CH429716A - Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden - Google Patents

Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden

Info

Publication number
CH429716A
CH429716A CH666862A CH666862A CH429716A CH 429716 A CH429716 A CH 429716A CH 666862 A CH666862 A CH 666862A CH 666862 A CH666862 A CH 666862A CH 429716 A CH429716 A CH 429716A
Authority
CH
Switzerland
Prior art keywords
acyloxy
preparation
hydroxy steroids
steroids
hydroxy
Prior art date
Application number
CH666862A
Other languages
English (en)
Inventor
Alberto Prof Ercoli
Rinaldo Dr Gardi
Original Assignee
Vismara Francesco Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DEV21321A external-priority patent/DE1173897B/de
Application filed by Vismara Francesco Spa filed Critical Vismara Francesco Spa
Publication of CH429716A publication Critical patent/CH429716A/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
CH666862A 1961-06-24 1962-06-01 Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden CH429716A (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1165961 1961-06-24
DEV21321A DE1173897B (de) 1961-06-24 1961-09-18 Verfahren zur Herstellung von cyclischen 17ª‡, 21-Orthoameisensaeureestern von ?-3-Ketosteroiden

Publications (1)

Publication Number Publication Date
CH429716A true CH429716A (de) 1967-02-15

Family

ID=26001548

Family Applications (1)

Application Number Title Priority Date Filing Date
CH666862A CH429716A (de) 1961-06-24 1962-06-01 Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden

Country Status (4)

Country Link
US (1) US3152154A (de)
CH (1) CH429716A (de)
DE (1) DE1195748B (de)
GB (2) GB996080A (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1047518A (en) * 1963-06-11 1966-11-02 Glaxo Lab Ltd 17ª‡-monoesters of 11,17,21-trihydroxy steroid compounds
GB1070751A (en) * 1964-01-28 1967-06-01 Glaxo Lab Ltd 17-esters of 17-hydroxy-21-desoxy-steroids
US3499081A (en) * 1966-12-21 1970-03-03 Squibb & Sons Inc 9-chloroprogestational agents
US3502700A (en) * 1967-01-19 1970-03-24 Squibb & Sons Inc 17-esters of 9alpha,21-dihalo-11beta,17alpha-dihydroxyprogesterones
FR2029415A1 (en) * 1969-01-30 1970-10-23 Ciba Geigy Ag 2-chloro-6alpha 9alpha-difluoro-16alpha-methylpregna-1
IT1033042B (it) * 1970-03-14 1979-07-10 Luso Farmaco Inst Desametazone 17 valerato e processi per la sua preparazione
US3694471A (en) * 1970-06-08 1972-09-26 Warner Lambert Pharmaceutical 17-valerate ester of 6{60 ,9{60 -difluorohydrocortisone, its compositions and use as an anti-inflammatory agent
US3857941A (en) * 1970-06-22 1974-12-31 Warner Lambert Co Pharmaceutical compositions and use of prednisolone 17-benzoate
US3789121A (en) * 1971-11-26 1974-01-29 Warner Lambert Co 17{60 ,21-orthobutyrates of 6{60 , 9{60 -difluoro-hydrocortisone and 6{60 , 9{60 -difluoroprednisolone, compositions containing same and the use thereof as anti-inflammatory agents
US4036831A (en) * 1975-10-28 1977-07-19 Steroid Development Company Establishment Trimethyl siloxane steroid intermediates
NZ185295A (en) * 1976-10-04 1980-04-28 Schering Ag 9-chloroprednisolone derivatives and pharmaceutical compositions
DE2735110A1 (de) * 1977-08-04 1979-02-15 Hoechst Ag Corticoid-17-alkylcarbonate und verfahren zu ihrer herstellung
JPS6040439B2 (ja) * 1978-03-29 1985-09-11 大正製薬株式会社 ヒドロコルチゾン誘導体
DE3068965D1 (en) * 1979-11-16 1984-09-20 Sterosynt Ltd 6-alpha-fluoro-16-methyl-prednisolone-17,21 diesters and pharmaceutical compositions containing them
US4318853A (en) * 1980-01-31 1982-03-09 The Upjohn Company 9β,11β-Epoxy-5β-corticoids
US4353985A (en) * 1980-07-14 1982-10-12 Schering Aktiengesellschaft Process for the preparation of 11 β-hydroxy steroids
DE3227312A1 (de) * 1982-07-19 1984-01-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
DE3401680A1 (de) * 1984-01-16 1985-07-18 Schering AG, 1000 Berlin und 4709 Bergkamen 6(alpha),16ss-dimethylkortikoide
ITMI20011762A1 (it) * 2001-08-10 2003-02-10 Cosmo Spa Esteri di 17alfa,21-diidrossipregnene, loro uso come agenti anti-androgenetici e procedimenti per la loro preparazione
ITMI20071616A1 (it) 2007-08-03 2009-02-04 Cosmo Spa Processo enzimatico per l'ottenimento di 17-alfa monoesteri del cortexolone e/o suoi 9,11-deidroderivati.
EP3006453A1 (de) 2014-10-08 2016-04-13 Cosmo Technologies Ltd. 17alpha-Monoester und 17alpha,21-Diester von Cortodoxon zur Verwendung bei der Behandlung von Tumoren
EP3108879A1 (de) 2015-06-25 2016-12-28 Cassiopea S.p.A. Hochkonzentrierte formulierung
DE112021004932T5 (de) 2020-10-19 2023-08-10 Industriale Chimica S.R.L. Verfahren zur herstellung von 21-(acetyloxy)-17-(1-oxopropoxy)-pregn-4-en-3,20-dion
IT202100008429A1 (it) 2021-04-06 2022-10-06 Farmabios Spa Processo per la preparazione di cortexolone 17α-propionato e sua nuova forma cristallina idrata
WO2023088308A1 (zh) * 2021-11-16 2023-05-25 石家庄迪斯凯威医药科技有限公司 一种具有抗耐药性的抗菌化合物
CN115466301A (zh) * 2022-08-29 2022-12-13 扬州奥锐特药业有限公司 一种甾体化合物，其晶型a及它们的制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2932656A (en) * 1957-06-19 1960-04-12 Merck & Co Inc Production of delta1, 4-3, 20-diketopregnadienes from the corresponding semicarbazones
US2971886A (en) * 1957-11-27 1961-02-14 Upjohn Co 1-dehydro-17-hydroxyprogesterone acylates and therapeutic composition thereof
US2864839A (en) * 1958-07-25 1958-12-16 Olin Mathieson delta4, 7, 9(11)-pregnatriene-17alpha, 21-diol-3, 20-dione and process therefor

Also Published As

Publication number Publication date
GB963829A (en) 1964-07-15
GB996080A (en) 1965-06-23
DE1195748B (de) 1965-07-01
US3152154A (en) 1964-10-06

Similar Documents

Publication Publication Date Title
CH429716A (de) Verfahren zur Herstellung von 17a-Acyloxy-21-hydroxy-Steroiden
CH420067A (de) Verfahren zur Herstellung von ortho-Alkylphenolen
CH460776A (de) Verfahren zur Herstellung von Triazolidinen
CH425813A (de) Verfahren zur Herstellung von Trialkalinitrilotriacetat
AT255031B (de) Verfahren zur Herstellung von 1-Glykosyl-6-azauracilen
CH420186A (de) Verfahren zur Herstellung von 2-Amino-benzophenonen
CH420185A (de) Verfahren zur Herstellung von 5-Mononucleotiden
AT239438B (de) Verfahren zur Herstellung von α-Aminobenzylpenicillin
AT241687B (de) Verfahren zur Herstellung von α-Aminobenzylpenicillin
CH421120A (de) Verfahren zur Herstellung von Sulfapyrimidinen
CH419146A (de) Verfahren zur Herstellung von 3-Phenyl-7-pyrazolyl-cumarinen
CH413836A (de) Verfahren zur Herstellung von Distilbazolen
CH420135A (de) Verfahren zur Herstellung von 16-Alkylpregnenen
CH427793A (de) Verfahren zur Herstellung von Benzolsulfonylsemicarbaziden
CH439291A (de) Verfahren zur Herstellung von Thiazolosteroiden
CH401026A (de) Verfahren zur Herstellung von B-Ketoamiden
CH446392A (de) Verfahren zur Herstellung von Diphenylalkanolaminen
CH454131A (de) Verfahren zur Herstellung von 19-Norsteroiden
CH402854A (de) Verfahren zur Herstellung von 6a-Difluormethylsteroiden
CH422770A (de) Verfahren zur Herstellung von 15-Methylsteroiden
CH410932A (de) Verfahren zur Herstellung von 7a-Alkylthio-steroiden
CH401949A (de) Verfahren zur Herstellung von 1-Alkyl-1-alkoxy-3-arylharnstoff
CH437270A (de) Verfahren zur Herstellung von 10-Formylsteroiden
CH456588A (de) Verfahren zur Herstellung von 12-Alkylaminosteroiden
CH420129A (de) Verfahren zur Herstellung von 10-Formylsteroiden