DK131465B - Analogifremgangsmåde til fremstilling af pyrimidinon-forbindelser. - Google Patents

Analogifremgangsmåde til fremstilling af pyrimidinon-forbindelser.

Info

Publication number
DK131465B
DK131465B DK510072AA DK510072A DK131465B DK 131465 B DK131465 B DK 131465B DK 510072A A DK510072A A DK 510072AA DK 510072 A DK510072 A DK 510072A DK 131465 B DK131465 B DK 131465B
Authority
DK
Denmark
Prior art keywords
preparation
analogous process
pyrimidinone compounds
pyrimidinone
compounds
Prior art date
Application number
DK510072AA
Other languages
Danish (da)
English (en)
Other versions
DK131465C (fr
Inventor
C A Lipinski
J G Stam
G G Deangelis
H-J E Hess
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Priority to DK294974A priority Critical patent/DK134016B/da
Publication of DK131465B publication Critical patent/DK131465B/da
Application granted granted Critical
Publication of DK131465C publication Critical patent/DK131465C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK510072AA 1971-10-29 1972-10-16 Analogifremgangsmåde til fremstilling af pyrimidinon-forbindelser. DK131465B (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK294974A DK134016B (da) 1971-10-29 1974-05-31 Analogifremgangsmåde til fremstilling af hydroxypyrimidin-forbindelser.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (2)

Publication Number Publication Date
DK131465B true DK131465B (da) 1975-07-21
DK131465C DK131465C (fr) 1975-12-08

Family

ID=22715935

Family Applications (1)

Application Number Title Priority Date Filing Date
DK510072AA DK131465B (da) 1971-10-29 1972-10-16 Analogifremgangsmåde til fremstilling af pyrimidinon-forbindelser.

Country Status (25)

Country Link
JP (2) JPS5337870B2 (fr)
AR (2) AR198798A1 (fr)
AT (2) AT320656B (fr)
AU (1) AU467600B2 (fr)
BE (1) BE790125A (fr)
CA (1) CA980778A (fr)
CH (2) CH555832A (fr)
DE (3) DE2264657C2 (fr)
DK (1) DK131465B (fr)
EG (1) EG11013A (fr)
ES (2) ES407730A1 (fr)
FI (1) FI55503C (fr)
FR (1) FR2157865B1 (fr)
GB (2) GB1377308A (fr)
IE (1) IE37043B1 (fr)
IL (2) IL40458A (fr)
LU (1) LU66304A1 (fr)
NL (1) NL166470C (fr)
NO (1) NO136574C (fr)
PH (2) PH10129A (fr)
PL (2) PL84634B1 (fr)
SE (2) SE393376B (fr)
SU (2) SU498908A3 (fr)
YU (2) YU35125B (fr)
ZA (1) ZA727362B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (fr) * 1979-04-17 1980-11-01
JPS5752409Y2 (fr) * 1979-11-05 1982-11-15
DE3222914A1 (de) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg Substituierte 5-phenylthio-6-amino-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPH0655686B2 (ja) * 1988-08-30 1994-07-27 宇部興産株式会社 ｐ−ブロモフェノキシアセトアルデヒドジアルキルアセタール類の製造方法
KR101577554B1 (ko) 2005-08-22 2015-12-14 멜리어 파마슈티칼스 아이, 인코포레이티드 Ｌｙｎ 키나제 활성의 조절 및 관련된 장애의 치료를 위한 방법 및 제제
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
US20130158055A1 (en) 2010-05-28 2013-06-20 Andrew G. Reaume Prevention Of Pancreatic Beta Cell Degeneration
CA3059432A1 (fr) 2017-04-10 2018-10-18 Melior Pharmaceuticals I, Inc. Compositions comprenant un activateur de lyn kinase et un agoniste de trpm8

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951432A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
ES407730A1 (es) 1976-01-16
SE397090B (sv) 1977-10-17
ES436624A1 (es) 1977-02-01
PH11594A (en) 1978-03-31
PH10129A (en) 1976-09-02
DE2264374B2 (de) 1980-08-07
NL166470C (nl) 1981-08-17
FI55503C (fi) 1979-08-10
SE7505279L (sv) 1975-05-06
ZA727362B (en) 1973-11-28
CA980778A (en) 1975-12-30
PL84634B1 (fr) 1976-04-30
IL40458A0 (en) 1972-11-28
DK131465C (fr) 1975-12-08
GB1377720A (en) 1974-12-18
SU505362A3 (ru) 1976-02-28
DE2248741B2 (de) 1974-11-14
YU255172A (en) 1980-03-15
IL48790A (en) 1976-05-31
CH555832A (fr) 1974-11-15
PL89852B1 (fr) 1976-12-31
DE2264657C2 (de) 1982-09-16
JPS5422995B2 (fr) 1979-08-10
IL48790A0 (en) 1976-03-31
DE2248741A1 (de) 1973-05-03
IE37043L (en) 1973-04-29
DE2264374A1 (de) 1973-05-24
CH549579A (fr) 1974-05-31
FR2157865B1 (fr) 1975-10-31
FI55503B (fi) 1979-04-30
AT320656B (de) 1975-02-25
EG11013A (en) 1976-11-30
NO136574B (fr) 1977-06-20
YU35125B (en) 1980-09-25
JPS4852780A (fr) 1973-07-24
GB1377308A (en) 1974-12-11
SU498908A3 (ru) 1976-01-05
IE37043B1 (en) 1977-04-27
AU4722872A (en) 1974-04-04
SE393376B (sv) 1977-05-09
DE2264374C3 (de) 1981-07-23
LU66304A1 (fr) 1973-05-03
AR196263A1 (es) 1973-12-10
NO136574C (no) 1977-09-28
FR2157865A1 (fr) 1973-06-08
IL40458A (en) 1976-05-31
AR198798A1 (es) 1974-07-24
JPS5337870B2 (fr) 1978-10-12
DE2248741C3 (de) 1975-06-26
NL7213959A (fr) 1973-05-02
NL166470B (nl) 1981-03-16
YU99179A (en) 1981-08-31
AU467600B2 (en) 1975-12-04
DE2264657A1 (de) 1974-06-20
AT321308B (de) 1975-03-25
YU36295B (en) 1982-06-18
BE790125A (fr) 1973-04-16
JPS53116386A (en) 1978-10-11

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