DE69725580D1 - Prozess zur herstellung von aza zyclohexapeptide - Google Patents

Prozess zur herstellung von aza zyclohexapeptide

Info

Publication number
DE69725580D1
DE69725580D1 DE69725580T DE69725580T DE69725580D1 DE 69725580 D1 DE69725580 D1 DE 69725580D1 DE 69725580 T DE69725580 T DE 69725580T DE 69725580 T DE69725580 T DE 69725580T DE 69725580 D1 DE69725580 D1 DE 69725580D1
Authority
DE
Germany
Prior art keywords
production
aza cyclohexapeptide
cyclohexapeptide
aza
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69725580T
Other languages
English (en)
Other versions
DE69725580T2 (de
Inventor
William Leonard
M Belyk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme LLC
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26309664&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69725580(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GBGB9614325.0A external-priority patent/GB9614325D0/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of DE69725580D1 publication Critical patent/DE69725580D1/de
Application granted granted Critical
Publication of DE69725580T2 publication Critical patent/DE69725580T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69725580T 1996-06-14 1997-06-10 Prozess zur herstellung von aza zyclohexapeptide Expired - Lifetime DE69725580T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US2048396P 1996-06-14 1996-06-14
US20483P 1996-06-14
GBGB9614325.0A GB9614325D0 (en) 1996-07-08 1996-07-08 A process for preparing certain aza cyclohexapeptides
GB9614325 1996-07-08
PCT/US1997/009833 WO1997047645A1 (en) 1996-06-14 1997-06-10 A process for preparing certain aza cyclohexapeptides

Publications (2)

Publication Number Publication Date
DE69725580D1 true DE69725580D1 (de) 2003-11-20
DE69725580T2 DE69725580T2 (de) 2004-08-05

Family

ID=26309664

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69725580T Expired - Lifetime DE69725580T2 (de) 1996-06-14 1997-06-10 Prozess zur herstellung von aza zyclohexapeptide

Country Status (25)

Country Link
EP (1) EP0912603B1 (de)
JP (1) JP3089037B2 (de)
KR (1) KR100341953B1 (de)
CN (1) CN1122672C (de)
AR (2) AR008393A3 (de)
AT (1) ATE252112T1 (de)
AU (1) AU712857B2 (de)
BR (1) BR9709691B1 (de)
CA (1) CA2256620C (de)
CZ (2) CZ287742B6 (de)
DE (1) DE69725580T2 (de)
DK (1) DK0912603T3 (de)
EA (1) EA002049B1 (de)
ES (1) ES2208914T3 (de)
HR (1) HRP970318B1 (de)
HU (1) HU227427B1 (de)
NZ (1) NZ332798A (de)
PL (1) PL187035B1 (de)
PT (1) PT912603E (de)
RS (1) RS49572B (de)
SI (1) SI0912603T1 (de)
SK (1) SK284043B6 (de)
TW (1) TW450975B (de)
UA (1) UA54433C2 (de)
WO (1) WO1997047645A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000012540A1 (en) * 1998-08-28 2000-03-09 Eli Lilly And Company Reversible boronate complexes of 1,2-cis-diol cyclic-peptides
EP1785432A1 (de) 2005-11-15 2007-05-16 Sandoz AG Verfahren und Zwischenprodukte zur Synthese des Caspofungins
KR101536781B1 (ko) 2006-07-26 2015-07-14 산도즈 아게 카스포펀진 제형
US8048853B2 (en) 2008-06-13 2011-11-01 Xellia Pharmaceuticals Aps Process for preparing pharmaceutical compound and intermediates thereof
US20100256074A1 (en) * 2008-06-25 2010-10-07 Chaim Eidelman Processes for preparing high purity aza cyclohexapeptides
CN101648994B (zh) * 2009-08-06 2012-09-05 上海天伟生物制药有限公司 一种氮杂环己肽或其药学上可接受的盐及其制备方法和用途
CN101792486A (zh) * 2010-04-12 2010-08-04 浙江海正药业股份有限公司 一种合成醋酸卡泊芬净的方法
CN102367269B (zh) 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其制备方法和用途
CN102367267B (zh) 2010-11-10 2013-09-04 上海天伟生物制药有限公司 一种卡泊芬净的制备方法
CN102367268B (zh) * 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其用途
CN102219833A (zh) * 2011-04-18 2011-10-19 深圳市健元医药科技有限公司 一种更加安全的棘白菌类抗真菌药的制备方法
CN102746384B (zh) 2011-04-22 2016-01-20 上海天伟生物制药有限公司 一种高纯度的卡泊芬净或其盐及其制备方法和用途
CN107778360B (zh) * 2016-08-27 2020-06-12 鲁南制药集团股份有限公司 一种制备醋酸卡泊芬净的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5552521A (en) * 1995-02-10 1996-09-03 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides

Also Published As

Publication number Publication date
CZ411998A3 (cs) 1999-05-12
CN1222161A (zh) 1999-07-07
CN1122672C (zh) 2003-10-01
AR017997A3 (es) 2001-10-31
BR9709691A (pt) 1999-08-10
JPH11514665A (ja) 1999-12-14
ATE252112T1 (de) 2003-11-15
DK0912603T3 (da) 2004-02-09
EA199900027A1 (ru) 1999-06-24
EA002049B1 (ru) 2001-12-24
AR008393A3 (es) 2000-01-19
HRP970318B1 (en) 2002-06-30
JP3089037B2 (ja) 2000-09-18
CZ287743B6 (cs) 2001-01-17
HU227427B1 (hu) 2011-05-30
EP0912603A1 (de) 1999-05-06
TW450975B (en) 2001-08-21
PT912603E (pt) 2004-02-27
SI0912603T1 (en) 2004-02-29
HUP9903678A2 (hu) 2000-04-28
YU56098A (sh) 1999-09-27
UA54433C2 (uk) 2003-03-17
AU3303997A (en) 1998-01-07
EP0912603B1 (de) 2003-10-15
RS49572B (sr) 2007-04-10
CZ287742B6 (en) 2001-01-17
SK169498A3 (en) 1999-08-06
KR20000016564A (ko) 2000-03-25
SK284043B6 (sk) 2004-08-03
AU712857B2 (en) 1999-11-18
NZ332798A (en) 2000-05-26
PL330400A1 (en) 1999-05-10
DE69725580T2 (de) 2004-08-05
BR9709691B1 (pt) 2010-02-23
CA2256620A1 (en) 1997-12-18
ES2208914T3 (es) 2004-06-16
CA2256620C (en) 2003-12-30
HRP970318A2 (en) 1998-08-31
KR100341953B1 (ko) 2002-10-31
HUP9903678A3 (en) 2001-01-29
PL187035B1 (pl) 2004-05-31
WO1997047645A1 (en) 1997-12-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: MERCK SHARP & DOHME CORP., NEW JERSEY, N.J., US