EG11013A - Process for preparation of novel pyrimidinones and novel hydroxy pyrimidines - Google Patents

Process for preparation of novel pyrimidinones and novel hydroxy pyrimidines

Info

Publication number
EG11013A
EG11013A EG431/72A EG43172A EG11013A EG 11013 A EG11013 A EG 11013A EG 431/72 A EG431/72 A EG 431/72A EG 43172 A EG43172 A EG 43172A EG 11013 A EG11013 A EG 11013A
Authority
EG
Egypt
Prior art keywords
novel
pyrimidinones
preparation
hydroxy pyrimidines
pyrimidines
Prior art date
Application number
EG431/72A
Inventor
C Lipinski
J Stam
G George
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of EG11013A publication Critical patent/EG11013A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
EG431/72A 1971-10-29 1972-10-19 Process for preparation of novel pyrimidinones and novel hydroxy pyrimidines EG11013A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (1)

Publication Number Publication Date
EG11013A true EG11013A (en) 1976-11-30

Family

ID=22715935

Family Applications (1)

Application Number Title Priority Date Filing Date
EG431/72A EG11013A (en) 1971-10-29 1972-10-19 Process for preparation of novel pyrimidinones and novel hydroxy pyrimidines

Country Status (25)

Country Link
JP (2) JPS5337870B2 (en)
AR (2) AR198798A1 (en)
AT (2) AT321308B (en)
AU (1) AU467600B2 (en)
BE (1) BE790125A (en)
CA (1) CA980778A (en)
CH (2) CH549579A (en)
DE (3) DE2264657C2 (en)
DK (1) DK131465B (en)
EG (1) EG11013A (en)
ES (2) ES407730A1 (en)
FI (1) FI55503C (en)
FR (1) FR2157865B1 (en)
GB (2) GB1377308A (en)
IE (1) IE37043B1 (en)
IL (2) IL40458A (en)
LU (1) LU66304A1 (en)
NL (1) NL166470C (en)
NO (1) NO136574C (en)
PH (2) PH10129A (en)
PL (2) PL84634B1 (en)
SE (2) SE393376B (en)
SU (2) SU498908A3 (en)
YU (2) YU35125B (en)
ZA (1) ZA727362B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (en) * 1979-04-17 1980-11-01
JPS5752409Y2 (en) * 1979-11-05 1982-11-15
DE3222914A1 (en) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg SUBSTITUTED 5-PHENYLTHIO-6-AMINO-PYRIMIDINONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE, AND PREPARATIONS CONTAINING THESE COMPOUNDS
JPH0655686B2 (en) * 1988-08-30 1994-07-27 宇部興産株式会社 Process for producing p-bromophenoxyacetaldehyde dialkyl acetals
CA2620065C (en) 2005-08-22 2011-03-29 Melior Discovery, Inc. Methods and formulations for modulating lyn kinase activity and treating related disorders
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
US20130158055A1 (en) 2010-05-28 2013-06-20 Andrew G. Reaume Prevention Of Pancreatic Beta Cell Degeneration
BR112019021140A2 (en) 2017-04-10 2020-05-19 Univ Louisiana State composition, method to reduce blood glucose levels, weight gain or fat deposit levels, or treatment, adipocyte beige induction method or preventing pancreatic beta cell degeneration, and lyn kinase activator and agonist of trpm8 for use in reducing blood glucose levels, weight gain or fat deposit levels, or treatment.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951432A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
PL84634B1 (en) 1976-04-30
SU498908A3 (en) 1976-01-05
NO136574B (en) 1977-06-20
YU36295B (en) 1982-06-18
IE37043B1 (en) 1977-04-27
DE2264374C3 (en) 1981-07-23
DK131465B (en) 1975-07-21
FI55503C (en) 1979-08-10
NO136574C (en) 1977-09-28
IL48790A0 (en) 1976-03-31
DK131465C (en) 1975-12-08
PH10129A (en) 1976-09-02
JPS5337870B2 (en) 1978-10-12
IL40458A (en) 1976-05-31
IL40458A0 (en) 1972-11-28
FR2157865B1 (en) 1975-10-31
CH549579A (en) 1974-05-31
AR198798A1 (en) 1974-07-24
NL166470B (en) 1981-03-16
DE2264657C2 (en) 1982-09-16
JPS53116386A (en) 1978-10-11
FR2157865A1 (en) 1973-06-08
IE37043L (en) 1973-04-29
AU467600B2 (en) 1975-12-04
YU35125B (en) 1980-09-25
DE2264374A1 (en) 1973-05-24
LU66304A1 (en) 1973-05-03
PH11594A (en) 1978-03-31
DE2248741A1 (en) 1973-05-03
AR196263A1 (en) 1973-12-10
SE397090B (en) 1977-10-17
CH555832A (en) 1974-11-15
DE2264657A1 (en) 1974-06-20
DE2248741B2 (en) 1974-11-14
SE7505279L (en) 1975-05-06
JPS5422995B2 (en) 1979-08-10
NL7213959A (en) 1973-05-02
CA980778A (en) 1975-12-30
DE2248741C3 (en) 1975-06-26
FI55503B (en) 1979-04-30
ES436624A1 (en) 1977-02-01
IL48790A (en) 1976-05-31
AT321308B (en) 1975-03-25
JPS4852780A (en) 1973-07-24
AT320656B (en) 1975-02-25
SE393376B (en) 1977-05-09
GB1377720A (en) 1974-12-18
ZA727362B (en) 1973-11-28
GB1377308A (en) 1974-12-11
BE790125A (en) 1973-04-16
SU505362A3 (en) 1976-02-28
ES407730A1 (en) 1976-01-16
PL89852B1 (en) 1976-12-31
YU255172A (en) 1980-03-15
NL166470C (en) 1981-08-17
AU4722872A (en) 1974-04-04
DE2264374B2 (en) 1980-08-07
YU99179A (en) 1981-08-31

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