JPS5337652A - Production of 9 alphaa chloroo11 betaafluoroo steroid and pharmaceutical composition - Google Patents

Production of 9 alphaa chloroo11 betaafluoroo steroid and pharmaceutical composition

Info

Publication number
JPS5337652A
JPS5337652A JP11060977A JP11060977A JPS5337652A JP S5337652 A JPS5337652 A JP S5337652A JP 11060977 A JP11060977 A JP 11060977A JP 11060977 A JP11060977 A JP 11060977A JP S5337652 A JPS5337652 A JP S5337652A
Authority
JP
Japan
Prior art keywords
chloroo11
betaafluoroo
alphaa
steroid
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11060977A
Other languages
Japanese (ja)
Inventor
Biora Mishieru
Karufuoda Yarosurafu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of JPS5337652A publication Critical patent/JPS5337652A/en
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C07J7/001Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
    • C07J7/0015Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
    • C07J7/002Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa not substituted in position 16

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP11060977A 1976-09-16 1977-09-16 Production of 9 alphaa chloroo11 betaafluoroo steroid and pharmaceutical composition Pending JPS5337652A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU75809A LU75809A1 (en) 1976-09-16 1976-09-16

Publications (1)

Publication Number Publication Date
JPS5337652A true JPS5337652A (en) 1978-04-06

Family

ID=19728351

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11060977A Pending JPS5337652A (en) 1976-09-16 1977-09-16 Production of 9 alphaa chloroo11 betaafluoroo steroid and pharmaceutical composition

Country Status (13)

Country Link
JP (1) JPS5337652A (en)
AT (1) AT356303B (en)
AU (1) AU514425B2 (en)
BE (1) BE858709A (en)
CA (1) CA1105003A (en)
DE (1) DE2741067A1 (en)
DK (1) DK410077A (en)
FR (1) FR2364928A1 (en)
GB (1) GB1584826A (en)
LU (1) LU75809A1 (en)
NL (1) NL7710086A (en)
SE (1) SE7710337L (en)
ZA (1) ZA775537B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0029151B1 (en) * 1979-11-16 1985-09-25 STEROSYNT Ltd. 6-alpha-fluoro-9-alpha-chloro-prednisolone-17,21 diesters, pharmaceutical compositions containing them and intermediates
IT1209140B (en) * 1979-11-16 1989-07-10 Prochem Ets 6 ALFA-FLUORO-PREDNISOLONE 17,21-DIESTERI.

Also Published As

Publication number Publication date
FR2364928A1 (en) 1978-04-14
DE2741067A1 (en) 1978-03-23
SE7710337L (en) 1978-03-17
DK410077A (en) 1978-03-17
GB1584826A (en) 1981-02-18
LU75809A1 (en) 1978-05-12
BE858709A (en) 1978-03-15
FR2364928B1 (en) 1981-03-06
ZA775537B (en) 1978-07-26
ATA663077A (en) 1979-09-15
AU514425B2 (en) 1981-02-12
CA1105003A (en) 1981-07-14
NL7710086A (en) 1978-03-20
AU2884877A (en) 1979-03-22
AT356303B (en) 1980-04-25

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