DK438277A - Fremgangsmaade til fremstilling af 9-chlorprednisoloner - Google Patents

Fremgangsmaade til fremstilling af 9-chlorprednisoloner

Info

Publication number
DK438277A
DK438277A DK438277A DK438277A DK438277A DK 438277 A DK438277 A DK 438277A DK 438277 A DK438277 A DK 438277A DK 438277 A DK438277 A DK 438277A DK 438277 A DK438277 A DK 438277A
Authority
DK
Denmark
Prior art keywords
predisanolons
chloro
procedure
preparation
chloro predisanolons
Prior art date
Application number
DK438277A
Other languages
Danish (da)
English (en)
Inventor
K Annen
H Laurent
H Hofmeister
R Wiechert
H Wendt
J F Kapp
Original Assignee
Scdherning Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2645105A external-priority patent/DE2645105C2/de
Priority claimed from DE19772742982 external-priority patent/DE2742982C2/de
Application filed by Scdherning Ag filed Critical Scdherning Ag
Publication of DK438277A publication Critical patent/DK438277A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0053Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/008Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
    • C07J7/0085Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK438277A 1976-10-04 1977-10-04 Fremgangsmaade til fremstilling af 9-chlorprednisoloner DK438277A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2645105A DE2645105C2 (de) 1976-10-04 1976-10-04 Derivate des 9-Chlorprednisolons, Verfahren zu ihrer Herstellung und diese enthaltendes pharmazeutisches Präparat
DE19772742982 DE2742982C2 (de) 1977-09-21 1977-09-21 9-Chlorprednisolon-Derivate, Verfahren zu deren Herstellung und diese enthaltendes pharmazeutisches Präparat

Publications (1)

Publication Number Publication Date
DK438277A true DK438277A (da) 1978-04-05

Family

ID=25770978

Family Applications (1)

Application Number Title Priority Date Filing Date
DK438277A DK438277A (da) 1976-10-04 1977-10-04 Fremgangsmaade til fremstilling af 9-chlorprednisoloner

Country Status (21)

Country Link
JP (1) JPS5359654A (de)
AT (1) AT358202B (de)
CH (4) CH630098A5 (de)
DK (1) DK438277A (de)
ES (1) ES462887A1 (de)
FI (1) FI58645C (de)
FR (1) FR2366313A1 (de)
GB (1) GB1594852A (de)
GR (1) GR73041B (de)
HU (1) HU179593B (de)
IE (1) IE45877B1 (de)
IL (1) IL53030A (de)
IT (1) IT1113623B (de)
LU (1) LU78223A1 (de)
NL (1) NL7710869A (de)
NO (1) NO148597C (de)
NZ (1) NZ185295A (de)
PL (1) PL110392B1 (de)
PT (1) PT67109B (de)
SE (1) SE431655B (de)
SU (2) SU743581A3 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2853785A1 (de) * 1978-12-11 1980-06-19 Schering Ag Neue prednison-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende pharmazeutische praeparate und deren verwendung
JPH0374245A (ja) * 1989-08-12 1991-03-28 Mk Seiko Co Ltd 洗車機
BR112012024289A2 (pt) 2010-03-26 2017-07-18 Galderma Res & Dev "método para fornecer um tratamento seguro e efetivo do eritema e composição de gel tópica"
CA2850273A1 (en) 2011-10-19 2013-04-25 Galderma S.A. Method of reducing facial flushing associated with systemic use of phosphodiesterase type 5 inhibitors
CN106632561A (zh) * 2016-12-16 2017-05-10 广州仁恒医药科技股份有限公司 一种二氟泼尼酯的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH429716A (de) * 1961-06-24 1967-02-15 Vismara Francesco Spa Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden
DE2055221A1 (en) * 1970-11-10 1972-05-18 Laboratorio Chimico Farmaceutico Dr. P. Blasina S.R.L., Mailand (Italien) 17-acyloxy-3-keto-pregn-4-enes prepn - by acylating 17-hydroxy steroids in presence ofstannic chloride

Also Published As

Publication number Publication date
PT67109B (de) 1979-03-14
IT1113623B (it) 1986-01-20
PT67109A (de) 1977-11-01
IE45877L (en) 1978-04-04
NL7710869A (nl) 1978-04-06
GB1594852A (en) 1981-08-05
CH632278A5 (en) 1982-09-30
NO148597C (no) 1983-11-09
SU751327A3 (ru) 1980-07-23
CH632772A5 (en) 1982-10-29
JPS6129960B2 (de) 1986-07-10
GR73041B (de) 1984-01-26
IE45877B1 (en) 1982-12-15
ES462887A1 (es) 1978-12-16
ATA703577A (de) 1980-01-15
FR2366313B1 (de) 1980-02-01
LU78223A1 (de) 1978-02-01
IL53030A (en) 1982-11-30
PL201161A1 (pl) 1979-01-29
CH630098A5 (en) 1982-05-28
NO148597B (no) 1983-08-01
FI58645C (fi) 1981-03-10
SE431655B (sv) 1984-02-20
HU179593B (en) 1982-11-29
FR2366313A1 (fr) 1978-04-28
AT358202B (de) 1980-08-25
NO773362L (no) 1978-04-05
FI772922A (fi) 1978-04-05
IL53030A0 (en) 1977-11-30
SE7711039L (sv) 1978-04-05
SU743581A3 (ru) 1980-06-25
JPS5359654A (en) 1978-05-29
CH631997A5 (en) 1982-09-15
FI58645B (fi) 1980-11-28
PL110392B1 (en) 1980-07-31
NZ185295A (en) 1980-04-28

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment