YU35125B - Process for preparing novel pyrimidinone derivatives - Google Patents

Process for preparing novel pyrimidinone derivatives

Info

Publication number
YU35125B
YU35125B YU2551/72A YU255172A YU35125B YU 35125 B YU35125 B YU 35125B YU 2551/72 A YU2551/72 A YU 2551/72A YU 255172 A YU255172 A YU 255172A YU 35125 B YU35125 B YU 35125B
Authority
YU
Yugoslavia
Prior art keywords
preparing novel
pyrimidinone derivatives
novel pyrimidinone
derivatives
preparing
Prior art date
Application number
YU2551/72A
Other versions
YU255172A (en
Inventor
Lipinski Andrew Christopher
Andrew Christopher Lipinski
Stam Gerritt John
Gerritt John Stam
Deangelis George Gerald
George Gerald Deangelis
Hess Ernst Jurgen-Hans
Ernst Jurgen-Hans Hess
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of YU255172A publication Critical patent/YU255172A/en
Publication of YU35125B publication Critical patent/YU35125B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56One oxygen atom and one sulfur atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
YU2551/72A 1971-10-29 1972-10-12 Process for preparing novel pyrimidinone derivatives YU35125B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (2)

Publication Number Publication Date
YU255172A YU255172A (en) 1980-03-15
YU35125B true YU35125B (en) 1980-09-25

Family

ID=22715935

Family Applications (2)

Application Number Title Priority Date Filing Date
YU2551/72A YU35125B (en) 1971-10-29 1972-10-12 Process for preparing novel pyrimidinone derivatives
YU991/79A YU36295B (en) 1971-10-29 1979-04-25 Process for obtaining novel hydroxy-pyrimidines

Family Applications After (1)

Application Number Title Priority Date Filing Date
YU991/79A YU36295B (en) 1971-10-29 1979-04-25 Process for obtaining novel hydroxy-pyrimidines

Country Status (25)

Country Link
JP (2) JPS5337870B2 (en)
AR (2) AR198798A1 (en)
AT (2) AT321308B (en)
AU (1) AU467600B2 (en)
BE (1) BE790125A (en)
CA (1) CA980778A (en)
CH (2) CH555832A (en)
DE (3) DE2264374C3 (en)
DK (1) DK131465B (en)
EG (1) EG11013A (en)
ES (2) ES407730A1 (en)
FI (1) FI55503C (en)
FR (1) FR2157865B1 (en)
GB (2) GB1377308A (en)
IE (1) IE37043B1 (en)
IL (2) IL40458A (en)
LU (1) LU66304A1 (en)
NL (1) NL166470C (en)
NO (1) NO136574C (en)
PH (2) PH10129A (en)
PL (2) PL84634B1 (en)
SE (2) SE393376B (en)
SU (2) SU498908A3 (en)
YU (2) YU35125B (en)
ZA (1) ZA727362B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (en) * 1979-04-17 1980-11-01
JPS5752409Y2 (en) * 1979-11-05 1982-11-15
DE3222914A1 (en) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg SUBSTITUTED 5-PHENYLTHIO-6-AMINO-PYRIMIDINONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE, AND PREPARATIONS CONTAINING THESE COMPOUNDS
JPH0655686B2 (en) * 1988-08-30 1994-07-27 宇部興産株式会社 Process for producing p-bromophenoxyacetaldehyde dialkyl acetals
US7776870B2 (en) 2005-08-22 2010-08-17 Melior Pharmaceuticals I, Inc. Methods for modulating Lyn kinase activity and treating related disorders
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
US20130158055A1 (en) 2010-05-28 2013-06-20 Andrew G. Reaume Prevention Of Pancreatic Beta Cell Degeneration
JP7182605B2 (en) 2017-04-10 2022-12-02 メリオール・ファーマスーティカルズ・ワン・インコーポレイテッド Compositions comprising a lyn kinase activator and a TRPM8 agonist and their use in the manufacture of medicaments

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951432A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
IL40458A (en) 1976-05-31
JPS4852780A (en) 1973-07-24
IE37043B1 (en) 1977-04-27
SU498908A3 (en) 1976-01-05
ZA727362B (en) 1973-11-28
DE2264374B2 (en) 1980-08-07
JPS5422995B2 (en) 1979-08-10
AR196263A1 (en) 1973-12-10
FI55503B (en) 1979-04-30
DE2264657A1 (en) 1974-06-20
DE2248741B2 (en) 1974-11-14
IL40458A0 (en) 1972-11-28
GB1377720A (en) 1974-12-18
FI55503C (en) 1979-08-10
AU4722872A (en) 1974-04-04
ES407730A1 (en) 1976-01-16
DE2264374C3 (en) 1981-07-23
YU255172A (en) 1980-03-15
DE2248741C3 (en) 1975-06-26
GB1377308A (en) 1974-12-11
JPS5337870B2 (en) 1978-10-12
CH549579A (en) 1974-05-31
NL166470B (en) 1981-03-16
LU66304A1 (en) 1973-05-03
AT320656B (en) 1975-02-25
DK131465C (en) 1975-12-08
PH11594A (en) 1978-03-31
JPS53116386A (en) 1978-10-11
CA980778A (en) 1975-12-30
AT321308B (en) 1975-03-25
PH10129A (en) 1976-09-02
IE37043L (en) 1973-04-29
BE790125A (en) 1973-04-16
YU36295B (en) 1982-06-18
SU505362A3 (en) 1976-02-28
NO136574C (en) 1977-09-28
DE2264374A1 (en) 1973-05-24
PL89852B1 (en) 1976-12-31
EG11013A (en) 1976-11-30
AU467600B2 (en) 1975-12-04
ES436624A1 (en) 1977-02-01
IL48790A0 (en) 1976-03-31
SE7505279L (en) 1975-05-06
AR198798A1 (en) 1974-07-24
NL166470C (en) 1981-08-17
DE2264657C2 (en) 1982-09-16
FR2157865A1 (en) 1973-06-08
NO136574B (en) 1977-06-20
IL48790A (en) 1976-05-31
DE2248741A1 (en) 1973-05-03
YU99179A (en) 1981-08-31
DK131465B (en) 1975-07-21
FR2157865B1 (en) 1975-10-31
PL84634B1 (en) 1976-04-30
SE393376B (en) 1977-05-09
SE397090B (en) 1977-10-17
CH555832A (en) 1974-11-15
NL7213959A (en) 1973-05-02

Similar Documents

Publication Publication Date Title
YU298072A (en) Process for preparing isothiocyanobenzazoles
YU125072A (en) Process for preparing prostanic acid derivatives
YU35027B (en) Process for preparing novel oxazolo-or thiazoloazepine derivatives
GB1406684A (en) Process for producing pyrimidine derivatives
YU216872A (en) Process for preparing cinnamoyl-5-benzofuran derivatives
CS180608B2 (en) Process for preparing dialkoxyxanthogendisulfines
CS190400B2 (en) Process for preparing hetacephalexine
YU204172A (en) Process for preparing 4-aza-benzimidazoles
YU230872A (en) Process for preparing pyrimidine derivatives
YU255172A (en) Process for preparing novel pyrimidinone derivatives
YU211971A (en) Process for preparing novel thio-piperidine derivatives
JPS53127458A (en) Process for preparing alphaaisopropylidenee11 azethidineacetate
YU35261B (en) Process for preparing tertramisole
YU34999B (en) Process for preparing novel substituted n-methalyl-n-phenyl-amino-imidazolines
CS190382B2 (en) Process for preparing 3-alkylthiomethyl-7-acylamidocephalosporines
YU239672A (en) Process for preparing steroid-21-alcohols
CS190379B2 (en) Process for preparing penicilinamine
GB1400875A (en) Process for preparing cyclicdicarboximidophosphonothioates
YU264478A (en) Process for preparing novel imidazole derivatives
YU15272A (en) Process for preparing dihalo-6-phenyltriazolobenzodiazepine-5-n-oxides
CS190384B2 (en) Process for preparing rennete
YU34618B (en) Process for preparing 1-allyl-2-amino-methyl-pyrrolidines
YU59472A (en) Process for preparing lumilysergol derivatives
KR780000157B1 (en) Process for preparing triazinomidazoles
YU124772A (en) Process for preparing new 3-hydrazinopyridazine derivatives