US20160120866A1 - Compounds and compositions as protein kinase inhibitors - Google Patents

Compounds and compositions as protein kinase inhibitors Download PDF

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Publication number
US20160120866A1
US20160120866A1 US14/994,827 US201614994827A US2016120866A1 US 20160120866 A1 US20160120866 A1 US 20160120866A1 US 201614994827 A US201614994827 A US 201614994827A US 2016120866 A1 US2016120866 A1 US 2016120866A1
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United States
Prior art keywords
yl
1h
propan
pyrazol
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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US14/994,827
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US9593100B2 (en
Inventor
Shenlin Huang
Xianming Jin
Zuosheng Liu
Daniel Poon
John Tellew
Yongqin Wan
Xing Wang
Yongping Xie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Array Biopharma Inc
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Novartis AG
Array Biopharma Inc
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Priority to US23807309P priority Critical
Priority to US31303910P priority
Priority to US12/870,130 priority patent/US8501758B2/en
Priority to US13/931,111 priority patent/US9314464B2/en
Priority to US14/994,827 priority patent/US9593100B2/en
Application filed by Novartis AG, Array Biopharma Inc filed Critical Novartis AG
Publication of US20160120866A1 publication Critical patent/US20160120866A1/en
Assigned to IRM LLC reassignment IRM LLC ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: WANG, XING, XIE, YONGPING, WAN, YONGQIN, HUANG, SHENLIN, LIU, ZUOSHENG, TELLEW, JOHN
Assigned to ARRAY BIOPHARMA, INC. reassignment ARRAY BIOPHARMA, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: NOVARTIS AG
Assigned to NOVARTIS AG reassignment NOVARTIS AG ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: JIN, XIANMING, POON, DANIEL
Assigned to NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. reassignment NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. MERGER (SEE DOCUMENT FOR DETAILS). Assignors: IRM LLC
Assigned to NOVARTIS AG reassignment NOVARTIS AG ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD.
Publication of US9593100B2 publication Critical patent/US9593100B2/en
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Application status is Active legal-status Critical
Anticipated expiration legal-status Critical

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