FR2428649A1 - DIESTERS IN 17,21 OF HYDROCORTISONE AND MEDICINAL PRODUCTS CONTAINING SAME - Google Patents

DIESTERS IN 17,21 OF HYDROCORTISONE AND MEDICINAL PRODUCTS CONTAINING SAME

Info

Publication number
FR2428649A1
FR2428649A1 FR7915150A FR7915150A FR2428649A1 FR 2428649 A1 FR2428649 A1 FR 2428649A1 FR 7915150 A FR7915150 A FR 7915150A FR 7915150 A FR7915150 A FR 7915150A FR 2428649 A1 FR2428649 A1 FR 2428649A1
Authority
FR
France
Prior art keywords
hydrocortisone
diesters
products containing
containing same
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7915150A
Other languages
French (fr)
Other versions
FR2428649B1 (en
Inventor
Henning Sattler
Rudolf Petersen
Norbert Heinz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beiersdorf AG
Original Assignee
Beiersdorf AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf AG filed Critical Beiersdorf AG
Publication of FR2428649A1 publication Critical patent/FR2428649A1/en
Application granted granted Critical
Publication of FR2428649B1 publication Critical patent/FR2428649B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Abstract

Nouveaux diesters en 17,21 de l'hydrocortisone. Ils répondent à la formule :New diesters in 17,21 of hydrocortisone. They respond to the formula:

FR7915150A 1978-06-15 1979-06-13 DIESTERS IN 17,21 OF HYDROCORTISONE AND MEDICINAL PRODUCTS CONTAINING SAME Granted FR2428649A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2826257A DE2826257C3 (en) 1978-06-15 1978-06-15 Hydrocortisone-17,21-diester and process for their preparation, pharmaceuticals containing them and hydrocortisone -17-propionate as an intermediate

Publications (2)

Publication Number Publication Date
FR2428649A1 true FR2428649A1 (en) 1980-01-11
FR2428649B1 FR2428649B1 (en) 1982-06-11

Family

ID=6041871

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7915150A Granted FR2428649A1 (en) 1978-06-15 1979-06-13 DIESTERS IN 17,21 OF HYDROCORTISONE AND MEDICINAL PRODUCTS CONTAINING SAME

Country Status (11)

Country Link
JP (1) JPS5540662A (en)
AT (1) AT368757B (en)
AU (1) AU4760479A (en)
BE (1) BE877017A (en)
CA (1) CA1135253A (en)
CH (1) CH641476A5 (en)
DE (1) DE2826257C3 (en)
ES (1) ES481522A1 (en)
FR (1) FR2428649A1 (en)
GB (1) GB2023145A (en)
ZA (1) ZA792952B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6040439B2 (en) * 1978-03-29 1985-09-11 大正製薬株式会社 hydrocortisone derivatives
AT389447B (en) * 1983-01-27 1989-12-11 Taisho Pharmaceutical Co Ltd Process for the production of a topical steroid ointment
JPS59137408A (en) * 1983-01-27 1984-08-07 Taisho Pharmaceut Co Ltd Ointment
JPS59139315A (en) * 1983-01-31 1984-08-10 Taisho Pharmaceut Co Ltd Cream agent
DE3534742A1 (en) * 1985-09-28 1987-04-09 Beiersdorf Ag HYDROCORTISON'S MOST CONTAINING W / O CREAM
DE3534743A1 (en) * 1985-09-28 1987-04-02 Beiersdorf Ag HYDROCORTISON'S BEST CONTAINING O / W CREAM
DE4345186C2 (en) * 1993-12-27 1997-08-14 Galderma Sa Hydrocortisone 21-acetate-17-propionate containing W / O lotions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2144405A1 (en) * 1971-09-04 1973-03-08 Merck Patent Gmbh Saponification of pregnane series esters - using silica gel
SU427930A1 (en) * 1972-03-16 1974-05-15 А. А. Ахрем, И. С. Левина , Ю. А. Титов Институт органической химии Н. Д. Зелинского METHOD FOR OBTAINING DERIVATIVE CORTICOSTEROIDS
FR2421180A1 (en) * 1978-03-29 1979-10-26 Taisho Pharmaceutical Co Ltd HYDROCORTISONE 17-BUTYRATE 21-PROPIONATE AND ITS USE IN PARTICULAR AS AN ANTI-INFLAMMATORY AGENT

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2144405A1 (en) * 1971-09-04 1973-03-08 Merck Patent Gmbh Saponification of pregnane series esters - using silica gel
SU427930A1 (en) * 1972-03-16 1974-05-15 А. А. Ахрем, И. С. Левина , Ю. А. Титов Институт органической химии Н. Д. Зелинского METHOD FOR OBTAINING DERIVATIVE CORTICOSTEROIDS
FR2421180A1 (en) * 1978-03-29 1979-10-26 Taisho Pharmaceutical Co Ltd HYDROCORTISONE 17-BUTYRATE 21-PROPIONATE AND ITS USE IN PARTICULAR AS AN ANTI-INFLAMMATORY AGENT

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
CA1974 *
EXBK/77 *

Also Published As

Publication number Publication date
GB2023145A (en) 1979-12-28
AU4760479A (en) 1979-12-20
CH641476A5 (en) 1984-02-29
DE2826257A1 (en) 1979-12-20
CA1135253A (en) 1982-11-09
DE2826257C3 (en) 1980-12-04
AT368757B (en) 1982-11-10
ZA792952B (en) 1980-06-25
JPS5540662A (en) 1980-03-22
DE2826257B2 (en) 1980-03-06
ES481522A1 (en) 1980-01-16
FR2428649B1 (en) 1982-06-11
BE877017A (en) 1979-12-17
ATA422179A (en) 1982-03-15

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0426, 920616

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0426, 790613

CL Concession to grant licences
TP Transmission of property