SK284689B6 - Benzopyrano[3,4-f]chinolínová zlúčenina a liečivo s jej obsahom - Google Patents
Benzopyrano[3,4-f]chinolínová zlúčenina a liečivo s jej obsahom Download PDFInfo
- Publication number
- SK284689B6 SK284689B6 SK1197-2000A SK11972000A SK284689B6 SK 284689 B6 SK284689 B6 SK 284689B6 SK 11972000 A SK11972000 A SK 11972000A SK 284689 B6 SK284689 B6 SK 284689B6
- Authority
- SK
- Slovakia
- Prior art keywords
- benzopyrano
- dihydro
- trimethyl
- quinoline
- methoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2394798A | 1998-02-13 | 1998-02-13 | |
| US24783199A | 1999-02-10 | 1999-02-10 | |
| PCT/US1999/003127 WO1999041256A1 (en) | 1998-02-13 | 1999-02-12 | Glucocorticoid-selective anti-inflammatory agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SK11972000A3 SK11972000A3 (sk) | 2001-08-06 |
| SK284689B6 true SK284689B6 (sk) | 2005-09-08 |
Family
ID=26697833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK1197-2000A SK284689B6 (sk) | 1998-02-13 | 1999-02-12 | Benzopyrano[3,4-f]chinolínová zlúčenina a liečivo s jej obsahom |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1053239B1 (ko) |
| JP (1) | JP2002503665A (ko) |
| KR (1) | KR20010040935A (ko) |
| CN (1) | CN1119348C (ko) |
| AT (1) | ATE230749T1 (ko) |
| AU (1) | AU766441B2 (ko) |
| BG (1) | BG64317B1 (ko) |
| BR (1) | BR9907788A (ko) |
| CA (1) | CA2320943A1 (ko) |
| DE (1) | DE69904804T2 (ko) |
| DK (1) | DK1053239T3 (ko) |
| ES (1) | ES2192035T3 (ko) |
| HK (1) | HK1033308A1 (ko) |
| HU (1) | HUP0100460A3 (ko) |
| IL (1) | IL137508A0 (ko) |
| NO (1) | NO20004053L (ko) |
| NZ (1) | NZ506013A (ko) |
| PL (1) | PL193323B1 (ko) |
| SK (1) | SK284689B6 (ko) |
| TR (1) | TR200003094T2 (ko) |
| WO (1) | WO1999041256A1 (ko) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6506766B1 (en) | 1998-02-13 | 2003-01-14 | Abbott Laboratories | Glucocortiocoid-selective antinflammatory agents |
| US6436986B1 (en) | 1999-09-01 | 2002-08-20 | Abbott Laboratories | Glucocorticoid receptor antagonists for treatment of diabetes |
| US6593480B2 (en) | 1999-09-01 | 2003-07-15 | Abbott Laboratories | Glucocorticoid receptor antagonists for treatment of diabetes |
| US6329534B1 (en) | 1999-09-01 | 2001-12-11 | Abbott Laboratories | Glucocorticoid receptor antagonists for treatment of diabetes |
| CO5180649A1 (es) * | 1999-09-01 | 2002-07-30 | Abbott Lab | Antagonistas de los receptores de los glucocorticoides para el tratamiento de la diabetes para el tratamiento de la diabetes |
| DE60113032T2 (de) | 2000-10-30 | 2006-07-06 | Pfizer Products Inc., Groton | Glukokortikoidrezeptor-Modulatoren |
| US6608216B2 (en) | 2001-06-29 | 2003-08-19 | Abbott Laboratories | Process for the preparation of chiral glucocorticoid receptor agents |
| WO2003002548A1 (en) * | 2001-06-29 | 2003-01-09 | Abbott Laboratories | A process for the preparation of chiral glucocorticoid receptor agents |
| US6518430B1 (en) | 2001-09-21 | 2003-02-11 | Abbott Laboratories | Process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-F]quinolines and derivatives thereof |
| CA2472746A1 (en) | 2002-01-14 | 2003-07-24 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations containing them and uses thereof |
| WO2003082787A1 (en) | 2002-03-26 | 2003-10-09 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| ES2298508T3 (es) | 2002-03-26 | 2008-05-16 | Boehringer Ingelheim Pharmaceuticals Inc. | Mimeticos de glucocorticoides, metodos para prepararlos, composiciones farmaceuticas y sus usos. |
| DE60335869D1 (de) | 2002-04-11 | 2011-03-10 | Merck Sharp & Dohme | 1h-benzo(f)indazol-5-yl-derivate als selektive glucocorticoid-rezeptor-modulatoren |
| US7186864B2 (en) | 2002-05-29 | 2007-03-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| US7074806B2 (en) | 2002-06-06 | 2006-07-11 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| EP1532113B1 (en) | 2002-08-21 | 2008-08-06 | Boehringer Ingelheim Pharmaceuticals Inc. | Substituted hihydroquinolines as glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| EP1558618A1 (en) | 2002-10-11 | 2005-08-03 | Ligand Pharmaceuticals, Inc. | 5-(1 ,1 -CYCLOALKYL/ALKENYL)METHYLIDENE 1,2-DIHYDRO- 5H /-CHROMENO[3,4-f ] QUINOLINES AS SELECTIVE PROGESTERONE RECEPTOR MODULATOR COMPOUNDS |
| EP1551845A1 (en) | 2002-10-11 | 2005-07-13 | Ligand Pharmaceuticals, Inc. | 5-CYCLOALKENYL 5 i H /i -CHROMENO 3,4-F QUINOLINE DERIV ATIVES AS SELECTIVE PROGESTERONE RECEPTOR MODULATOR COMPOUNDS |
| DE20301728U1 (de) | 2002-10-11 | 2004-03-11 | Ligand Pharmaceuticals, Inc., San Diego | 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen |
| WO2004063163A1 (en) | 2003-01-03 | 2004-07-29 | Boehringer Ingelheim Pharmaceuticals, Inc. | 1-propanol and 1-propylamine derivatives and their use as glucocorticoid ligands |
| US20070088042A1 (en) | 2004-09-09 | 2007-04-19 | Meissner Robert S | Fluorinated 4-azasteroid derivatives as androgen receptor modulators |
| US7235662B2 (en) | 2003-06-11 | 2007-06-26 | Bristol-Myers Squibb Company | Modulators of the glucocorticoid receptor and method |
| US8097606B2 (en) | 2003-07-23 | 2012-01-17 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of catatonia |
| UY28526A1 (es) | 2003-09-24 | 2005-04-29 | Boehringer Ingelheim Pharma | Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos |
| EP1675839B1 (en) | 2003-10-16 | 2007-07-11 | Boehringer Ingelheim Pharmaceuticals Inc. | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols |
| US7795272B2 (en) | 2004-03-13 | 2010-09-14 | Boehringer Ingelheim Pharmaceutical, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof |
| US7741361B2 (en) | 2004-12-27 | 2010-06-22 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| CA2621292C (en) * | 2005-09-14 | 2014-05-27 | Santen Pharmaceutical Co., Ltd. | 1-2-dihydroquinoline derivative having glucocorticoid receptor binding actvity |
| JP2012530140A (ja) | 2009-06-16 | 2012-11-29 | メルク・シャープ・アンド・ドーム・コーポレーション | グルココルチコイド受容体アゴニストとしての新規［３，２−ｃ］ヘテロアリールステロイド、組成物およびこの使用 |
| WO2011016050A2 (en) | 2009-07-31 | 2011-02-10 | Cadila Healthcare Limited | Novel compounds as modulators of glucocorticoid receptors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69531998T2 (de) * | 1994-12-22 | 2004-07-22 | Ligand Pharmaceuticals, Inc., San Diego | Steroidrezeptor-modulator verbindungen und methoden |
-
1999
- 1999-02-12 SK SK1197-2000A patent/SK284689B6/sk unknown
- 1999-02-12 EP EP99906996A patent/EP1053239B1/en not_active Expired - Lifetime
- 1999-02-12 JP JP2000531449A patent/JP2002503665A/ja active Pending
- 1999-02-12 AU AU26773/99A patent/AU766441B2/en not_active Ceased
- 1999-02-12 DK DK99906996T patent/DK1053239T3/da active
- 1999-02-12 KR KR1020007008850A patent/KR20010040935A/ko not_active Application Discontinuation
- 1999-02-12 BR BR9907788-4A patent/BR9907788A/pt not_active Application Discontinuation
- 1999-02-12 HU HU0100460A patent/HUP0100460A3/hu unknown
- 1999-02-12 TR TR2000/03094T patent/TR200003094T2/xx unknown
- 1999-02-12 AT AT99906996T patent/ATE230749T1/de active
- 1999-02-12 CA CA002320943A patent/CA2320943A1/en not_active Abandoned
- 1999-02-12 NZ NZ506013A patent/NZ506013A/xx unknown
- 1999-02-12 IL IL13750899A patent/IL137508A0/xx unknown
- 1999-02-12 WO PCT/US1999/003127 patent/WO1999041256A1/en active IP Right Grant
- 1999-02-12 DE DE69904804T patent/DE69904804T2/de not_active Expired - Lifetime
- 1999-02-12 CN CN99804902A patent/CN1119348C/zh not_active Expired - Fee Related
- 1999-02-12 PL PL343018A patent/PL193323B1/pl not_active IP Right Cessation
- 1999-02-12 ES ES99906996T patent/ES2192035T3/es not_active Expired - Lifetime
-
2000
- 2000-08-11 NO NO20004053A patent/NO20004053L/no not_active Application Discontinuation
- 2000-08-28 BG BG104719A patent/BG64317B1/bg unknown
-
2001
- 2001-04-19 HK HK01102793A patent/HK1033308A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE230749T1 (de) | 2003-01-15 |
| BG104719A (en) | 2001-05-31 |
| BR9907788A (pt) | 2001-10-30 |
| PL343018A1 (en) | 2001-07-30 |
| IL137508A0 (en) | 2001-07-24 |
| JP2002503665A (ja) | 2002-02-05 |
| CN1119348C (zh) | 2003-08-27 |
| NO20004053L (no) | 2000-09-11 |
| SK11972000A3 (sk) | 2001-08-06 |
| EP1053239B1 (en) | 2003-01-08 |
| HUP0100460A2 (hu) | 2001-09-28 |
| CN1296486A (zh) | 2001-05-23 |
| HUP0100460A3 (en) | 2003-03-28 |
| NZ506013A (en) | 2003-03-28 |
| DK1053239T3 (da) | 2003-04-22 |
| PL193323B1 (pl) | 2007-02-28 |
| BG64317B1 (bg) | 2004-09-30 |
| EP1053239A1 (en) | 2000-11-22 |
| HK1033308A1 (en) | 2001-08-24 |
| AU766441B2 (en) | 2003-10-16 |
| DE69904804T2 (de) | 2003-11-06 |
| NO20004053D0 (no) | 2000-08-11 |
| ES2192035T3 (es) | 2003-09-16 |
| CA2320943A1 (en) | 1999-09-19 |
| AU2677399A (en) | 1999-08-30 |
| TR200003094T2 (tr) | 2001-01-22 |
| WO1999041256A1 (en) | 1999-08-19 |
| KR20010040935A (ko) | 2001-05-15 |
| DE69904804D1 (de) | 2003-02-13 |
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