SK284043B6 - Spôsob výroby azacyklohexapeptidov a medziprodukty - Google Patents

Spôsob výroby azacyklohexapeptidov a medziprodukty Download PDF

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Publication number
SK284043B6
SK284043B6 SK1694-98A SK169498A SK284043B6 SK 284043 B6 SK284043 B6 SK 284043B6 SK 169498 A SK169498 A SK 169498A SK 284043 B6 SK284043 B6 SK 284043B6
Authority
SK
Slovakia
Prior art keywords
formula
compound
acid
alkyl
carbon atoms
Prior art date
Application number
SK1694-98A
Other languages
English (en)
Slovak (sk)
Other versions
SK169498A3 (en
Inventor
William Leonard
Kevin M. Belyk
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26309664&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK284043(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9614325.0A external-priority patent/GB9614325D0/en
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of SK169498A3 publication Critical patent/SK169498A3/sk
Publication of SK284043B6 publication Critical patent/SK284043B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
SK1694-98A 1996-06-14 1997-06-10 Spôsob výroby azacyklohexapeptidov a medziprodukty SK284043B6 (sk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2048396P 1996-06-14 1996-06-14
GBGB9614325.0A GB9614325D0 (en) 1996-07-08 1996-07-08 A process for preparing certain aza cyclohexapeptides
PCT/US1997/009833 WO1997047645A1 (en) 1996-06-14 1997-06-10 A process for preparing certain aza cyclohexapeptides

Publications (2)

Publication Number Publication Date
SK169498A3 SK169498A3 (en) 1999-08-06
SK284043B6 true SK284043B6 (sk) 2004-08-03

Family

ID=26309664

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1694-98A SK284043B6 (sk) 1996-06-14 1997-06-10 Spôsob výroby azacyklohexapeptidov a medziprodukty

Country Status (25)

Country Link
EP (1) EP0912603B1 (ru)
JP (1) JP3089037B2 (ru)
KR (1) KR100341953B1 (ru)
CN (1) CN1122672C (ru)
AR (2) AR008393A3 (ru)
AT (1) ATE252112T1 (ru)
AU (1) AU712857B2 (ru)
BR (1) BR9709691B1 (ru)
CA (1) CA2256620C (ru)
CZ (2) CZ287742B6 (ru)
DE (1) DE69725580T2 (ru)
DK (1) DK0912603T3 (ru)
EA (1) EA002049B1 (ru)
ES (1) ES2208914T3 (ru)
HR (1) HRP970318B1 (ru)
HU (1) HU227427B1 (ru)
NZ (1) NZ332798A (ru)
PL (1) PL187035B1 (ru)
PT (1) PT912603E (ru)
RS (1) RS49572B (ru)
SI (1) SI0912603T1 (ru)
SK (1) SK284043B6 (ru)
TW (1) TW450975B (ru)
UA (1) UA54433C2 (ru)
WO (1) WO1997047645A1 (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU763351B2 (en) * 1998-08-28 2003-07-17 Eli Lilly And Company Reversible boronate complexes of 1,2-(cis)-diol cyclic-peptides
EP1785432A1 (en) 2005-11-15 2007-05-16 Sandoz AG Process and intermediates for the synthesis of caspofungin.
BRPI0715113A2 (pt) * 2006-07-26 2013-06-04 Sandoz Ag Sandoz Sa Sandoz Ltd formulaÇço de caspofungina
US8048853B2 (en) 2008-06-13 2011-11-01 Xellia Pharmaceuticals Aps Process for preparing pharmaceutical compound and intermediates thereof
US20100256074A1 (en) * 2008-06-25 2010-10-07 Chaim Eidelman Processes for preparing high purity aza cyclohexapeptides
CN101648994B (zh) * 2009-08-06 2012-09-05 上海天伟生物制药有限公司 一种氮杂环己肽或其药学上可接受的盐及其制备方法和用途
CN101792486A (zh) * 2010-04-12 2010-08-04 浙江海正药业股份有限公司 一种合成醋酸卡泊芬净的方法
CN102367269B (zh) 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其制备方法和用途
CN102367267B (zh) 2010-11-10 2013-09-04 上海天伟生物制药有限公司 一种卡泊芬净的制备方法
CN102367268B (zh) 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其用途
CN102219833A (zh) * 2011-04-18 2011-10-19 深圳市健元医药科技有限公司 一种更加安全的棘白菌类抗真菌药的制备方法
CN102746384B (zh) 2011-04-22 2016-01-20 上海天伟生物制药有限公司 一种高纯度的卡泊芬净或其盐及其制备方法和用途
CN107778360B (zh) * 2016-08-27 2020-06-12 鲁南制药集团股份有限公司 一种制备醋酸卡泊芬净的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5552521A (en) * 1995-02-10 1996-09-03 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides

Also Published As

Publication number Publication date
EP0912603B1 (en) 2003-10-15
DK0912603T3 (da) 2004-02-09
NZ332798A (en) 2000-05-26
EA002049B1 (ru) 2001-12-24
CA2256620A1 (en) 1997-12-18
WO1997047645A1 (en) 1997-12-18
CZ411998A3 (cs) 1999-05-12
AU712857B2 (en) 1999-11-18
CZ287742B6 (en) 2001-01-17
AR017997A3 (es) 2001-10-31
YU56098A (sh) 1999-09-27
BR9709691B1 (pt) 2010-02-23
BR9709691A (pt) 1999-08-10
CN1122672C (zh) 2003-10-01
HUP9903678A3 (en) 2001-01-29
KR20000016564A (ko) 2000-03-25
DE69725580T2 (de) 2004-08-05
CN1222161A (zh) 1999-07-07
JP3089037B2 (ja) 2000-09-18
AR008393A3 (es) 2000-01-19
PL330400A1 (en) 1999-05-10
JPH11514665A (ja) 1999-12-14
SK169498A3 (en) 1999-08-06
RS49572B (sr) 2007-04-10
HU227427B1 (hu) 2011-05-30
ATE252112T1 (de) 2003-11-15
AU3303997A (en) 1998-01-07
TW450975B (en) 2001-08-21
CA2256620C (en) 2003-12-30
DE69725580D1 (de) 2003-11-20
HUP9903678A2 (hu) 2000-04-28
PT912603E (pt) 2004-02-27
EP0912603A1 (en) 1999-05-06
KR100341953B1 (ko) 2002-10-31
ES2208914T3 (es) 2004-06-16
EA199900027A1 (ru) 1999-06-24
HRP970318B1 (en) 2002-06-30
UA54433C2 (ru) 2003-03-17
CZ287743B6 (cs) 2001-01-17
SI0912603T1 (en) 2004-02-29
PL187035B1 (pl) 2004-05-31
HRP970318A2 (en) 1998-08-31

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Legal Events

Date Code Title Description
TC4A Change of owner's name

Owner name: MERCK SHARP & DOHME CORP., RAHWAY, NJ, US

Effective date: 20100203

PC4A Assignment and transfer of rights

Owner name: SCHERING CORPORATION, KENILWORTH, NEW JERSEY, US

Free format text: FORMER OWNER: MERCK SHARP & DOHME CORP., RAHWAY, NJ, US

Effective date: 20121122

TC4A Change of owner's name

Owner name: MERCK SHARP & DOHME CORP., RAHWAY, NJ, US

Effective date: 20121122

MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20150610