CH549579A - PROCESS FOR THE PREPARATION OF NEW HYDROXY-PYRIMIDINES. - Google Patents

PROCESS FOR THE PREPARATION OF NEW HYDROXY-PYRIMIDINES.

Info

Publication number
CH549579A
CH549579A CH165674A CH165674A CH549579A CH 549579 A CH549579 A CH 549579A CH 165674 A CH165674 A CH 165674A CH 165674 A CH165674 A CH 165674A CH 549579 A CH549579 A CH 549579A
Authority
CH
Switzerland
Prior art keywords
pyrimidines
preparation
new hydroxy
hydroxy
new
Prior art date
Application number
CH165674A
Other languages
French (fr)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CH549579A publication Critical patent/CH549579A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CH165674A 1971-10-29 1972-10-16 PROCESS FOR THE PREPARATION OF NEW HYDROXY-PYRIMIDINES. CH549579A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (1)

Publication Number Publication Date
CH549579A true CH549579A (en) 1974-05-31

Family

ID=22715935

Family Applications (2)

Application Number Title Priority Date Filing Date
CH1507872A CH555832A (en) 1971-10-29 1972-10-16 PROCESS FOR THE PREPARATION OF NEW PYRIMIDINONES.
CH165674A CH549579A (en) 1971-10-29 1972-10-16 PROCESS FOR THE PREPARATION OF NEW HYDROXY-PYRIMIDINES.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CH1507872A CH555832A (en) 1971-10-29 1972-10-16 PROCESS FOR THE PREPARATION OF NEW PYRIMIDINONES.

Country Status (25)

Country Link
JP (2) JPS5337870B2 (en)
AR (2) AR198798A1 (en)
AT (2) AT321308B (en)
AU (1) AU467600B2 (en)
BE (1) BE790125A (en)
CA (1) CA980778A (en)
CH (2) CH555832A (en)
DE (3) DE2248741C3 (en)
DK (1) DK131465B (en)
EG (1) EG11013A (en)
ES (2) ES407730A1 (en)
FI (1) FI55503C (en)
FR (1) FR2157865B1 (en)
GB (2) GB1377308A (en)
IE (1) IE37043B1 (en)
IL (2) IL40458A (en)
LU (1) LU66304A1 (en)
NL (1) NL166470C (en)
NO (1) NO136574C (en)
PH (2) PH10129A (en)
PL (2) PL89852B1 (en)
SE (2) SE393376B (en)
SU (2) SU498908A3 (en)
YU (2) YU35125B (en)
ZA (1) ZA727362B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (en) * 1979-04-17 1980-11-01
JPS5752409Y2 (en) * 1979-11-05 1982-11-15
DE3222914A1 (en) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg SUBSTITUTED 5-PHENYLTHIO-6-AMINO-PYRIMIDINONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE, AND PREPARATIONS CONTAINING THESE COMPOUNDS
JPH0655686B2 (en) * 1988-08-30 1994-07-27 宇部興産株式会社 Process for producing p-bromophenoxyacetaldehyde dialkyl acetals
KR101452518B1 (en) 2005-08-22 2014-10-21 멜리어 파마슈티칼스 아이, 인코포레이티드 Methods and formulations for modulating lyn kinase activity and treating related disorders
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
WO2011150300A1 (en) 2010-05-28 2011-12-01 Melior Pharmaceuticals I, Inc. Prevention of pancreatic beta cell degeneration
CN110785170B (en) 2017-04-10 2023-03-28 梅里奥尔医药I公司 Treatment of adipocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951432A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
PL84634B1 (en) 1976-04-30
DK131465B (en) 1975-07-21
DE2264374C3 (en) 1981-07-23
IL40458A (en) 1976-05-31
FI55503B (en) 1979-04-30
DE2264374B2 (en) 1980-08-07
DE2248741B2 (en) 1974-11-14
NL166470C (en) 1981-08-17
ZA727362B (en) 1973-11-28
SE7505279L (en) 1975-05-06
NO136574C (en) 1977-09-28
DE2248741C3 (en) 1975-06-26
CH555832A (en) 1974-11-15
JPS5422995B2 (en) 1979-08-10
FI55503C (en) 1979-08-10
LU66304A1 (en) 1973-05-03
IL48790A (en) 1976-05-31
SE397090B (en) 1977-10-17
AU467600B2 (en) 1975-12-04
JPS5337870B2 (en) 1978-10-12
NL7213959A (en) 1973-05-02
SU498908A3 (en) 1976-01-05
DK131465C (en) 1975-12-08
PH10129A (en) 1976-09-02
SU505362A3 (en) 1976-02-28
DE2264657A1 (en) 1974-06-20
YU36295B (en) 1982-06-18
FR2157865A1 (en) 1973-06-08
DE2248741A1 (en) 1973-05-03
IE37043L (en) 1973-04-29
BE790125A (en) 1973-04-16
PH11594A (en) 1978-03-31
IE37043B1 (en) 1977-04-27
JPS53116386A (en) 1978-10-11
AT321308B (en) 1975-03-25
SE393376B (en) 1977-05-09
YU35125B (en) 1980-09-25
AR198798A1 (en) 1974-07-24
DE2264657C2 (en) 1982-09-16
AT320656B (en) 1975-02-25
IL40458A0 (en) 1972-11-28
AR196263A1 (en) 1973-12-10
NO136574B (en) 1977-06-20
YU255172A (en) 1980-03-15
DE2264374A1 (en) 1973-05-24
AU4722872A (en) 1974-04-04
PL89852B1 (en) 1976-12-31
FR2157865B1 (en) 1975-10-31
ES436624A1 (en) 1977-02-01
GB1377308A (en) 1974-12-11
CA980778A (en) 1975-12-30
YU99179A (en) 1981-08-31
EG11013A (en) 1976-11-30
NL166470B (en) 1981-03-16
ES407730A1 (en) 1976-01-16
IL48790A0 (en) 1976-03-31
GB1377720A (en) 1974-12-18
JPS4852780A (en) 1973-07-24

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Legal Events

Date Code Title Description
PL Patent ceased