JPS5359654A - Novel derivatives of 99 chlorpredonisolone * production of same and pharmaceutical agent containing the same with strong antiiinflammatory acti1on - Google Patents
Novel derivatives of 99 chlorpredonisolone * production of same and pharmaceutical agent containing the same with strong antiiinflammatory acti1onInfo
- Publication number
- JPS5359654A JPS5359654A JP11940077A JP11940077A JPS5359654A JP S5359654 A JPS5359654 A JP S5359654A JP 11940077 A JP11940077 A JP 11940077A JP 11940077 A JP11940077 A JP 11940077A JP S5359654 A JPS5359654 A JP S5359654A
- Authority
- JP
- Japan
- Prior art keywords
- same
- chlorpredonisolone
- antiiinflammatory
- acti1on
- strong
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2645105A DE2645105C2 (en) | 1976-10-04 | 1976-10-04 | Derivatives of 9-chlorprednisolone, process for their preparation and pharmaceutical preparation containing them |
| DE19772742982 DE2742982C2 (en) | 1977-09-21 | 1977-09-21 | 9-chlorprednisolone derivatives, process for their production and pharmaceutical preparation containing them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5359654A true JPS5359654A (en) | 1978-05-29 |
| JPS6129960B2 JPS6129960B2 (en) | 1986-07-10 |
Family
ID=25770978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP11940077A Granted JPS5359654A (en) | 1976-10-04 | 1977-10-04 | Novel derivatives of 99 chlorpredonisolone * production of same and pharmaceutical agent containing the same with strong antiiinflammatory acti1on |
Country Status (21)
| Country | Link |
|---|---|
| JP (1) | JPS5359654A (en) |
| AT (1) | AT358202B (en) |
| CH (4) | CH630098A5 (en) |
| DK (1) | DK438277A (en) |
| ES (1) | ES462887A1 (en) |
| FI (1) | FI58645C (en) |
| FR (1) | FR2366313A1 (en) |
| GB (1) | GB1594852A (en) |
| GR (1) | GR73041B (en) |
| HU (1) | HU179593B (en) |
| IE (1) | IE45877B1 (en) |
| IL (1) | IL53030A (en) |
| IT (1) | IT1113623B (en) |
| LU (1) | LU78223A1 (en) |
| NL (1) | NL7710869A (en) |
| NO (1) | NO148597C (en) |
| NZ (1) | NZ185295A (en) |
| PL (1) | PL110392B1 (en) |
| PT (1) | PT67109B (en) |
| SE (1) | SE431655B (en) |
| SU (2) | SU743581A3 (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2853785A1 (en) * | 1978-12-11 | 1980-06-19 | Schering Ag | NEW PREDNISON DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS AND THE USE THEREOF |
| JPH0374245A (en) * | 1989-08-12 | 1991-03-28 | Mk Seiko Co Ltd | Car washing machine |
| US8513247B2 (en) | 2010-03-26 | 2013-08-20 | Galderma Laboratories, L.P. | Methods and compositions for safe and effective treatment of erythema |
| US9744168B2 (en) | 2011-10-19 | 2017-08-29 | Galderma Laboratories, Inc. | Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors |
| CN106632561A (en) * | 2016-12-16 | 2017-05-10 | 广州仁恒医药科技股份有限公司 | Method for preparing difluprednate |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1195748B (en) * | 1961-06-24 | 1965-07-01 | Vismara Francesco Spa | Process for the preparation of 1'-substituted 17alpha, 21- (1'-alkoxy) -methylenedioxysteriodes |
| DE2055221A1 (en) * | 1970-11-10 | 1972-05-18 | Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) | 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride |
-
1977
- 1977-09-29 NZ NZ185295A patent/NZ185295A/en unknown
- 1977-09-30 CH CH1199177A patent/CH630098A5/en not_active IP Right Cessation
- 1977-09-30 PL PL1977201161A patent/PL110392B1/en unknown
- 1977-09-30 IL IL53030A patent/IL53030A/en unknown
- 1977-10-03 IE IE2011/77A patent/IE45877B1/en unknown
- 1977-10-03 LU LU78223A patent/LU78223A1/xx unknown
- 1977-10-03 PT PT67109A patent/PT67109B/en unknown
- 1977-10-03 HU HU77SCHE624A patent/HU179593B/en unknown
- 1977-10-03 GB GB40924/77A patent/GB1594852A/en not_active Expired
- 1977-10-03 SE SE7711039A patent/SE431655B/en not_active IP Right Cessation
- 1977-10-03 GR GR54473A patent/GR73041B/el unknown
- 1977-10-03 AT AT703577A patent/AT358202B/en not_active IP Right Cessation
- 1977-10-03 NO NO773362A patent/NO148597C/en unknown
- 1977-10-03 IT IT28201/77A patent/IT1113623B/en active
- 1977-10-04 DK DK438277A patent/DK438277A/en not_active Application Discontinuation
- 1977-10-04 FI FI772922A patent/FI58645C/en not_active IP Right Cessation
- 1977-10-04 NL NL7710869A patent/NL7710869A/en not_active Application Discontinuation
- 1977-10-04 JP JP11940077A patent/JPS5359654A/en active Granted
- 1977-10-04 FR FR7729740A patent/FR2366313A1/en active Granted
- 1977-10-04 SU SU772526300A patent/SU743581A3/en active
- 1977-10-04 ES ES462887A patent/ES462887A1/en not_active Expired
-
1978
- 1978-10-13 SU SU782672298A patent/SU751327A3/en active
-
1981
- 1981-09-08 CH CH579381A patent/CH632278A5/en not_active IP Right Cessation
- 1981-09-08 CH CH579481A patent/CH631997A5/en not_active IP Right Cessation
- 1981-09-08 CH CH579281A patent/CH632772A5/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SU751327A3 (en) | 1980-07-23 |
| FR2366313B1 (en) | 1980-02-01 |
| IE45877B1 (en) | 1982-12-15 |
| SE431655B (en) | 1984-02-20 |
| DK438277A (en) | 1978-04-05 |
| CH631997A5 (en) | 1982-09-15 |
| JPS6129960B2 (en) | 1986-07-10 |
| FI772922A (en) | 1978-04-05 |
| IL53030A0 (en) | 1977-11-30 |
| PL110392B1 (en) | 1980-07-31 |
| NO148597B (en) | 1983-08-01 |
| IE45877L (en) | 1978-04-04 |
| NL7710869A (en) | 1978-04-06 |
| PT67109A (en) | 1977-11-01 |
| FI58645C (en) | 1981-03-10 |
| CH632278A5 (en) | 1982-09-30 |
| SE7711039L (en) | 1978-04-05 |
| PL201161A1 (en) | 1979-01-29 |
| ATA703577A (en) | 1980-01-15 |
| GR73041B (en) | 1984-01-26 |
| LU78223A1 (en) | 1978-02-01 |
| NZ185295A (en) | 1980-04-28 |
| PT67109B (en) | 1979-03-14 |
| CH632772A5 (en) | 1982-10-29 |
| HU179593B (en) | 1982-11-29 |
| SU743581A3 (en) | 1980-06-25 |
| FI58645B (en) | 1980-11-28 |
| NO148597C (en) | 1983-11-09 |
| GB1594852A (en) | 1981-08-05 |
| CH630098A5 (en) | 1982-05-28 |
| IL53030A (en) | 1982-11-30 |
| IT1113623B (en) | 1986-01-20 |
| AT358202B (en) | 1980-08-25 |
| NO773362L (en) | 1978-04-05 |
| FR2366313A1 (en) | 1978-04-28 |
| ES462887A1 (en) | 1978-12-16 |
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