TR199701048T1 - Ba��rsak enfeksiyonlar�na kar�� ila�lar�n haz�rlanmas�nda fumagilol�n ve t�revlerinin kullan�m�. - Google Patents

Ba��rsak enfeksiyonlar�na kar�� ila�lar�n haz�rlanmas�nda fumagilol�n ve t�revlerinin kullan�m�.

Info

Publication number
TR199701048T1
TR199701048T1 TR97/01048T TR9701048T TR199701048T1 TR 199701048 T1 TR199701048 T1 TR 199701048T1 TR 97/01048 T TR97/01048 T TR 97/01048T TR 9701048 T TR9701048 T TR 9701048T TR 199701048 T1 TR199701048 T1 TR 199701048T1
Authority
TR
Turkey
Prior art keywords
fumagilol
rlanmas
revlerinin
kullan
enfeksiyonlar
Prior art date
Application number
TR97/01048T
Other languages
English (en)
Turkish (tr)
Inventor
Molina Jean-Michel
Derouin Francis
Original Assignee
Sanofi
Assistance Publique-Hopitaux De Paris
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi, Assistance Publique-Hopitaux De Paris filed Critical Sanofi
Publication of TR199701048T1 publication Critical patent/TR199701048T1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/336—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
TR97/01048T 1995-03-27 1996-03-26 Ba��rsak enfeksiyonlar�na kar�� ila�lar�n haz�rlanmas�nda fumagilol�n ve t�revlerinin kullan�m�. TR199701048T1 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9503549 1995-03-27

Publications (1)

Publication Number Publication Date
TR199701048T1 true TR199701048T1 (xx) 1998-01-21

Family

ID=9477436

Family Applications (1)

Application Number Title Priority Date Filing Date
TR97/01048T TR199701048T1 (xx) 1995-03-27 1996-03-26 Ba��rsak enfeksiyonlar�na kar�� ila�lar�n haz�rlanmas�nda fumagilol�n ve t�revlerinin kullan�m�.

Country Status (25)

Country Link
US (1) US5900431A (enEXAMPLES)
EP (1) EP0817626B1 (enEXAMPLES)
JP (1) JP3260378B2 (enEXAMPLES)
KR (1) KR100286920B1 (enEXAMPLES)
CN (1) CN1072485C (enEXAMPLES)
AP (1) AP646A (enEXAMPLES)
AT (1) ATE172641T1 (enEXAMPLES)
AU (1) AU706161B2 (enEXAMPLES)
CA (1) CA2216623C (enEXAMPLES)
CZ (1) CZ286821B6 (enEXAMPLES)
DE (1) DE69600879T2 (enEXAMPLES)
DK (1) DK0817626T3 (enEXAMPLES)
EA (1) EA000150B1 (enEXAMPLES)
ES (1) ES2128846T3 (enEXAMPLES)
FR (1) FR06C0014I2 (enEXAMPLES)
HU (1) HU224028B1 (enEXAMPLES)
IS (1) IS2048B (enEXAMPLES)
NO (1) NO315968B1 (enEXAMPLES)
NZ (1) NZ304906A (enEXAMPLES)
OA (1) OA10515A (enEXAMPLES)
PL (1) PL183378B1 (enEXAMPLES)
SK (1) SK283883B6 (enEXAMPLES)
TR (1) TR199701048T1 (enEXAMPLES)
UA (1) UA41446C2 (enEXAMPLES)
WO (1) WO1996030010A2 (enEXAMPLES)

Families Citing this family (36)

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UA41446C2 (uk) * 1995-03-27 2001-09-17 Санофі - Сінтелабо Застосування фумагілолу та його похідних для одержання ліків, призначених для боротьби з кишковими інфекціями, та фармацевтична композиція на їх основі
EP0799616A1 (en) * 1996-04-01 1997-10-08 Takeda Chemical Industries, Ltd. Oral composition comprising a fumagillol derivative
DE60034770T2 (de) * 1999-02-26 2008-04-30 Sanofi-Aventis Stabile fumagillin-formulierung
JP3265394B1 (ja) * 2001-03-14 2002-03-11 泰三 矢野 アクリル系樹脂手袋
DE10341887A1 (de) * 2003-09-09 2005-03-31 Leopold Kostal Gmbh & Co. Kg Elektrisches Schaltermodul
FR2886855B1 (fr) * 2005-06-08 2009-07-17 Agronomique Inst Nat Rech Utilisation de la fumagilline et de ses derives pour augmenter la biodisponibilite des lactones macrocyliques
BRPI0820229A2 (pt) * 2007-11-28 2017-05-09 A Stevenson Cheri conjugados de análogos de fumagilina biodegradáveis biocompatíveis
CA2731020A1 (en) * 2008-07-18 2010-01-21 Zafgen, Inc. Use of antiangiogenic fumagillins in the treatment of obesity
WO2010065883A2 (en) 2008-12-04 2010-06-10 Zafgen Corporation Method of treating an overweight or obese subject
US20120004162A1 (en) 2008-12-04 2012-01-05 Vath James E Methods of Treating an Overweight or Obese Subject
MX337575B (es) 2009-10-09 2016-03-10 Zafgen Corp Compuestos de sulfona y métodos para lafabricación y uso de éstos.
WO2011085198A1 (en) 2010-01-08 2011-07-14 Zafgen Corporation Metap-2 inhibitor for use in treating benign prostatic hypertrophy (bph)
CN102791699B (zh) 2010-01-08 2016-04-06 扎夫根公司 烟曲霉醇型化合物和其制造和使用方法
US20130266578A1 (en) 2010-04-07 2013-10-10 Thomas E. Hughes Methods of treating an overweight subject
JP5913310B2 (ja) 2010-07-22 2016-04-27 ザフゲン，インコーポレイテッド 三環式化合物ならびにその作製および使用方法
PH12013500934A1 (en) 2010-11-09 2022-10-24 Zafgen Inc Crystalline solids of a metap-2 inhibitor and methods of making and using same
KR20140009273A (ko) 2010-11-29 2014-01-22 자프겐 인크. 6-o-(4-디메틸아미노에톡시)신나모일 푸마길롤의 비-일일 투여를 사용하는 비만의 치료
MX344238B (es) 2011-01-26 2016-12-07 Zafgen Inc Compuestos de tetrazol y métodos para preparar y usar los mismos.
BR112013023056A2 (pt) 2011-03-08 2018-10-09 Zafgen Inc derivados de oxaespiro [2,5] octano e análogos
JP6062423B2 (ja) 2011-05-06 2017-01-18 ザフゲン，インコーポレイテッド 部分飽和三環式化合物ならびにその製造および使用方法
AU2012253760B2 (en) 2011-05-06 2016-02-04 Zafgen, Inc. Tricyclic pyrazole sulfonamide compounds and methods of making and using same
MX343687B (es) 2011-05-06 2016-11-16 Zafgen Inc Compuestos sulfonamida tricíclica y métodos para su fabricación y uso.
EP2763671A2 (en) 2011-10-03 2014-08-13 Zafgen, Inc. Methods of treating age related disorders
WO2013109739A1 (en) 2012-01-18 2013-07-25 Zafgen, Inc. Tricyclic sulfonamide compounds and methods of making and using same
KR20140112566A (ko) 2012-01-18 2014-09-23 자프겐 인크. 삼환식 설폰 화합물 그리고 그의 제조방법 및 그를 이용하는 방법
WO2013169727A1 (en) 2012-05-07 2013-11-14 Zafgen, Inc. Polymorphic salt of the oxalate salt of 6 - o - ( 4 - dimethylaminoethoxy) cinnarnoyl fumagillol and methods of making and using same
JP2015516426A (ja) 2012-05-08 2015-06-11 ザフゲン，インコーポレイテッド ＭｅｔＡＰ２阻害剤による視床下部性肥満症の治療
AU2013259620B2 (en) 2012-05-09 2017-05-18 Zafgen, Inc. Fumigillol type compounds and methods of making and using same
JP2015536981A (ja) 2012-11-05 2015-12-24 ザフゲン，インコーポレイテッド 三環式化合物ならびにその製造および使用方法
CN104918928A (zh) 2012-11-05 2015-09-16 扎夫根股份有限公司 三环化合物及其制备方法和用途
WO2014071368A1 (en) 2012-11-05 2014-05-08 Zafgen, Inc. Methods of treating liver diseases
AU2014236528A1 (en) 2013-03-14 2015-09-24 Zafgen, Inc. Methods of treating renal disease and other disorders
AR105671A1 (es) 2015-08-11 2017-10-25 Zafgen Inc Compuestos heterocíclicos de fumagillol y sus métodos de elaboración y uso
CN106432255A (zh) 2015-08-11 2017-02-22 扎夫根公司 烟曲霉素醇螺环化合物和制备和使用其的方法
CN106591389B (zh) * 2015-10-15 2019-10-11 中国科学院微生物研究所 一种利用烟曲霉菌生产烟曲霉素的方法
CN105622593B (zh) * 2016-02-25 2018-06-26 中国农业科学院蜜蜂研究所 一种烟曲霉素的提取方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2791530A (en) * 1953-08-31 1957-05-07 Abbott Lab Stabilized fumagillin compositions
JPH0629278B2 (ja) * 1985-06-26 1994-04-20 藤沢薬品工業株式会社 オキサスピロオクタン化合物
US5135920A (en) * 1988-11-16 1992-08-04 Takeda Chemical Industries, Ltd. Angiostatic agents
EP0541716A1 (en) * 1990-07-27 1993-05-19 Repligen Corporation Novel methods and compositions for treatment of angiogenic diseases
US5328930A (en) * 1993-03-01 1994-07-12 Emory University Treatment of microsporidial and acanthamoeba keratoconjunctivitis with topical fumagillin
UA41446C2 (uk) * 1995-03-27 2001-09-17 Санофі - Сінтелабо Застосування фумагілолу та його похідних для одержання ліків, призначених для боротьби з кишковими інфекціями, та фармацевтична композиція на їх основі
EP0799616A1 (en) * 1996-04-01 1997-10-08 Takeda Chemical Industries, Ltd. Oral composition comprising a fumagillol derivative
CA2210600A1 (en) * 1996-07-17 1998-01-17 Takashi Houkan Inhibitor of tumor metastasis or recurrence
WO1998005293A2 (en) * 1996-08-02 1998-02-12 The Children's Medical Center Corporation Method of regulating the female reproductive system through angiogenesis inhibitors

Also Published As

Publication number Publication date
AU5278696A (en) 1996-10-16
EP0817626A2 (fr) 1998-01-14
HUP9801220A2 (hu) 1999-09-28
NO315968B1 (no) 2003-11-24
CN1072485C (zh) 2001-10-10
DE69600879T2 (de) 1999-06-02
IS2048B (is) 2005-09-15
EA000150B1 (ru) 1998-10-29
SK283883B6 (sk) 2004-04-06
CA2216623A1 (en) 1996-10-03
FR06C0014I1 (enEXAMPLES) 2006-11-17
KR19980703271A (ko) 1998-10-15
PL183378B1 (pl) 2002-06-28
US5900431A (en) 1999-05-04
MX9707150A (es) 1998-07-31
ATE172641T1 (de) 1998-11-15
JPH11506421A (ja) 1999-06-08
JP3260378B2 (ja) 2002-02-25
NO974466D0 (no) 1997-09-26
AU706161B2 (en) 1999-06-10
AP646A (en) 1998-04-27
OA10515A (fr) 2002-04-24
NO974466L (no) 1997-09-26
WO1996030010A2 (fr) 1996-10-03
SK130797A3 (en) 1998-03-04
ES2128846T3 (es) 1999-05-16
KR100286920B1 (ko) 2001-04-16
CN1179715A (zh) 1998-04-22
EP0817626B1 (fr) 1998-10-28
PL322470A1 (en) 1998-02-02
AP9701092A0 (en) 1997-10-31
WO1996030010A3 (fr) 1996-11-28
CZ286821B6 (en) 2000-07-12
EA199700267A1 (ru) 1998-04-30
HU224028B1 (hu) 2005-05-30
HUP9801220A3 (en) 2001-10-29
NZ304906A (en) 1999-06-29
DK0817626T3 (da) 1999-07-12
CA2216623C (en) 2005-05-31
UA41446C2 (uk) 2001-09-17
FR06C0014I2 (enEXAMPLES) 2006-12-29
CZ304997A3 (en) 1997-12-17
DE69600879D1 (de) 1998-12-03
IS4557A (is) 1997-09-11

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