IL137508A0 - Glucocorticoid-selective anti-inflammatory agents - Google Patents
Glucocorticoid-selective anti-inflammatory agentsInfo
- Publication number
- IL137508A0 IL137508A0 IL13750899A IL13750899A IL137508A0 IL 137508 A0 IL137508 A0 IL 137508A0 IL 13750899 A IL13750899 A IL 13750899A IL 13750899 A IL13750899 A IL 13750899A IL 137508 A0 IL137508 A0 IL 137508A0
- Authority
- IL
- Israel
- Prior art keywords
- glucocorticoid
- inflammatory agents
- selective anti
- mammal
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2394798A | 1998-02-13 | 1998-02-13 | |
| US24783199A | 1999-02-10 | 1999-02-10 | |
| PCT/US1999/003127 WO1999041256A1 (en) | 1998-02-13 | 1999-02-12 | Glucocorticoid-selective anti-inflammatory agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL137508A0 true IL137508A0 (en) | 2001-07-24 |
Family
ID=26697833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13750899A IL137508A0 (en) | 1998-02-13 | 1999-02-12 | Glucocorticoid-selective anti-inflammatory agents |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1053239B1 (ko) |
| JP (1) | JP2002503665A (ko) |
| KR (1) | KR20010040935A (ko) |
| CN (1) | CN1119348C (ko) |
| AT (1) | ATE230749T1 (ko) |
| AU (1) | AU766441B2 (ko) |
| BG (1) | BG64317B1 (ko) |
| BR (1) | BR9907788A (ko) |
| CA (1) | CA2320943A1 (ko) |
| DE (1) | DE69904804T2 (ko) |
| DK (1) | DK1053239T3 (ko) |
| ES (1) | ES2192035T3 (ko) |
| HK (1) | HK1033308A1 (ko) |
| HU (1) | HUP0100460A3 (ko) |
| IL (1) | IL137508A0 (ko) |
| NO (1) | NO20004053L (ko) |
| NZ (1) | NZ506013A (ko) |
| PL (1) | PL193323B1 (ko) |
| SK (1) | SK284689B6 (ko) |
| TR (1) | TR200003094T2 (ko) |
| WO (1) | WO1999041256A1 (ko) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6506766B1 (en) | 1998-02-13 | 2003-01-14 | Abbott Laboratories | Glucocortiocoid-selective antinflammatory agents |
| US6436986B1 (en) | 1999-09-01 | 2002-08-20 | Abbott Laboratories | Glucocorticoid receptor antagonists for treatment of diabetes |
| US6593480B2 (en) * | 1999-09-01 | 2003-07-15 | Abbott Laboratories | Glucocorticoid receptor antagonists for treatment of diabetes |
| CO5180649A1 (es) * | 1999-09-01 | 2002-07-30 | Abbott Lab | Antagonistas de los receptores de los glucocorticoides para el tratamiento de la diabetes para el tratamiento de la diabetes |
| US6329534B1 (en) | 1999-09-01 | 2001-12-11 | Abbott Laboratories | Glucocorticoid receptor antagonists for treatment of diabetes |
| EP1201660B1 (en) | 2000-10-30 | 2005-08-31 | Pfizer Products Inc. | Glucocorticoid receptor modulators |
| WO2003002548A1 (en) * | 2001-06-29 | 2003-01-09 | Abbott Laboratories | A process for the preparation of chiral glucocorticoid receptor agents |
| US6608216B2 (en) | 2001-06-29 | 2003-08-19 | Abbott Laboratories | Process for the preparation of chiral glucocorticoid receptor agents |
| US6518430B1 (en) * | 2001-09-21 | 2003-02-11 | Abbott Laboratories | Process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-F]quinolines and derivatives thereof |
| WO2003059899A1 (en) | 2002-01-14 | 2003-07-24 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical formulations containing them and uses thereof |
| RS51097B (sr) | 2002-03-26 | 2010-10-31 | Boehringer Ingelheim Pharmaceuticals Inc. | Glukokortikoidni mimetici,postupci za njihovo dobijanje, farmaceutski preparati i njihova primena |
| AU2003230700A1 (en) | 2002-03-26 | 2003-10-13 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| CA2481320A1 (en) | 2002-04-11 | 2003-10-23 | Merck & Co., Inc. | 1h-benzo[f]indazol-5-yl derivatives as selective glucocorticoid receptor modulators |
| US7186864B2 (en) | 2002-05-29 | 2007-03-06 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| US7074806B2 (en) | 2002-06-06 | 2006-07-11 | Boehringer Ingelheim Pharmaceuticals, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| WO2004018429A2 (en) | 2002-08-21 | 2004-03-04 | Boehringer Ingelheim Pharmaceuticals, Inc. | Substituted hihydroquinolines as glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof |
| TW200410968A (en) | 2002-10-11 | 2004-07-01 | Ligand Pharm Inc | 5-cycloalkenyl 5H-chromeno[3,4-f]quinoline derivatives as selective progesterone receptor modulator compounds |
| WO2004033459A1 (en) * | 2002-10-11 | 2004-04-22 | Ligand Pharmaceuticals Incorporated | 5-(1',1'-CYCLOALKYL/ALKENYL)METHYLIDENE 1,2-DIHYDRO-5H-CHROMENO[3,4-f]QUINOLINES AS SELECTIVE PROGESTERONE RECEPTOR MODULATOR COMPOUNDS |
| DE20301728U1 (de) | 2002-10-11 | 2004-03-11 | Ligand Pharmaceuticals, Inc., San Diego | 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen |
| KR20050109922A (ko) | 2003-01-03 | 2005-11-22 | 베링거 인겔하임 파마슈티칼즈, 인코포레이티드 | 1-프로판올과 1-프로필아민 유도체 및 글루코코르티코이드리간드로서의 이들의 용도 |
| US20070088042A1 (en) | 2004-09-09 | 2007-04-19 | Meissner Robert S | Fluorinated 4-azasteroid derivatives as androgen receptor modulators |
| US7235662B2 (en) | 2003-06-11 | 2007-06-26 | Bristol-Myers Squibb Company | Modulators of the glucocorticoid receptor and method |
| US8097606B2 (en) | 2003-07-23 | 2012-01-17 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of catatonia |
| UY28526A1 (es) | 2003-09-24 | 2005-04-29 | Boehringer Ingelheim Pharma | Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos |
| EP1675839B1 (en) | 2003-10-16 | 2007-07-11 | Boehringer Ingelheim Pharmaceuticals Inc. | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols |
| US7795272B2 (en) | 2004-03-13 | 2010-09-14 | Boehringer Ingelheim Pharmaceutical, Inc. | Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof |
| DE602005015027D1 (de) | 2004-12-27 | 2009-07-30 | Boehringer Ingelheim Pharma | Glucocorticoid-mimetika, verfahren zu deren herstellung, pharmazeutische zusammensetzungen und deren verwendung |
| CN102304124B (zh) * | 2005-09-14 | 2014-10-22 | 参天制药株式会社 | 具有糖皮质激素受体结合活性的1,2-二氢喹啉衍生物 |
| WO2010147947A2 (en) | 2009-06-16 | 2010-12-23 | Schering Corporation | NOVEL [3,2-c] HETEROARYL STEROIDS AS GLUCOCORTICOID RECEPTOR AGONISTS, COMPOSITIONS AND USES THEREOF |
| CA2769563A1 (en) | 2009-07-31 | 2011-02-10 | Cadila Healthcare Limited | Novel compounds as modulators of glucocorticoid receptors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ300739A (en) * | 1994-12-22 | 2000-05-26 | Ligand Pharm Inc | Steroid receptor modulator compounds |
-
1999
- 1999-02-12 ES ES99906996T patent/ES2192035T3/es not_active Expired - Lifetime
- 1999-02-12 JP JP2000531449A patent/JP2002503665A/ja active Pending
- 1999-02-12 HU HU0100460A patent/HUP0100460A3/hu unknown
- 1999-02-12 BR BR9907788-4A patent/BR9907788A/pt not_active Application Discontinuation
- 1999-02-12 TR TR2000/03094T patent/TR200003094T2/xx unknown
- 1999-02-12 AU AU26773/99A patent/AU766441B2/en not_active Ceased
- 1999-02-12 PL PL343018A patent/PL193323B1/pl not_active IP Right Cessation
- 1999-02-12 DK DK99906996T patent/DK1053239T3/da active
- 1999-02-12 SK SK1197-2000A patent/SK284689B6/sk unknown
- 1999-02-12 CN CN99804902A patent/CN1119348C/zh not_active Expired - Fee Related
- 1999-02-12 WO PCT/US1999/003127 patent/WO1999041256A1/en active IP Right Grant
- 1999-02-12 CA CA002320943A patent/CA2320943A1/en not_active Abandoned
- 1999-02-12 KR KR1020007008850A patent/KR20010040935A/ko not_active Application Discontinuation
- 1999-02-12 NZ NZ506013A patent/NZ506013A/xx unknown
- 1999-02-12 EP EP99906996A patent/EP1053239B1/en not_active Expired - Lifetime
- 1999-02-12 DE DE69904804T patent/DE69904804T2/de not_active Expired - Lifetime
- 1999-02-12 AT AT99906996T patent/ATE230749T1/de active
- 1999-02-12 IL IL13750899A patent/IL137508A0/xx unknown
-
2000
- 2000-08-11 NO NO20004053A patent/NO20004053L/no not_active Application Discontinuation
- 2000-08-28 BG BG104719A patent/BG64317B1/bg unknown
-
2001
- 2001-04-19 HK HK01102793A patent/HK1033308A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BG64317B1 (bg) | 2004-09-30 |
| TR200003094T2 (tr) | 2001-01-22 |
| HUP0100460A2 (hu) | 2001-09-28 |
| KR20010040935A (ko) | 2001-05-15 |
| JP2002503665A (ja) | 2002-02-05 |
| HUP0100460A3 (en) | 2003-03-28 |
| CN1119348C (zh) | 2003-08-27 |
| ES2192035T3 (es) | 2003-09-16 |
| WO1999041256A1 (en) | 1999-08-19 |
| AU2677399A (en) | 1999-08-30 |
| NZ506013A (en) | 2003-03-28 |
| NO20004053L (no) | 2000-09-11 |
| ATE230749T1 (de) | 2003-01-15 |
| CA2320943A1 (en) | 1999-09-19 |
| SK11972000A3 (sk) | 2001-08-06 |
| NO20004053D0 (no) | 2000-08-11 |
| SK284689B6 (sk) | 2005-09-08 |
| PL343018A1 (en) | 2001-07-30 |
| BG104719A (en) | 2001-05-31 |
| AU766441B2 (en) | 2003-10-16 |
| BR9907788A (pt) | 2001-10-30 |
| DK1053239T3 (da) | 2003-04-22 |
| HK1033308A1 (en) | 2001-08-24 |
| DE69904804T2 (de) | 2003-11-06 |
| CN1296486A (zh) | 2001-05-23 |
| DE69904804D1 (de) | 2003-02-13 |
| PL193323B1 (pl) | 2007-02-28 |
| EP1053239A1 (en) | 2000-11-22 |
| EP1053239B1 (en) | 2003-01-08 |
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