AR008393A3 - Un procedimiento para preparar compuestos aza ciclohexapeptidos y compuestos para su exclusivo uso en dicho procedimiento - Google Patents

Un procedimiento para preparar compuestos aza ciclohexapeptidos y compuestos para su exclusivo uso en dicho procedimiento

Info

Publication number
AR008393A3
AR008393A3 ARP970102613A ARP970102613A AR008393A3 AR 008393 A3 AR008393 A3 AR 008393A3 AR P970102613 A ARP970102613 A AR P970102613A AR P970102613 A ARP970102613 A AR P970102613A AR 008393 A3 AR008393 A3 AR 008393A3
Authority
AR
Argentina
Prior art keywords
procedure
compounds
exclusive use
alkyl
preparing aza
Prior art date
Application number
ARP970102613A
Other languages
English (en)
Original Assignee
Merck Sharp & Dohme
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26309664&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=AR008393(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9614325.0A external-priority patent/GB9614325D0/en
Application filed by Merck Sharp & Dohme filed Critical Merck Sharp & Dohme
Publication of AR008393A3 publication Critical patent/AR008393A3/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Proceso para preparar aza ciclohexapéptidos de formula I en donde: R1 es CH2CH2NH2 o CH2-CONH2; R1 es alquil C9-C21, alquenil C9-C21, alcoxifenil C1-C10alcoxinaftil C1-C10; o alcoxiterfenil C1-C10; R11 es H, alquil C1-C4, alquenil C3-C4, (CH2)2-4 OH, o (CH2)2-6NRIVRV, R111 es H, alquil C1-C4 alquenil C3-C4,(CH2)2-4OH, (CH2)2-6NRIVRV, o R11 y R111 tomados juntos son (CH2)4, (CH2)5 (CH2)2O(CH2)2OCH2)2NH(CH2)2; RIV es H O alquil C1-C4, RV es H o alquil C1-C4, Qes N u O o sus sales deadici on de ácido de los mismos.
ARP970102613A 1996-06-14 1997-06-13 Un procedimiento para preparar compuestos aza ciclohexapeptidos y compuestos para su exclusivo uso en dicho procedimiento AR008393A3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2048396P 1996-06-14 1996-06-14
GBGB9614325.0A GB9614325D0 (en) 1996-07-08 1996-07-08 A process for preparing certain aza cyclohexapeptides

Publications (1)

Publication Number Publication Date
AR008393A3 true AR008393A3 (es) 2000-01-19

Family

ID=26309664

Family Applications (2)

Application Number Title Priority Date Filing Date
ARP970102613A AR008393A3 (es) 1996-06-14 1997-06-13 Un procedimiento para preparar compuestos aza ciclohexapeptidos y compuestos para su exclusivo uso en dicho procedimiento
ARP980101679A AR017997A3 (es) 1996-06-14 1998-04-13 Procedimiento para preparar compuestos aza ciclohexapeptidos y compuestos para su exclusivo uso en dicho procedimiento

Family Applications After (1)

Application Number Title Priority Date Filing Date
ARP980101679A AR017997A3 (es) 1996-06-14 1998-04-13 Procedimiento para preparar compuestos aza ciclohexapeptidos y compuestos para su exclusivo uso en dicho procedimiento

Country Status (25)

Country Link
EP (1) EP0912603B1 (es)
JP (1) JP3089037B2 (es)
KR (1) KR100341953B1 (es)
CN (1) CN1122672C (es)
AR (2) AR008393A3 (es)
AT (1) ATE252112T1 (es)
AU (1) AU712857B2 (es)
BR (1) BR9709691B1 (es)
CA (1) CA2256620C (es)
CZ (2) CZ287742B6 (es)
DE (1) DE69725580T2 (es)
DK (1) DK0912603T3 (es)
EA (1) EA002049B1 (es)
ES (1) ES2208914T3 (es)
HR (1) HRP970318B1 (es)
HU (1) HU227427B1 (es)
NZ (1) NZ332798A (es)
PL (1) PL187035B1 (es)
PT (1) PT912603E (es)
RS (1) RS49572B (es)
SI (1) SI0912603T1 (es)
SK (1) SK284043B6 (es)
TW (1) TW450975B (es)
UA (1) UA54433C2 (es)
WO (1) WO1997047645A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE267210T1 (de) * 1998-08-28 2004-06-15 Lilly Co Eli Reversible borkomplexe von 1,2-(cis)-diol zyklischen peptiden
EP1785432A1 (en) 2005-11-15 2007-05-16 Sandoz AG Process and intermediates for the synthesis of caspofungin.
SI2049142T2 (sl) 2006-07-26 2016-04-29 Sandoz Ag Formulacije kaspofungina
US8048853B2 (en) 2008-06-13 2011-11-01 Xellia Pharmaceuticals Aps Process for preparing pharmaceutical compound and intermediates thereof
EP2240507A2 (en) * 2008-06-25 2010-10-20 TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság Processes for preparing high purity aza cyclohexapeptides
CN101648994B (zh) * 2009-08-06 2012-09-05 上海天伟生物制药有限公司 一种氮杂环己肽或其药学上可接受的盐及其制备方法和用途
CN101792486A (zh) * 2010-04-12 2010-08-04 浙江海正药业股份有限公司 一种合成醋酸卡泊芬净的方法
CN102367267B (zh) 2010-11-10 2013-09-04 上海天伟生物制药有限公司 一种卡泊芬净的制备方法
CN102367268B (zh) 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其用途
CN102367269B (zh) 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其制备方法和用途
CN102219833A (zh) * 2011-04-18 2011-10-19 深圳市健元医药科技有限公司 一种更加安全的棘白菌类抗真菌药的制备方法
CN102746384B (zh) 2011-04-22 2016-01-20 上海天伟生物制药有限公司 一种高纯度的卡泊芬净或其盐及其制备方法和用途
CN107778360B (zh) * 2016-08-27 2020-06-12 鲁南制药集团股份有限公司 一种制备醋酸卡泊芬净的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5552521A (en) * 1995-02-10 1996-09-03 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides

Also Published As

Publication number Publication date
AU3303997A (en) 1998-01-07
YU56098A (sh) 1999-09-27
ES2208914T3 (es) 2004-06-16
AR017997A3 (es) 2001-10-31
ATE252112T1 (de) 2003-11-15
AU712857B2 (en) 1999-11-18
CA2256620A1 (en) 1997-12-18
KR100341953B1 (ko) 2002-10-31
SK284043B6 (sk) 2004-08-03
CN1122672C (zh) 2003-10-01
TW450975B (en) 2001-08-21
EP0912603A1 (en) 1999-05-06
CZ411998A3 (cs) 1999-05-12
CA2256620C (en) 2003-12-30
DE69725580T2 (de) 2004-08-05
CN1222161A (zh) 1999-07-07
HU227427B1 (hu) 2011-05-30
RS49572B (sr) 2007-04-10
WO1997047645A1 (en) 1997-12-18
HRP970318B1 (en) 2002-06-30
PL330400A1 (en) 1999-05-10
SI0912603T1 (en) 2004-02-29
CZ287742B6 (en) 2001-01-17
DE69725580D1 (de) 2003-11-20
EA002049B1 (ru) 2001-12-24
NZ332798A (en) 2000-05-26
BR9709691A (pt) 1999-08-10
UA54433C2 (uk) 2003-03-17
HUP9903678A3 (en) 2001-01-29
EA199900027A1 (ru) 1999-06-24
KR20000016564A (ko) 2000-03-25
BR9709691B1 (pt) 2010-02-23
SK169498A3 (en) 1999-08-06
PL187035B1 (pl) 2004-05-31
CZ287743B6 (cs) 2001-01-17
JPH11514665A (ja) 1999-12-14
HRP970318A2 (en) 1998-08-31
JP3089037B2 (ja) 2000-09-18
EP0912603B1 (en) 2003-10-15
PT912603E (pt) 2004-02-27
DK0912603T3 (da) 2004-02-09
HUP9903678A2 (hu) 2000-04-28

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