BE790125A - Nouvelles pyrimidinones et nouvelles hydroxypyrimidines - Google Patents

Nouvelles pyrimidinones et nouvelles hydroxypyrimidines

Info

Publication number
BE790125A
BE790125A BE790125DA BE790125A BE 790125 A BE790125 A BE 790125A BE 790125D A BE790125D A BE 790125DA BE 790125 A BE790125 A BE 790125A
Authority
BE
Belgium
Prior art keywords
new
hydroxypyrimidines
pyrimidinones
new pyrimidinones
new hydroxypyrimidines
Prior art date
Application number
Other languages
English (en)
Inventor
Lipinski
J G Stam
G G Deangelis
H-J E Hess
C A Lipinski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Publication of BE790125A publication Critical patent/BE790125A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BE790125D 1971-10-29 Nouvelles pyrimidinones et nouvelles hydroxypyrimidines BE790125A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (1)

Publication Number Publication Date
BE790125A true BE790125A (fr) 1973-04-16

Family

ID=22715935

Family Applications (1)

Application Number Title Priority Date Filing Date
BE790125D BE790125A (fr) 1971-10-29 Nouvelles pyrimidinones et nouvelles hydroxypyrimidines

Country Status (25)

Country Link
JP (2) JPS5337870B2 (fr)
AR (2) AR198798A1 (fr)
AT (2) AT320656B (fr)
AU (1) AU467600B2 (fr)
BE (1) BE790125A (fr)
CA (1) CA980778A (fr)
CH (2) CH549579A (fr)
DE (3) DE2264657C2 (fr)
DK (1) DK131465B (fr)
EG (1) EG11013A (fr)
ES (2) ES407730A1 (fr)
FI (1) FI55503C (fr)
FR (1) FR2157865B1 (fr)
GB (2) GB1377308A (fr)
IE (1) IE37043B1 (fr)
IL (2) IL40458A (fr)
LU (1) LU66304A1 (fr)
NL (1) NL166470C (fr)
NO (1) NO136574C (fr)
PH (2) PH10129A (fr)
PL (2) PL84634B1 (fr)
SE (2) SE393376B (fr)
SU (2) SU498908A3 (fr)
YU (2) YU35125B (fr)
ZA (1) ZA727362B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (fr) * 1979-04-17 1980-11-01
JPS5752409Y2 (fr) * 1979-11-05 1982-11-15
DE3222914A1 (de) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg Substituierte 5-phenylthio-6-amino-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPH0655686B2 (ja) * 1988-08-30 1994-07-27 宇部興産株式会社 ｐ−ブロモフェノキシアセトアルデヒドジアルキルアセタール類の製造方法
US7776870B2 (en) 2005-08-22 2010-08-17 Melior Pharmaceuticals I, Inc. Methods for modulating Lyn kinase activity and treating related disorders
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
WO2011150300A1 (fr) 2010-05-28 2011-12-01 Melior Pharmaceuticals I, Inc. Prévention de la dégénérescence des cellules pancréatiques bêta
BR112019021140A2 (pt) 2017-04-10 2020-05-19 Univ Louisiana State composição, método para reduzir os níveis de glicose no sangue, ganho de peso ou níveis de depósito de gordura, ou tratamento, método de indução do bege de adipócitos ou prevenção da degeneração das células beta do pâncreas, e, ativador de lyn cinase e agonista de trpm8 para uso na redução dos níveis de glicose no sangue, ganho de peso ou níveis de depósito de gordura, ou tratamento.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951431A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
IL48790A0 (en) 1976-03-31
CH555832A (fr) 1974-11-15
AR198798A1 (es) 1974-07-24
NL7213959A (fr) 1973-05-02
PH11594A (en) 1978-03-31
ES407730A1 (es) 1976-01-16
YU36295B (en) 1982-06-18
JPS4852780A (fr) 1973-07-24
SE397090B (sv) 1977-10-17
FI55503B (fi) 1979-04-30
YU99179A (en) 1981-08-31
FI55503C (fi) 1979-08-10
AR196263A1 (es) 1973-12-10
FR2157865A1 (fr) 1973-06-08
CH549579A (fr) 1974-05-31
DK131465B (da) 1975-07-21
IE37043L (en) 1973-04-29
DE2264374A1 (de) 1973-05-24
SE393376B (sv) 1977-05-09
JPS5337870B2 (fr) 1978-10-12
NO136574C (no) 1977-09-28
YU35125B (en) 1980-09-25
ZA727362B (en) 1973-11-28
AT321308B (de) 1975-03-25
FR2157865B1 (fr) 1975-10-31
AU4722872A (en) 1974-04-04
PH10129A (en) 1976-09-02
JPS5422995B2 (fr) 1979-08-10
YU255172A (en) 1980-03-15
DK131465C (fr) 1975-12-08
SE7505279L (sv) 1975-05-06
EG11013A (en) 1976-11-30
NL166470B (nl) 1981-03-16
SU498908A3 (ru) 1976-01-05
IE37043B1 (en) 1977-04-27
JPS53116386A (en) 1978-10-11
DE2248741A1 (de) 1973-05-03
DE2248741C3 (de) 1975-06-26
ES436624A1 (es) 1977-02-01
LU66304A1 (fr) 1973-05-03
DE2264374C3 (de) 1981-07-23
AT320656B (de) 1975-02-25
IL40458A (en) 1976-05-31
DE2264657A1 (de) 1974-06-20
NL166470C (nl) 1981-08-17
CA980778A (en) 1975-12-30
NO136574B (fr) 1977-06-20
GB1377308A (en) 1974-12-11
DE2264657C2 (de) 1982-09-16
GB1377720A (en) 1974-12-18
IL40458A0 (en) 1972-11-28
IL48790A (en) 1976-05-31
DE2248741B2 (de) 1974-11-14
DE2264374B2 (de) 1980-08-07
PL89852B1 (fr) 1976-12-31
PL84634B1 (fr) 1976-04-30
SU505362A3 (ru) 1976-02-28
AU467600B2 (en) 1975-12-04

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: PFIZER INC

Effective date: 19841016