BE790125A - NEW PYRIMIDINONES AND NEW HYDROXYPYRIMIDINES - Google Patents

NEW PYRIMIDINONES AND NEW HYDROXYPYRIMIDINES

Info

Publication number
BE790125A
BE790125A BE790125DA BE790125A BE 790125 A BE790125 A BE 790125A BE 790125D A BE790125D A BE 790125DA BE 790125 A BE790125 A BE 790125A
Authority
BE
Belgium
Prior art keywords
new
hydroxypyrimidines
pyrimidinones
new pyrimidinones
new hydroxypyrimidines
Prior art date
Application number
Other languages
French (fr)
Inventor
Lipinski
J G Stam
G G Deangelis
H-J E Hess
C A Lipinski
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Publication date
Publication of BE790125A publication Critical patent/BE790125A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
BE790125D 1971-10-29 NEW PYRIMIDINONES AND NEW HYDROXYPYRIMIDINES BE790125A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (1)

Publication Number Publication Date
BE790125A true BE790125A (en) 1973-04-16

Family

ID=22715935

Family Applications (1)

Application Number Title Priority Date Filing Date
BE790125D BE790125A (en) 1971-10-29 NEW PYRIMIDINONES AND NEW HYDROXYPYRIMIDINES

Country Status (25)

Country Link
JP (2) JPS5337870B2 (en)
AR (2) AR198798A1 (en)
AT (2) AT320656B (en)
AU (1) AU467600B2 (en)
BE (1) BE790125A (en)
CA (1) CA980778A (en)
CH (2) CH549579A (en)
DE (3) DE2264657C2 (en)
DK (1) DK131465B (en)
EG (1) EG11013A (en)
ES (2) ES407730A1 (en)
FI (1) FI55503C (en)
FR (1) FR2157865B1 (en)
GB (2) GB1377308A (en)
IE (1) IE37043B1 (en)
IL (2) IL40458A (en)
LU (1) LU66304A1 (en)
NL (1) NL166470C (en)
NO (1) NO136574C (en)
PH (2) PH10129A (en)
PL (2) PL84634B1 (en)
SE (2) SE393376B (en)
SU (2) SU498908A3 (en)
YU (2) YU35125B (en)
ZA (1) ZA727362B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (en) * 1979-04-17 1980-11-01
JPS5752409Y2 (en) * 1979-11-05 1982-11-15
DE3222914A1 (en) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg SUBSTITUTED 5-PHENYLTHIO-6-AMINO-PYRIMIDINONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE, AND PREPARATIONS CONTAINING THESE COMPOUNDS
JPH0655686B2 (en) * 1988-08-30 1994-07-27 宇部興産株式会社 Process for producing p-bromophenoxyacetaldehyde dialkyl acetals
US7776870B2 (en) 2005-08-22 2010-08-17 Melior Pharmaceuticals I, Inc. Methods for modulating Lyn kinase activity and treating related disorders
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
WO2011150300A1 (en) 2010-05-28 2011-12-01 Melior Pharmaceuticals I, Inc. Prevention of pancreatic beta cell degeneration
BR112019021140A2 (en) 2017-04-10 2020-05-19 Univ Louisiana State composition, method to reduce blood glucose levels, weight gain or fat deposit levels, or treatment, adipocyte beige induction method or preventing pancreatic beta cell degeneration, and lyn kinase activator and agonist of trpm8 for use in reducing blood glucose levels, weight gain or fat deposit levels, or treatment.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951431A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
IL48790A0 (en) 1976-03-31
CH555832A (en) 1974-11-15
AR198798A1 (en) 1974-07-24
NL7213959A (en) 1973-05-02
PH11594A (en) 1978-03-31
ES407730A1 (en) 1976-01-16
YU36295B (en) 1982-06-18
JPS4852780A (en) 1973-07-24
SE397090B (en) 1977-10-17
FI55503B (en) 1979-04-30
YU99179A (en) 1981-08-31
FI55503C (en) 1979-08-10
AR196263A1 (en) 1973-12-10
FR2157865A1 (en) 1973-06-08
CH549579A (en) 1974-05-31
DK131465B (en) 1975-07-21
IE37043L (en) 1973-04-29
DE2264374A1 (en) 1973-05-24
SE393376B (en) 1977-05-09
JPS5337870B2 (en) 1978-10-12
NO136574C (en) 1977-09-28
YU35125B (en) 1980-09-25
ZA727362B (en) 1973-11-28
AT321308B (en) 1975-03-25
FR2157865B1 (en) 1975-10-31
AU4722872A (en) 1974-04-04
PH10129A (en) 1976-09-02
JPS5422995B2 (en) 1979-08-10
YU255172A (en) 1980-03-15
DK131465C (en) 1975-12-08
SE7505279L (en) 1975-05-06
EG11013A (en) 1976-11-30
NL166470B (en) 1981-03-16
SU498908A3 (en) 1976-01-05
IE37043B1 (en) 1977-04-27
JPS53116386A (en) 1978-10-11
DE2248741A1 (en) 1973-05-03
DE2248741C3 (en) 1975-06-26
ES436624A1 (en) 1977-02-01
LU66304A1 (en) 1973-05-03
DE2264374C3 (en) 1981-07-23
AT320656B (en) 1975-02-25
IL40458A (en) 1976-05-31
DE2264657A1 (en) 1974-06-20
NL166470C (en) 1981-08-17
CA980778A (en) 1975-12-30
NO136574B (en) 1977-06-20
GB1377308A (en) 1974-12-11
DE2264657C2 (en) 1982-09-16
GB1377720A (en) 1974-12-18
IL40458A0 (en) 1972-11-28
IL48790A (en) 1976-05-31
DE2248741B2 (en) 1974-11-14
DE2264374B2 (en) 1980-08-07
PL89852B1 (en) 1976-12-31
PL84634B1 (en) 1976-04-30
SU505362A3 (en) 1976-02-28
AU467600B2 (en) 1975-12-04

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: PFIZER INC

Effective date: 19841016