PL201161A1 - METHOD OF MAKING NEW DERIVATIVES OF 9-CHLOROPREDISOLONE - Google Patents

METHOD OF MAKING NEW DERIVATIVES OF 9-CHLOROPREDISOLONE

Info

Publication number
PL201161A1
PL201161A1 PL20116177A PL20116177A PL201161A1 PL 201161 A1 PL201161 A1 PL 201161A1 PL 20116177 A PL20116177 A PL 20116177A PL 20116177 A PL20116177 A PL 20116177A PL 201161 A1 PL201161 A1 PL 201161A1
Authority
PL
Poland
Prior art keywords
chloropredisolone
new derivatives
making new
making
derivatives
Prior art date
Application number
PL20116177A
Other languages
Polish (pl)
Other versions
PL110392B1 (en
Inventor
Klaus Annen
Henry Laurent
Helmut Hofmeister
Rudolf Wiechert
Hans Wendt
Joachim F Kapp
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2645105A external-priority patent/DE2645105C2/en
Priority claimed from DE19772742982 external-priority patent/DE2742982C2/en
Application filed by Schering Ag filed Critical Schering Ag
Publication of PL201161A1 publication Critical patent/PL201161A1/en
Publication of PL110392B1 publication Critical patent/PL110392B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL1977201161A 1976-10-04 1977-09-30 Method of producing new derivatives of 9-chloroprednisolone PL110392B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2645105A DE2645105C2 (en) 1976-10-04 1976-10-04 Derivatives of 9-chlorprednisolone, process for their preparation and pharmaceutical preparation containing them
DE19772742982 DE2742982C2 (en) 1977-09-21 1977-09-21 9-chlorprednisolone derivatives, process for their production and pharmaceutical preparation containing them

Publications (2)

Publication Number Publication Date
PL201161A1 true PL201161A1 (en) 1979-01-29
PL110392B1 PL110392B1 (en) 1980-07-31

Family

ID=25770978

Family Applications (1)

Application Number Title Priority Date Filing Date
PL1977201161A PL110392B1 (en) 1976-10-04 1977-09-30 Method of producing new derivatives of 9-chloroprednisolone

Country Status (21)

Country Link
JP (1) JPS5359654A (en)
AT (1) AT358202B (en)
CH (4) CH630098A5 (en)
DK (1) DK438277A (en)
ES (1) ES462887A1 (en)
FI (1) FI58645C (en)
FR (1) FR2366313A1 (en)
GB (1) GB1594852A (en)
GR (1) GR73041B (en)
HU (1) HU179593B (en)
IE (1) IE45877B1 (en)
IL (1) IL53030A (en)
IT (1) IT1113623B (en)
LU (1) LU78223A1 (en)
NL (1) NL7710869A (en)
NO (1) NO148597C (en)
NZ (1) NZ185295A (en)
PL (1) PL110392B1 (en)
PT (1) PT67109B (en)
SE (1) SE431655B (en)
SU (2) SU743581A3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853785A1 (en) * 1978-12-11 1980-06-19 Schering Ag NEW PREDNISON DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS AND THE USE THEREOF
JPH0374245A (en) * 1989-08-12 1991-03-28 Mk Seiko Co Ltd car wash machine
ES2627405T3 (en) 2010-03-26 2017-07-28 Galderma Research & Development Compositions comprising brimonidine for the treatment of erythema
JP2014530846A (en) 2011-10-19 2014-11-20 ガルデルマ ソシエテ アノニム Method for reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors
CN106632561A (en) * 2016-12-16 2017-05-10 广州仁恒医药科技股份有限公司 Method for preparing difluprednate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH429716A (en) * 1961-06-24 1967-02-15 Vismara Francesco Spa Process for the preparation of 17a-acyloxy-21-hydroxy steroids
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride

Also Published As

Publication number Publication date
IL53030A0 (en) 1977-11-30
SE431655B (en) 1984-02-20
CH630098A5 (en) 1982-05-28
IL53030A (en) 1982-11-30
CH632772A5 (en) 1982-10-29
AT358202B (en) 1980-08-25
SE7711039L (en) 1978-04-05
SU751327A3 (en) 1980-07-23
PL110392B1 (en) 1980-07-31
NO773362L (en) 1978-04-05
IT1113623B (en) 1986-01-20
IE45877L (en) 1978-04-04
FR2366313A1 (en) 1978-04-28
FI772922A7 (en) 1978-04-05
PT67109B (en) 1979-03-14
NO148597C (en) 1983-11-09
SU743581A3 (en) 1980-06-25
JPS6129960B2 (en) 1986-07-10
CH632278A5 (en) 1982-09-30
GR73041B (en) 1984-01-26
NO148597B (en) 1983-08-01
HU179593B (en) 1982-11-29
ATA703577A (en) 1980-01-15
NL7710869A (en) 1978-04-06
NZ185295A (en) 1980-04-28
FI58645C (en) 1981-03-10
CH631997A5 (en) 1982-09-15
PT67109A (en) 1977-11-01
LU78223A1 (en) 1978-02-01
FR2366313B1 (en) 1980-02-01
DK438277A (en) 1978-04-05
FI58645B (en) 1980-11-28
IE45877B1 (en) 1982-12-15
GB1594852A (en) 1981-08-05
JPS5359654A (en) 1978-05-29
ES462887A1 (en) 1978-12-16

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