AT321308B - Verfahren zur Herstellung neuer Pyrimidinonderivate und ihrer Salze - Google Patents

Verfahren zur Herstellung neuer Pyrimidinonderivate und ihrer Salze

Info

Publication number
AT321308B
AT321308B AT858972A AT858972A AT321308B AT 321308 B AT321308 B AT 321308B AT 858972 A AT858972 A AT 858972A AT 858972 A AT858972 A AT 858972A AT 321308 B AT321308 B AT 321308B
Authority
AT
Austria
Prior art keywords
salts
preparation
pyrimidinone derivatives
new
new pyrimidinone
Prior art date
Application number
AT858972A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of AT321308B publication Critical patent/AT321308B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/56—One oxygen atom and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
AT858972A 1971-10-29 1972-10-06 Verfahren zur Herstellung neuer Pyrimidinonderivate und ihrer Salze AT321308B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19400671A 1971-10-29 1971-10-29

Publications (1)

Publication Number Publication Date
AT321308B true AT321308B (de) 1975-03-25

Family

ID=22715935

Family Applications (2)

Application Number Title Priority Date Filing Date
AT00933/74A AT320656B (de) 1971-10-29 1972-10-06 Vzh neuer hydroxypirimidinderivate und ihrer salze
AT858972A AT321308B (de) 1971-10-29 1972-10-06 Verfahren zur Herstellung neuer Pyrimidinonderivate und ihrer Salze

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT00933/74A AT320656B (de) 1971-10-29 1972-10-06 Vzh neuer hydroxypirimidinderivate und ihrer salze

Country Status (25)

Country Link
JP (2) JPS5337870B2 (de)
AR (2) AR198798A1 (de)
AT (2) AT320656B (de)
AU (1) AU467600B2 (de)
BE (1) BE790125A (de)
CA (1) CA980778A (de)
CH (2) CH549579A (de)
DE (3) DE2264374C3 (de)
DK (1) DK131465B (de)
EG (1) EG11013A (de)
ES (2) ES407730A1 (de)
FI (1) FI55503C (de)
FR (1) FR2157865B1 (de)
GB (2) GB1377308A (de)
IE (1) IE37043B1 (de)
IL (2) IL40458A (de)
LU (1) LU66304A1 (de)
NL (1) NL166470C (de)
NO (1) NO136574C (de)
PH (2) PH10129A (de)
PL (2) PL89852B1 (de)
SE (2) SE393376B (de)
SU (2) SU498908A3 (de)
YU (2) YU35125B (de)
ZA (1) ZA727362B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55151912U (de) * 1979-04-17 1980-11-01
JPS5752409Y2 (de) * 1979-11-05 1982-11-15
DE3222914A1 (de) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg Substituierte 5-phenylthio-6-amino-pyrimidinone, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen
JPH0655686B2 (ja) * 1988-08-30 1994-07-27 宇部興産株式会社 ｐ−ブロモフェノキシアセトアルデヒドジアルキルアセタール類の製造方法
EP1924262B1 (de) 2005-08-22 2011-11-16 Melior Pharmaceuticals I, Inc. Verfahren und formulierungen zur modulierung von lyn-kinaseaktivität und behandlung assoziierter erkrankungen
US8552184B2 (en) 2008-07-03 2013-10-08 Melior Pharmaceuticals I, Inc. Compounds and methods for treating disorders related to glucose metabolism
SG11201909406VA (en) 2017-04-10 2019-11-28 Melior Pharmaceuticals I Inc Treatment of adipocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2913462A (en) * 1959-11-17 Eahl h
GB951432A (en) * 1959-03-17 1964-03-04 Wellcome Found Pyrimidine derivatives and the manufacture thereof

Also Published As

Publication number Publication date
CA980778A (en) 1975-12-30
ES407730A1 (es) 1976-01-16
BE790125A (fr) 1973-04-16
FR2157865A1 (de) 1973-06-08
AU467600B2 (en) 1975-12-04
IE37043L (en) 1973-04-29
DE2264374C3 (de) 1981-07-23
AR196263A1 (es) 1973-12-10
NL7213959A (de) 1973-05-02
DE2264374A1 (de) 1973-05-24
DE2248741B2 (de) 1974-11-14
FR2157865B1 (de) 1975-10-31
AT320656B (de) 1975-02-25
PH11594A (en) 1978-03-31
LU66304A1 (de) 1973-05-03
JPS4852780A (de) 1973-07-24
AR198798A1 (es) 1974-07-24
SU505362A3 (ru) 1976-02-28
DK131465B (da) 1975-07-21
GB1377308A (en) 1974-12-11
YU255172A (en) 1980-03-15
DE2264657A1 (de) 1974-06-20
AU4722872A (en) 1974-04-04
ES436624A1 (es) 1977-02-01
YU35125B (en) 1980-09-25
IL48790A (en) 1976-05-31
YU99179A (en) 1981-08-31
NL166470C (nl) 1981-08-17
NO136574B (de) 1977-06-20
PH10129A (en) 1976-09-02
PL84634B1 (de) 1976-04-30
EG11013A (en) 1976-11-30
DE2248741C3 (de) 1975-06-26
SE397090B (sv) 1977-10-17
YU36295B (en) 1982-06-18
PL89852B1 (de) 1976-12-31
ZA727362B (en) 1973-11-28
FI55503C (fi) 1979-08-10
NO136574C (no) 1977-09-28
IL48790A0 (en) 1976-03-31
FI55503B (fi) 1979-04-30
SE7505279L (sv) 1975-05-06
DK131465C (de) 1975-12-08
JPS53116386A (en) 1978-10-11
JPS5422995B2 (de) 1979-08-10
IL40458A (en) 1976-05-31
DE2264374B2 (de) 1980-08-07
SE393376B (sv) 1977-05-09
IE37043B1 (en) 1977-04-27
JPS5337870B2 (de) 1978-10-12
DE2264657C2 (de) 1982-09-16
GB1377720A (en) 1974-12-18
DE2248741A1 (de) 1973-05-03
NL166470B (nl) 1981-03-16
IL40458A0 (en) 1972-11-28
SU498908A3 (ru) 1976-01-05
CH549579A (fr) 1974-05-31
CH555832A (fr) 1974-11-15

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee