SU743581A3 - Способ получени производных 9-хлорпреднизолона - Google Patents

Способ получени производных 9-хлорпреднизолона Download PDF

Info

Publication number
SU743581A3
SU743581A3 SU772526300A SU2526300A SU743581A3 SU 743581 A3 SU743581 A3 SU 743581A3 SU 772526300 A SU772526300 A SU 772526300A SU 2526300 A SU2526300 A SU 2526300A SU 743581 A3 SU743581 A3 SU 743581A3
Authority
SU
USSR - Soviet Union
Prior art keywords
dione
hydroxy
pregnadien
treated
chloro
Prior art date
Application number
SU772526300A
Other languages
English (en)
Russian (ru)
Inventor
Аннен Клаус
Лаурент Хенри
Хофмайстер Хельмут
Вихерт Рудольф
Вендт Ханс
Фридрих Капп Иоахим
Original Assignee
Шеринг Аг (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2645105A external-priority patent/DE2645105C2/de
Priority claimed from DE19772742982 external-priority patent/DE2742982C2/de
Application filed by Шеринг Аг (Фирма) filed Critical Шеринг Аг (Фирма)
Application granted granted Critical
Publication of SU743581A3 publication Critical patent/SU743581A3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SU772526300A 1976-10-04 1977-10-04 Способ получени производных 9-хлорпреднизолона SU743581A3 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2645105A DE2645105C2 (de) 1976-10-04 1976-10-04 Derivate des 9-Chlorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Präparat
DE19772742982 DE2742982C2 (de) 1977-09-21 1977-09-21 9-Chlorprednisolon-Derivate, Verfahren zu deren Herstellung und diese enthaltendes pharmazeutisches Präparat

Publications (1)

Publication Number Publication Date
SU743581A3 true SU743581A3 (ru) 1980-06-25

Family

ID=25770978

Family Applications (2)

Application Number Title Priority Date Filing Date
SU772526300A SU743581A3 (ru) 1976-10-04 1977-10-04 Способ получени производных 9-хлорпреднизолона
SU782672298A SU751327A3 (ru) 1976-10-04 1978-10-13 Способ получени производных 9-хлорпреднизолона

Family Applications After (1)

Application Number Title Priority Date Filing Date
SU782672298A SU751327A3 (ru) 1976-10-04 1978-10-13 Способ получени производных 9-хлорпреднизолона

Country Status (21)

Country Link
JP (1) JPS5359654A (de)
AT (1) AT358202B (de)
CH (4) CH630098A5 (de)
DK (1) DK438277A (de)
ES (1) ES462887A1 (de)
FI (1) FI58645C (de)
FR (1) FR2366313A1 (de)
GB (1) GB1594852A (de)
GR (1) GR73041B (de)
HU (1) HU179593B (de)
IE (1) IE45877B1 (de)
IL (1) IL53030A (de)
IT (1) IT1113623B (de)
LU (1) LU78223A1 (de)
NL (1) NL7710869A (de)
NO (1) NO148597C (de)
NZ (1) NZ185295A (de)
PL (1) PL110392B1 (de)
PT (1) PT67109B (de)
SE (1) SE431655B (de)
SU (2) SU743581A3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853785A1 (de) * 1978-12-11 1980-06-19 Schering Ag Neue prednison-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung
JPH0374245A (ja) * 1989-08-12 1991-03-28 Mk Seiko Co Ltd 洗車機
JP5747391B2 (ja) 2010-03-26 2015-07-15 ガルデルマ・リサーチ・アンド・デヴェロップメント 紅斑の安全かつ有効な治療のための改善された方法および組成物
BR112014009210A2 (pt) 2011-10-19 2017-04-18 Galderma Sa método para a redução da vermelhidão facial cutânea
CN106632561A (zh) * 2016-12-16 2017-05-10 广州仁恒医药科技股份有限公司 一种二氟泼尼酯的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH429716A (de) * 1961-06-24 1967-02-15 Vismara Francesco Spa Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride

Also Published As

Publication number Publication date
GR73041B (de) 1984-01-26
CH632278A5 (en) 1982-09-30
FI58645B (fi) 1980-11-28
DK438277A (da) 1978-04-05
PT67109B (de) 1979-03-14
HU179593B (en) 1982-11-29
IE45877B1 (en) 1982-12-15
SE431655B (sv) 1984-02-20
JPS5359654A (en) 1978-05-29
ATA703577A (de) 1980-01-15
FR2366313A1 (fr) 1978-04-28
CH632772A5 (en) 1982-10-29
GB1594852A (en) 1981-08-05
CH630098A5 (en) 1982-05-28
IL53030A (en) 1982-11-30
NO773362L (no) 1978-04-05
PT67109A (de) 1977-11-01
PL201161A1 (pl) 1979-01-29
SU751327A3 (ru) 1980-07-23
NO148597B (no) 1983-08-01
FR2366313B1 (de) 1980-02-01
CH631997A5 (en) 1982-09-15
NO148597C (no) 1983-11-09
FI772922A (fi) 1978-04-05
PL110392B1 (en) 1980-07-31
NL7710869A (nl) 1978-04-06
IL53030A0 (en) 1977-11-30
NZ185295A (en) 1980-04-28
IT1113623B (it) 1986-01-20
JPS6129960B2 (de) 1986-07-10
LU78223A1 (de) 1978-02-01
SE7711039L (sv) 1978-04-05
IE45877L (en) 1978-04-04
FI58645C (fi) 1981-03-10
AT358202B (de) 1980-08-25
ES462887A1 (es) 1978-12-16

Similar Documents

Publication Publication Date Title
US4290962A (en) Novel hydrocortisone derivative
DE2340591A1 (de) Steroidverbindungen
NO162506B (no) Anordning for loefte fisk.
SU743581A3 (ru) Способ получени производных 9-хлорпреднизолона
US4427671A (en) Steroids esterified in position 17 and thioesterified in position 21, a process for preparing them and their use as medicaments
JPH033679B2 (de)
US2966486A (en) 16alpha, 17alpha-substituted methylene dioxy ethers of steroids of the pregnane series and method of preparing the same
GB1594371A (en) Corticoids
EP0149222B1 (de) Neue 6alpha, 16alpha-Dimethylkortikoide
SU880253A3 (ru) Способ получени кортикоидов
SU902668A3 (ru) Способ получени производных 9-хлорпреднизолона
FI62317C (fi) Foerfarande foer framstaellning av farmakologiskt vaerdefulla d-homosteroider
DE1493178C3 (de) 6 alpha-Fluor-16 alpha-methyl-1,4pregnadien-3,20-dion-derivate und Verfahren zu ihrer Herstellung
US3651049A (en) 17alpha 21 alkenylidene dioxy derivatives of pregnane and process for preparation thereof
GB1603281A (en) Derivatives of 9-fluoroprednisolone
CA2139549A1 (en) Corticoid derivatives and pharmaceutical and cosmetic compositions
EP0164298A2 (de) Neue 6alpha-Methyl-D-homo-kortikoide
IE43979B1 (en) 21-acetals and mixed acetals of steroidal 21-aldehydes,intermediates and methods of preparation
US3254100A (en) Hydrocortisone 21-(lower alkane) sulfonate
DE1793270A1 (de) 16alpha,17alpha-Methylensteroidverbindungen und Verfahren zu ihrer Herstellung
US3377343A (en) 2', 2'-bistrifluoromethyloxetano(3', 4'; 16alpha, 17alpha)derivatives of the pregnane series
GB1589585A (en) 12a-halocorticoids
KR820002025B1 (ko) 하이드로 코르티죤 유도체의 제조방법
US3819604A (en) 6,9,21-trihalogenosteroids
US3313807A (en) 5'-substituted steroidal isoxazoles of the pregnane series