011-03-29 Boehringer Ingelheim Pharma Gmbh & Co. Kg Xanthine derivatives, the preparation thereof and their use as pharmaceutical compositions
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
AU2003239511A1 (en) * 2003-05-20 2004-12-13 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
EP1669358A1 (en) * 2004-12-07 2006-06-14 Aventis Pharma S.A. Cytotoxic agents comprising new taxanes
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
EP1852108A1 (en) 2006-05-04 2007-11-07 Boehringer Ingelheim Pharma GmbH & Co.KG DPP IV inhibitor formulations
CN102838599A (zh) 2006-05-04 2012-12-26 贝林格尔.英格海姆国际有限公司 多晶型
PE20080251A1 (es) 2006-05-04 2008-04-25 Boehringer Ingelheim Int Usos de inhibidores de dpp iv
US20080207743A1 (en) * 2007-02-28 2008-08-28 Rodger Lamb Biologically Active Taxane Analogs and Methods of Treatment
MX2010001821A (es) * 2007-08-17 2010-03-10 Boehringer Ingelheim Int Derivados de purina para uso en el tratamiento de enfermedades relacionadas con fap.
PE20140960A1 (es) 2008-04-03 2014-08-15 Boehringer Ingelheim Int Formulaciones que comprenden un inhibidor de dpp4
PE20100156A1 (es) * 2008-06-03 2010-02-23 Boehringer Ingelheim Int Tratamiento de nafld
BRPI0916997A2 (pt) 2008-08-06 2020-12-15 Boehringer Ingelheim International Gmbh Inibidor de dpp-4 e seu uso
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
CA2735562C (en) * 2008-08-15 2017-10-17 Boehringer Ingelheim International Gmbh Dpp-4 inhibitors for wound healing
WO2010029089A2 (en) 2008-09-10 2010-03-18 Boehringer Ingelheim International Gmbh Combination therapy for the treatment of diabetes and related conditions
US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
MX2011006713A (es) 2008-12-23 2011-07-13 Boehringer Ingelheim Int Formas salinas de compuesto organico.
AR074990A1 (es) 2009-01-07 2011-03-02 Boehringer Ingelheim Int Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina
PH12012501037A1 (en) 2009-11-27 2013-01-14 Boehringer Ingelheim Int Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
JP6034781B2 (ja) 2010-05-05 2016-11-30 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 併用療法
KR20130093012A (ko) 2010-06-24 2013-08-21 베링거 인겔하임 인터내셔날 게엠베하 당뇨병 요법
AR083878A1 (es) 2010-11-15 2013-03-27 Boehringer Ingelheim Int Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
DK3517539T3 (en) 2011-07-15 2023-01-16 Boehringer Ingelheim Int Farmaceutiske sammensætninger til behandling af type i og type ii diabetes
US9555001B2 (en) 2012-03-07 2017-01-31 Boehringer Ingelheim International Gmbh Pharmaceutical composition and uses thereof
JP6224084B2 (ja) 2012-05-14 2017-11-01 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 糸球体上皮細胞関連障害及び／又はネフローゼ症候群の治療に用いるｄｐｐ−４阻害薬としてのキサンチン誘導体
EP2849754B1 (en) 2012-05-14 2022-09-14 Boehringer Ingelheim International GmbH Linagliptin, a xanthine derivative as dpp-4 inhibitor, for use in the treatment of sirs and/or sepsis
WO2013174767A1 (en) 2012-05-24 2013-11-28 Boehringer Ingelheim International Gmbh A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
ES2701076T3 (es) 2012-11-24 2019-02-20 Hangzhou Dac Biotech Co Ltd Enlazadores hidrofílicos y sus usos para la conjugación de fármacos a las moléculas que se unen a las células
FR3010839B1 (fr) * 2013-09-17 2017-04-21 Schneider Electric Ind Sas Dispositif de raccordement electrique d'au moins un conducteur dans une borne appartenant a un appareil electrique
JP6615109B2 (ja) 2014-02-28 2019-12-04 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング Ｄｐｐ−４阻害薬の医学的使用
AU2014384434B2 (en) 2014-02-28 2016-11-03 Hangzhou Dac Biotech Co., Ltd Charged linkers and their uses for conjugation
WO2015151081A2 (en) 2015-07-12 2015-10-08 Suzhou M-Conj Biotech Co., Ltd Bridge linkers for conjugation of a cell-binding molecule
US9839687B2 (en) 2015-07-15 2017-12-12 Suzhou M-Conj Biotech Co., Ltd. Acetylenedicarboxyl linkers and their uses in specific conjugation of a cell-binding molecule
JP2019517542A (ja) 2016-06-10 2019-06-24 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング リナグリプチンおよびメトホルミンの組合せ
AU2016429272A1 (en) 2016-11-14 2019-05-02 Hangzhou Dac Biotech Co., Ltd. Conjugation linkers, cell binding molecule-drug conjugates containing the likers, methods of making and uses such conjugates with the linkers
WO2022078524A2 (en) 2021-11-03 2022-04-21 Hangzhou Dac Biotech Co., Ltd. Specific conjugation of an antibody

Family Cites Families (7)

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RU2017724C1 (ru) * 1990-07-12 1994-08-15 Дзе Юниверсити оф Канзас Способ получения производных таксола
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
RU2059631C1 (ru) * 1991-11-29 1996-05-10 Дзе Юниверсити оф Канзас Производные таксола и фармацевтическая композиция, обладающая противоопухолевой активностью
DK0639186T3 (da) * 1992-04-17 1999-12-13 Abbott Lab Taxolderivater
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
MX9307777A (es) * 1992-12-15 1994-07-29 Upjohn Co 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN.

Also Published As

Publication number Publication date
KR100500351B1 (ko) 2005-12-21
BR9612135A (pt) 1999-07-13
HU225032B1 (en) 2006-05-29
PT876362E (pt) 2004-02-27
IN188470B (forum.php) 2002-09-28
IN188469B (forum.php) 2002-09-28
EP0876362A1 (fr) 1998-11-11
CA2238884C (fr) 2007-02-06
DE69630145D1 (de) 2003-10-30
JP2000502671A (ja) 2000-03-07
IN188680B (forum.php) 2002-10-26
UY24386A1 (es) 2001-08-27
CA2238884A1 (fr) 1997-07-03
KR19990076680A (ko) 1999-10-15
AR005197A1 (es) 1999-04-14
SK85398A3 (en) 1998-11-04
PL327405A1 (en) 1998-12-07
NO982580D0 (no) 1998-06-05
OA10700A (fr) 2002-11-27
BG63204B1 (bg) 2001-06-29
EA199800588A1 (ru) 1998-12-24
FR2742751B1 (fr) 1998-01-30
ZA9610737B (en) 1997-06-27
NZ324337A (en) 2000-03-27
CZ196198A3 (cs) 1998-09-16
HUP9904046A1 (hu) 2001-04-28
RO116194B1 (ro) 2000-11-30
EA001533B1 (ru) 2001-04-23
ES2202490T3 (es) 2004-04-01
TW371659B (en) 1999-10-11
JP3953106B2 (ja) 2007-08-08
IL124994A0 (en) 1999-01-26
WO1997023473A1 (fr) 1997-07-03
PE25198A1 (es) 1998-05-10
CN1103766C (zh) 2003-03-26
MA26412A1 (fr) 2004-12-20
FR2742751A1 (fr) 1997-06-27
IN186768B (forum.php) 2001-11-03
UA48205C2 (uk) 2002-08-15
TNSN96169A1 (fr) 2005-03-15
HUP9904046A3 (en) 2001-08-28
AU1180997A (en) 1997-07-17
ATE250593T1 (de) 2003-10-15
NO317358B1 (no) 2004-10-18
DK0876362T3 (da) 2004-02-02
NO982580L (no) 1998-06-05
MX9804688A (es) 1998-10-31
SK282835B6 (sk) 2002-12-03
DE69630145T2 (de) 2004-07-15
CN1205697A (zh) 1999-01-20
US5728849A (en) 1998-03-17
BG102569A (en) 1999-04-30
EP0876362B1 (fr) 2003-09-24
CO4520184A1 (es) 1997-10-15
AU712597B2 (en) 1999-11-11
HK1017895A1 (en) 1999-12-03
PL189311B1 (pl) 2005-07-29
DZ2149A1 (fr) 2002-10-23
MY113934A (en) 2002-06-29
CZ294972B6 (cs) 2005-04-13
IL124994A (en) 2000-12-06

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