SU498908A3 - Способ получени производных пиримидинона - Google Patents

Способ получени производных пиримидинона

Info

Publication number
SU498908A3
SU498908A3 SU1839308A SU1839308A SU498908A3 SU 498908 A3 SU498908 A3 SU 498908A3 SU 1839308 A SU1839308 A SU 1839308A SU 1839308 A SU1839308 A SU 1839308A SU 498908 A3 SU498908 A3 SU 498908A3
Authority
SU
USSR - Soviet Union
Prior art keywords
producing
methyl
pyrimidinone derivatives
derivatives
ethanol
Prior art date
Application number
SU1839308A
Other languages
English (en)
Russian (ru)
Inventor
Эндрю Липински Христофер
Джеррит Стам Джон
Джорж Деанджелис Джеральд
Юрген Эрнест Гесс Ганс
Original Assignee
Пфайзер Инк (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Инк (Фирма) filed Critical Пфайзер Инк (Фирма)
Application granted granted Critical
Publication of SU498908A3 publication Critical patent/SU498908A3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
SU1839308A 1971-10-29 1972-10-13 Способ получени производных пиримидинона SU498908A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (1)

Publication Number Publication Date
SU498908A3 true SU498908A3 (ru) 1976-01-05

Family

ID=22715935

Family Applications (2)

Application Number Title Priority Date Filing Date
SU1839308A SU498908A3 (ru) 1971-10-29 1972-10-13 Способ получени производных пиримидинона
SU2008490A SU505362A3 (ru) 1971-10-29 1974-03-26 Способ получени оксипиримидинов

Family Applications After (1)

Application Number Title Priority Date Filing Date
SU2008490A SU505362A3 (ru) 1971-10-29 1974-03-26 Способ получени оксипиримидинов

Country Status (25)

Country Link
JP (2) JPS5337870B2 (uk)
AR (2) AR198798A1 (uk)
AT (2) AT321308B (uk)
AU (1) AU467600B2 (uk)
BE (1) BE790125A (uk)
CA (1) CA980778A (uk)
CH (2) CH555832A (uk)
DE (3) DE2248741C3 (uk)
DK (1) DK131465B (uk)
EG (1) EG11013A (uk)
ES (2) ES407730A1 (uk)
FI (1) FI55503C (uk)
FR (1) FR2157865B1 (uk)
GB (2) GB1377308A (uk)
IE (1) IE37043B1 (uk)
IL (2) IL40458A (uk)
LU (1) LU66304A1 (uk)
NL (1) NL166470C (uk)
NO (1) NO136574C (uk)
PH (2) PH10129A (uk)
PL (2) PL89852B1 (uk)
SE (2) SE393376B (uk)
SU (2) SU498908A3 (uk)
YU (2) YU35125B (uk)
ZA (1) ZA727362B (uk)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (uk) * 1979-04-17 1980-11-01
JPS5752409Y2 (uk) * 1979-11-05 1982-11-15
DE3222914A1 (de) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg Substituierte 5-phenylthio-6-amino-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPH0655686B2 (ja) * 1988-08-30 1994-07-27 宇部興産株式会社 ｐ−ブロモフェノキシアセトアルデヒドジアルキルアセタール類の製造方法
KR101452518B1 (ko) 2005-08-22 2014-10-21 멜리어 파마슈티칼스 아이, 인코포레이티드 Ｌｙｎ 키나제 활성의 조절 및 관련된 장애의 치료를 위한방법 및 제제
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
WO2011150300A1 (en) 2010-05-28 2011-12-01 Melior Pharmaceuticals I, Inc. Prevention of pancreatic beta cell degeneration
CN110785170B (zh) 2017-04-10 2023-03-28 梅里奥尔医药I公司 脂肪细胞的治疗

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951432A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
PL84634B1 (uk) 1976-04-30
DK131465B (da) 1975-07-21
DE2264374C3 (de) 1981-07-23
IL40458A (en) 1976-05-31
FI55503B (fi) 1979-04-30
DE2264374B2 (de) 1980-08-07
DE2248741B2 (de) 1974-11-14
NL166470C (nl) 1981-08-17
ZA727362B (en) 1973-11-28
SE7505279L (sv) 1975-05-06
NO136574C (no) 1977-09-28
DE2248741C3 (de) 1975-06-26
CH555832A (fr) 1974-11-15
JPS5422995B2 (uk) 1979-08-10
FI55503C (fi) 1979-08-10
LU66304A1 (uk) 1973-05-03
IL48790A (en) 1976-05-31
SE397090B (sv) 1977-10-17
AU467600B2 (en) 1975-12-04
JPS5337870B2 (uk) 1978-10-12
NL7213959A (uk) 1973-05-02
DK131465C (uk) 1975-12-08
PH10129A (en) 1976-09-02
SU505362A3 (ru) 1976-02-28
DE2264657A1 (de) 1974-06-20
YU36295B (en) 1982-06-18
FR2157865A1 (uk) 1973-06-08
DE2248741A1 (de) 1973-05-03
IE37043L (en) 1973-04-29
BE790125A (fr) 1973-04-16
PH11594A (en) 1978-03-31
IE37043B1 (en) 1977-04-27
JPS53116386A (en) 1978-10-11
AT321308B (de) 1975-03-25
SE393376B (sv) 1977-05-09
YU35125B (en) 1980-09-25
AR198798A1 (es) 1974-07-24
DE2264657C2 (de) 1982-09-16
AT320656B (de) 1975-02-25
IL40458A0 (en) 1972-11-28
AR196263A1 (es) 1973-12-10
CH549579A (fr) 1974-05-31
NO136574B (uk) 1977-06-20
YU255172A (en) 1980-03-15
DE2264374A1 (de) 1973-05-24
AU4722872A (en) 1974-04-04
PL89852B1 (uk) 1976-12-31
FR2157865B1 (uk) 1975-10-31
ES436624A1 (es) 1977-02-01
GB1377308A (en) 1974-12-11
CA980778A (en) 1975-12-30
YU99179A (en) 1981-08-31
EG11013A (en) 1976-11-30
NL166470B (nl) 1981-03-16
ES407730A1 (es) 1976-01-16
IL48790A0 (en) 1976-03-31
GB1377720A (en) 1974-12-18
JPS4852780A (uk) 1973-07-24

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