FR2366313A1 - PREDNISOLONE 9-CHLORO DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING IT - Google Patents

PREDNISOLONE 9-CHLORO DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING IT

Info

Publication number
FR2366313A1
FR2366313A1 FR7729740A FR7729740A FR2366313A1 FR 2366313 A1 FR2366313 A1 FR 2366313A1 FR 7729740 A FR7729740 A FR 7729740A FR 7729740 A FR7729740 A FR 7729740A FR 2366313 A1 FR2366313 A1 FR 2366313A1
Authority
FR
France
Prior art keywords
prednisolone
products containing
medicinal products
chloro derivatives
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7729740A
Other languages
French (fr)
Other versions
FR2366313B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2645105A external-priority patent/DE2645105C2/en
Priority claimed from DE19772742982 external-priority patent/DE2742982C2/en
Application filed by Schering AG filed Critical Schering AG
Publication of FR2366313A1 publication Critical patent/FR2366313A1/en
Application granted granted Critical
Publication of FR2366313B1 publication Critical patent/FR2366313B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Dérivés de la chloro-9 prednisolone. Ils répondent à la formule :Derivatives of 9-chloro prednisolone. They answer the formula:

FR7729740A 1976-10-04 1977-10-04 PREDNISOLONE 9-CHLORO DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING IT Granted FR2366313A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2645105A DE2645105C2 (en) 1976-10-04 1976-10-04 Derivatives of 9-chlorprednisolone, process for their preparation and pharmaceutical preparation containing them
DE19772742982 DE2742982C2 (en) 1977-09-21 1977-09-21 9-chlorprednisolone derivatives, process for their production and pharmaceutical preparation containing them

Publications (2)

Publication Number Publication Date
FR2366313A1 true FR2366313A1 (en) 1978-04-28
FR2366313B1 FR2366313B1 (en) 1980-02-01

Family

ID=25770978

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7729740A Granted FR2366313A1 (en) 1976-10-04 1977-10-04 PREDNISOLONE 9-CHLORO DERIVATIVES AND MEDICINAL PRODUCTS CONTAINING IT

Country Status (21)

Country Link
JP (1) JPS5359654A (en)
AT (1) AT358202B (en)
CH (4) CH630098A5 (en)
DK (1) DK438277A (en)
ES (1) ES462887A1 (en)
FI (1) FI58645C (en)
FR (1) FR2366313A1 (en)
GB (1) GB1594852A (en)
GR (1) GR73041B (en)
HU (1) HU179593B (en)
IE (1) IE45877B1 (en)
IL (1) IL53030A (en)
IT (1) IT1113623B (en)
LU (1) LU78223A1 (en)
NL (1) NL7710869A (en)
NO (1) NO148597C (en)
NZ (1) NZ185295A (en)
PL (1) PL110392B1 (en)
PT (1) PT67109B (en)
SE (1) SE431655B (en)
SU (2) SU743581A3 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0012271A1 (en) * 1978-12-11 1980-06-25 Schering Aktiengesellschaft Prednisone derivatives, process for their production and pharmaceutical preparations containing these compounds

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0374245A (en) * 1989-08-12 1991-03-28 Mk Seiko Co Ltd Car washing machine
US8513247B2 (en) 2010-03-26 2013-08-20 Galderma Laboratories, L.P. Methods and compositions for safe and effective treatment of erythema
CN103889417A (en) 2011-10-19 2014-06-25 高德美国际公司 Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors
CN106632561A (en) * 2016-12-16 2017-05-10 广州仁恒医药科技股份有限公司 Method for preparing difluprednate

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3152154A (en) * 1961-06-24 1964-10-06 Vismara Francesco Spa 17-monoesters of 17alpha, 21-dihydroxy steroids and process for the preparation thereof
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3152154A (en) * 1961-06-24 1964-10-06 Vismara Francesco Spa 17-monoesters of 17alpha, 21-dihydroxy steroids and process for the preparation thereof
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0012271A1 (en) * 1978-12-11 1980-06-25 Schering Aktiengesellschaft Prednisone derivatives, process for their production and pharmaceutical preparations containing these compounds

Also Published As

Publication number Publication date
GB1594852A (en) 1981-08-05
PL110392B1 (en) 1980-07-31
FI58645B (en) 1980-11-28
JPS6129960B2 (en) 1986-07-10
NZ185295A (en) 1980-04-28
NO773362L (en) 1978-04-05
IL53030A0 (en) 1977-11-30
PL201161A1 (en) 1979-01-29
CH632278A5 (en) 1982-09-30
NO148597C (en) 1983-11-09
CH632772A5 (en) 1982-10-29
HU179593B (en) 1982-11-29
JPS5359654A (en) 1978-05-29
PT67109A (en) 1977-11-01
FI58645C (en) 1981-03-10
IT1113623B (en) 1986-01-20
PT67109B (en) 1979-03-14
FR2366313B1 (en) 1980-02-01
SU743581A3 (en) 1980-06-25
IE45877B1 (en) 1982-12-15
IL53030A (en) 1982-11-30
DK438277A (en) 1978-04-05
LU78223A1 (en) 1978-02-01
SE7711039L (en) 1978-04-05
ES462887A1 (en) 1978-12-16
CH631997A5 (en) 1982-09-15
SU751327A3 (en) 1980-07-23
GR73041B (en) 1984-01-26
FI772922A (en) 1978-04-05
NO148597B (en) 1983-08-01
SE431655B (en) 1984-02-20
IE45877L (en) 1978-04-04
CH630098A5 (en) 1982-05-28
NL7710869A (en) 1978-04-06
ATA703577A (en) 1980-01-15
AT358202B (en) 1980-08-25

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Legal Events

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