IE45877L - Delta-1,4-pregnadienes - Google Patents

Delta-1,4-pregnadienes

Info

Publication number
IE45877L
IE45877L IE772011A IE201177A IE45877L IE 45877 L IE45877 L IE 45877L IE 772011 A IE772011 A IE 772011A IE 201177 A IE201177 A IE 201177A IE 45877 L IE45877 L IE 45877L
Authority
IE
Ireland
Prior art keywords
pregnadienes
delta
prednisolone
chloro
derived
Prior art date
Application number
IE772011A
Other versions
IE45877B1 (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2645105A external-priority patent/DE2645105C2/en
Priority claimed from DE19772742982 external-priority patent/DE2742982C2/en
Application filed by Schering Ag filed Critical Schering Ag
Publication of IE45877L publication Critical patent/IE45877L/en
Publication of IE45877B1 publication Critical patent/IE45877B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Derived from the chloro-9 prednisolone. They correspond to the formula: [FR2366313A1]
IE2011/77A 1976-10-04 1977-10-03 New derivatives of 9-chloroprednisolone IE45877B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2645105A DE2645105C2 (en) 1976-10-04 1976-10-04 Derivatives of 9-chlorprednisolone, process for their preparation and pharmaceutical preparation containing them
DE19772742982 DE2742982C2 (en) 1977-09-21 1977-09-21 9-chlorprednisolone derivatives, process for their production and pharmaceutical preparation containing them

Publications (2)

Publication Number Publication Date
IE45877L true IE45877L (en) 1978-04-04
IE45877B1 IE45877B1 (en) 1982-12-15

Family

ID=25770978

Family Applications (1)

Application Number Title Priority Date Filing Date
IE2011/77A IE45877B1 (en) 1976-10-04 1977-10-03 New derivatives of 9-chloroprednisolone

Country Status (21)

Country Link
JP (1) JPS5359654A (en)
AT (1) AT358202B (en)
CH (4) CH630098A5 (en)
DK (1) DK438277A (en)
ES (1) ES462887A1 (en)
FI (1) FI58645C (en)
FR (1) FR2366313A1 (en)
GB (1) GB1594852A (en)
GR (1) GR73041B (en)
HU (1) HU179593B (en)
IE (1) IE45877B1 (en)
IL (1) IL53030A (en)
IT (1) IT1113623B (en)
LU (1) LU78223A1 (en)
NL (1) NL7710869A (en)
NO (1) NO148597C (en)
NZ (1) NZ185295A (en)
PL (1) PL110392B1 (en)
PT (1) PT67109B (en)
SE (1) SE431655B (en)
SU (2) SU743581A3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853785A1 (en) * 1978-12-11 1980-06-19 Schering Ag NEW PREDNISON DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS AND THE USE THEREOF
JPH0374245A (en) * 1989-08-12 1991-03-28 Mk Seiko Co Ltd Car washing machine
AU2011231543B2 (en) 2010-03-26 2015-01-15 Galderma Research & Development Improved methods and compositions for safe and effective treatment of erythema
US9744168B2 (en) 2011-10-19 2017-08-29 Galderma Laboratories, Inc. Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors
CN106632561A (en) * 2016-12-16 2017-05-10 广州仁恒医药科技股份有限公司 Method for preparing difluprednate

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1195748B (en) * 1961-06-24 1965-07-01 Vismara Francesco Spa Process for the preparation of 1'-substituted 17alpha, 21- (1'-alkoxy) -methylenedioxysteriodes
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride

Also Published As

Publication number Publication date
ATA703577A (en) 1980-01-15
FI58645B (en) 1980-11-28
FI772922A (en) 1978-04-05
FI58645C (en) 1981-03-10
HU179593B (en) 1982-11-29
NO148597C (en) 1983-11-09
NO773362L (en) 1978-04-05
PT67109A (en) 1977-11-01
GR73041B (en) 1984-01-26
SE431655B (en) 1984-02-20
NZ185295A (en) 1980-04-28
CH630098A5 (en) 1982-05-28
PL110392B1 (en) 1980-07-31
SU743581A3 (en) 1980-06-25
AT358202B (en) 1980-08-25
PT67109B (en) 1979-03-14
IL53030A (en) 1982-11-30
NL7710869A (en) 1978-04-06
GB1594852A (en) 1981-08-05
SU751327A3 (en) 1980-07-23
IE45877B1 (en) 1982-12-15
DK438277A (en) 1978-04-05
PL201161A1 (en) 1979-01-29
IT1113623B (en) 1986-01-20
FR2366313A1 (en) 1978-04-28
FR2366313B1 (en) 1980-02-01
ES462887A1 (en) 1978-12-16
LU78223A1 (en) 1978-02-01
CH632278A5 (en) 1982-09-30
SE7711039L (en) 1978-04-05
CH632772A5 (en) 1982-10-29
CH631997A5 (en) 1982-09-15
JPS6129960B2 (en) 1986-07-10
NO148597B (en) 1983-08-01
IL53030A0 (en) 1977-11-30
JPS5359654A (en) 1978-05-29

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