|
US1265208A
(en)
|
1915-09-07 |
1918-05-07 |
Edward C Kahn |
Liquid-fuel burner.
|
|
JPH0637520B2
(ja)
*
|
1985-07-03 |
1994-05-18 |
味の素株式会社 |
ポリペプチド
|
|
EP0272253A4
(en)
|
1986-03-07 |
1990-02-05 |
Massachusetts Inst Technology |
METHOD FOR IMPROVING GLYCOPROTE INSTABILITY.
|
|
US4973577A
(en)
*
|
1986-04-04 |
1990-11-27 |
The Salk Institute For Biological Studies |
FSH-releasing peptides
|
|
US5080891A
(en)
|
1987-08-03 |
1992-01-14 |
Ddi Pharmaceuticals, Inc. |
Conjugates of superoxide dismutase coupled to high molecular weight polyalkylene glycols
|
|
WO1992004913A1
(en)
*
|
1990-09-13 |
1992-04-02 |
Children's Hospital Medical Center Of Northern California |
Method for increasing red blood cell production by treatment with activin or activin-related peptides
|
|
US5118667A
(en)
*
|
1991-05-03 |
1992-06-02 |
Celtrix Pharmaceuticals, Inc. |
Bone growth factors and inhibitors of bone resorption for promoting bone formation
|
|
US6162896A
(en)
*
|
1991-05-10 |
2000-12-19 |
The Salk Institute For Biological Studies |
Recombinant vertebrate activin receptors
|
|
CA2086327A1
(en)
|
1991-05-10 |
1992-11-11 |
Lawrence S. Mathews |
Cloning and recombinant production of receptor(s) of the activin/tgf- .beta. superfamily
|
|
US20050186593A1
(en)
|
1991-05-10 |
2005-08-25 |
The Salk Institute For Biological Studies |
Cloning and recombinant production of CRF receptor(s)
|
|
US5885794A
(en)
*
|
1991-05-10 |
1999-03-23 |
The Salk Institute For Biological Studies |
Recombinant production of vertebrate activin receptor polypeptides and identification of receptor DNAs in the activin/TGF-β superfamily
|
|
US6287816B1
(en)
|
1991-06-25 |
2001-09-11 |
Genetics Institute, Inc. |
BMP-9 compositions
|
|
WO1993000432A1
(en)
|
1991-06-25 |
1993-01-07 |
Genetics Institute, Inc. |
Bmp-9 compositions
|
|
US6692925B1
(en)
*
|
1992-11-17 |
2004-02-17 |
Ludwig Institute For Cancer Research |
Proteins having serine/threonine kinase domains, corresponding nucleic acid molecules, and their use
|
|
US5808007A
(en)
|
1993-01-12 |
1998-09-15 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor-3
|
|
US5354934A
(en)
|
1993-02-04 |
1994-10-11 |
Amgen Inc. |
Pulmonary administration of erythropoietin
|
|
US5637480A
(en)
|
1993-05-12 |
1997-06-10 |
Genetics Institute, Inc. |
DNA molecules encoding bone morphogenetic protein-10
|
|
AU677849B2
(en)
|
1993-05-12 |
1997-05-08 |
Genetics Institute, Llc |
BMP-10 compositions
|
|
US5677196A
(en)
|
1993-05-18 |
1997-10-14 |
University Of Utah Research Foundation |
Apparatus and methods for multi-analyte homogeneous fluoro-immunoassays
|
|
US5831050A
(en)
*
|
1993-06-07 |
1998-11-03 |
Creative Biomolecules, Inc. |
Morphogen cell surface receptor
|
|
JPH09503673A
(ja)
|
1993-10-14 |
1997-04-15 |
プレジデント・アンド・フエローズ・オブ・ハーバード・カレツジ |
ニューロン細胞の誘導および維持法
|
|
US5525490A
(en)
|
1994-03-29 |
1996-06-11 |
Onyx Pharmaceuticals, Inc. |
Reverse two-hybrid method
|
|
US5658876A
(en)
*
|
1994-04-28 |
1997-08-19 |
The General Hospital Corporation |
Activin antagonists as novel contraceptives
|
|
US5760010A
(en)
|
1995-01-01 |
1998-06-02 |
Klein; Ira |
Method of treating liver disorders with a macrolide antibiotic
|
|
US5814565A
(en)
|
1995-02-23 |
1998-09-29 |
University Of Utah Research Foundation |
Integrated optic waveguide immunosensor
|
|
DE69636866D1
(en)
|
1995-04-11 |
2007-03-15 |
Gen Hospital Corp |
Reverse "two-hybrid"-systeme
|
|
US6132988A
(en)
*
|
1995-10-27 |
2000-10-17 |
Takeda Chemical Industries, Ltd. |
DNA encoding a neuronal cell-specific receptor protein
|
|
GB9526131D0
(en)
|
1995-12-21 |
1996-02-21 |
Celltech Therapeutics Ltd |
Recombinant chimeric receptors
|
|
US6004780A
(en)
|
1996-03-26 |
1999-12-21 |
Human Genome Sciences, Inc. |
Growth factor HTTER36
|
|
US20050244867A1
(en)
|
1996-03-26 |
2005-11-03 |
Human Genome Sciences, Inc. |
Growth factor HTTER36
|
|
US6372480B1
(en)
*
|
1996-04-19 |
2002-04-16 |
Mycogen Corporation |
Pesticidal proteins
|
|
CA2268001A1
(en)
|
1996-10-25 |
1998-05-07 |
G.D. Searle & Co. |
Circularly permuted erythropoietin receptor agonists
|
|
US6017534A
(en)
*
|
1996-11-20 |
2000-01-25 |
Ecogen, Inc. |
Hybrid Bacillus thuringiensis δ-endotoxins with novel broad-spectrum insecticidal activity
|
|
US6605699B1
(en)
*
|
1997-01-21 |
2003-08-12 |
Human Genome Sciences, Inc. |
Galectin-11 polypeptides
|
|
US6034062A
(en)
|
1997-03-13 |
2000-03-07 |
Genetics Institute, Inc. |
Bone morphogenetic protein (BMP)-9 compositions and their uses
|
|
US6231880B1
(en)
*
|
1997-05-30 |
2001-05-15 |
Susan P. Perrine |
Compositions and administration of compositions for the treatment of blood disorders
|
|
WO1999006559A1
(en)
|
1997-08-01 |
1999-02-11 |
The Johns Hopkins University School Of Medicine |
Methods to identify growth differentiation factor (gdf) receptors
|
|
US6656475B1
(en)
|
1997-08-01 |
2003-12-02 |
The Johns Hopkins University School Of Medicine |
Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same
|
|
US6891082B2
(en)
*
|
1997-08-01 |
2005-05-10 |
The Johns Hopkins University School Of Medicine |
Transgenic non-human animals expressing a truncated activintype II receptor
|
|
US6696260B1
(en)
*
|
1997-08-01 |
2004-02-24 |
The Johns Hopkins University School Of Medicine |
Methods to identify growth differentiation factor (GDF) binding proteins
|
|
US6953662B2
(en)
*
|
1997-08-29 |
2005-10-11 |
Human Genome Sciences, Inc. |
Follistatin-3
|
|
AU8921698A
(en)
|
1997-08-29 |
1999-03-16 |
Human Genome Sciences, Inc. |
Follistatin-3
|
|
ATE373712T1
(de)
|
1997-10-03 |
2007-10-15 |
Chugai Pharmaceutical Co Ltd |
Natürlicher menschlicher antikörper
|
|
US6696411B1
(en)
|
1998-04-22 |
2004-02-24 |
Cornell Research Foundation, Inc. |
Canine erythropoietin gene and recombinant protein
|
|
CA2343268A1
(en)
|
1998-09-17 |
2000-03-23 |
Eli Lilly And Company |
Protein formulations
|
|
CA2343715C
(en)
|
1998-09-22 |
2004-05-18 |
Long Yu |
New human growth differentiation factor encoding sequence and polypeptide encoded by such dna sequence and producing method thereof
|
|
US6472179B2
(en)
|
1998-09-25 |
2002-10-29 |
Regeneron Pharmaceuticals, Inc. |
Receptor based antagonists and methods of making and using
|
|
US6548634B1
(en)
|
1998-09-30 |
2003-04-15 |
Chiron Corporation |
Synthetic peptides having FGF receptor affinity
|
|
CN1342085A
(zh)
|
1998-10-30 |
2002-03-27 |
遗传研究所有限公司 |
通过p－选择素配体(psgl)拮抗剂抑制细胞素t细胞的分化
|
|
US6238860B1
(en)
|
1998-11-05 |
2001-05-29 |
Dyax Corp. |
Binding moieties for human parvovirus B19
|
|
US6777205B1
(en)
|
1998-11-06 |
2004-08-17 |
Sterrenbeld Biotechnologie North America, Inc. |
Host cells expressing recombinant human erythropoietin
|
|
US20040009535A1
(en)
|
1998-11-27 |
2004-01-15 |
Celltech R&D, Inc. |
Compositions and methods for increasing bone mineralization
|
|
DE60027135T2
(de)
|
1999-01-21 |
2007-01-11 |
Metamorphix, Inc. |
Inhibitoren für wachstumdifferenzierungsfaktor und ihre anwendungen
|
|
US6914128B1
(en)
|
1999-03-25 |
2005-07-05 |
Abbott Gmbh & Co. Kg |
Human antibodies that bind human IL-12 and methods for producing
|
|
EP1174149A1
(en)
|
1999-04-19 |
2002-01-23 |
Kyowa Hakko Kogyo Co., Ltd. |
Proliferation inhibitor for androgen-independent tumor
|
|
US6468543B1
(en)
*
|
1999-05-03 |
2002-10-22 |
Zymogenetics, Inc. |
Methods for promoting growth of bone using ZVEGF4
|
|
JP2003513681A
(ja)
|
1999-11-12 |
2003-04-15 |
マキシゲン・ホールディングス・リミテッド |
インターフェロンガンマ・コンジュゲート
|
|
CA2394576A1
(en)
|
1999-12-15 |
2001-06-21 |
Research Development Foundation |
Betaglycan as an inhibin receptor and uses thereof
|
|
US20030224501A1
(en)
|
2000-03-17 |
2003-12-04 |
Young Paul E. |
Bone morphogenic protein polynucleotides, polypeptides, and antibodies
|
|
JP4487376B2
(ja)
*
|
2000-03-31 |
2010-06-23 |
味の素株式会社 |
腎疾患治療剤
|
|
CA2408685C
(en)
|
2000-05-15 |
2011-02-01 |
F. Hoffmann-La Roche Ag |
Liquid pharmaceutical composition containing an erythropoietin derivate
|
|
US6627424B1
(en)
|
2000-05-26 |
2003-09-30 |
Mj Bioworks, Inc. |
Nucleic acid modifying enzymes
|
|
WO2002008277A2
(en)
|
2000-07-19 |
2002-01-31 |
Eli Lilly And Company |
Nucleic acids, vectors, host cells, polypeptides, and uses thereof
|
|
US6632180B1
(en)
|
2000-09-07 |
2003-10-14 |
John H. Laragh |
Method for evaluating and treating hypertension
|
|
DE10045591A1
(de)
|
2000-09-15 |
2002-04-04 |
Klaus Pfizenmaier |
Ortsspezifische, antikörpervermittelte Aktivierung proapoptotischer Zytokine - AMAIZe (Antibody-Mediated Apoptosis Inducing Zytokine)
|
|
US7087224B2
(en)
|
2000-10-31 |
2006-08-08 |
Amgen Inc. |
Method of treating anemia by administering IL-1ra
|
|
AU2002225670B2
(en)
|
2000-11-20 |
2006-05-11 |
The Board Of Trustees Of The University Of Illinois |
Membrane scaffold proteins
|
|
WO2002043759A2
(en)
|
2000-12-01 |
2002-06-06 |
Wyeth |
Method and composition for modulating bone growth
|
|
US20030082233A1
(en)
|
2000-12-01 |
2003-05-01 |
Lyons Karen M. |
Method and composition for modulating bone growth
|
|
TW200526779A
(en)
*
|
2001-02-08 |
2005-08-16 |
Wyeth Corp |
Modified and stabilized GDF propeptides and uses thereof
|
|
US20040132675A1
(en)
|
2002-02-08 |
2004-07-08 |
Calvin Kuo |
Method for treating cancer and increasing hematocrit levels
|
|
US7294472B2
(en)
|
2001-03-14 |
2007-11-13 |
Caden Biosciences |
Method for identifying modulators of G protein coupled receptor signaling
|
|
US20040121008A1
(en)
|
2001-03-16 |
2004-06-24 |
Keiko Shiraishi |
Process for producing sustained release preparation
|
|
MEP21708A
(en)
|
2001-05-24 |
2010-06-10 |
Zymogenetics Inc |
Taci-immunoglobulin fusion proteins
|
|
IL159015A0
(en)
|
2001-05-25 |
2004-05-12 |
Genset Sa |
Polypeptides, their preparation and use
|
|
AUPR638101A0
(en)
|
2001-07-13 |
2001-08-09 |
Bioa Pty Limited |
Composition and method for treatment of disease
|
|
US6855344B2
(en)
*
|
2001-07-17 |
2005-02-15 |
Integrated Chinese Medicine Holdings, Ltd. |
Compositions and methods for prostate and kidney health and disorders, an herbal preparation
|
|
CN100419425C
(zh)
|
2001-07-17 |
2008-09-17 |
帝人株式会社 |
通过测定PPARδ激活作用筛选物质的方法和药剂
|
|
KR100453877B1
(ko)
|
2001-07-26 |
2004-10-20 |
메덱스젠 주식회사 |
연쇄체화에 의한 면역 글로블린 융합 단백질의 제조 방법 및 이 방법에 의해 제조된 ＴＮＦＲ/Ｆｃ 융합 단백질, 상기 단백질을 코딩하는 ＤＮＡ, 상기 ＤＮＡ를 포함하는벡터, 및 상기 벡터에 의한 형질전환체
|
|
US7320789B2
(en)
*
|
2001-09-26 |
2008-01-22 |
Wyeth |
Antibody inhibitors of GDF-8 and uses thereof
|
|
US6784154B2
(en)
*
|
2001-11-01 |
2004-08-31 |
University Of Utah Research Foundation |
Method of use of erythropoietin to treat ischemic acute renal failure
|
|
ES2686625T3
(es)
|
2001-12-06 |
2018-10-18 |
Fibrogen, Inc. |
Métodos para el tratamiento o prevención de la anemia
|
|
US20030144203A1
(en)
|
2001-12-19 |
2003-07-31 |
Voyager Pharmaceutical Corporation |
Methods for slowing senescence and treating and preventing diseases associated with senescence
|
|
US20060234918A1
(en)
|
2001-12-19 |
2006-10-19 |
Voyager Pharmaceutical Corporation |
Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors
|
|
US6998118B2
(en)
|
2001-12-21 |
2006-02-14 |
The Salk Institute For Biological Studies |
Targeted retrograde gene delivery for neuronal protection
|
|
US20030224397A1
(en)
|
2002-02-11 |
2003-12-04 |
Genentech, Inc. |
Antibody variants with faster antigen association rates
|
|
JP4429729B2
(ja)
*
|
2002-02-21 |
2010-03-10 |
ワイス エルエルシー |
Ｇａｓｐ１；フォリスタチンドメイン含有タンパク質
|
|
US20030219846A1
(en)
|
2002-02-28 |
2003-11-27 |
Pfizer Inc. |
Assay for activity of the ActRIIB kinase
|
|
WO2003087162A2
(en)
|
2002-04-18 |
2003-10-23 |
Mtm Laboratories Ag |
Neopeptides and methods useful for detection and treatment of cancer
|
|
DE10234192B4
(de)
|
2002-07-26 |
2009-11-26 |
Epoplus Gmbh Co.Kg |
Verwendung von Erythropoetin
|
|
RU2005107330A
(ru)
|
2002-08-16 |
2005-10-10 |
Уайт (Us) |
Эстроген-чувствительный элемент вмр-2 и способы его применения
|
|
AU2003228509B2
(en)
|
2002-10-15 |
2008-06-26 |
Celgene Corporation |
Selective cytokine inhibitory drugs for treating myelodysplastic syndrome
|
|
AR047392A1
(es)
*
|
2002-10-22 |
2006-01-18 |
Wyeth Corp |
Neutralizacion de anticuerpos contra gdf 8 y su uso para tales fines
|
|
US20040223966A1
(en)
|
2002-10-25 |
2004-11-11 |
Wolfman Neil M. |
ActRIIB fusion polypeptides and uses therefor
|
|
AU2002953327A0
(en)
|
2002-12-12 |
2003-01-09 |
Monash University |
Methods of diagnosing prognosing and treating activin associated diseases and conditions
|
|
WO2004069237A1
(en)
|
2003-02-07 |
2004-08-19 |
Prometic Biosciences Inc. |
Medium-chain length fatty acids, glycerides and analogues as stimulators of erythropoiesis
|
|
US20070155661A1
(en)
|
2003-02-14 |
2007-07-05 |
The Board Of Trustees Of The Leland Standord Junior University |
Methods and compositions for modulating the development of stem cells
|
|
GB0304424D0
(en)
|
2003-02-26 |
2003-04-02 |
Glaxosmithkline Biolog Sa |
Novel compounds
|
|
WO2004086953A2
(en)
|
2003-03-26 |
2004-10-14 |
The Board Of Trustees Of The University Of Arkansas |
Method for diagnosis and treatment of bone turnover
|
|
WO2005028517A2
(en)
|
2003-05-09 |
2005-03-31 |
The General Hospital Corporation |
SOLUBLE TGF-β TYPE III RECEPTOR FUSION PROTEINS
|
|
JP5110877B2
(ja)
|
2003-06-02 |
2012-12-26 |
ワイス・エルエルシー |
神経筋障害を処置するための、コルチコステロイドと組み合わせたミオスタチン（ｇｄｆ８）インヒビターの使用
|
|
RS20050934A
(sr)
|
2003-06-16 |
2008-04-04 |
Celltech R. & D. Inc., |
Antitela specifična za sklerostin i metode za povećanje mineralizacije kostiju
|
|
WO2005009460A2
(en)
|
2003-07-25 |
2005-02-03 |
Medexis, S.A. |
Pharmaceutical composition comprising activin a, alk-4 or derivatives thereof for the treatment of ophthalmic disorders or cancer
|
|
US8895540B2
(en)
|
2003-11-26 |
2014-11-25 |
DePuy Synthes Products, LLC |
Local intraosseous administration of bone forming agents and anti-resorptive agents, and devices therefor
|
|
ES2330860T3
(es)
|
2004-01-22 |
2009-12-16 |
Merck Patent Gmbh |
Anticuerpos anticancerosos con fijacion del complemento reducida.
|
|
US20050197292A1
(en)
|
2004-01-30 |
2005-09-08 |
Glennda Smithson |
Compositions and methods for treating T-cell mediated pathological conditions
|
|
EP1732589A2
(en)
|
2004-03-26 |
2006-12-20 |
Acceleron Pharma Inc. |
Bmp-3 propeptides and related methods
|
|
AU2005230854A1
(en)
|
2004-03-31 |
2005-10-20 |
Xencor, Inc |
BMP-7 variants with improved properties
|
|
WO2005113590A2
(en)
|
2004-05-12 |
2005-12-01 |
Acceleron Pharma Inc. |
Bmp10 propeptides and related methods
|
|
US7465706B2
(en)
|
2004-06-24 |
2008-12-16 |
Acceleron Pharma Inc. |
GDF3 propeptides and related methods
|
|
EP1771470B1
(en)
|
2004-07-23 |
2013-06-26 |
Acceleron Pharma Inc. |
Actrii receptor polypeptides, methods and compositions
|
|
EP1789391B1
(en)
|
2004-07-23 |
2017-06-28 |
Endocyte, Inc. |
Bivalent linkers and conjugates thereof
|
|
EP1794191B1
(en)
|
2004-08-05 |
2016-05-18 |
The Regents of The University of California |
Molecules with effects on cellular development and function
|
|
EP1778275A2
(en)
|
2004-08-12 |
2007-05-02 |
Wyeth |
Combination therapy for diabetes, obesity, and cardiovascular diseases using gdf-8 inhibitors
|
|
US7095608B2
(en)
|
2004-08-12 |
2006-08-22 |
Audiovox Corporation |
Video display mounting system and method
|
|
CA2581896C
(en)
|
2004-09-29 |
2015-11-10 |
Mount Sinai School Of Medicine Of New York University |
Fsh and fsh receptor modulator compositions and methods for inhibiting osteoclastic bone resorption and bone loss in osteoporosis
|
|
BRPI0518728A2
(pt)
|
2004-12-09 |
2008-12-02 |
Univ Pittsburgh |
vacinas para a resposta rÁpida À pandemia de gripe aviÁria
|
|
NZ538097A
(en)
|
2005-02-07 |
2006-07-28 |
Ovita Ltd |
Method and compositions for improving wound healing
|
|
WO2006088972A2
(en)
|
2005-02-16 |
2006-08-24 |
The General Hospital Corporation |
Use of modulatirs of compounds of tgf-beta superfamily to regulate hepcidin-mediated iron metabolism
|
|
CN101198321A
(zh)
|
2005-04-26 |
2008-06-11 |
味之素株式会社 |
骨髓祖红细胞分化诱导剂
|
|
JP2007099764A
(ja)
|
2005-09-09 |
2007-04-19 |
Ajinomoto Co Inc |
血糖低下剤
|
|
DK1931697T3
(da)
|
2005-09-28 |
2010-11-08 |
Zymogenetics Inc |
IL-17A og IL-17F-antagonister og fremgangsmåder til anvendelse af disse
|
|
CA2623531C
(en)
|
2005-10-07 |
2013-12-10 |
Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa |
Matrix metalloproteinase 11 vaccine
|
|
US8067562B2
(en)
|
2005-11-01 |
2011-11-29 |
Amgen Inc. |
Isolated nucleic acid molecule comprising the amino acid sequence of SEQ ID NO:1
|
|
US8128933B2
(en)
|
2005-11-23 |
2012-03-06 |
Acceleron Pharma, Inc. |
Method of promoting bone growth by an anti-activin B antibody
|
|
US7612041B2
(en)
*
|
2005-11-23 |
2009-11-03 |
Acceleron Pharma Inc. |
Isolated activin-binding ActRIIa polypeptide comprising the SEQ ID NO: 7 and uses for promoting bone growth
|
|
MX2008007324A
(es)
|
2005-12-06 |
2009-03-04 |
Amgen Inc |
Usos de antagonistas de miostatina.
|
|
WO2007071023A1
(en)
|
2005-12-20 |
2007-06-28 |
Merck Frosst Canada Ltd. |
Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
|
|
US20070161578A1
(en)
|
2005-12-21 |
2007-07-12 |
Hwa Joyce J |
Treatment of nonalcoholic fatty liver disease using cholesterol lowering agents and/or H3 receptor antagonist/inverse agonist
|
|
WO2007076127A2
(en)
|
2005-12-22 |
2007-07-05 |
Biogen Idec Ma Inc |
Condensed imidazoles or pyrazoles and their use as transforming growth factor modulators
|
|
WO2007084976A2
(en)
*
|
2006-01-20 |
2007-07-26 |
Beckman Coulter, Inc. |
Methods of detection of iron deficiency
|
|
JP2009531280A
(ja)
|
2006-01-25 |
2009-09-03 |
ウェルスタット セラピューティクス コーポレイション |
代謝障害を処置するための化合物
|
|
AU2007220868B2
(en)
|
2006-02-28 |
2011-06-09 |
Wellstat Therapeutics Corporation |
Compounds for the treatment of metabolic disorders
|
|
CA2650131A1
(en)
|
2006-04-14 |
2007-10-25 |
Amgen Inc. |
Agonist erythropoietin receptor antibodies
|
|
WO2007123391A1
(en)
|
2006-04-20 |
2007-11-01 |
Academisch Ziekenhuis Leiden |
Therapeutic intervention in a genetic disease in an individual by modifying expression of an aberrantly expressed gene.
|
|
US20080075692A1
(en)
*
|
2006-05-09 |
2008-03-27 |
Perrine Susan P |
Methods for treating blood disorders
|
|
EP2048948B1
(en)
*
|
2006-07-21 |
2012-02-29 |
Lyne Laboratories, Inc. |
Liquid compositions of calcium acetate
|
|
GB0615129D0
(en)
|
2006-07-29 |
2006-09-06 |
Univ Cardiff |
Anti-cancer activity of BMP-9 and BMP-10 and their use in cancer therapies
|
|
CL2007002567A1
(es)
|
2006-09-08 |
2008-02-01 |
Amgen Inc |
Proteinas aisladas de enlace a activina a humana.
|
|
US7547781B2
(en)
*
|
2006-09-11 |
2009-06-16 |
Curis, Inc. |
Quinazoline based EGFR inhibitors containing a zinc binding moiety
|
|
WO2008060139A1
(en)
|
2006-11-17 |
2008-05-22 |
Erasmus University Medical Center Rotterdam |
Methods for controlling mineralization of extracellular matrix, therapeutic methods based thereon and medicaments for use therein
|
|
WO2008073292A2
(en)
|
2006-12-08 |
2008-06-19 |
Caritas St. Elizabeth's Medical Center Of Boston, Inc. |
Method for protecting renal tubular epithelial cells from radiocontrast nephro parhy (rcn)
|
|
JP5632582B2
(ja)
|
2006-12-14 |
2014-11-26 |
中外製薬株式会社 |
抗Ｃｌａｕｄｉｎ３モノクローナル抗体およびそれを用いる癌の治療および診断
|
|
EP2468290B1
(en)
|
2006-12-18 |
2015-04-01 |
Acceleron Pharma, Inc. |
Activin-ActRII Antagonists for use in treating anemia
|
|
US8895016B2
(en)
|
2006-12-18 |
2014-11-25 |
Acceleron Pharma, Inc. |
Antagonists of activin-actriia and uses for increasing red blood cell levels
|
|
US20100028332A1
(en)
|
2006-12-18 |
2010-02-04 |
Acceleron Pharma Inc. |
Antagonists of actriib and uses for increasing red blood cell levels
|
|
CN101835485B
(zh)
*
|
2007-02-01 |
2016-10-26 |
阿塞勒隆制药公司 |
活化素-actriia拮抗剂及在治疗或预防乳腺癌中的用途
|
|
TWI782836B
(zh)
|
2007-02-02 |
2022-11-01 |
美商艾瑟勒朗法瑪公司 |
衍生自ActRIIB的變體與其用途
|
|
KR101672156B1
(ko)
|
2007-02-09 |
2016-11-02 |
악셀레론 파마 인코포레이티드 |
액티빈-ＡｃｔＲⅡＡ 길항제 및 암 환자에서 골 생장을 촉진시키기 위한 이의 용도
|
|
US8501678B2
(en)
|
2007-03-06 |
2013-08-06 |
Atara Biotherapeutics, Inc. |
Variant activin receptor polypeptides and uses thereof
|
|
WO2013106175A1
(en)
|
2011-12-19 |
2013-07-18 |
Amgen Inc. |
Variant activin receptor polypeptides, alone or in combination with chemotherapy, and uses thereof
|
|
US7947646B2
(en)
|
2007-03-06 |
2011-05-24 |
Amgen Inc. |
Variant activin receptor polypeptides
|
|
JP2010529041A
(ja)
|
2007-06-01 |
2010-08-26 |
ワイス・エルエルシー |
Ｂｍｐ−１０活性を調整する方法および組成物
|
|
WO2009009059A1
(en)
|
2007-07-09 |
2009-01-15 |
Biogen Idec Ma Inc. |
Spiro compounds as antagonists of tgf-beta
|
|
GB0715087D0
(en)
|
2007-08-03 |
2007-09-12 |
Summit Corp Plc |
Drug combinations for the treatment of duchenne muscular dystrophy
|
|
SI2170396T1
(sl)
|
2007-08-03 |
2017-04-26 |
Summit (Oxford) Limited |
Kombinacije zdravil za zdravljenje duchennove mišične distrofije
|
|
GB0715938D0
(en)
|
2007-08-15 |
2007-09-26 |
Vastox Plc |
Method of treatment of duchenne muscular dystrophy
|
|
WO2009025651A1
(en)
|
2007-08-17 |
2009-02-26 |
University Of Maine System Board Of Trustees |
Biologically active peptide and method of using the same
|
|
US20100279409A1
(en)
|
2007-09-13 |
2010-11-04 |
Neil Robson |
Method for modifying celluar immune resonse by modulating activin activity
|
|
WO2009038745A1
(en)
|
2007-09-18 |
2009-03-26 |
Acceleron Pharma Inc. |
Activin-actriia antagonists and uses for decreasing or inhibiting fsh secretion
|
|
PE20091163A1
(es)
*
|
2007-11-01 |
2009-08-09 |
Wyeth Corp |
Anticuerpos para gdf8
|
|
US8043620B2
(en)
|
2007-11-21 |
2011-10-25 |
Amgen Inc. |
Wise binding agents and epitopes
|
|
JP5638961B2
(ja)
|
2008-03-13 |
2014-12-10 |
ザ ジェネラル ホスピタル コーポレイション |
Ｂｍｐシグナル伝達経路のインヒビター
|
|
EP2283119B1
(en)
|
2008-05-06 |
2015-01-07 |
Joslin Diabetes Center, Inc. |
Methods and compositions for inducing brown adipogenesis
|
|
WO2009137075A1
(en)
|
2008-05-06 |
2009-11-12 |
Acceleron Pharma Inc. |
Anti-activin antibodies and uses for promoting bone growth
|
|
JP5773868B2
(ja)
*
|
2008-06-26 |
2015-09-02 |
アクセルロン ファーマ， インコーポレイテッド |
アクチビン−ＡｃｔＲＩＩａのアンタゴニストおよび赤血球レベルを高めるためのその使用
|
|
US20100015144A1
(en)
|
2008-06-26 |
2010-01-21 |
Acceleron Pharma Inc. |
Methods for dosing an activin-actriia antagonist and monitoring of treated patients
|
|
US8058229B2
(en)
|
2008-08-14 |
2011-11-15 |
Acceleron Pharma Inc. |
Method of increasing red blood cell levels or treating anemia in a patient
|
|
US8216997B2
(en)
|
2008-08-14 |
2012-07-10 |
Acceleron Pharma, Inc. |
Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
|
|
WO2010059861A1
(en)
|
2008-11-20 |
2010-05-27 |
University Of Southern California |
Compositions and methods to modulate hair growth
|
|
MY159483A
(en)
|
2008-11-26 |
2017-01-13 |
Amgen Inc |
Variants of activin iib receptor polypeptides and uses thereof
|
|
AU2010204985A1
(en)
|
2009-01-13 |
2011-08-04 |
Acceleron Pharma Inc. |
Methods for increasing adiponectin
|
|
US8110355B2
(en)
|
2009-02-20 |
2012-02-07 |
GenRemedy, LLC |
Methods for identifying agents that inhibit cell migration, promote cell adhesion and prevent metastasis
|
|
HUE035240T2
(hu)
|
2009-04-27 |
2018-05-02 |
Novartis Ag |
Készítmények és eljárások az izomerõ növelésére
|
|
CN102482339B
(zh)
|
2009-06-08 |
2015-06-17 |
阿塞勒隆制药公司 |
用于增加产热脂肪细胞的方法
|
|
CN107267520A
(zh)
|
2009-06-12 |
2017-10-20 |
阿塞勒隆制药公司 |
截短的actriib‑fc融合蛋白
|
|
CN113171442B
(zh)
|
2009-08-13 |
2024-11-15 |
阿塞勒隆制药公司 |
Gdf捕获物和促红细胞生成素受体激活剂联合应用以增加红细胞水平
|
|
MX340451B
(es)
|
2009-09-09 |
2016-07-08 |
Acceleron Pharma Inc |
Antagonistas de actriib y dosificacion y usos de los mismos.
|
|
JP5836961B2
(ja)
|
2009-11-03 |
2015-12-24 |
アクセルロン ファーマ， インコーポレイテッド |
脂肪肝疾患を処置するための方法
|
|
US8710016B2
(en)
|
2009-11-17 |
2014-04-29 |
Acceleron Pharma, Inc. |
ActRIIB proteins and variants and uses therefore relating to utrophin induction for muscular dystrophy therapy
|
|
WO2012027065A2
(en)
|
2010-08-27 |
2012-03-01 |
Celgene Corporation |
Combination therapy for treatment of disease
|
|
US9595813B2
(en)
|
2011-01-24 |
2017-03-14 |
Soraa Laser Diode, Inc. |
Laser package having multiple emitters configured on a substrate member
|
|
US8580922B2
(en)
|
2011-03-04 |
2013-11-12 |
Shire Human Genetic Therapies, Inc. |
Peptide linkers for polypeptide compositions and methods for using same
|
|
WO2013006437A1
(en)
|
2011-07-01 |
2013-01-10 |
Novartis Ag |
Method for treating metabolic disorders
|
|
DK3520805T3
(da)
|
2011-10-17 |
2021-04-19 |
Acceleron Pharma Inc |
Sammensætninger til behandling af myelofibrose
|
|
US8765385B2
(en)
|
2011-10-27 |
2014-07-01 |
Ravindra Kumar |
Method of detection of neutralizing anti-actriib antibodies
|
|
WO2013063536A1
(en)
|
2011-10-27 |
2013-05-02 |
Acceleron Pharma, Inc. |
Actriib binding agents and uses thereof
|
|
WO2013059876A1
(en)
|
2011-10-28 |
2013-05-02 |
Paranta Biosciences Limited |
A method of treating mucus hypersecretion
|
|
US10501512B2
(en)
|
2012-04-02 |
2019-12-10 |
Modernatx, Inc. |
Modified polynucleotides
|
|
WO2013186777A2
(en)
|
2012-06-14 |
2013-12-19 |
The Medical Researth, Infrastructure, And Health Services Fund Of The Tel Aviv Medical Center |
Use of blocking agents of bone morphogenie protein (bmp) signaling for the treatment of neuroinflammatory and neurodegenerative diseases
|
|
CA2874117C
(en)
|
2012-07-02 |
2021-10-12 |
Kyowa Hakko Kirin Co., Ltd. |
Pharmaceutical agent comprising anti-bmp9 antibody as active ingredient for treatment of anemia such as renal anemia and cancer anemia
|
|
US20150266950A1
(en)
|
2012-10-24 |
2015-09-24 |
Celgene Corporation |
Methods for treating anemia
|
|
WO2014066486A2
(en)
|
2012-10-24 |
2014-05-01 |
Celgene Corporation |
Biomarker for use in treating anemia
|
|
WO2014064292A1
(en)
|
2012-10-26 |
2014-05-01 |
Universite Pierre Et Marie Curie (Paris 6) |
A method for preventing or treating atrial fibrillation
|
|
AU2013337677B2
(en)
|
2012-11-02 |
2018-06-28 |
Celgene Corporation |
Activin-ActRII antagonists and uses for treating bone and other disorders
|
|
CN110893188A
(zh)
|
2012-11-08 |
2020-03-20 |
克莱尔塞德生物医学股份有限公司 |
用于在人类受试者中治疗眼部疾病的方法和装置
|
|
US20150328249A1
(en)
|
2012-12-11 |
2015-11-19 |
Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center |
Modulation of myofiber repair by anti-myostatin strategies and/or ppar gamma ligands, alone or in combination with stem cells, for the therapy of critical limb ischemia and other ischemic processes affecting the skeletal muscle
|
|
US20140220033A1
(en)
|
2013-02-01 |
2014-08-07 |
Santa Maria Biotherapeutics, Inc. |
Administration of an Anti-Activin-A Compound to a Subject
|
|
EP3431592A1
(en)
|
2013-03-14 |
2019-01-23 |
Translate Bio, Inc. |
Mrna therapeutic compositions and use to treat diseases and disorders
|
|
TW201920262A
(zh)
|
2013-07-30 |
2019-06-01 |
美商再生元醫藥公司 |
抗活化素ａ之抗體及其用途
|
|
US20160200818A1
(en)
|
2013-08-14 |
2016-07-14 |
Novartis Ag |
Methods of treating Sporadic Inclusion Body Myositis
|
|
WO2015089575A1
(en)
|
2013-12-16 |
2015-06-25 |
Paranta Biosciences Limited |
Method of diagnosis and treatment
|
|
EP3094751A4
(en)
|
2014-01-14 |
2017-06-07 |
Santa Maria Biotherapeutics, Inc. |
Activin inhibitor response prediction and uses for treatment
|
|
EP3100056A2
(en)
|
2014-01-27 |
2016-12-07 |
Novartis AG |
Biomarkers predictive of muscle atrophy, method and use
|
|
WO2015152183A1
(ja)
|
2014-03-31 |
2015-10-08 |
大日本住友製薬株式会社 |
進行性骨化性線維異形成症の予防剤及び治療剤
|
|
EP3131931B1
(en)
|
2014-04-18 |
2020-10-21 |
Acceleron Pharma Inc. |
Methods for increasing red blood cell levels and treating sickle-cell disease
|
|
TW201622746A
(zh)
|
2014-04-24 |
2016-07-01 |
諾華公司 |
改善或加速髖部骨折術後身體復原之方法
|
|
BR122023023170A2
(pt)
|
2014-06-13 |
2024-02-20 |
Acceleron Pharma Inc. |
Uso de um antagonista de actrii no tratamento ou prevenção de úlcera cutânea associada com beta-talassemia
|
|
CA2952231A1
(en)
|
2014-06-13 |
2015-12-17 |
Santa Maria Biotherapeutics, Inc. |
Formulated receptor polypeptides and related methods
|
|
TN2017000468A1
(en)
|
2015-05-13 |
2019-04-12 |
Acceleron Pharma Inc |
TREATMENT OF BETA-THALASSEMIA USING ACTRIl LIGAND TRAPS.
|