SK287163B6 - Pyridazinylfenylhydrazón užitočný proti kongestívnemu zlyhaniu srdca a farmaceutická kompozícia s jeho obsahom - Google Patents

Pyridazinylfenylhydrazón užitočný proti kongestívnemu zlyhaniu srdca a farmaceutická kompozícia s jeho obsahom Download PDF

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Publication number
SK287163B6
SK287163B6 SK1288-2002A SK12882002A SK287163B6 SK 287163 B6 SK287163 B6 SK 287163B6 SK 12882002 A SK12882002 A SK 12882002A SK 287163 B6 SK287163 B6 SK 287163B6
Authority
SK
Slovakia
Prior art keywords
alkyl
methyl
phenyl
aryl
pyridazin
Prior art date
Application number
SK1288-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK12882002A3 (sk
Inventor
Jarmo Pystynen
Aino Pippuri
Anne Luiro
Pentti Nore
Reijo B�CKSTR�M
Kari L�NNBERG
Heimo Haikala
Jouko Levijoki
Petri Kaheinen
Juha Kaivola
Original Assignee
Orion Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Corporation filed Critical Orion Corporation
Publication of SK12882002A3 publication Critical patent/SK12882002A3/sk
Publication of SK287163B6 publication Critical patent/SK287163B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SK1288-2002A 2000-03-13 2001-03-12 Pyridazinylfenylhydrazón užitočný proti kongestívnemu zlyhaniu srdca a farmaceutická kompozícia s jeho obsahom SK287163B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20000577A FI20000577A0 (fi) 2000-03-13 2000-03-13 Pyridatsinyylifenyylihydratsoneja
PCT/FI2001/000241 WO2001068611A1 (en) 2000-03-13 2001-03-12 Pyridazinyl phenyl hydrazones useful against congestive heart failure

Publications (2)

Publication Number Publication Date
SK12882002A3 SK12882002A3 (sk) 2003-06-03
SK287163B6 true SK287163B6 (sk) 2010-02-08

Family

ID=8557913

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1288-2002A SK287163B6 (sk) 2000-03-13 2001-03-12 Pyridazinylfenylhydrazón užitočný proti kongestívnemu zlyhaniu srdca a farmaceutická kompozícia s jeho obsahom

Country Status (32)

Country Link
US (1) US6699868B2 (de)
EP (1) EP1265871B1 (de)
JP (1) JP2003527375A (de)
KR (1) KR20030001379A (de)
CN (1) CN1191241C (de)
AR (1) AR027644A1 (de)
AT (1) ATE317388T1 (de)
AU (2) AU4657701A (de)
BG (1) BG65859B1 (de)
BR (1) BR0109136A (de)
CA (1) CA2403188A1 (de)
CZ (1) CZ20022997A3 (de)
DE (1) DE60117131T2 (de)
DK (1) DK1265871T3 (de)
EA (1) EA005574B1 (de)
EE (1) EE200200520A (de)
ES (1) ES2256222T3 (de)
FI (1) FI20000577A0 (de)
HK (1) HK1052008A1 (de)
HR (1) HRP20020816A2 (de)
HU (1) HUP0300177A3 (de)
IL (2) IL151492A0 (de)
MX (1) MXPA02008997A (de)
NO (1) NO324172B1 (de)
NZ (1) NZ521162A (de)
PL (1) PL357107A1 (de)
RS (1) RS50439B (de)
SI (1) SI1265871T1 (de)
SK (1) SK287163B6 (de)
UA (1) UA74571C2 (de)
WO (1) WO2001068611A1 (de)
ZA (1) ZA200206917B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0015228D0 (en) * 2000-06-21 2000-08-16 Portela & Ca Sa Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders
JP4561698B2 (ja) * 2002-02-19 2010-10-13 小野薬品工業株式会社 縮合ピリダジン誘導体化合物およびその化合物を有効成分として含有する薬剤
EP1612204A4 (de) * 2003-03-31 2007-04-11 Daiichi Seiyaku Co Hydrazon-derivate
GB0503962D0 (en) 2005-02-25 2005-04-06 Kudos Pharm Ltd Compounds
SI2069312T1 (sl) 2006-07-25 2013-03-29 Cephalon, Inc. Derivati piridizinona
AU2008206903B2 (en) * 2007-01-17 2012-07-05 Orion Corporation Levosimendan for use in treating chronic valvular disease
CN103842334B (zh) * 2011-09-27 2016-06-29 日本瑞翁株式会社 聚合性化合物的制备中间体及其制备方法
WO2014113620A2 (en) * 2013-01-18 2014-07-24 Bristol-Myers Squibb Company Phthalazinones and isoquinolinones as rock inhibitors
US20210253518A1 (en) * 2018-06-08 2021-08-19 Nissan Chemical Corporation Kinase inhibitor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531658A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Heterocyclisch substituierte indole, zwischenprodukte, verfahren zu ihrer herstellung und arzneimittel
GB8903130D0 (en) * 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
US5185332A (en) * 1989-02-11 1993-02-09 Orion-Yhtyma Oy Thiadiazines and pharmaceutical compositions thereof as well as method of use
FI973804A (fi) * 1997-09-26 1999-03-27 Orion Yhtymae Oy Levosimendaanin oraalisia koostumuksia

Also Published As

Publication number Publication date
RS50439B (sr) 2009-12-31
EA005574B1 (ru) 2005-04-28
DE60117131T2 (de) 2006-10-26
US6699868B2 (en) 2004-03-02
EP1265871B1 (de) 2006-02-08
ATE317388T1 (de) 2006-02-15
ZA200206917B (en) 2003-07-30
AU4657701A (en) 2001-09-24
JP2003527375A (ja) 2003-09-16
ES2256222T3 (es) 2006-07-16
CZ20022997A3 (cs) 2003-04-16
HUP0300177A2 (hu) 2003-07-28
BG65859B1 (bg) 2010-03-31
EE200200520A (et) 2004-04-15
DK1265871T3 (da) 2006-06-06
MXPA02008997A (es) 2003-04-25
BR0109136A (pt) 2002-12-24
DE60117131D1 (de) 2006-04-20
EA200200973A1 (ru) 2003-02-27
US20030158200A1 (en) 2003-08-21
WO2001068611A1 (en) 2001-09-20
FI20000577A0 (fi) 2000-03-13
CN1191241C (zh) 2005-03-02
HUP0300177A3 (en) 2003-09-29
AU2001246577B2 (en) 2006-08-31
AR027644A1 (es) 2003-04-09
PL357107A1 (en) 2004-07-12
KR20030001379A (ko) 2003-01-06
IL151492A0 (en) 2003-04-10
NZ521162A (en) 2003-11-28
UA74571C2 (en) 2006-01-16
NO20024247D0 (no) 2002-09-05
NO20024247L (no) 2002-10-25
YU68502A (sh) 2005-11-28
IL151492A (en) 2007-09-20
HK1052008A1 (en) 2003-08-29
CA2403188A1 (en) 2001-09-20
EP1265871A1 (de) 2002-12-18
SI1265871T1 (sl) 2006-06-30
NO324172B1 (no) 2007-09-03
HRP20020816A2 (en) 2004-12-31
SK12882002A3 (sk) 2003-06-03
CN1418196A (zh) 2003-05-14
BG107175A (bg) 2003-05-30

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Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20110312