BRPI0914652A2 - compostos e composições como inibidores de quinase - Google Patents

compostos e composições como inibidores de quinase

Info

Publication number
BRPI0914652A2
BRPI0914652A2 BRPI0914652A BRPI0914652A BRPI0914652A2 BR PI0914652 A2 BRPI0914652 A2 BR PI0914652A2 BR PI0914652 A BRPI0914652 A BR PI0914652A BR PI0914652 A BRPI0914652 A BR PI0914652A BR PI0914652 A2 BRPI0914652 A2 BR PI0914652A2
Authority
BR
Brazil
Prior art keywords
compositions
compounds
kinase inhibitors
kinase
inhibitors
Prior art date
Application number
BRPI0914652A
Other languages
English (en)
Inventor
Chen Bei
Cho-Hua Lee Christian
Yang Kunyong
Jiang Songchun
H Marsilje Thomas Iii
Lu Wenshuo
He Xiaohui
Original Assignee
Irm Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irm Llc filed Critical Irm Llc
Publication of BRPI0914652A2 publication Critical patent/BRPI0914652A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
BRPI0914652A 2008-06-25 2009-06-24 compostos e composições como inibidores de quinase BRPI0914652A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7558308P 2008-06-25 2008-06-25
US15543409P 2009-02-25 2009-02-25
PCT/US2009/048428 WO2010002655A2 (en) 2008-06-25 2009-06-24 Compounds and compositions as kinase inhibitors

Publications (1)

Publication Number Publication Date
BRPI0914652A2 true BRPI0914652A2 (pt) 2017-06-06

Family

ID=41349515

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0914652A BRPI0914652A2 (pt) 2008-06-25 2009-06-24 compostos e composições como inibidores de quinase

Country Status (29)

Country Link
US (2) US8519129B2 (pt)
EP (1) EP2318392A2 (pt)
JP (1) JP5508412B2 (pt)
KR (1) KR101432352B1 (pt)
CN (1) CN102112467B (pt)
AR (1) AR072787A1 (pt)
AU (1) AU2009264934B2 (pt)
BR (1) BRPI0914652A2 (pt)
CA (1) CA2729495C (pt)
CL (1) CL2009001476A1 (pt)
CO (1) CO6351787A2 (pt)
CR (1) CR20110028A (pt)
DO (1) DOP2010000397A (pt)
EA (1) EA020730B1 (pt)
EC (1) ECSP11010784A (pt)
GE (1) GEP20125564B (pt)
HN (1) HN2010002733A (pt)
IL (1) IL210124A0 (pt)
MA (1) MA32497B1 (pt)
MX (1) MX2010014039A (pt)
NI (1) NI201000219A (pt)
NZ (1) NZ590602A (pt)
PA (1) PA8834001A1 (pt)
PE (1) PE20100087A1 (pt)
SV (1) SV2010003776A (pt)
TW (1) TW201000466A (pt)
UY (1) UY31929A (pt)
WO (1) WO2010002655A2 (pt)
ZA (1) ZA201100344B (pt)

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Also Published As

Publication number Publication date
PE20100087A1 (es) 2010-02-08
CR20110028A (es) 2011-04-07
NZ590602A (en) 2011-10-28
KR101432352B1 (ko) 2014-08-21
US20130310361A1 (en) 2013-11-21
CL2009001476A1 (es) 2010-01-11
DOP2010000397A (es) 2011-01-15
CN102112467B (zh) 2014-04-30
ZA201100344B (en) 2012-10-31
WO2010002655A3 (en) 2010-04-01
US20110112063A1 (en) 2011-05-12
WO2010002655A2 (en) 2010-01-07
PA8834001A1 (es) 2010-04-21
IL210124A0 (en) 2011-02-28
EA201100077A1 (ru) 2011-08-30
CO6351787A2 (es) 2011-12-20
UY31929A (es) 2010-01-05
KR20110022699A (ko) 2011-03-07
MA32497B1 (fr) 2011-07-03
JP2011526284A (ja) 2011-10-06
ECSP11010784A (es) 2011-02-28
TW201000466A (en) 2010-01-01
HN2010002733A (es) 2013-01-28
CA2729495A1 (en) 2010-01-07
NI201000219A (es) 2011-05-24
MX2010014039A (es) 2011-01-21
GEP20125564B (en) 2012-06-25
AU2009264934A1 (en) 2010-01-07
AR072787A1 (es) 2010-09-22
JP5508412B2 (ja) 2014-05-28
SV2010003776A (es) 2012-01-04
EP2318392A2 (en) 2011-05-11
US8859574B2 (en) 2014-10-14
CA2729495C (en) 2013-12-17
AU2009264934B2 (en) 2012-09-27
EA020730B1 (ru) 2015-01-30
CN102112467A (zh) 2011-06-29
US8519129B2 (en) 2013-08-27

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