SMT201400133B - Composti e composizioni come inibitori di protein chinasi - Google Patents

Composti e composizioni come inibitori di protein chinasi

Info

Publication number
SMT201400133B
SMT201400133B SM201400133T SM201400133T SMT201400133B SM T201400133 B SMT201400133 B SM T201400133B SM 201400133 T SM201400133 T SM 201400133T SM 201400133 T SM201400133 T SM 201400133T SM T201400133 B SMT201400133 B SM T201400133B
Authority
SM
San Marino
Prior art keywords
compositions
compounds
protein kinase
kinase inhibitors
inhibitors
Prior art date
Application number
SM201400133T
Other languages
English (en)
Italian (it)
Inventor
Daniel Poon
Yongqin Wan
Shenlin Huang
Zuosheng Liu
Xing Wang
Yongping Xie
John TELLEW
Xianming Jin
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42782253&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SMT201400133(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SMT201400133B publication Critical patent/SMT201400133B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Otolaryngology (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
SM201400133T 2009-08-28 2014-09-12 Composti e composizioni come inibitori di protein chinasi SMT201400133B (it)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US23807309P 2009-08-28 2009-08-28
US31303910P 2010-03-11 2010-03-11
PCT/US2010/046930 WO2011025927A1 (fr) 2009-08-28 2010-08-27 Composés et compositions en tant qu'inhibiteurs de protéine kinase

Publications (1)

Publication Number Publication Date
SMT201400133B true SMT201400133B (it) 2014-11-10

Family

ID=42782253

Family Applications (2)

Application Number Title Priority Date Filing Date
SM201400133T SMT201400133B (it) 2009-08-28 2014-09-12 Composti e composizioni come inibitori di protein chinasi
SM201700036T SMT201700036B (it) 2009-08-28 2017-01-19 Composti e composizioni come inibitori di protein chinasi

Family Applications After (1)

Application Number Title Priority Date Filing Date
SM201700036T SMT201700036B (it) 2009-08-28 2017-01-19 Composti e composizioni come inibitori di protein chinasi

Country Status (50)

Country Link
US (12) US8501758B2 (fr)
EP (2) EP2727918B1 (fr)
JP (2) JP5475888B2 (fr)
KR (1) KR101413392B1 (fr)
CN (2) CN103896921B (fr)
AR (1) AR077975A1 (fr)
AU (1) AU2010286569C1 (fr)
BR (1) BR112012004453B1 (fr)
CA (1) CA2771775C (fr)
CL (1) CL2012000340A1 (fr)
CO (1) CO6612222A2 (fr)
CR (1) CR20120102A (fr)
CU (1) CU24110B1 (fr)
CY (3) CY1118452T1 (fr)
DK (2) DK2727918T3 (fr)
DO (1) DOP2012000051A (fr)
EA (2) EA201500175A1 (fr)
EC (2) ECSP12011700A (fr)
ES (2) ES2610825T3 (fr)
GE (1) GEP20146102B (fr)
GT (1) GT201200053A (fr)
HK (1) HK1167390A1 (fr)
HN (1) HN2012000441A (fr)
HR (2) HRP20140799T1 (fr)
HU (3) HUE032847T2 (fr)
IL (1) IL218084A (fr)
IN (1) IN2012DN02469A (fr)
JO (1) JO3002B1 (fr)
LT (3) LT2727918T (fr)
LU (2) LUC00101I2 (fr)
MA (1) MA33604B1 (fr)
ME (2) ME02684B (fr)
MX (1) MX2012002546A (fr)
MY (1) MY156259A (fr)
NI (1) NI201200029A (fr)
NL (1) NL300973I2 (fr)
NO (1) NO2019011I1 (fr)
NZ (1) NZ598924A (fr)
PE (1) PE20120861A1 (fr)
PL (2) PL2470526T3 (fr)
PT (2) PT2727918T (fr)
RS (2) RS53489B1 (fr)
SG (2) SG10201405311TA (fr)
SI (2) SI2470526T1 (fr)
SM (2) SMT201400133B (fr)
TN (1) TN2012000081A1 (fr)
UA (1) UA112285C2 (fr)
UY (1) UY32860A (fr)
WO (1) WO2011025927A1 (fr)
ZA (1) ZA201202020B (fr)

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