IL137508A0 - Glucocorticoid-selective anti-inflammatory agents - Google Patents

Glucocorticoid-selective anti-inflammatory agents

Info

Publication number
IL137508A0
IL137508A0 IL13750899A IL13750899A IL137508A0 IL 137508 A0 IL137508 A0 IL 137508A0 IL 13750899 A IL13750899 A IL 13750899A IL 13750899 A IL13750899 A IL 13750899A IL 137508 A0 IL137508 A0 IL 137508A0
Authority
IL
Israel
Prior art keywords
glucocorticoid
inflammatory agents
selective anti
mammal
compounds
Prior art date
Application number
IL13750899A
Other languages
English (en)
Original Assignee
Abbott Lab
Ligand Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab, Ligand Pharm Inc filed Critical Abbott Lab
Publication of IL137508A0 publication Critical patent/IL137508A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL13750899A 1998-02-13 1999-02-12 Glucocorticoid-selective anti-inflammatory agents IL137508A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2394798A 1998-02-13 1998-02-13
US24783199A 1999-02-10 1999-02-10
PCT/US1999/003127 WO1999041256A1 (en) 1998-02-13 1999-02-12 Glucocorticoid-selective anti-inflammatory agents

Publications (1)

Publication Number Publication Date
IL137508A0 true IL137508A0 (en) 2001-07-24

Family

ID=26697833

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13750899A IL137508A0 (en) 1998-02-13 1999-02-12 Glucocorticoid-selective anti-inflammatory agents

Country Status (21)

Country Link
EP (1) EP1053239B1 (xx)
JP (1) JP2002503665A (xx)
KR (1) KR20010040935A (xx)
CN (1) CN1119348C (xx)
AT (1) ATE230749T1 (xx)
AU (1) AU766441B2 (xx)
BG (1) BG64317B1 (xx)
BR (1) BR9907788A (xx)
CA (1) CA2320943A1 (xx)
DE (1) DE69904804T2 (xx)
DK (1) DK1053239T3 (xx)
ES (1) ES2192035T3 (xx)
HK (1) HK1033308A1 (xx)
HU (1) HUP0100460A3 (xx)
IL (1) IL137508A0 (xx)
NO (1) NO20004053L (xx)
NZ (1) NZ506013A (xx)
PL (1) PL193323B1 (xx)
SK (1) SK284689B6 (xx)
TR (1) TR200003094T2 (xx)
WO (1) WO1999041256A1 (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506766B1 (en) * 1998-02-13 2003-01-14 Abbott Laboratories Glucocortiocoid-selective antinflammatory agents
CO5180649A1 (es) * 1999-09-01 2002-07-30 Abbott Lab Antagonistas de los receptores de los glucocorticoides para el tratamiento de la diabetes para el tratamiento de la diabetes
US6329534B1 (en) 1999-09-01 2001-12-11 Abbott Laboratories Glucocorticoid receptor antagonists for treatment of diabetes
US6593480B2 (en) 1999-09-01 2003-07-15 Abbott Laboratories Glucocorticoid receptor antagonists for treatment of diabetes
US6436986B1 (en) 1999-09-01 2002-08-20 Abbott Laboratories Glucocorticoid receptor antagonists for treatment of diabetes
EP1201660B1 (en) 2000-10-30 2005-08-31 Pfizer Products Inc. Glucocorticoid receptor modulators
WO2003002548A1 (en) * 2001-06-29 2003-01-09 Abbott Laboratories A process for the preparation of chiral glucocorticoid receptor agents
US6608216B2 (en) 2001-06-29 2003-08-19 Abbott Laboratories Process for the preparation of chiral glucocorticoid receptor agents
US6518430B1 (en) 2001-09-21 2003-02-11 Abbott Laboratories Process for the preparation of 5-(substituted)-10-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-F]quinolines and derivatives thereof
US6960581B2 (en) 2002-01-14 2005-11-01 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical formulations, and uses thereof
PT1490062E (pt) 2002-03-26 2008-01-30 Boehringer Ingelheim Pharma Miméticos de glucocorticóides, métodos para a sua preparação, composições farmacêuticas e suas utilizações
CA2477764A1 (en) 2002-03-26 2003-10-09 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
AU2003221706B2 (en) 2002-04-11 2008-02-28 Merck Sharp & Dohme Corp. 1H-Benzo[F]indazol-5-YL derivatives as selective glucocorticoid receptor modulators
US7186864B2 (en) 2002-05-29 2007-03-06 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
US7074806B2 (en) 2002-06-06 2006-07-11 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
ATE403648T1 (de) 2002-08-21 2008-08-15 Boehringer Ingelheim Pharma Substituierte dihydrochinoline als glucocorticoid-mmimetika,verfahren zu deren herstellung, pharmazeutische zubereitungen und deren verwendung
MXPA05003800A (es) 2002-10-11 2005-06-08 Ligand Pharm Inc 5-(1¦,1¦-cicloalquil/alquenil)metiliden 1,2-dihidro-5h- cromeno[3,4f]quinolinas como compuestos moduladores de receptor de progesterona selectivos.
MXPA05003721A (es) * 2002-10-11 2005-06-17 Ligand Pharm Inc Derivados de 5-cicloalquenilo-5h-cromeno[3,4-f]quinolina como compuestos moduladores, selectivos de receptores de progesterona.
DE20301728U1 (de) 2002-10-11 2004-03-11 Ligand Pharmaceuticals, Inc., San Diego 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen
CA2512257A1 (en) 2003-01-03 2004-07-29 Boehringer Ingelheim Pharmaceuticals, Inc. 1-propanol and 1-propylamine derivatives and their use as glucocorticoid ligands
US20070088042A1 (en) 2004-09-09 2007-04-19 Meissner Robert S Fluorinated 4-azasteroid derivatives as androgen receptor modulators
US7235662B2 (en) 2003-06-11 2007-06-26 Bristol-Myers Squibb Company Modulators of the glucocorticoid receptor and method
US8097606B2 (en) 2003-07-23 2012-01-17 Corcept Therapeutics, Inc. Antiglucocorticoids for the treatment of catatonia
UY28526A1 (es) 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
ATE366726T1 (de) 2003-10-16 2007-08-15 Boehringer Ingelheim Pharma Stereoselektive synthese bestimmter trifluormethylsubstituierter alkohole
US7795272B2 (en) 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
EP1836166B1 (en) 2004-12-27 2009-06-17 Boehringer Ingelheim Pharmaceuticals Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
CN102229562B (zh) * 2005-09-14 2013-11-13 参天制药株式会社 具有糖皮质激素受体结合活性的1,2-二氢喹啉衍生物
MX2011013679A (es) 2009-06-16 2012-01-20 Schering Corp Esteroides de heteroarilo [3.2-c] novedosos como agonistas de receptor de glucocorticoide composiciones y uso de los mismos.
CA2769563A1 (en) 2009-07-31 2011-02-10 Cadila Healthcare Limited Novel compounds as modulators of glucocorticoid receptors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0800519T3 (da) * 1994-12-22 2004-03-01 Ligand Pharm Inc Steroidreceptormodulatorforbindelser og fremgangsmåder

Also Published As

Publication number Publication date
EP1053239A1 (en) 2000-11-22
WO1999041256A1 (en) 1999-08-19
SK284689B6 (sk) 2005-09-08
NO20004053L (no) 2000-09-11
DK1053239T3 (da) 2003-04-22
PL343018A1 (en) 2001-07-30
PL193323B1 (pl) 2007-02-28
AU766441B2 (en) 2003-10-16
BR9907788A (pt) 2001-10-30
JP2002503665A (ja) 2002-02-05
CA2320943A1 (en) 1999-09-19
DE69904804D1 (de) 2003-02-13
DE69904804T2 (de) 2003-11-06
HUP0100460A2 (hu) 2001-09-28
CN1296486A (zh) 2001-05-23
HUP0100460A3 (en) 2003-03-28
KR20010040935A (ko) 2001-05-15
SK11972000A3 (sk) 2001-08-06
CN1119348C (zh) 2003-08-27
ES2192035T3 (es) 2003-09-16
NO20004053D0 (no) 2000-08-11
EP1053239B1 (en) 2003-01-08
BG64317B1 (bg) 2004-09-30
BG104719A (en) 2001-05-31
TR200003094T2 (tr) 2001-01-22
HK1033308A1 (en) 2001-08-24
AU2677399A (en) 1999-08-30
NZ506013A (en) 2003-03-28
ATE230749T1 (de) 2003-01-15

Similar Documents

Publication Publication Date Title
PL343018A1 (en) Glucocorticoid-selective anti-inflammatory agents
BG104698A (en) Glucocorticoid-selective anti-inflammatory agents
WO2002002565A3 (en) Glucocortiocoid-selective antiinflammatory agents
BG105109A (en) Cell adhesion-inhibiting anti-inflammatory compounds
BG105880A (en) Compounds useful as anti-inflammatory agents
WO1999005096A3 (en) Urokinase inhibitors
ATE296283T1 (de) Zelladhäsion- und entzündungshemmende immunosuppressive verbindungen
AU2732597A (en) Novel pharmaceutical compositions having steroid nitrate ester derivatives useful as anti-inflammatory drugs
MY133125A (en) Novel dihydroxyhexanoic acid derivatives
AU4179399A (en) Use of nmda antagonists and/or sodium channel antagonists for the treatment of inflammatory disorders
WO2000006137A3 (en) Glucocorticoid-selective anti-inflammatory agents
ZA979647B (en) Heterocyclic compounds, compositions and uses.
MY128261A (en) New substituted azetidinones as anti-inflammatory and antidegenerative agents
GB9619660D0 (en) Prevention of gastrointestinal damage
ZA979645B (en) Heterocyclic compounds, compositions and uses.
ZA979650B (en) Heterocyclic compounds, compositions and uses.
AU7150598A (en) Methods and compositions for the prevention and treatment of immunological disorders, inflammatory diseases and infections
MX9805015A (es) INHIBIDORES DE LA ENZIMA QUE CONVIERTE LA INTERLEUCINA-1 beta.
MX9703610A (es) Nuevas (5,6)-heteroaril condensado-pirimidin-4-onas 2,3 disustituidas.